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Gene Dmel\CG9673

General Information
Symbol	Dmel\CG9673	Species	D. melanogaster
Name		Annotation symbol	CG9673
Feature type	protein_coding_gene	FlyBase ID	FBgn0030775
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	15A2-15A3	Sequence location	X:16,596,817..16,597,917 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9673 (FBgn0030775). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: serine-type endopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Peptidase S1; Peptidase S1, trypsin family, active site; Peptidase S1A, chymotrypsin-type; Trypsin-like cysteine/serine peptidase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut. Comments on Affy2 ProbeSet: ProbeSet 1631148_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9673. Gene sequence location is X:16596817..16597917.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 15A2-15A3   Limits computationally determined from genome sequence between P{EP}EP1547EP1547 and P{EP}CG4928EP1341
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9673 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9673-RA FBtr0074362  NM_132921   891   261 CG9673-RB FBtr0339830     980   261
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9673-PA   FBpp0074136   27.9   261   4.29     NP_573149   AAF48649 CG9673-PB   FBpp0308864   27.9   261   4.29
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1 (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Trypsin-like cysteine/serine peptidase domain (IPR009003) Peptidase S1, trypsin family, active site (IPR018114)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48649   AY113462 AAM29467   BI216590   BI240808   BI482230   BI578373   BI580938   CK660390   CO321819   EC051668   EC053647   EC223285   EV591578   FD585621   FD585825   FD587040   FD587051   FD587137   FD587148   GH739020   GH739719   GH745277   GH764742   GH768767   GH769108
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VXC7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 13 -- 16   embryonic midgut chamber   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    5081.3 Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut    5268.6 Adult Hindgut    1679.4 Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut  (5081.3) Larval Hindgut  (554.3) Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut  (5268.6) Adult Hindgut  (1679.4) Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut  (5081.3) Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut  (5268.6) Adult Hindgut  (1679.4) Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    5081.3 Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut    5268.6 Adult Hindgut    1679.4 Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    5081.3 Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut    5268.6 Adult Hindgut    1679.4 Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut  (5081.3) Larval Hindgut  554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut  (5268.6) Adult Hindgut  (1679.4) Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut  (5081.3) Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut  (5268.6) Adult Hindgut  1679.4 Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    5081.3 Larval Hindgut    554.3 Larval Malpighian Tubules    4.2 Larval Fat Body    1.9 Larval Salivary Gland    4.4 Larval Trachea    4.15 Larval Carcass    3.775 Adult Head    1.3 Adult Eye    5.75 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    1.2 Adult Crop    8.1 Adult Midgut    5268.6 Adult Hindgut    1679.4 Adult Malpighian Tubules    37.1 Adult Fat Body    2.1 Adult Salivary Gland    12.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    7.1 Adult Ovary    0.7 Adult Testis    5.9 Adult Male Accessory Gland    3.7 Adult Carcass    5.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1.3   NA  Eye    5.75   NA  Brain    1.6   1.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1.2   NA  Crop    8.1   5081.3  Midgut    5268.6   554.3  Hindgut    1679.4   4.2  Malpighian Tubules    no informative data   1.9  Fat Body    2.1   4.4  Salivary Gland    no informative data   NA  Heart    3.3   4.15  Trachea    NA   NA  VirginFemale Spermatheca    4.8   NA  InseminatedFemale Spermatheca    7.1   NA  Ovary    0.7   NA  Testis    5.9   NA  Male Accessory Gland    3.7   3.775  Carcass    5.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    251 digestive system, 1-day adult    537 digestive system, 4-day adult    357 digestive system, 20-day adult    507 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (64) central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  (251) digestive system, 1-day adult  (537) digestive system, 4-day adult  (357) digestive system, 20-day adult  (507) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male  26 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  (251) digestive system, 1-day adult  (537) digestive system, 4-day adult  (357) digestive system, 20-day adult  (507) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    251 digestive system, 1-day adult    537 digestive system, 4-day adult    357 digestive system, 20-day adult    507 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    251 digestive system, 1-day adult    537 digestive system, 4-day adult    357 digestive system, 20-day adult    507 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (64) central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  (251) digestive system, 1-day adult  (537) digestive system, 4-day adult  (357) digestive system, 20-day adult  (507) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male  26 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  (251) digestive system, 1-day adult  (537) digestive system, 4-day adult  (357) digestive system, 20-day adult  (507) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    64 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    1 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    251 digestive system, 1-day adult    537 digestive system, 4-day adult    357 digestive system, 20-day adult    507 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    3 carcass, larvae L3 wandering    1 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    11 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    10 accessory gland, mated 4-day male    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr    121 embryo 20-22hr    220 embryo 22-24hr    180 larva L1    145 larva L2    185 larva L3 12hr old    120 larva L3 puffstage 1-2    240 larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day    101 adult male 30day    84 adult female 01day    105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr  (47) embryo 18-20hr  (121) embryo 20-22hr  (220) embryo 22-24hr  (180) larva L1  (145) larva L2  (185) larva L3 12hr old  (120) larva L3 puffstage 1-2  (240) larva L3 puffstage 3-6  (70) larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP  (35) adult male 01day  (78) adult male 05day  (101) adult male 30day  (84) adult female 01day  (105) adult female 05day  (62) adult female 30day  (73) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr  (121) embryo 20-22hr  (220) embryo 22-24hr  (180) larva L1  (145) larva L2  (185) larva L3 12hr old  (120) larva L3 puffstage 1-2  (240) larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day  101 adult male 30day    84 adult female 01day  105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr    121 embryo 20-22hr    220 embryo 22-24hr    180 larva L1    145 larva L2    185 larva L3 12hr old    120 larva L3 puffstage 1-2    240 larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day    101 adult male 30day    84 adult female 01day    105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr    121 embryo 20-22hr    220 embryo 22-24hr    180 larva L1    145 larva L2    185 larva L3 12hr old    120 larva L3 puffstage 1-2    240 larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day    101 adult male 30day    84 adult female 01day    105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr  (47) embryo 18-20hr  (121) embryo 20-22hr  (220) embryo 22-24hr  (180) larva L1  (145) larva L2  (185) larva L3 12hr old  (120) larva L3 puffstage 1-2  (240) larva L3 puffstage 3-6  (70) larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP  (35) adult male 01day  (78) adult male 05day  (101) adult male 30day  (84) adult female 01day  (105) adult female 05day  (62) adult female 30day  (73) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr  121 embryo 20-22hr  (220) embryo 22-24hr  (180) larva L1  (145) larva L2  (185) larva L3 12hr old  120 larva L3 puffstage 1-2  (240) larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day  101 adult male 30day    84 adult female 01day  105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    2 embryo 14-16hr    14 embryo 16-18hr    47 embryo 18-20hr    121 embryo 20-22hr    220 embryo 22-24hr    180 larva L1    145 larva L2    185 larva L3 12hr old    120 larva L3 puffstage 1-2    240 larva L3 puffstage 3-6    70 larva L3 puffstage 7-9    18 white prepupae new    4 white prepupae 12hr    10 white prepupae 24hr    3 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    35 adult male 01day    78 adult male 05day    101 adult male 30day    84 adult female 01day    105 adult female 05day    62 adult female 30day    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3    221 Cadmium 50 mM 12 hrs, larvae L3    127 Cadmium 50 mM 48 hrs, 4-day adult    113 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    180 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    161 Ethanol 10% 3 hrs, larvae L3    190 Caffeine 1.5 mg/ml 4 hrs, larvae L3    139 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3    214 Rotenone 8 μg 12 hrs, larvae L3    260 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (36) cold shock, 4-day adult  (29) heat shock, 4-day adult  (99) Cadmium 50 mM 6 hrs, larvae L3  (221) Cadmium 50 mM 12 hrs, larvae L3  (127) Cadmium 50 mM 48 hrs, 4-day adult  (113) Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3  (180) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (105) Zinc 4.5 mM 48 hrs, 4-day adult  (27) Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3  (161) Ethanol 10% 3 hrs, larvae L3  (190) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (139) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult  (27) Paraquat 5 mM 48 hrs, 4-day adult  (46) Paraquat 10 mM 48 hrs, 4-day adult  (71) Rotenone 2 μg 12 hrs, larvae L3  (214) Rotenone 8 μg 12 hrs, larvae L3  (260) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3  (221) Cadmium 50 mM 12 hrs, larvae L3  (127) Cadmium 50 mM 48 hrs, 4-day adult  (113) Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3  (180) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3  (161) Ethanol 10% 3 hrs, larvae L3  (190) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (139) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3  (214) Rotenone 8 μg 12 hrs, larvae L3  (260) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3    221 Cadmium 50 mM 12 hrs, larvae L3    127 Cadmium 50 mM 48 hrs, 4-day adult    113 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    180 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    161 Ethanol 10% 3 hrs, larvae L3    190 Caffeine 1.5 mg/ml 4 hrs, larvae L3    139 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3    214 Rotenone 8 μg 12 hrs, larvae L3    260 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3    221 Cadmium 50 mM 12 hrs, larvae L3    127 Cadmium 50 mM 48 hrs, 4-day adult    113 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    180 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    161 Ethanol 10% 3 hrs, larvae L3    190 Caffeine 1.5 mg/ml 4 hrs, larvae L3    139 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3    214 Rotenone 8 μg 12 hrs, larvae L3    260 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (36) cold shock, 4-day adult  29 heat shock, 4-day adult  (99) Cadmium 50 mM 6 hrs, larvae L3  (221) Cadmium 50 mM 12 hrs, larvae L3  (127) Cadmium 50 mM 48 hrs, 4-day adult  (113) Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3  (180) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (105) Zinc 4.5 mM 48 hrs, 4-day adult  27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3  (161) Ethanol 10% 3 hrs, larvae L3  (190) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (139) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult  27 Paraquat 5 mM 48 hrs, 4-day adult  (46) Paraquat 10 mM 48 hrs, 4-day adult  (71) Rotenone 2 μg 12 hrs, larvae L3  (214) Rotenone 8 μg 12 hrs, larvae L3  (260) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3  (221) Cadmium 50 mM 12 hrs, larvae L3  127 Cadmium 50 mM 48 hrs, 4-day adult  113 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3  (180) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3  (161) Ethanol 10% 3 hrs, larvae L3  (190) Caffeine 1.5 mg/ml 4 hrs, larvae L3  139 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3  (214) Rotenone 8 μg 12 hrs, larvae L3  (260) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    36 cold shock, 4-day adult    29 heat shock, 4-day adult    99 Cadmium 50 mM 6 hrs, larvae L3    221 Cadmium 50 mM 12 hrs, larvae L3    127 Cadmium 50 mM 48 hrs, 4-day adult    113 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    180 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    105 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    161 Ethanol 10% 3 hrs, larvae L3    190 Caffeine 1.5 mg/ml 4 hrs, larvae L3    139 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    27 Paraquat 5 mM 48 hrs, 4-day adult    46 Paraquat 10 mM 48 hrs, 4-day adult    71 Rotenone 2 μg 12 hrs, larvae L3    214 Rotenone 8 μg 12 hrs, larvae L3    260 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_20 mE1_20_mRNA_expression_cluster_16
External Data & Images
Linkouts	BDGP expression data • RE37738 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030775 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9673-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG9673 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG9673GD6500 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG9673 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9673 Class Mutagen Stocks Known lesion CG9673GD6500 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9673KK111911 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9673NIG.9673R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6500} NA P{KK111911} NA P{NIG.9673R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
NOT serine-type endopeptidase activity non-traceable author statement (Ross et al., 2003) serine-type endopeptidase activity inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
proteolysis inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG9673 - 128up anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Arc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Art8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG11777 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG1218 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG1532 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG18789 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG2862 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Ccs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Elongin-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Pp4-19C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Trap1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Treh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Trx-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - Ugt anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - abs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG9673 - isoQC anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9673 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030775 DroID - A comprehensive database of gene and protein interactions. • FBgn0030775
Orthologs
OrthoDB Orthologs (12) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6DJKGS Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6DJKGS)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG9673     Drosophila simulans   Dsim\GD15728 Y   Drosophila sechellia   Dsec\GM13373 Y   Drosophila erecta   Dere\GG18230 Y   Drosophila yakuba   Dyak\GE15649 Y   Drosophila ananassae   Dana\GF22292 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21955 Y   Drosophila persimilis   Dper\GL26772 Y   Drosophila willistoni   Dwil\GK25504 Y   Drosophila virilis   Dvir\GJ18705 Y   Drosophila mojavensis   Dmoj\GI15879 Y   Drosophila grimshawi   Dgri\GH12385 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15728 Drosophila sechellia Dsec\GM13373 Drosophila erecta Dere\GG18230 Drosophila yakuba Dyak\GE15649 Drosophila ananassae Dana\GF22292 Drosophila pseudoobscura pseudoobscura Dpse\GA21955 Drosophila persimilis Dper\GL26772 Drosophila willistoni Dwil\GK25504 Drosophila virilis Dvir\GJ18705 Drosophila mojavensis Dmoj\GI15879 Drosophila grimshawi Dgri\GH12385
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v108491 P{KK111911}VIE-260B v14650 w1118; P{GD6500}v14650
Genomic Clones ( 1 )
	BACR18G21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 24 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE37738
Other clones	DPiM_RE37738
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP18929 RE23783 RE64888 RE72239 RE75188
Other clones	59675 Dmel_neb_009990_0327_1765 EC051668 EC053647 EK186448 RM01842 RM01942 RM02042 RM02142 RM02442 RM02542 RP001001790 RP001002362 RP001008047 RP001013613 RP001045335 RP001051020
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030775 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32649
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132921 RefSeq (Proteins) • NP_573149 DDBJ / EMBL / GenBank • AAF48649 AAM29467 AY113462 BI240808 Entrez Gene - A searchable database of RefSeq genes. • 32649 UniProtKB/TrEMBL • Q9VXC7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1 (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Trypsin-like cysteine/serine peptidase domain (IPR009003) Peptidase S1, trypsin family, active site (IPR018114) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE37738
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030775 DroID - A comprehensive database of gene and protein interactions. • FBgn0030775 DRSC - Results from RNAi screens. • FBgn0030775 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030775 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9673-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030775 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32649 modMine - Data generated by the modENCODE project. • FBgn0030775
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG9673 (Shah et al., 2008, Keleman et al., 2009.8.5, Carpenter et al., 2009, Japanese National Institute of Genetics, 2012.5.21) SPH81 (Ross et al., 2003)
Name Synonym
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 1 )
	Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Show all research papers ...