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Gene Dmel\mRpL22

General Information
Symbol	Dmel\mRpL22	Species	D. melanogaster
Name	mitochondrial ribosomal protein L22	Annotation symbol	CG4742
Feature type	protein_coding_gene	FlyBase ID	FBgn0030786
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	L22
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	15A7-15A8	Sequence location	X:16,677,987..16,679,125 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mitochondrial ribosomal protein L22 is referred to in FlyBase by the symbol Dmel\mRpL22 (CG4742, FBgn0030786). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process: translation. 5 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein L22, bacterial/chloroplast-type; Ribosomal protein L22/L17. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640889_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mRpL22. Gene sequence location is X:16677987..16679125.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 15A7-15A8   Limits computationally determined from genome sequence between P{EP}EP1547EP1547 and P{EP}CG4928EP1341
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mRpL22 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mRpL22-RA FBtr0074330  NM_078655   952   233
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mRpL22-PA   FBpp0074104   27.0   233   9.94     NP_523379   AAF48662
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L22/L17 (IPR001063) Ribosomal protein L22, bacterial/chloroplast-type (IPR005727)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48662   AI134624   AY070969 AAL48591   BG632673   BI166662   BI370129   BI483626   BI566101   BI567044   BI568448   BI582993   BI583385   BI624222   BI626156   BI634401   CO155316   CO285258   CO314116   CO315117   CO322468   CO333132   EC076753   EC082717   EC085304   EC202320   EC211891   EC213060   EC228275   EC231748   EC248822   EC266559   GH770361   GH781338   GH783870   GH794084   GH795894   GH801358   GH801932   GH874499   GH896960   GH913783   GH916236   GH922205   GH939956
UniProtKB/Swiss-Prot	Q9VXB5
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    229.7 Larval Midgut    164.7 Larval Hindgut    234.2 Larval Malpighian Tubules    201.6 Larval Fat Body    153.8 Larval Salivary Gland    252 Larval Trachea    190.125 Larval Carcass    213.15 Adult Head    174.3 Adult Eye    118.725 Adult Brain    223.1 Adult Thoracic-Abdominal Ganglion    191.9 Adult Crop    223.7 Adult Midgut    268.3 Adult Hindgut    290.5 Adult Malpighian Tubules    275.5 Adult Fat Body    243.2 Adult Salivary Gland    240.8 Adult Heart    217.575 Adult VirginFemale Spermatheca    276.4 Adult InseminatedFemale Spermatheca    290.9 Adult Ovary    349.7 Adult Testis    74.2 Adult Male Accessory Gland    200 Adult Carcass    195.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    174.3   NA  Eye    118.725   NA  Brain    223.1   229.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    191.9   NA  Crop    223.7   164.7  Midgut    268.3   234.2  Hindgut    290.5   201.6  Malpighian Tubules    275.5   153.8  Fat Body    243.2   252  Salivary Gland    240.8   NA  Heart    217.575   190.125  Trachea    NA   NA  VirginFemale Spermatheca    276.4   NA  InseminatedFemale Spermatheca    290.9   NA  Ovary    349.7   NA  Testis    74.2   NA  Male Accessory Gland    200   213.15  Carcass    195.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (38) central nervous system, larvae L3  (29) central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8  (28) carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female  (40) ovary, mated 4-day female  (33) testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (38) central nervous system, larvae L3  29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8  28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female  (40) ovary, mated 4-day female  (33) testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    38 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    17 head, virgin 4-day female    14 head, virgin 20-day female    13 head, mated 1-day female    13 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    21 head, mated 20-day male    20 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    17 fat body, larvae L3 wandering    16 fat body, white prepupae    18 fat body, pupae P8    28 carcass, larvae L3 wandering    24 carcass, 1-day adult    14 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    40 ovary, mated 4-day female    33 testis, mated 4-day male    18 accessory gland, mated 4-day male    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (31) embryo 04-06hr  (64) embryo 06-08hr  (59) embryo 08-10hr  (54) embryo 10-12hr  (77) embryo 12-14hr  (47) embryo 14-16hr  (59) embryo 16-18hr  (55) embryo 18-20hr  (57) embryo 20-22hr  (57) embryo 22-24hr  (50) larva L1  (72) larva L2  (72) larva L3 12hr old  (50) larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9  (27) white prepupae new  (28) white prepupae 12hr    25 white prepupae 24hr  (30) pupae 2d postWPP  (46) pupae 3d postWPP  (49) pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day  (43) adult female 05day  (51) adult female 30day  (51) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  31 embryo 04-06hr  (64) embryo 06-08hr  (59) embryo 08-10hr  (54) embryo 10-12hr  (77) embryo 12-14hr  (47) embryo 14-16hr  (59) embryo 16-18hr  (55) embryo 18-20hr  (57) embryo 20-22hr  (57) embryo 22-24hr  (50) larva L1  (72) larva L2  (72) larva L3 12hr old  (50) larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9  27 white prepupae new  28 white prepupae 12hr    25 white prepupae 24hr  30 pupae 2d postWPP  (46) pupae 3d postWPP  (49) pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day  (43) adult female 05day  (51) adult female 30day  (51) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    31 embryo 04-06hr    64 embryo 06-08hr    59 embryo 08-10hr    54 embryo 10-12hr    77 embryo 12-14hr    47 embryo 14-16hr    59 embryo 16-18hr    55 embryo 18-20hr    57 embryo 20-22hr    57 embryo 22-24hr    50 larva L1    72 larva L2    72 larva L3 12hr old    50 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    27 white prepupae new    28 white prepupae 12hr    25 white prepupae 24hr    30 pupae 2d postWPP    46 pupae 3d postWPP    49 pupae 4d postWPP    25 adult male 01day    25 adult male 05day    22 adult male 30day    19 adult female 01day    43 adult female 05day    51 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (52) Schneider line 2 Sg4  (70) embryonic 1182-4H  (63) embryonic GM2  (39) embryonic Kc167  (41) embryonic S1  (44) embryonic S3  (38) leg disc CME L1  (89) wing disc CME-W2    20 wing disc ML-DmD8  (42) wing disc ML-DmD9  (79) wing disc ML-DmD16-c3  (69) wing disc ML-DmD21  (98) wing disc ML-DmD32  (54) haltere disc ML-DmD17-c3  (59) eye-antennal disc ML-DmD11  (83) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (57) CNS ML-DmBG1-c1  (76) CNS ML-DmBG2-c2  (36) tumorous blood cells mbn2    22 ovary fGS/OSS  (33) ovary OSC  (43) ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (52) Schneider line 2 Sg4  (70) embryonic 1182-4H  (63) embryonic GM2  (39) embryonic Kc167  (41) embryonic S1  (44) embryonic S3  (38) leg disc CME L1  (89) wing disc CME-W2    20 wing disc ML-DmD8  (42) wing disc ML-DmD9  (79) wing disc ML-DmD16-c3  (69) wing disc ML-DmD21  (98) wing disc ML-DmD32  (54) haltere disc ML-DmD17-c3  (59) eye-antennal disc ML-DmD11  (83) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (57) CNS ML-DmBG1-c1  (76) CNS ML-DmBG2-c2  (36) tumorous blood cells mbn2    22 ovary fGS/OSS  (33) ovary OSC  (43) ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    52 Schneider line 2 Sg4    70 embryonic 1182-4H    63 embryonic GM2    39 embryonic Kc167    41 embryonic S1    44 embryonic S3    38 leg disc CME L1    89 wing disc CME-W2    20 wing disc ML-DmD8    42 wing disc ML-DmD9    79 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    98 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    59 eye-antennal disc ML-DmD11    83 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    57 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    36 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    43 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult  (29) Cadmium 50 mM 6 hrs, larvae L3  (27) Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3  (29) Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (29) Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult  (28) Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult  29 Cadmium 50 mM 6 hrs, larvae L3  27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3  29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult  28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    12 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    29 Caffeine 1.5 mg/ml 4 hrs, larvae L3    15 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    24 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_19 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • RE06857 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030786 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4742-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for mRpL22 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 mRpL22GD10524 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 mRpL22GD10524 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 mRpL22GD10524 trichogen cell, with Scer\GAL4pnr-MD237 mRpL22GD10524
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of mRpL22 Class Mutagen Stocks Known lesion mRpL22KG10050 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mRpL22 Class Mutagen Stocks Known lesion mRpL22GD10524 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mRpL22KK108151 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mRpL22MNPV(Op)\IE-2.T:SV5\V5,T:Ivir\HA1,T:Zzzz\His6 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes mRpL22NIG.4742R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10524} NA P{KK108151} NA P{NIG.4742R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}mRpL22KG10050 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with EMBL:AA772054 (Suzuki et al., 2001)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with EMBL:AA772054 (Suzuki et al., 2001)
Cellular Component
CV term Evidence References
mitochondrial large ribosomal subunit inferred from sequence or structural similarity with EMBL:AA772054 (Suzuki et al., 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
mRpL22 - AnxB11 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Ate1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG10175 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG10934 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG12279 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG1265 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG13321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG14508 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG14590 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG14615 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG15118 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG15576 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG16941 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG18081 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG2921 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG43444 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG4610 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG4611 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG4730 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG4825 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG4847 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG5746 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG7829 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG7849 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG8173 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - CG8735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Cct5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Cg25C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Ent2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Gs1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - LanB1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Orct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Ote anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Rab10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Rca1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - RluA-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - TM9SF4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - Vps25 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - ap anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - cpb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - dpn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - fs(1)K10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - lin-28 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - nopo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - rept anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL22 - vkg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mRpL22 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58995 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030786 DroID - A comprehensive database of gene and protein interactions. • FBgn0030786 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32662
Orthologs
OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6JDHT5 Dipteran inclusive ortholog search EOG6FFD9W Insect inclusive ortholog search EOG6VDNW0 Arthropod inclusive ortholog search EOG62V6ZP Metazoa inclusive ortholog search EOG63848G
Orthologs in Drosophila Species (EOG6JDHT5)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\mRpL22     Drosophila simulans   Dsim\GD17306 Y   Drosophila sechellia   Dsec\GM13465 Y   Drosophila erecta   Dere\GG19077 Y   Drosophila yakuba   Dyak\GE17623 Y   Drosophila ananassae   Dana\GF22663 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18397 Y   Drosophila persimilis   Dper\GL26864 Y   Drosophila willistoni   Dwil\GK14752 Y   Drosophila virilis   Dvir\GJ19341 Y   Drosophila mojavensis   Dmoj\GI15151 Y   Drosophila grimshawi   Dgri\GH24048 Y
Orthologs in non-Drosophila Dipterans (EOG6FFD9W)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001066   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001439   Anopheles gambiae Malaria mosquito  Agam\AGAP000508   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ019244   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017562
Orthologs in non-Dipteran Insects (EOG6VDNW0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\mRpL22   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013494   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18799   Atta cephalotes Leafcutter ant  Acep\ACEP13393   Camponotus floridanus Florida carpenter ant  Cflo\CFLO11063   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17127   Linepithema humile Argentine ant  Lhum\LH22188   Pogonomyrmex barbatus Red harvester ant  Pbar\PB15449   Solenopsis invicta Red fire ant  Sinv\SINV24299   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002040   Bombyx mori Silkmoth  Bmor\BGIBMGA000924   Pediculus humanus Human body louse  Phum\PHUM507230   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07037
Orthologs in non-Insect Arthropods (EOG62V6ZP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_45963   Ixodes scapularis Deer tick  Isca\ISCW000095   Ixodes scapularis Deer tick  Isca\ISCW024408
Orthologs in non-Arthropod Metazoa (EOG63848G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\mrpl-22   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007057gn   Danio rerio Zebrafish  Drer\mrpl22   Xenopus tropicalis Western clawed frog  Xtro\mrpl22   Gallus gallus Domestic chicken  Ggal\MRPL22   Mus musculus House mouse  Mmus\Mrpl22   Rattus norvegicus Norway rat  Rnor\Mrpl22   Homo sapiens Human  Hsap\MRPL22
Human Orthologs (1)
Gene OMIM HGNC Hsap\MRPL22
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17306 Drosophila sechellia Dsec\GM13465 Drosophila erecta Dere\GG19077 Drosophila yakuba Dyak\GE17623 Drosophila ananassae Dana\GF22663 Drosophila pseudoobscura pseudoobscura Dpse\GA18397 Drosophila persimilis Dper\GL26864 Drosophila willistoni Dwil\GK14752 Drosophila virilis Dvir\GJ19341 Drosophila mojavensis Dmoj\GI15151 Drosophila grimshawi Dgri\GH24048
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	14990 y1 P{SUPor-P}mRpL22KG10050
VDRC	v100730 P{KK108151}VIE-260B v21534 w1118; P{GD10524}v21534
Genomic Clones ( 2 )
	BACR18G21 BACR33D04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 42 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE06857
Other clones	DPiM_RE06857
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE56540 RE66544 RH21424 RH21983 RH35221 RH36873 RH38450 RH39896 RH63745 RH66705
Other clones	52853 62423 80633 102672 108702 119468 280817 524729 CK01.125D.E7 CK01.128A.F11 EK168624 EK188210 EK235132 EK239151 EK305829 EN05824 GH12140 RP003045448 RP003215087 RP003246856 RP003298809 RP003323204 RP003330628 RP003373051 RP003544836 RP003564475 RP003622951 RP003652805 RP003656270 RP003664324
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030786 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32662
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: mRpL22 CG4742 (Suzuki et al., 2001)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078655 RefSeq (Proteins) • NP_523379 DDBJ / EMBL / GenBank • AAF48662 AAL48591 AY070969 BI166662 Entrez Gene - A searchable database of RefSeq genes. • 32662 UniProtKB/Swiss-Prot • Q9VXB5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L22/L17 (IPR001063) Ribosomal protein L22, bacterial/chloroplast-type (IPR005727) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE06857
Linkouts
	BioGRID - A database of protein and genetic interactions • 58995 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030786 DroID - A comprehensive database of gene and protein interactions. • FBgn0030786 DRSC - Results from RNAi screens. • FBgn0030786 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030786 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4742-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030786 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32662 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32662 modMine - Data generated by the modENCODE project. • FBgn0030786
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG4742 (Pile et al., 2003, Suzuki et al., 2001, Keleman et al., 2009.8.5, Marygold et al., 2007) L22 (Suzuki et al., 2001, Ni et al., 2006) mRpL22 (Marygold et al., 2007, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	mitochondrial ribosomal protein L22 (Suzuki et al., 2001) ribosomal protein L22 (Ni et al., 2006)
Secondary FlyBase IDs
References ( 18 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Ni et al., 2006, Genes Dev. 20(14): 1959--1973 Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. [FBrf0194270] Pile et al., 2003, J. Biol. Chem. 278(39): 37840--37848 The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: Implications for the regulation of energy metabolism. [FBrf0162185] Suzuki et al., 2001, J. Biol. Chem. 276(24): 21724--21736 Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. [FBrf0136752]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]