Gene Dmel\CG9104

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General Information

Symbol

Dmel\CG9104

Species

D. melanogaster

Name

Annotation symbol

CG9104

Feature type

protein_coding_gene

FlyBase ID

FBgn0030800

Gene Model Status

Current

Stock availability

2 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

15B4-15B4

Sequence location

X:16,776,542..16,778,398 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG9104 (FBgn0030800). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: channel regulator activity. There is experimental evidence that it is involved in the biological process: dendrite morphogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nitrogen permease regulator 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1640290_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9104. Gene sequence location is X:16776542..16778398.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

15B4-15B4

Limits computationally determined from genome sequence between P{EP}EP1547^EP1547 and P{EP}CG4928^EP1341

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG9104 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.43

Gene model reviewed during 5.44

Gene model reviewed during 5.51

Low-frequency junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG9104-RA

FBtr0074348

NM_132946

1707

412

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG9104-PA

FBpp0074122

46.3

412

8.28

NP_573174

AAF48677

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Nitrogen permease regulator 2 (IPR009348)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VXA0

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		36.825
Larval Midgut		29.5
Larval Hindgut		40.9
Larval Malpighian Tubules		58.1
Larval Fat Body		36.8
Larval Salivary Gland		61.4
Larval Trachea		76.9
Larval Carcass		39.375
Adult Head		42.4
Adult Eye		46.075
Adult Brain		40.2
Adult Thoracic-Abdominal Ganglion		48.9
Adult Crop		64.1
Adult Midgut		47.3
Adult Hindgut		42.5
Adult Malpighian Tubules		78.7
Adult Fat Body		53.3
Adult Salivary Gland		47.7
Adult Heart		57.925
Adult VirginFemale Spermatheca		51.8
Adult InseminatedFemale Spermatheca		51.5
Adult Ovary		80.9
Adult Testis		10.2
Adult Male Accessory Gland		49.4
Adult Carcass		49.9
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	42.4
NA	Eye	46.075
NA	Brain	40.2
36.825	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	48.9
NA	Crop	64.1
no informative data	Midgut	no informative data
40.9	Hindgut	42.5
58.1	Malpighian Tubules	78.7
no informative data	Fat Body	53.3
61.4	Salivary Gland	47.7
NA	Heart	57.925
76.9	Trachea	NA
NA	VirginFemale Spermatheca	51.8
NA	InseminatedFemale Spermatheca	51.5
NA	Ovary	80.9
NA	Testis	no informative data
NA	Male Accessory Gland	49.4
39.375	Carcass	49.9

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		(29)
ovary, mated 4-day female		(29)
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		11
central nervous system, larvae L3		6
central nervous system, pupae P8		7
head, virgin 1-day female		7
head, virgin 4-day female		8
head, virgin 20-day female		8
head, mated 1-day female		6
head, mated 4-day female		6
head, mated 20-day female		8
head, mated 1-day male		10
head, mated 4-day male		10
head, mated 20-day male		10
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		7
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		5
fat body, pupae P8		14
carcass, larvae L3 wandering		8
carcass, 1-day adult		5
carcass, 4-day adult		9
carcass, 20-day adult		8
ovary, virgin 4-day female		29
ovary, mated 4-day female		29
testis, mated 4-day male		4
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(49)
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		(27)
adult female 30day		(30)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(49)
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		49
embryo 02-04hr		14
embryo 04-06hr		11
embryo 06-08hr		11
embryo 08-10hr		14
embryo 10-12hr		15
embryo 12-14hr		9
embryo 14-16hr		12
embryo 16-18hr		11
embryo 18-20hr		9
embryo 20-22hr		7
embryo 22-24hr		7
larva L1		14
larva L2		10
larva L3 12hr old		9
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		13
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		11
pupae 2d postWPP		10
pupae 3d postWPP		9
pupae 4d postWPP		9
adult male 01day		11
adult male 05day		11
adult male 30day		13
adult female 01day		24
adult female 05day		27
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		18
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		14
embryonic Kc167		17
embryonic S1		14
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		10
wing disc ML-DmD8		25
wing disc ML-DmD9		16
wing disc ML-DmD16-c3		19
wing disc ML-DmD21		21
wing disc ML-DmD32		17
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		16
antennal disc ML-DmD20-c5		13
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		10
tumorous blood cells mbn2		12
ovary fGS/OSS		17
ovary OSC		10
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		(32)
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		(29)
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		11
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		12
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		32
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		9
Ethanol 2.5% 3 hrs, larvae L3		29
Ethanol 5% 3 hrs, larvae L3		9
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		22
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		22
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD40282

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030800

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG9104-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG9104^GD4298

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG9104	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG9104	Mutagen	Stocks	Known lesion
CG9104^GD4298	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9104^GL00667	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9104^KK101142	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
CG9104^NIG.9104R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

dendrite morphogenesis

inferred from mutant phenotype

(Parrish et al., 2006)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function

CV term

Evidence

References

channel regulator activity

inferred from sequence or structural similarity with Saccharomyces NPR2

(FlyBase, 1992-)

Biological Process

CV term

Evidence

References

proline transport

inferred from sequence or structural similarity with Saccharomyces NPR2

(FlyBase, 1992-)

urea transport

inferred from sequence or structural similarity with Saccharomyces NPR2

(FlyBase, 1992-)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG9104 - CG4502

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Mintseris et al., 2009.11.23, Guruharsha et al., 2011)

CG9104 - Hsp23

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG9104 allele

Gene

References

External Data

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0030800

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0030800

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

32677

Orthologs

OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6WWS4B

Dipteran inclusive ortholog search

EOG6GHZXP

Insect inclusive ortholog search

EOG63R2H4

Arthropod inclusive ortholog search

EOG6FXPPZ

Metazoa inclusive ortholog search

EOG6W71PG

Orthologs in Drosophila Species (EOG6WWS4B)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21545

Drosophila persimilis

Dper\GL22789

Drosophila willistoni

Dwil\GK25826

Drosophila virilis

Dvir\GJ19452

Drosophila mojavensis

Dmoj\GI15348

Drosophila grimshawi

Dgri\GH11927

Orthologs in non-Drosophila Dipterans (EOG6GHZXP)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL015393

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003870

Anopheles gambiae

Malaria mosquito

Agam\AGAP000438

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ019912

Orthologs in non-Dipteran Insects (EOG63R2H4)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC409317

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG005242

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH13110

Atta cephalotes

Leafcutter ant

Acep\ACEP12288

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO21800

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL20173

Linepithema humile

Argentine ant

Lhum\LH13512

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB13240

Solenopsis invicta

Red fire ant

Sinv\SINV17136

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002211

Bombyx mori

Silkmoth

Bmor\BGIBMGA003860

Bombyx mori

Silkmoth

Bmor\BGIBMGA009882

Pediculus humanus

Human body louse

Phum\PHUM014780

Tribolium castaneum

Red flour beetle

Tcas\TC005889

Orthologs in non-Insect Arthropods (EOG6FXPPZ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_327841

Daphnia pulex

Water flea

Dpux\G3pdh

Ixodes scapularis

Deer tick

Isca\ISCW020276

Orthologs in non-Arthropod Metazoa (EOG6W71PG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\F49E8.1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_001479gn

Danio rerio

Zebrafish

Drer\nprl2

Xenopus tropicalis

Western clawed frog

Xtro\nprl2

Gallus gallus

Domestic chicken

Ggal\NPRL2

Mus musculus

House mouse

Mmus\Nprl2

Rattus norvegicus

Norway rat

Rnor\Nprl2

Homo sapiens

Human

Hsap\NPRL2

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\NPRL2

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21545

Drosophila persimilis

Dper\GL22789

Drosophila willistoni

Dwil\GK25826

Drosophila virilis

Dvir\GJ19452

Drosophila mojavensis

Dmoj\GI15348

Drosophila grimshawi

Dgri\GH11927

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

Bloomington

38896

y¹ sc^* v¹; P{TRiP.GL00667}attP2

VDRC

v10472

w¹¹¹⁸; P{GD4298}v10472

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 8 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD40282

Other clones

DPiM_LD40282

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0030800

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

32677

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

dsRNA has been made from templates generated with primers directed against this gene. RNAi of CG9104 disrupts the dendritic routing patterns of the ddaD and ddaE neurons, resulting in aberrantly oriented primary dendrites. RNAi also causes defects in dendrite morphogenesis.

(Parrish et al., 2006)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_132946

RefSeq (Proteins)

•

NP_573174

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

32677

UniProtKB/TrEMBL

•

Q9VXA0

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Nitrogen permease regulator 2 (IPR009348)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LD40282

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0030800

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0030800

DRSC - Results from RNAi screens.

•

FBgn0030800

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030800

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG9104-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0030800

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

32677

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

32677

modMine - Data generated by the modENCODE project.

•

FBgn0030800

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG9104

(Parrish et al., 2006, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1)

Name Synonym

Secondary FlyBase IDs

References ( 15 )

Research paper

Parrish et al., 2006, Genes Dev. 20(7): 820--835: Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. [FBrf0190556]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
Guruharsha et al., 2011, Cell 147(3):: Table S3. [FBrf0218395]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]

Personal communication to FlyBase

Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila.: A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project: DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

FlyBase analysis

FlyBase, 1992-, FlyBase curation.: FlyBase curation. [FBrf0105495]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]

Curated genome annotation

Yao, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126699]