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Gene Dmel\stas

General Information
Symbol	Dmel\stas	Species	D. melanogaster
Name	Stasimon	Annotation symbol	CG8408
Feature type	protein_coding_gene	FlyBase ID	FBgn0030850
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	16B9-16B9	Sequence location	X:17,517,254..17,521,928 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Stasimon is referred to in FlyBase by the symbol Dmel\stas (CG8408, FBgn0030850). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: positive regulation of synaptic transmission, cholinergic. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: SNARE associated Golgi protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult brain, adult Malpighian tubules, adult heart, adult salivary gland, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult fat body, larval salivary gland, inseminated spermatheca, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634053_at completely aligns to an exonic region of only a subset of 1 of the 2 FlyBase-annotated transcript isoforms of CG8408. Gene sequence location is X:17517247..17521929.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 16B9-16B9   Limits computationally determined from genome sequence between P{EP}bazEP1446 and P{EP}EP1464
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\stas for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) stas-RA FBtr0074487  NM_132997   1882   320 stas-RB FBtr0290036  NM_001144745   2163   174
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein stas-PA   FBpp0074261   35.8   320   9.31     NP_573225   AAF48742 stas-PB   FBpp0288475   19.7   174   8.61     NP_001138217   ACL82947
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • SNARE associated Golgi protein (IPR015414)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438513   AA438514   AA695631   AE014298 AAF48742   AE014298 ACL82947   AI542341   AI543523   AW942228   AY061150 AAL28698   BG636398   BG636812   BG636976   BI164215   BP544044   BP544045   BP545911   CO188923   CO191390   CO270647   CO272691   CO272886   CO277065   CO278531   CO279137   CO282645   CO283868   CO299827   CO313491   CO324692   CO339387   CO344615   EC061128   EC195373   EC195689   EC197333   EC201843   EC202687   EC209121   EC209271   EC210104   EC211644   EC234234   EC236001   EC236237   EC237022   EC243751   EC253655   EC257487   EV578498
UniProtKB/Swiss-Prot	Q9VX39
UniProtKB/TrEMBL	B7Z102
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult brain, adult Malpighian tubules, adult heart, adult salivary gland, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult fat body, larval salivary gland, inseminated spermatheca, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules    1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain  509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules  (1011.5) Adult Fat Body    463.2 Adult Salivary Gland  (674.2) Adult Heart  506.35 Adult VirginFemale Spermatheca  (779.9) Adult InseminatedFemale Spermatheca    411.6 Adult Ovary  (677.3) Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules  1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules    1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules    1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain  509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules  (1011.5) Adult Fat Body    463.2 Adult Salivary Gland  674.2 Adult Heart  506.35 Adult VirginFemale Spermatheca  779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary  677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules  1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    337.3 Larval Midgut    167 Larval Hindgut    395.5 Larval Malpighian Tubules    443.3 Larval Fat Body    125.1 Larval Salivary Gland    421.3 Larval Trachea    71.125 Larval Carcass    167.825 Adult Head    287.4 Adult Eye    208.5 Adult Brain    509.1 Adult Thoracic-Abdominal Ganglion    420.4 Adult Crop    270.7 Adult Midgut    276.5 Adult Hindgut    466.6 Adult Malpighian Tubules    1011.5 Adult Fat Body    463.2 Adult Salivary Gland    674.2 Adult Heart    506.35 Adult VirginFemale Spermatheca    779.9 Adult InseminatedFemale Spermatheca    411.6 Adult Ovary    677.3 Adult Testis    111.2 Adult Male Accessory Gland    418.8 Adult Carcass    280.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    287.4   NA  Eye    208.5   NA  Brain    509.1   337.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    420.4   NA  Crop    270.7   167  Midgut    276.5   395.5  Hindgut    466.6   443.3  Malpighian Tubules    1011.5   125.1  Fat Body    463.2   421.3  Salivary Gland    674.2   NA  Heart    506.35   71.125  Trachea    NA   NA  VirginFemale Spermatheca    779.9   NA  InseminatedFemale Spermatheca    411.6   NA  Ovary    677.3   NA  Testis    111.2   NA  Male Accessory Gland    418.8   167.825  Carcass    280.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (45) testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (45) testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    10 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    14 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    15 head, mated 4-day male    15 head, mated 20-day male    19 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    18 digestive system, larvae L3 wandering    16 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    13 fat body, larvae L3 wandering    2 fat body, white prepupae    7 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    12 carcass, 20-day adult    13 ovary, virgin 4-day female    54 ovary, mated 4-day female    45 testis, mated 4-day male    9 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (54) embryo 02-04hr    15 embryo 04-06hr  26 embryo 06-08hr  (27) embryo 08-10hr  (29) embryo 10-12hr  (27) embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr  (31) embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day  (34) adult female 05day  (43) adult female 30day  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (54) embryo 02-04hr    15 embryo 04-06hr  26 embryo 06-08hr  27 embryo 08-10hr  29 embryo 10-12hr  27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr  31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day  (34) adult female 05day  (43) adult female 30day  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    15 embryo 04-06hr    26 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    19 embryo 14-16hr    14 embryo 16-18hr    22 embryo 18-20hr    31 embryo 20-22hr    15 embryo 22-24hr    20 larva L1    18 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    18 white prepupae new    21 white prepupae 12hr    17 white prepupae 24hr    15 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    18 adult male 01day    18 adult male 05day    17 adult male 30day    19 adult female 01day    34 adult female 05day    43 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (27) Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2  (39) embryonic Kc167  (28) embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1  (34) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC  (38) ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2  (39) embryonic Kc167  28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1  (34) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC  (38) ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    24 embryonic 1182-4H    14 embryonic GM2    39 embryonic Kc167    28 embryonic S1    16 embryonic S3    22 leg disc CME L1    16 wing disc CME-W2    24 wing disc ML-DmD8    19 wing disc ML-DmD9    9 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    13 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    16 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    22 ovary fGS/OSS    21 ovary OSC    38 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (35) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  (33) Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (43) Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (35) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  (33) Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (43) Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    9 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    33 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • LD12309 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030850 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8408-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 stasGD3415 Other Phenotypes Allele neurophysiology defective | larval stage stasEY04008 neurophysiology defective | larval stage, with Scer\GAL4Cha.7.4 stasGD3415 neurophysiology defective | larval stage, with Scer\GAL4elav-C155 stasGD3415 Phenotype manifest in Allele embryonic/larval neuromuscular junction | larval stage stasEY04008 embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4elav-C155 stasGD3415
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of stas Class Mutagen Stocks Known lesion stasEY04008 P-element activity 1 -- stasMI07633 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of stas Class Mutagen Stocks Known lesion stasGD3415 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes stasGL01566 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes stasKK102040 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes stasScer\UAS.cLa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.GL01566} NA P{UAS-stas.L} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}stasEY04008 NA miscellaneous insertions Mi{MIC}stasMI07633 NA P{Switch2}GSG8892 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a cellular component or molecular function term for this gene. (Based on a review of available data on: 2008-03-20)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
positive regulation of synaptic transmission, cholinergic inferred from mutant phenotype (Lotti et al., 2012)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
stas - ATPsyn-γ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Aats-glupro anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Aats-ile anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Atpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG10306 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG11665 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG12264 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG1291 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG13220 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG1416 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG1444 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG1458 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG14715 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG1518 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG17593 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG2064 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG2065 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG31729 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG32138 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG34163 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG3523 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG4169 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG4729 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG4849 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG4972 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG7033 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG7878 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG8258 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CG9947 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CalpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Cand1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Cct5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Cctγ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Chc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Cpr anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Dhc64C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - EfTuM anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Fatp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Fs(2)Ket anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Gale anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Gnf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Gp210 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Jupiter anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Kap-α3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Karyβ3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Kr-h2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - LRP1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - MRP anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Mec2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Mi-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Mtpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Ost48 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - OstStt3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - OstΔ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Ostγ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Pdi anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Pp2A-29B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Psa anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rab1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Ranbp9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Ras85D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rop anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - RpS10b anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - RpS19a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpn1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpn9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpt1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpt4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Rpt5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - SF1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Sac1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Sc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Scamp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Sec61α anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Srp68 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Srp72 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - TER94 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Tcp-1ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Thiolase anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - Vap-33-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - abs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - alt anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - bor anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - cher anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - chic anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - eIF3-S8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - emb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - kst anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - l(1)G0230 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - larp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - mbo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - me31B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - msk anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - nop5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - pit anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - polo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - pont anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - ppan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - sqh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - α-Spec anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) stas - βCop anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions stas allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59063 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030850 DroID - A comprehensive database of gene and protein interactions. • FBgn0030850 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32737
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6V702Z Dipteran inclusive ortholog search EOG66Q72K Insect inclusive ortholog search EOG631ZV4 Arthropod inclusive ortholog search EOG6J0ZR5 Metazoa inclusive ortholog search EOG69KTJX
Orthologs in Drosophila Species (EOG6V702Z)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\stas     Drosophila simulans   Dsim\GD17353 Y   Drosophila sechellia   Dsec\GM13307 Y   Drosophila erecta   Dere\GG18175 Y   Drosophila yakuba   Dyak\GE15585 Y   Drosophila ananassae   Dana\GF22553 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21055 Y   Drosophila persimilis   Dper\GL20394 Y   Drosophila willistoni   Dwil\GK24991 Y   Drosophila virilis   Dvir\GJ19283 Y   Drosophila mojavensis   Dmoj\GI14632 Y   Drosophila grimshawi   Dgri\GH11899 Y
Orthologs in non-Drosophila Dipterans (EOG66Q72K)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014573   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009713   Anopheles gambiae Malaria mosquito  Agam\AGAP000769   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015793
Orthologs in non-Dipteran Insects (EOG631ZV4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC409411   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG009139   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10206   Atta cephalotes Leafcutter ant  Acep\ACEP20779   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16220   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22439   Linepithema humile Argentine ant  Lhum\LH23453   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25731   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000327   Pediculus humanus Human body louse  Phum\PHUM088060   Tribolium castaneum Red flour beetle  Tcas\GLEAN_08122
Orthologs in non-Insect Arthropods (EOG6J0ZR5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\GapCp   Ixodes scapularis Deer tick  Isca\ISCW015693
Orthologs in non-Arthropod Metazoa (EOG69KTJX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\tag-175   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006783gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006785gn   Danio rerio Zebrafish  Drer\tmem41b   Xenopus tropicalis Western clawed frog  Xtro\tmem41b   Gallus gallus Domestic chicken  Ggal\TMEM41B   Mus musculus House mouse  Mmus\Tmem41b   Rattus norvegicus Norway rat  Rnor\Tmem41b   Homo sapiens Human  Hsap\TMEM41B
Human Orthologs (1)
Gene OMIM HGNC Hsap\TMEM41B
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17353 Drosophila sechellia Dsec\GM13307 Drosophila erecta Dere\GG18175 Drosophila yakuba Dyak\GE15585 Drosophila ananassae Dana\GF22553 Drosophila pseudoobscura pseudoobscura Dpse\GA21055 Drosophila persimilis Dper\GL20394 Drosophila willistoni Dwil\GK24991 Drosophila virilis Dvir\GJ19283 Drosophila mojavensis Dmoj\GI14632 Drosophila grimshawi Dgri\GH11899
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	43846 y1 w* Mi{MIC}stasMI07633 15704 y1 w67c23 P{EPgy2}stasEY04008 43221 y1 sc* v1; P{TRiP.GL01566}attP40
VDRC	v11574 w1118; P{GD3415}v11574 v12432 w1118; P{GD3415}v12432
Genomic Clones ( 1 )
	BACR42I14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 45 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD12309
Other clones	DPiM_LD12309
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM03152 LD12310 RE03843 SD08630 SD10314 SD14096 SD14818
Other clones	1786 8983 9367 17660 19088 50930 59064 77766 80945 82303 105086 106989 214245.41 214441.38 CK01.52B.E11 CK01.65B.D10 CK01.128C.H1 Dmel_dig_001229_0665_3717 EC30796 EK042418 EK099629 EK108050 EK108650 EK122828 EK130310 EK133618 EK160909 EK164705 EK176710 EK194530 EK233059 EP01907 EP19613 FGC023G07 FGH001H01 SD14605
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030850 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32737
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132997 NM_001144745 RefSeq (Proteins) • NP_573225 NP_001138217 DDBJ / EMBL / GenBank • AA438513 AAF48742 AAL28698 ACL82947 AW942228 AY061150 Entrez Gene - A searchable database of RefSeq genes. • 32737 UniProtKB/Swiss-Prot • Q9VX39 UniProtKB/TrEMBL • B7Z102
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • SNARE associated Golgi protein (IPR015414) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD12309
Linkouts
	BioGRID - A database of protein and genetic interactions • 59063 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030850 DroID - A comprehensive database of gene and protein interactions. • FBgn0030850 DRSC - Results from RNAi screens. • FBgn0030850 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030850 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8408-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030850 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32737 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32737 modMine - Data generated by the modENCODE project. • FBgn0030850
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG8408 (Ni et al., 2010.12.1, Cole et al., 2012.7.6, Lotti et al., 2012, Praveen et al., 2012, Nicholson et al., 2008, Lin et al., 2010, Gruber and Long, 2009, Pessa et al., 2010, Keleman et al., 2009.8.5) stas (Lotti et al., 2012) Tmem41b (Lotti et al., 2012)
Name Synonym	Stasimon (Lotti et al., 2012, ) stasimon (Lotti et al., 2012) stymied in smn (Lotti et al., 2012)
Secondary FlyBase IDs
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 8 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) Website  ( 1 )
Recent research papers ( 2 )
	Lotti et al., 2012, Cell 151(2): 440--454 An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. [FBrf0219670] Praveen et al., 2012, Cell Rep. 1(6): 624--631 A Drosophila Model of Spinal Muscular Atrophy Uncouples snRNP Biogenesis Functions of Survival Motor Neuron from Locomotion and Viability Defects. [FBrf0218971] Show all research papers ...