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Gene Dmel\CG5800

General Information
Symbol	Dmel\CG5800	Species	D. melanogaster
Name		Annotation symbol	CG5800
Feature type	protein_coding_gene	FlyBase ID	FBgn0030855
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	16B10-16B10	Sequence location	X:17,530,314..17,533,036 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5800 (FBgn0030855). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: RNA helicase activity. There is experimental evidence that it is involved in the biological process: larval somatic muscle development; neurogenesis. 4 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval somatic muscle. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Domain of unknown function DUF4217; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1624138_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5800. Gene sequence location is X:17530314..17533036.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 16B10-16B10   Limits computationally determined from genome sequence between P{EP}bazEP1446 and P{EP}EP1464
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5800 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5800-RA FBtr0074453  NM_133002   2647   826
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5800-PA   FBpp0074227   92.8   826   6.80     NP_573230   AAF48747
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF4217 (IPR025313) RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) P-loop containing nucleoside triphosphate hydrolase (IPR027417) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201101   AA246501   AA264201   AA391107   AA941859   AE014298 AAF48747   AI293987   AI513162   AI530834   AI532032   AY119628 AAM50282   BF499302   BI170864   BI214123   BI216827   BI232810   BI234459   BI237174   BI237481   BI237946   BI239474   BI240643   BI356160   BI357540   BI357615   BI362107   BI577903   BP546483   CK658177   CK662483   CO276628   CO282517   CO287297   CO342972   EC052096   EC052589   EC053562   EC054543   EC055778   EC055927   EC056228   EC245444   EC256115   GH747943   GH752605   GH752997   GH756308   GH757246   GH758240   GH758466   GH774311   GH776475   GH777036   GH777436   GH778676   GH780478   GH781649   GH781809   GH785283   GH788238   GH790345   GH791869   GH792156   GH792968   GH794881   GH795523   GH801512   GH801603   GH804307   GH806051   GH808298   GH811249   GH812235   GH816728   GH817182   GH818322   GH818462   GH820340   GH822902   GH823057   GH823297   GH824077   GH825781   GH827824   GH831474   GH831573   GH831664   GH833672   GH834891   GH835399   GH836658   GH836902   GH837371   GH840251   GH840483   GH841390   GH841461   GH843429   GH845145   GH846599   GH847539   GH847928   GH848831   GH850277   GH856405   GH858645   GH861250   GH862330   GH862356   GH865665   GH871226   GH872941   GH877142   GH877794   GH878384   GH889779   GH897672   GH898872   GH900050   GH903971   GH904891   GH905837   GH906306   GH907799   GH908971   GH914675   GH914819   GH915091   GH915484   GH919022   GH920203   GH920982   GH921343   GH921591   GH921866   GH922742   GH923360   GH927494   GH929360   GH929361   GH933164   GH934224   GH940599
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VX34
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   hindgut anlage   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) inclusive hindgut primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic/larval lymph gland   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    96.3 Larval Midgut    19 Larval Hindgut    48 Larval Malpighian Tubules    17.1 Larval Fat Body    11 Larval Salivary Gland    89 Larval Trachea    65.75 Larval Carcass    61.825 Adult Head    24.7 Adult Eye    17.275 Adult Brain    19.4 Adult Thoracic-Abdominal Ganglion    18.3 Adult Crop    36.3 Adult Midgut    21 Adult Hindgut    19.5 Adult Malpighian Tubules    23.3 Adult Fat Body    40.7 Adult Salivary Gland    43 Adult Heart    20.275 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    44.5 Adult Ovary    173.2 Adult Testis    13.8 Adult Male Accessory Gland    79.3 Adult Carcass    26.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    24.7   NA  Eye    17.275   NA  Brain    19.4   96.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    18.3   NA  Crop    36.3   no informative data  Midgut    no informative data   48  Hindgut    19.5   17.1  Malpighian Tubules    no informative data   no informative data  Fat Body    40.7   89  Salivary Gland    43   NA  Heart    20.275   65.75  Trachea    NA   NA  VirginFemale Spermatheca    37.3   NA  InseminatedFemale Spermatheca    44.5   NA  Ovary    173.2   NA  Testis    no informative data   NA  Male Accessory Gland    79.3   61.825  Carcass    26.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female  (62) ovary, mated 4-day female  (73) testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female  (62) ovary, mated 4-day female  (73) testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    5 head, virgin 4-day female    8 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    13 head, mated 20-day female    4 head, mated 1-day male    5 head, mated 4-day male    7 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    11 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    2 carcass, larvae L3 wandering    15 carcass, 1-day adult    6 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    62 ovary, mated 4-day female    73 testis, mated 4-day male    11 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr  (48) embryo 04-06hr  (44) embryo 06-08hr  (39) embryo 08-10hr  (36) embryo 10-12hr  (27) embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1  26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day  (29) adult female 30day  (30) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr  (48) embryo 04-06hr  (44) embryo 06-08hr  (39) embryo 08-10hr  (36) embryo 10-12hr  27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1  26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day  29 adult female 30day  30 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    48 embryo 04-06hr    44 embryo 06-08hr    39 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    22 embryo 22-24hr    18 larva L1    26 larva L2    14 larva L3 12hr old    9 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    7 pupae 2d postWPP    5 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    4 adult female 01day    18 adult female 05day    29 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167    123 embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (55) Schneider line 2 Sg4  (44) embryonic 1182-4H  (49) embryonic GM2  (33) embryonic Kc167  (123) embryonic S1  (31) embryonic S3  (30) leg disc CME L1  (63) wing disc CME-W2  (34) wing disc ML-DmD8  (28) wing disc ML-DmD9  (41) wing disc ML-DmD16-c3  (66) wing disc ML-DmD21  (70) wing disc ML-DmD32  (30) haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11  (46) antennal disc ML-DmD20-c5  (31) mixed discs ML-DmD4-c1  (44) CNS ML-DmBG1-c1  (58) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    20 ovary fGS/OSS  (59) ovary OSC  (52) ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167  (123) embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167    123 embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167    123 embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (55) Schneider line 2 Sg4  (44) embryonic 1182-4H  (49) embryonic GM2  (33) embryonic Kc167  (123) embryonic S1  31 embryonic S3  30 leg disc CME L1  (63) wing disc CME-W2  (34) wing disc ML-DmD8  28 wing disc ML-DmD9  (41) wing disc ML-DmD16-c3  (66) wing disc ML-DmD21  (70) wing disc ML-DmD32  30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11  (46) antennal disc ML-DmD20-c5  31 mixed discs ML-DmD4-c1  (44) CNS ML-DmBG1-c1  (58) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    20 ovary fGS/OSS  (59) ovary OSC  (52) ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167  123 embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    55 Schneider line 2 Sg4    44 embryonic 1182-4H    49 embryonic GM2    33 embryonic Kc167    123 embryonic S1    31 embryonic S3    30 leg disc CME L1    63 wing disc CME-W2    34 wing disc ML-DmD8    28 wing disc ML-DmD9    41 wing disc ML-DmD16-c3    66 wing disc ML-DmD21    70 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    46 antennal disc ML-DmD20-c5    31 mixed discs ML-DmD4-c1    44 CNS ML-DmBG1-c1    58 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    20 ovary fGS/OSS    59 ovary OSC    52 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult  (50) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (33) Paraquat 10 mM 48 hrs, 4-day adult  (30) Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult  (50) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (33) Paraquat 10 mM 48 hrs, 4-day adult  30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    14 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_08 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	BDGP expression data • RE19835 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030855 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5800-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG5800 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal CG5800GD11773 lethal, with Scer\GAL4Act5C.PU CG5800KK102565 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG5800GD11773 Other Phenotypes Allele neuroanatomy defective | larval stage CG5800GD11773 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage CG5800GD11773 embryonic/larval somatic muscle, with Scer\GAL4Mef2.PR CG5800GD11773 ganglion mother cell | larval stage CG5800GD11773
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG5800 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5800 Class Mutagen Stocks Known lesion CG5800GD11773 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5800GL01551 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5800KK102565 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5800NIG.5800R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11773} NA P{KK102565} NA P{NIG.5800R} NA P{TRiP.GL01551} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
larval somatic muscle development inferred from mutant phenotype (Schnorrer et al., 2010) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent helicase activity inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR011545 (FlyBase Curators et al., 2004-) nucleic acid binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) RNA helicase activity inferred from sequence or structural similarity with Saccharomyces HCA4 (Lasko, 2000)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG5800 - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5800 - Rrp46 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5800 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5800 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030855 DroID - A comprehensive database of gene and protein interactions. • FBgn0030855 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32742
Orthologs
OrthoDB Orthologs (39) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69GM23 Dipteran inclusive ortholog search EOG6WWRSN Insect inclusive ortholog search EOG6K0PHK Arthropod inclusive ortholog search EOG6WSTRQ Metazoa inclusive ortholog search EOG6V1KSZ
Orthologs in Drosophila Species (EOG69GM23)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5800     Drosophila simulans   Dsim\GD15676 Y   Drosophila sechellia   Dsec\GM13518 Y   Drosophila erecta   Dere\GG19124 Y   Drosophila yakuba   Dyak\GE17675 Y   Drosophila ananassae   Dana\GF19542 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19139 Y   Drosophila persimilis   Dper\GL15986 Y   Drosophila willistoni   Dwil\GK16405 Y   Drosophila virilis   Dvir\GJ15571     Drosophila virilis   Dvir\GJ15570 Y   Drosophila mojavensis   Dmoj\GI21709 Y   Drosophila grimshawi   Dgri\GH24149 Y
Orthologs in non-Drosophila Dipterans (EOG6WWRSN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013400   Anopheles gambiae Malaria mosquito  Agam\AGAP001057   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006244
Orthologs in non-Dipteran Insects (EOG6K0PHK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB52057   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012875   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20468   Atta cephalotes Leafcutter ant  Acep\ACEP17668   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23486   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13226   Linepithema humile Argentine ant  Lhum\LH14083   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21473   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001434   Bombyx mori Silkmoth  Bmor\BGIBMGA011264   Pediculus humanus Human body louse  Phum\PHUM490520   Tribolium castaneum Red flour beetle  Tcas\Ddx10
Orthologs in non-Insect Arthropods (EOG6WSTRQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_223010   Ixodes scapularis Deer tick  Isca\ISCW008472
Orthologs in non-Arthropod Metazoa (EOG6V1KSZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y23H5B.6   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013786gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008600gn   Danio rerio Zebrafish  Drer\ddx10   Xenopus tropicalis Western clawed frog  Xtro\ddx10   Gallus gallus Domestic chicken  Ggal\DDX10   Mus musculus House mouse  Mmus\Ddx10   Rattus norvegicus Norway rat  Rnor\Ddx10   Homo sapiens Human  Hsap\DDX10
Human Orthologs (1)
Gene OMIM HGNC Hsap\DDX10
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15676 Drosophila sechellia Dsec\GM13518 Drosophila erecta Dere\GG19124 Drosophila yakuba Dyak\GE17675 Drosophila ananassae Dana\GF19542 Drosophila pseudoobscura pseudoobscura Dpse\GA19139 Drosophila persimilis Dper\GL15986 Drosophila willistoni Dwil\GK16405 Drosophila virilis Dvir\GJ15570 Drosophila mojavensis Dmoj\GI21709 Drosophila grimshawi Dgri\GH24149
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	43206 y1 sc* v1; P{TRiP.GL01551}attP40
VDRC	v103769 P{KK102565}VIE-260B v27519 w1118; P{GD11773}v27519
Genomic Clones ( 1 )
	BACR42I14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 142 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE19835
Other clones	DPiM_RE19835
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT13833 LD03675 LD05424 LD07816 LD10038 LD27170 LD45357 LP07263 LP14903 LP22739 RE12465 RE24109 RE28933 RE30158 RE33350 RE33716 RE34284 RE35962 RE37533 RE42238 RE44054 RE44146 RE46580 RE71667 SD01565 SD03379
Other clones	44906 214211.39 EC052096 EC052589 EC053562 EC054543 EC055778 EC055927 EC056228 EK065506 EK121706 EK160637 EP15841 FGH106H07 RP003017989 RP003023119 RP003058030 RP003072708 RP003092921 RP003102021 RP003106812 RP003110402 RP003110776 RP003113119 RP003115583 RP003130886 RP003131262 RP003142422 RP003146746 RP003159604 RP003164875 RP003169670 RP003176897 RP003186351 RP003189355 RP003193405 RP003198373 RP003201003 RP003203851 RP003204715 RP003211861 RP003222656 RP003229286 RP003233266 RP003233446 RP003234822 RP003249710 RP003250086 RP003267032 RP003267573 RP003268946 RP003272432 RP003273709 RP003275064 RP003275430 RP003278958 RP003291334 RP003294157 RP003298105 RP003298471 RP003302056 RP003305720 RP003307336 RP003309211 RP003309231 RP003312985 RP003315290 RP003320483 RP003331068 RP003333203 RP003338676 RP003354706 RP003359672 RP003377850 RP003378463 RP003382548 RP003385557 RP003397409 RP003417532 RP003425371 RP003438747 RP003442189 RP003442197 RP003446550 RP003462285 RP003475395 RP003475581 RP003476407 RP003481092 RP003502836 RP003503655 RP003506538 RP003506608 RP003513620 RP003524579 RP003529832 RP003531553 RP003547884 RP003548810 RP003549128 RP003554516 RP003569324 RP003578353 RP003590294 RP003595356 RP003635079 RP003645013 RP003645673 RP003649913 RP003651052 RP003652338 RP003658344 RP003670518 RP003677714
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030855 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32742
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Expression is enriched in embryonic gonads. (Shigenobu et al., 2006)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_133002 RefSeq (Proteins) • NP_573230 DDBJ / EMBL / GenBank • AAF48747 AAM50282 AY119628 BI214123 Entrez Gene - A searchable database of RefSeq genes. • 32742 UniProtKB/TrEMBL • Q9VX34
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF4217 (IPR025313) RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) P-loop containing nucleoside triphosphate hydrolase (IPR027417) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE19835
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030855 DroID - A comprehensive database of gene and protein interactions. • FBgn0030855 DRSC - Results from RNAi screens. • FBgn0030855 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030855 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5800-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030855 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32742 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32742 modMine - Data generated by the modENCODE project. • FBgn0030855
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	cg5800 (Lasko, 2000) CG5800 (Shigenobu et al., 2006, Butchar et al., 2012, Keleman et al., 2009.8.5, Schnorrer et al., 2010, Neumüller et al., 2011, Ni et al., 2010.12.1, Japanese National Institute of Genetics, 2012.5.21) DmRH14 (Boudet et al., 2001)
Name Synonym
Secondary FlyBase IDs
References ( 22 )
Generate a list of	All references relating to this gene ( 22 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 2 )
	Butchar et al., 2012, Genetics 191(4): 1213--1226 New negative feedback regulators of egfr signaling in Drosophila. [FBrf0219175] Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Show all research papers ...