A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\CG6617

General Information
SymbolDmel\CG6617SpeciesD. melanogaster
NameAnnotation symbolCG6617
Feature typeprotein_coding_geneFlyBase IDFBgn0030944
Gene Model StatusCurrent Stock availability 2 publicly available
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map17C7-17C7Sequence locationX:18,543,429..18,544,479 [-]

Genomic Maps

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modENCODE GBrowse
detailed view
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Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol Dmel\CG6617 (FBgn0030944). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: CTLH, C-terminal LisH motif; LisH dimerisation motif; LisH dimerisation motif, subgroup; Ran binding protein, CRA domain; Ran binding protein-like, CRA domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632736_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6617. Gene sequence location is X:18543429..18544479.

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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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atom feed
FB2011_10
FB2012_01
Sequence features
HFA20001
BKN28439
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
17C7-17C7  
Limits computationally determined from genome sequence between P{EP}EP443EP443&P{EP}BxEP1383 and P{EP}Pk17EEP438  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG6617 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0301545 FBtr0074616 FBtr0074601 FBtr0074615 FBtr0074614 FBpp0074372 FBpp0074386 FBpp0074385 FBti0013322 FBti0053939 FBti0013233 FBti0013217 FBti0071210 FBti0018412 FBti0100044 FBti0109430 FBti0048784 FBti0075604
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG6617-RA
FBtr0074615
 NM_133087
  991
  225
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG6617-PA  
FBpp0074386  
26.0  
225  
4.64  
  NP_573315
  AAF48867
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
LisH dimerisation motif (IPR006594)
CTLH, C-terminal LisH motif (IPR006595)
Ran binding protein-like, CRA domain (IPR013144)
LisH dimerisation motif, subgroup (IPR013720)
Ran binding protein, CRA domain (IPR019589)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA202103
 
AA391019
 
AA820841
 
AA821061
 
AA941241
 
AE014298
AAF48867
 
AF171830
 
AI259564
 
AI405518
 
AI514029
 
AW942724
 
AY095034
AAM11362
 
BI215680
 
BI228298
 
BI236363
 
BI605698
 
BP557194
 
BP557195
 
CO270142
 
CO312617
 
EC052871
 
EC087932
 
EC088981
 
EL872786
 
EL872787
 
EV595979
 
EV597225
 
EV599564
 
FD585683
 
FD585686
 
FD585692
 
FD585704
 
FD586020
 
FD587416
 
GH739759
 
GH740257
 
GH741860
 
GH742586
 
GH744769
 
GH745378
 
GH765469
 
GH765916
 
GH766174
 
GH767112
 
GH768109
 
GH768573
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG6540-RA CG6617-RA Ing3-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
(The modENCODE Consortium, 2010)
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
•
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
•
FlyExpress - Embryonic expression images (BDGP data)
•
Show all FlyExpress processed images for CG6617
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Phenotype manifest in
Allele
hide Classical Alleles ( 1 )
For All Classical Alleles Show

Allele of CG6617ClassMutagenStocksKnown lesion
CG6617MB02683
1 --
hide Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show

Allele of CG6617ClassMutagenStocksKnown lesion
CG6617KK1084391 Yes
CG6617GD119810 Yes
hide Aneuploid Aberrations
Disrupted in
(Ryder, 2004.4.26)
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
P{GD11981}
NA
P{KK108439}
NA
Insertions
Type of insertions
Name
Expression data
insertion of enhancer trap binary system
Mi{ET1}CG6617MB02683
No
hide Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
hide Terms Based on Experimental Evidence ( 0 terms )
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
nuclear_gene
 
protein_coding_gene
 
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
CG6617 allele
Gene
References
hide External Data
Linkouts
BioGRID - A database of protein and genetic interactions
•
DPiM - DPiM, Drosophila Protein interaction Map
•
DroID - A comprehensive database of gene and protein interactions.
•
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
•
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
 
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
•
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
•
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 2 )
Bloomington
23464
w1118 Mi{ET1}CG6617MB02683 CG6540MB02683
VDRC
v105737
P{KK108439}VIE-260B
hide Genomic Clones ( 1 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 42 )

Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
•
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
hide Antibody Information
hide Other Information
hide Discoverer
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Source for merge of: CG6617 anon-EST:Posey180
(Bayraktaroglu, 2000.11.2)
Additional comments
hide Other Comments
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
•
RefSeq (Proteins)
•
DDBJ / EMBL / GenBank
•
Entrez Gene - A searchable database of RefSeq genes.
•
UniProtKB/TrEMBL
•
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
LisH dimerisation motif (IPR006594)
CTLH, C-terminal LisH motif (IPR006595)
Ran binding protein-like, CRA domain (IPR013144)
LisH dimerisation motif, subgroup (IPR013720)
Ran binding protein, CRA domain (IPR019589)
Linkouts
BioGRID - A database of protein and genetic interactions
•
DPiM - DPiM, Drosophila Protein interaction Map
•
DroID - A comprehensive database of gene and protein interactions.
•
DRSC - Results from RNAi screens.
•
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
•
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
•
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
•
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
InParanoid A subset of ortholog calls from InParanoid.
•
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
•
modMine - Data generated by the modENCODE project.
•
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
•
hide Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym
anon-EST:Posey180
 
CG6617
(Przewloka et al., 2007, Keleman et al., 2009.8.5, Bandyopadhyay et al., 2006)
Name Synonym
Secondary FlyBase IDs
  • FBgn0027737
hide References ( 12 )
Research paper
Przewloka et al., 2007, PLoS ONE 2(5): e478
Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster. [FBrf0200394]
Bandyopadhyay et al., 2006, Genome Res. 16(3): 428--435
Systematic identification of functional orthologs based on protein network comparison. [FBrf0190794]
Kanda et al., 2002, J. Biol. Chem. 277(32): 28372--28375
Wengen, a Member of the Drosophila Tumor Necrosis Factor Receptor Superfamily, Is Required for Eiger Signaling. [FBrf0151360]
Supplementary material
The modENCODE Consortium, 2010, Science 330(6012):
DataS14: Gene co-expression clusters. [FBrf0213979]
Dietzl et al., 2007, Nature 448(7150):
Supplementary Table 1. [FBrf0202579]
Giot et al., 2003, Science 302(5651):
Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Bellen, 2007.4.5, batch731.xml
batch731.xml [FBrf0191801]
Ryder, 2004.4.26, Exelixis CG deletion data.
Exelixis CG deletion data. [FBrf0184335]
Bayraktaroglu, 2000.11.2, Current list of possibly CG-able known genes.
Current list of possibly CG-able known genes. [FBrf0131225]
Computer file
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0125078]