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Gene Dmel\CG7358

General Information
Symbol	Dmel\CG7358	Species	D. melanogaster
Name		Annotation symbol	CG7358
Feature type	protein_coding_gene	FlyBase ID	FBgn0030974
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	17F2-17F2	Sequence location	X:18,783,011..18,787,669 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7358 (FBgn0030974). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630000_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG7358. Gene sequence location is X:18783043..18787666.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Polypeptides CG7358-PB CG7358-PC Transcripts CG7358-RC CG7358-RB
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 17F2-17F2   Limits computationally determined from genome sequence between P{EP}CG7326EP1133 and P{EP}CG7502EP1326
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7358 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7358-RA FBtr0074652  NM_133111   3952   1150 CG7358-RB FBtr0342879     3919   1139 CG7358-RC FBtr0342880     4147   842
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7358-PA   FBpp0074423   129.0   1150   9.74     NP_573339   AAF48904 CG7358-PB   FBpp0309680   127.8   1139   9.69       CG7358-PC   FBpp0309681   95.3   842   10.84
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201339   AA391620   AA438451   AA438661   AA540332   AA540929   AA950024   AA950907   AA979136   AE014298 AAF48904   AI238702   AI534956   AI543210   AW941801   AY128424 AAM75017   BG638029   BI165614   BI173896   BI212291   BI238017   BI242817   BI362677   BI366892   BI367913   BI481695   BI568372   CO308450   CO308459   CO338004   EC066249   EC249579   EC261621   EV583958
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VWN4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   anterior endoderm anlage   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   central brain primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    165.7 Larval Midgut    102 Larval Hindgut    97.7 Larval Malpighian Tubules    109.3 Larval Fat Body    65.2 Larval Salivary Gland    229 Larval Trachea    121 Larval Carcass    93.1 Adult Head    104 Adult Eye    140.25 Adult Brain    255.9 Adult Thoracic-Abdominal Ganglion    206.2 Adult Crop    102.1 Adult Midgut    81.3 Adult Hindgut    86 Adult Malpighian Tubules    104.7 Adult Fat Body    62.8 Adult Salivary Gland    298.7 Adult Heart    75.8 Adult VirginFemale Spermatheca    89.6 Adult InseminatedFemale Spermatheca    108.6 Adult Ovary    107.4 Adult Testis    43 Adult Male Accessory Gland    142.1 Adult Carcass    101.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    104   NA  Eye    140.25   NA  Brain    255.9   165.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    206.2   NA  Crop    102.1   102  Midgut    81.3   97.7  Hindgut    86   109.3  Malpighian Tubules    104.7   65.2  Fat Body    62.8   229  Salivary Gland    298.7   NA  Heart    75.8   121  Trachea    NA   NA  VirginFemale Spermatheca    89.6   NA  InseminatedFemale Spermatheca    108.6   NA  Ovary    107.4   NA  Testis    43   NA  Male Accessory Gland    142.1   93.1  Carcass    101.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (30) central nervous system, larvae L3  (44) central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male  (27) head, mated 4-day male  (27) head, mated 20-day male  (29) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering  (29) carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female  (28) ovary, mated 4-day female  (28) testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  30 central nervous system, larvae L3  (44) central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male  27 head, mated 4-day male  27 head, mated 20-day male  29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering  29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female  28 ovary, mated 4-day female  28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    44 central nervous system, pupae P8    23 head, virgin 1-day female    15 head, virgin 4-day female    18 head, virgin 20-day female    16 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    15 head, mated 1-day male    27 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    9 fat body, white prepupae    11 fat body, pupae P8    18 carcass, larvae L3 wandering    29 carcass, 1-day adult    13 carcass, 4-day adult    14 carcass, 20-day adult    13 ovary, virgin 4-day female    28 ovary, mated 4-day female    28 testis, mated 4-day male    6 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    146 embryo 04-06hr    123 embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (52) embryo 02-04hr  (146) embryo 04-06hr  (123) embryo 06-08hr  (79) embryo 08-10hr  (59) embryo 10-12hr  (55) embryo 12-14hr  (31) embryo 14-16hr  (42) embryo 16-18hr  26 embryo 18-20hr    24 embryo 20-22hr  (31) embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr  (36) pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day  (27) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr  (146) embryo 04-06hr  (123) embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    146 embryo 04-06hr    123 embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    146 embryo 04-06hr    123 embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (52) embryo 02-04hr  (146) embryo 04-06hr  (123) embryo 06-08hr  (79) embryo 08-10hr  (59) embryo 10-12hr  (55) embryo 12-14hr  31 embryo 14-16hr  (42) embryo 16-18hr  26 embryo 18-20hr    24 embryo 20-22hr  31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr  (36) pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day  27 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr  (146) embryo 04-06hr  123 embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    146 embryo 04-06hr    123 embryo 06-08hr    79 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    31 embryo 14-16hr    42 embryo 16-18hr    26 embryo 18-20hr    24 embryo 20-22hr    31 embryo 22-24hr    21 larva L1    17 larva L2    15 larva L3 12hr old    13 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    25 white prepupae 24hr    36 pupae 2d postWPP    20 pupae 3d postWPP    11 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    17 adult male 30day    16 adult female 01day    22 adult female 05day    25 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4  (40) embryonic 1182-4H  (46) embryonic GM2    24 embryonic Kc167  (27) embryonic S1  (29) embryonic S3    22 leg disc CME L1  (37) wing disc CME-W2    12 wing disc ML-DmD8  (27) wing disc ML-DmD9  (42) wing disc ML-DmD16-c3  (43) wing disc ML-DmD21  (47) wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11  (27) antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1  (30) CNS ML-DmBG1-c1  (27) CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS  (36) ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4  (40) embryonic 1182-4H  (46) embryonic GM2    24 embryonic Kc167  27 embryonic S1  29 embryonic S3    22 leg disc CME L1  (37) wing disc CME-W2    12 wing disc ML-DmD8  27 wing disc ML-DmD9  (42) wing disc ML-DmD16-c3  (43) wing disc ML-DmD21  (47) wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11  27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1  30 CNS ML-DmBG1-c1  27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS  (36) ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    40 embryonic 1182-4H    46 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    22 leg disc CME L1    37 wing disc CME-W2    12 wing disc ML-DmD8    27 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    47 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    22 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    18 tumorous blood cells mbn2    14 ovary fGS/OSS    36 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult  (27) Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  (27) Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult  27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    19 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    19 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_17 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • GH14795 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030974 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7358-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG7358 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG7358GD12212 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG7358GD12212 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG7358GD12212
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG7358 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7358 Class Mutagen Stocks Known lesion CG7358GD12212 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG7358KK105583 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel7465 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12212} NA P{KK105583} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}EY04219 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG7358 - CG15784 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - CG16789 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - CG2938 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - CG8545 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - CkIIβ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - Hakai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - Saf-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - eIF4AIII anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - fl(2)d anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG7358 - nito anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG7358 - sqh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7358 - vir anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7358 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030974 DroID - A comprehensive database of gene and protein interactions. • FBgn0030974 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32886
Orthologs
OrthoDB Orthologs (47) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6R24F2 Dipteran inclusive ortholog search EOG6ZPF45 Insect inclusive ortholog search EOG6GMSSW Arthropod inclusive ortholog search EOG6M37RD Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6R24F2)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG7358     Drosophila sechellia   Dsec\GM22778 Y   Drosophila yakuba   Dyak\GE15483 Y   Drosophila willistoni   Dwil\GK25102 Y   Drosophila virilis   Dvir\GJ19270 Y   Drosophila mojavensis   Dmoj\GI15512 Y   Drosophila grimshawi   Dgri\GH24454 Y
Orthologs in non-Drosophila Dipterans (EOG6ZPF45)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004702
Orthologs in non-Dipteran Insects (EOG6GMSSW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB49296   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003808   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007332   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12264   Atta cephalotes Leafcutter ant  Acep\ACEP24963   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15257   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22861   Linepithema humile Argentine ant  Lhum\LH21235   Pogonomyrmex barbatus Red harvester ant  Pbar\PB27166   Solenopsis invicta Red fire ant  Sinv\SINV22466   Acyrthosiphon pisum Pea aphid  Apim\ACYPI28639   Acyrthosiphon pisum Pea aphid  Apim\ACYPI081266   Acyrthosiphon pisum Pea aphid  Apim\ACYPI087069   Acyrthosiphon pisum Pea aphid  Apim\ACYPI069183   Acyrthosiphon pisum Pea aphid  Apim\ACYPI082894   Acyrthosiphon pisum Pea aphid  Apim\ACYPI083473   Acyrthosiphon pisum Pea aphid  Apim\ACYPI086614   Acyrthosiphon pisum Pea aphid  Apim\ACYPI062038   Acyrthosiphon pisum Pea aphid  Apim\ACYPI082185   Acyrthosiphon pisum Pea aphid  Apim\ACYPI070798   Acyrthosiphon pisum Pea aphid  Apim\ACYPI48850   Acyrthosiphon pisum Pea aphid  Apim\ACYPI068758   Acyrthosiphon pisum Pea aphid  Apim\ACYPI087331   Acyrthosiphon pisum Pea aphid  Apim\ACYPI38869   Acyrthosiphon pisum Pea aphid  Apim\ACYPI080090   Acyrthosiphon pisum Pea aphid  Apim\ACYPI083305   Acyrthosiphon pisum Pea aphid  Apim\ACYPI080210   Acyrthosiphon pisum Pea aphid  Apim\ACYPI081155   Acyrthosiphon pisum Pea aphid  Apim\ACYPI084347   Acyrthosiphon pisum Pea aphid  Apim\ACYPI069798   Acyrthosiphon pisum Pea aphid  Apim\ACYPI080520   Acyrthosiphon pisum Pea aphid  Apim\ACYPI089153   Acyrthosiphon pisum Pea aphid  Apim\ACYPI082597   Bombyx mori Silkmoth  Bmor\BGIBMGA003023   Pediculus humanus Human body louse  Phum\PHUM137500   Tribolium castaneum Red flour beetle  Tcas\TC014015
Orthologs in non-Insect Arthropods (EOG6M37RD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\ndhF   Daphnia pulex Water flea  Dpux\JGI_V11_322523   Ixodes scapularis Deer tick  Isca\ISCW021985
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM22778 Drosophila erecta Dere\GG18086 Drosophila yakuba Dyak\GE15483 Drosophila ananassae Dana\GF19051 Drosophila pseudoobscura pseudoobscura Dpse\GA20292 Drosophila persimilis Dper\GL21334 Drosophila willistoni Dwil\GK25102 Drosophila virilis Dvir\GJ19270 Drosophila mojavensis Dmoj\GI15512 Drosophila grimshawi Dgri\GH24454
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v35209 w1118; P{GD12212}v35209 v35212 w1118; P{GD12212}v35212
Genomic Clones ( 1 )
	BACR25O02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 30 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH14795
Other clones	DPiM_GH14795
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD04322 LD10669 LD12555 LD19789 LD20122 LD29967 LD31070 LD33411 RE05543 RE17029 RE17352 RE34373 RE40251 RE47296 RE52529 RE53785 RE64288 RH39807 SD01253 SD09907
Other clones	154442 154772 569862 Dmel_dig_010635_0665_3699 EK258214 EK258246 EN15748 LD12981
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030974 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32886
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_133111 RefSeq (Proteins) • NP_573339 DDBJ / EMBL / GenBank • AAF48904 AAM75017 AI238702 AW941801 AY128424 Entrez Gene - A searchable database of RefSeq genes. • 32886 UniProtKB/TrEMBL • Q9VWN4
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH14795
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030974 DroID - A comprehensive database of gene and protein interactions. • FBgn0030974 DRSC - Results from RNAi screens. • FBgn0030974 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030974 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7358-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030974 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32886 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32886 modMine - Data generated by the modENCODE project. • FBgn0030974
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG7358 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Gonzalez et al., 2002, Genetics 161(3): 1137--1154 Chromosomal elements evolve at different rates in the Drosophila genome. [FBrf0151330]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 29. Summary of A-to-I RNA Editing Sites Discovered. [FBrf0213715] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]