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Gene Dmel\CG8051

General Information
Symbol	Dmel\CG8051	Species	D. melanogaster
Name		Annotation symbol	CG8051
Feature type	protein_coding_gene	FlyBase ID	FBgn0031012
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	18C1-18C1	Sequence location	X:19,195,354..19,201,957 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8051 (FBgn0031012). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: secondary active monocarboxylate transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, adult fat body, adult spermathecae. Comments on Affy2 ProbeSet: ProbeSet 1636747_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG8051 expression signal. See the GBrowse view of CG8051 to determine the overlapping gene(s). Gene sequence location is X:19195354..19201957.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA20077
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 18C1-18C1   Limits computationally determined from genome sequence between P{EP}CG8051EP1550&P{EP}EP1300 and P{EP}EP1526&P{EP}PfrxEP1150
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8051 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8051-RA FBtr0074683  NM_133149   2567   616
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8051-PA   FBpp0074452   68.7   616   9.38     NP_573377   AAF48948
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily domain (IPR020846)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48948   AI543681   AQ025371   AQ025493   AW944644   AX699014   AY069861 AAL40006   BG637207   BG640471   BH740781   BH840636   BH840637   BI374027   BI638355   BI640153   CO291142   EC219433
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VWJ0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031012    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031012 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031012 expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr  (137) embryo 14-16hr  (431) embryo 16-18hr  (838) embryo 18-20hr  (1563) embryo 20-22hr  (3514) embryo 22-24hr  (3067) larva L1  (2491) larva L2  (2375) larva L3 12hr old  (1366) larva L3 puffstage 1-2  (1122) larva L3 puffstage 3-6  (800) larva L3 puffstage 7-9  (861) white prepupae new  (580) white prepupae 12hr  (283) white prepupae 24hr  (301) pupae 2d postWPP  (334) pupae 3d postWPP  (388) pupae 4d postWPP  (801) adult male 01day  (1273) adult male 05day  (1286) adult male 30day  (891) adult female 01day  (968) adult female 05day  (458) adult female 30day  (415) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr  (1563) embryo 20-22hr  (3514) embryo 22-24hr  (3067) larva L1  (2491) larva L2  (2375) larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031012 expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr  137 embryo 14-16hr  (431) embryo 16-18hr  (838) embryo 18-20hr  (1563) embryo 20-22hr  (3514) embryo 22-24hr  (3067) larva L1  (2491) larva L2  (2375) larva L3 12hr old  (1366) larva L3 puffstage 1-2  (1122) larva L3 puffstage 3-6  (800) larva L3 puffstage 7-9  (861) white prepupae new  (580) white prepupae 12hr  (283) white prepupae 24hr  (301) pupae 2d postWPP  (334) pupae 3d postWPP  (388) pupae 4d postWPP  (801) adult male 01day  (1273) adult male 05day  (1286) adult male 30day  (891) adult female 01day  (968) adult female 05day  (458) adult female 30day  (415) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr  1563 embryo 20-22hr  (3514) embryo 22-24hr  (3067) larva L1  (2491) larva L2  2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    7 embryo 04-06hr    14 embryo 06-08hr    27 embryo 08-10hr    45 embryo 10-12hr    90 embryo 12-14hr    137 embryo 14-16hr    431 embryo 16-18hr    838 embryo 18-20hr    1563 embryo 20-22hr    3514 embryo 22-24hr    3067 larva L1    2491 larva L2    2375 larva L3 12hr old    1366 larva L3 puffstage 1-2    1122 larva L3 puffstage 3-6    800 larva L3 puffstage 7-9    861 white prepupae new    580 white prepupae 12hr    283 white prepupae 24hr    301 pupae 2d postWPP    334 pupae 3d postWPP    388 pupae 4d postWPP    801 adult male 01day    1273 adult male 05day    1286 adult male 30day    891 adult female 01day    968 adult female 05day    458 adult female 30day    415 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031012    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031012 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, adult fat body, adult spermathecae. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031012 expression level Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland  (545.7) Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031012 expression level Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland  545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.375 Larval Midgut    228.1 Larval Hindgut    161 Larval Malpighian Tubules no informative data Larval Fat Body    59.4 Larval Salivary Gland    54.8 Larval Trachea no informative data Larval Carcass    56.1 Adult Head    46.2 Adult Eye    20.15 Adult Brain    16.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    27.2 Adult Midgut    377.5 Adult Hindgut    311.2 Adult Malpighian Tubules no informative data Adult Fat Body    122.3 Adult Salivary Gland    545.7 Adult Heart    88.675 Adult VirginFemale Spermatheca    201.2 Adult InseminatedFemale Spermatheca    119.5 Adult Ovary    3.8 Adult Testis    46.5 Adult Male Accessory Gland    2.7 Adult Carcass    89.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules no informative data Larval Fat Body     Larval Salivary Gland     Larval Trachea no informative data Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion no informative data Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    46.2   NA  Eye    20.15   NA  Brain    16.9   8.375  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    27.2   228.1  Midgut    377.5   161  Hindgut    311.2   no informative data  Malpighian Tubules    no informative data   59.4  Fat Body    122.3   54.8  Salivary Gland    545.7   NA  Heart    88.675   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    201.2   NA  InseminatedFemale Spermatheca    119.5   NA  Ovary    3.8   NA  Testis    46.5   NA  Male Accessory Gland    2.7   56.1  Carcass    89.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_20
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031012 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8051-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8051GD3447 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG8051 Class Mutagen Stocks Known lesion CG8051EP991 P-element activity 1 -- CG8051KG02574 P-element activity 1 -- CG8051KG05983 P-element activity 1 -- CG8051EP1550 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8051 Class Mutagen Stocks Known lesion CG8051GD3447 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel7468 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3447} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG8051EP991 NA P{EP}CG8051EP1550 NA miscellaneous insertions P{SUPor-P}CG8051KG02574 NA P{SUPor-P}CG8051KG05983 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
secondary active monocarboxylate transmembrane transporter activity inferred from sequence or structural similarity with EMBL:AF059258 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8051 allele Gene References CG8051EP1550 pnr (Pena-Rangel et al., 2002)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59230 DroID - A comprehensive database of gene and protein interactions. • FBgn0031012 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32925
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15995 Dere\GG18061 Dgri\GH12571 Dmoj\GI11135 Dper\GL13009 Dpse\GA25837 Dsec\GM22747 Dsim\GD15585 Dvir\GJ18692 Dwil\GK19797 Dyak\GE17395
Curated drosophilid orthologs
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234863 FBgn0221795 FBgn0205845 FBgn0187250 FBgn0177617 FBgn0247214 FBgn0150615 FBgn0133896 FBgn0120050 FBgn0110278 FBgn0093018
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	10145 w1118 P{EP}CG8051EP991 13485 y1 P{SUPor-P}CG8051KG02574 14136 y1 P{SUPor-P}CG8051KG05983
VDRC	v45189 w1118; P{GD3447}v45189/TM3
Genomic Clones ( 2 )
	BACR02B03 BACR48C12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 8 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD10554
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE61533 SD11493 SD15088 SD20624 SD22954
Other clones	CK01.98C.G10 EK076244
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031012 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32925
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG8051 anon-WO03002137.1 (FlyBase, 1996-)
Additional comments	Source for merge of CG8051 anon-WO03002137.1 was sequence comparison (date:031211). (FlyBase, 1996-)
Other Comments
	snmRNA:763 is derived from the ORF of CG8051. (Yuan et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_133149 RefSeq (Proteins) • NP_573377 DDBJ / EMBL / GenBank • AAF48948 AAL40006 AI543681 AQ025371 AQ025493 AW944644 AX699014 AY069861 BH740781 BH840636 BH840637 Entrez Gene - A searchable database of RefSeq genes. • 32925 UniProtKB/TrEMBL • Q9VWJ0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily domain (IPR020846)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59230 DroID - A comprehensive database of gene and protein interactions. • FBgn0031012 DRSC - Results from RNAi screens. • FBgn0031012 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031012 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8051-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031012 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32925 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32925 modMine - Data generated by the modENCODE project. • FBgn0031012 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234863 FBgn0221795 FBgn0205845 FBgn0187250 FBgn0177617 FBgn0247214 FBgn0150615 FBgn0133896 FBgn0120050 FBgn0110278 FBgn0093018
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	anon-WO03002137.1   CG8051   EP(X)1550 (Pena-Rangel et al., 2002)
Name Synonym
Secondary FlyBase IDs
	FBgn0065991
References ( 14 )
Research paper	Yuan et al., 2003, Nucleic Acids Res. 31(10): 2495--2507 RNomics in Drosophila melanogaster: identification of 66 candidates for novel non-messenger RNAs. [FBrf0159270] Pena-Rangel et al., 2002, Genetics 160(3): 1035--1050 A misexpression study examining dorsal thorax formation in Drosophila melanogaster. [FBrf0147055]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Patent	Eulenberg et al., 2003, World Patent 03002137: Trp1, mct, or ftz-f1 homologous proteins involved in the regulation of energy homeostasis. [FBrf0198951]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]