FB2021_06, released December 14, 2021

Gene: Dmel\CG14207

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General Information
Symbol
Dmel\CG14207
Species
D. melanogaster
Name
Annotation Symbol
CG14207
Feature Type
protein_coding_gene
FlyBase ID
FBgn0031037
Gene Model Status
Current
Stock Availability
13 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

HspB8

Key Links
Genomic Location
Cytogenetic map
18D3-18D3
Sequence location
Recombination map
1-63
RefSeq locus
NC_004354 REGION:19605199..19611413
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (6 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables unfolded protein binding
inferred from sequence model
(Li et al., 2009)
Biological Process (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in protein refolding
inferred from direct assay
(Vos et al., 2016)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in chaperone-mediated protein folding
inferred from sequence model
(Li et al., 2009)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
located_in cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
located_in nucleoplasm
inferred from high throughput direct assay
(Lye et al., 2014)
colocalizes_with Z disc
inferred from direct assay
(Carra et al., 2010)
located_in Z disc
inferred from direct assay
(Lowe et al., 2014, Arndt et al., 2010)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
SMALL HEAT SHOCK PROTEINS -
The small Heat Shock Protein (sHSP) family is characterized by the presence of an α-crystallin domain. sHSPs play a crucial role in protein folding. Most sHSPs have the ability to prevent protein aggregation and to maintain substrate proteins in a refoldable state. (Adapted from FBrf0228040 and FBrf0231212).
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\CG14207 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.49

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
CG14207-RA
FBtr0074733
NM_134482
1240
183
CG14207-RB
FBtr0074734
NM_167669
1267
192
CG14207-RC
FBtr0307161
NM_001258831
753
154
CG14207-RD
FBtr0345918
NM_001298517
1380
183
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
CG14207-PA
FBpp0074502
20.8
183
5.74
NP_608326
AAF48980
CG14207-PB
FBpp0074503
21.8
192
6.54
NP_728275
AAN09508
CG14207-PC
FBpp0297990
17.1
154
9.42
NP_001245760
AFH07472
CG14207-PD
FBpp0311833
20.8
183
5.74
NP_001285446
AHN59916
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

183 aa isoforms: CG14207-PA, CG14207-PD
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG14207 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
located_in nucleoplasm
inferred from high throughput direct assay
(Lye et al., 2014)
colocalizes_with Z disc
inferred from direct assay
(Carra et al., 2010)
located_in Z disc
inferred from direct assay
(Lowe et al., 2014, Arndt et al., 2010)
Expression Deduced from Reporters
Reporter: PBac{810.P.FSVS-2}CG14207CPTI004445
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
pedunculus of adult mushroom body
(Knowles-Barley, 2011.8.24)
calyx of adult mushroom body
(Knowles-Barley, 2011.8.24)
adult antennal lobe glomerulus | subset

Comment: patterned expression in adult antennal lobe, higher in some adult antennal lobe glomeruli

(Knowles-Barley, 2011.8.24)
adult brain cell body rind
(Knowles-Barley, 2011.8.24)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\CG14207 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 16 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of CG14207
Transgenic constructs containing regulatory region of CG14207
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 0 )
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (11)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\CRYAA
5 of 15
Yes
No
Hsap\HSPB1
5 of 15
Yes
Yes
2  
Hsap\CRYAB
4 of 15
No
No
6  
Hsap\CRYAA2
3 of 15
No
No
Hsap\HSPB2
3 of 15
No
No
Hsap\HSPB3
3 of 15
No
Yes
Hsap\HSPB8
3 of 15
No
Yes
4  
Hsap\HSPB6
2 of 15
No
No
Hsap\HSPB7
2 of 15
No
Yes
1  
Hsap\HSPB9
2 of 15
No
Yes
Hsap\HSPB2-C11orf52
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Cryaa
5 of 15
Yes
No
Mmus\Cryab
5 of 15
Yes
No
Mmus\Hspb1
4 of 15
No
Yes
Mmus\Hspb2
3 of 15
No
No
Mmus\Hspb3
3 of 15
No
Yes
Mmus\Hspb6
3 of 15
No
No
Mmus\Hspb7
2 of 15
No
Yes
Mmus\Hspb8
2 of 15
No
No
Mmus\Hspb9
2 of 15
No
No
Rattus norvegicus (Norway rat) (9)
Rnor\Cryaa
4 of 13
Yes
No
Rnor\Cryab
4 of 13
Yes
No
Rnor\Hspb1
4 of 13
Yes
Yes
Rnor\Hspb2
3 of 13
No
No
Rnor\Hspb3
3 of 13
No
Yes
Rnor\Hspb6
3 of 13
No
No
Rnor\Hspb8
3 of 13
No
Yes
Rnor\Hspb7
2 of 13
No
Yes
Rnor\Hspb9
2 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (13)
Xtro\cryaa
4 of 12
Yes
No
Xtro\cryab
4 of 12
Yes
No
Xtro\hspb1
4 of 12
Yes
No
Xtro\hsp30d
3 of 12
No
No
Xtro\hspb2
3 of 12
No
No
Xtro\hspb3
3 of 12
No
Yes
Xtro\hspb6
3 of 12
No
No
Xtro\hspb8
3 of 12
No
Yes
Xtro\hsp30e
2 of 12
No
No
Xtro\uqcrh
2 of 12
No
No
Xtro\LOC100489058
1 of 12
No
No
Xtro\LOC100489207
1 of 12
No
No
Xtro\LOC100491399
1 of 12
No
No
Danio rerio (Zebrafish) (13)
Drer\cryaa
5 of 15
Yes
No
Drer\hspb1
5 of 15
Yes
No
Drer\cryaba
4 of 15
No
No
Drer\cryabb
4 of 15
No
No
Drer\hspb11
4 of 15
No
No
Drer\hspb15
4 of 15
No
Yes
Drer\si:dkey-1k23.3
4 of 15
No
Yes
Drer\hspb2
3 of 15
No
No
Drer\hspb3
3 of 15
No
Yes
Drer\hspb6
3 of 15
No
No
Drer\hspb8
3 of 15
No
Yes
Drer\hspb9
3 of 15
No
No
Drer\hspb7
2 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (19)
Cele\hsp-25
14 of 15
Yes
Yes
Cele\hsp-12.2
3 of 15
No
No
Cele\hsp-12.6
3 of 15
No
No
Cele\hsp-16.2
3 of 15
No
No
Cele\hsp-17
3 of 15
No
No
Cele\F08H9.3
2 of 15
No
No
Cele\F08H9.4
2 of 15
No
No
Cele\hsp-12.1
2 of 15
No
No
Cele\hsp-12.3
2 of 15
No
No
Cele\hsp-16.11
2 of 15
No
No
Cele\hsp-16.41
2 of 15
No
No
Cele\hsp-16.49
2 of 15
No
No
Cele\hsp-43
2 of 15
No
No
Cele\sip-1
2 of 15
No
No
Cele\Y55F3BR.6
2 of 15
No
No
Cele\ZK1128.7
2 of 15
No
No
Cele\F58H7.1
1 of 15
No
Yes
Cele\hsp-16.1
1 of 15
No
No
Cele\hsp-16.48
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (17)
Atha\AT1G52560
2 of 9
Yes
Yes
Atha\HSP21
2 of 9
Yes
Yes
Atha\AT1G07400
1 of 9
No
No
Atha\AT1G53540
1 of 9
No
No
Atha\AT1G54050
1 of 9
No
No
Atha\AT1G59860
1 of 9
No
No
Atha\AT2G19310
1 of 9
No
Yes
Atha\AT2G29500
1 of 9
No
No
Atha\AT4G21870
1 of 9
No
No
Atha\AT5G37670
1 of 9
No
No
Atha\AT5G51440
1 of 9
No
Yes
Atha\ATHSP22.0
1 of 9
No
No
Atha\HSP17.4
1 of 9
No
No
Atha\HSP17.6A
1 of 9
No
No
Atha\HSP17.6II
1 of 9
No
No
Atha\HSP18.2
1 of 9
No
No
Atha\HSP23.6-MITO
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\hsp16
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190GTG )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Dsim\GD24875
Drosophila sechellia
Dsec\GM22970
Drosophila erecta
Dere\GG19234
Drosophila yakuba
Dyak\GE15853
Drosophila ananassae
Dana\GF20408
Drosophila pseudoobscura pseudoobscura
Dpse\GA12823
Drosophila persimilis
Dper\GL27055
Drosophila willistoni
Dwil\GK25198
Drosophila virilis
Dvir\GJ15970
Drosophila mojavensis
Dmoj\GI11114
Drosophila grimshawi
Dgri\GH24938
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150D6H )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17023722
Glossina morsitans
Tsetse fly
Gmor\GMOY000497
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_05314
Mayetiola destructor
Hessian fly
Mdes\Mdes016654
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL001094
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015090
Anopheles darlingi
American malaria mosquito
Adar\ADAC003522
Anopheles gambiae
Malaria mosquito
Agam\AGAP000941
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ009818
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0PT6 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\Hsp21.4
Danaus plexippus
Monarch butterfly
Dple\DPOGS207471-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL004675
Apis florea
Little honeybee
Aflo\2189778276
Apis florea
Little honeybee
Aflo\2189778340
Apis florea
Little honeybee
Aflo\2163524994
Apis mellifera
Western honey bee
Amel\GB53550
Apis mellifera
Western honey bee
Amel\GB53549
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19987
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19986
Bombus terrestris
Buff-tailed bumblebee
Bter\15211846
Linepithema humile
Argentine ant
Lhum\LH19962
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00132f
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005422
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11016
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11015
Tribolium castaneum
Red flour beetle
Tcas\TC001152
Pediculus humanus
Human body louse
Phum\PHUM217050
Pediculus humanus
Human body louse
Phum\PHUM217060
Pediculus humanus
Human body louse
Phum\PHUM217070
Pediculus humanus
Human body louse
Phum\PHUM621170
Rhodnius prolixus
Kissing bug
Rpro\RPRC008537
Cimex lectularius
Bed bug
Clec\CLEC025338
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003907
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09290
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0Q4E )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR004724
Ixodes scapularis
Black-legged tick
Isca\ISCW017709
Stegodyphus mimosarum
African social velvet spider
Smim\KFM69864.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65662.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g02770
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_208978
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (10)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Hsp26
5 of 10
Hsp67Ba
5 of 10
l(2)efl
5 of 10
Hsp23
4 of 10
Hsp27
4 of 10
Hsp67Bc
4 of 10
CG4461
3 of 10
CG7409
3 of 10
CG13133
3 of 10
Hsp22
3 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 6 )
    Modifiers Based on Experimental Evidence ( 1 )
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CRYAA; crystallin alpha A
    5 of 15
    123580
    HSPB1; heat shock protein family B (small) member 1
    5 of 15
    602195
     
    CRYAB; crystallin alpha B
    4 of 15
    123590
     
    Hsap\CRYAA2
    3 of 15
        HSPB2; heat shock protein family B (small) member 2
        3 of 15
        602179
            HSPB3; heat shock protein family B (small) member 3
            3 of 15
            604624
            HSPB8; heat shock protein family B (small) member 8
            3 of 15
            608014
             
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            esyN Network Diagram
            Show neighbor-neighbor interactions:
            Select Layout:
            Legend:
            Protein
            RNA
            Selected Interactor(s)
            Interactions Browser
            View in Interactions Browser
            Please see the Physical Interaction reports below for full details
            protein-protein
            Physical Interaction
            Assay
            References
            CG14207 - Act79B
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Actn
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Adh
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Ald1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Argk1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - CG10581
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - CG5177
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - E(spl)m3-HLH
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Fer2LCH
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Gpdh1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Mf
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Mhc
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Mlc1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Mlc2
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Obp56d
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Prm
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Scp1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Snr1
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Spc25
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - Tm2
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - TpnC41C
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - kdn
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - lolal
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - p38b
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - spag
            anti tag coimmunoprecipitation, peptide massfingerprinting
            (Benbahouche et al., 2014)
            CG14207 - up
            experimental knowledge based
            (Guruharsha et al., 2011)
            CG14207 - wupA
            experimental knowledge based
            (Guruharsha et al., 2011)
            Summary of Genetic Interactions
            esyN Network Diagram
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            External Data
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
            External Data
            Linkouts
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            X
            Recombination map
            1-63
            Cytogenetic map
            18D3-18D3
            Sequence location
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            18D3-18D3
            Limits computationally determined from genome sequence between P{EP}EP1348&P{EP}e(y)3EP1036 and P{EP}Sec61γEP1511
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            Experimentally Determined Recombination Data
            Location

            1-63

            (FlyBase, 2016)

            1-62.2

            (Comeron et al., 2012)
            Left of (cM)
            Right of (cM)
            Notes
            Stocks and Reagents
            Stocks (13)
            Genomic Clones (9)
             

            Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

            cDNA Clones (126)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
            Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
            RNAi and Array Information
            Linkouts
            DRSC - Results frm RNAi screens
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            Antibody Information
            Laboratory Generated Antibodies
             
            Commercially Available Antibodies
             
            Other Information
            Relationship to Other Genes
            Source for database identify of
            Source for database merge of
            Additional comments

            FlyBase Curator comment: Authors of FBrf0209888 say that 'CG14207' is "an uncharacterized fly homolog of [mammalian] HspB8", whereas FBrf0212431 shows there are several candidate genes for being this ortholog and actually conclude that 'Hsp67Bc' ('CG4190') is "the closest functional ortholog of human HSPB8". 'CG14207' has not been given the symbol 'HspB8' for this reason.

            (Arndt et al., 2010)
            Other Comments
            Origin and Etymology
            Discoverer
            Etymology
            Identification
            External Crossreferences and Linkouts ( 55 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            MARRVEL_MODEL - MARRVEL (model organism gene)
            modMine - A data warehouse for the modENCODE project
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyMine - An integrated database for Drosophila genomics
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Synonyms and Secondary IDs (7)
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (75)