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Gene Dmel\CG14207

General Information
Symbol	Dmel\CG14207	Species	D. melanogaster
Name		Annotation symbol	CG14207
Feature type	protein_coding_gene	FlyBase ID	FBgn0031037
Gene Model Status	Current	Stock availability	9 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	18D3-18D3	Sequence location	X:19,499,232..19,505,306 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG14207 (FBgn0031037). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Alpha crystallin/Heat shock protein; Alpha crystallin/Hsp20 domain; HSP20-like chaperone. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, inseminated spermatheca, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult brain, larval/adult midgut, adult Malpighian tubules, adult fat body, adult salivary gland, adult female reproductive system, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1633483_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG14207. Gene sequence location is X:19499232..19505306.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 18D3-18D3   Limits computationally determined from genome sequence between P{EP}EP1348&P{EP}e(y)3EP1036 and P{EP}Sec61γEP1511
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG14207 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG14207-RA FBtr0074733  NM_134482   1240   183 CG14207-RB FBtr0074734  NM_167669   1267   192 CG14207-RC FBtr0307161  NM_001258831   753   154
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG14207-PA   FBpp0074502   20.8   183   5.74     NP_608326   AAF48980 CG14207-PB   FBpp0074503   21.8   192   6.54     NP_728275   AAN09508 CG14207-PC   FBpp0297990   17.1   154   9.42     NP_001245760   AFH07472
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Alpha crystallin/Heat shock protein (IPR001436) Alpha crystallin/Hsp20 domain (IPR002068) HSP20-like chaperone (IPR008978)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440408   AA540502   AA694831   AA950406   AA950407   AE014298 AAF48980   AE014298 AAN09508   AE014298 AFH07472   AI064522   AI108154   AI293959   AI294422   AI296744   AI297444   AI386530   AI456979   AK281439   AQ025353   AW943370   AY061439 AAL28987   BI163274   BI164785   BI167141   BI167383   BI168640   BI171519   BI212264   BI227710   BI227928   BI232448   BI234378   BI235042   BI235396   BI238399   BI239235   BI242998   BI353259   BI357435   BI361382   BI361735   BI362863   BI363873   BI366699   BI366706   BI367360   BI368046   BI368760   BI373084   BI483758   BI484034   BI486094   BI486597   BI486850   BI486998   BI577709   BI579579   BI580635   BI620646   BP542263   BP542375   BP546256   BP552470   BP552471   BT081373   BT088758   BT088760   BT120097   BZ748899   CK132151   CO182734   CO195192   CO195440   CO262937   CO267028   CO267700   CO276289   CO277865   CO284510   CO287969   CO288782   CO293160   CO294084   CO297196   CO297419   CO300599   CO313590   CO314708   CO316723   CO316812   CZ476401   CZ482117   CZ483708   CZ483709   CZ486230   CZ486231   CZ486232   CZ486233   EC061035   EC061455   EC073189   EC080020   EC085648   EC087313   EC087398   EC196757   EC201772   EC201888   EC201986   EC208933   EC212893   EC215402   EC217357   EC224214   EC237237   EC238542   EC241996   EC242077   EC247310   EC248757   EC248865   EV597077   GH941976   GH943765   GH944082   GH944269   GH946806   GH947461   GH947802   GH948560   GH955562   GH955981   GH958759   GH961880   GH963738   GH963964   GH965647   GH966392   GH966648   GH970848   GH972189   GH972619   GH973813   GH974065   GH974832   GH975249   GH976303   GH984780
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IQW5 Q9VWG1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 9 -- 10   trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   dorsal pharyngeal muscle primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic/larval dorsal vessel   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Z disc inferred from direct assay (Arndt et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, inseminated spermatheca, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult brain, larval/adult midgut, adult Malpighian tubules, adult fat body, adult salivary gland, adult female reproductive system, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut    2076.2 Larval Malpighian Tubules    874.3 Larval Fat Body    2108.6 Larval Salivary Gland    1381.6 Larval Trachea    891.1 Larval Carcass    3888.675 Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop    3418.4 Adult Midgut    331.7 Adult Hindgut    2342.3 Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass    1223.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (573.525) Larval Midgut    416.3 Larval Hindgut  (2076.2) Larval Malpighian Tubules  (874.3) Larval Fat Body  (2108.6) Larval Salivary Gland  (1381.6) Larval Trachea  (891.1) Larval Carcass  (3888.675) Adult Head  (712.2) Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion  (614) Adult Crop  (3418.4) Adult Midgut    331.7 Adult Hindgut  (2342.3) Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart  (994.9) Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca  (649.8) Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass  (1223.2) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut  (2076.2) Larval Malpighian Tubules    874.3 Larval Fat Body  (2108.6) Larval Salivary Gland  (1381.6) Larval Trachea    891.1 Larval Carcass  (3888.675) Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop  (3418.4) Adult Midgut    331.7 Adult Hindgut  (2342.3) Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass  (1223.2) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut    2076.2 Larval Malpighian Tubules    874.3 Larval Fat Body    2108.6 Larval Salivary Gland    1381.6 Larval Trachea    891.1 Larval Carcass    3888.675 Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop    3418.4 Adult Midgut    331.7 Adult Hindgut    2342.3 Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass    1223.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut    2076.2 Larval Malpighian Tubules    874.3 Larval Fat Body    2108.6 Larval Salivary Gland    1381.6 Larval Trachea    891.1 Larval Carcass    3888.675 Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop    3418.4 Adult Midgut    331.7 Adult Hindgut    2342.3 Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass    1223.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  573.525 Larval Midgut    416.3 Larval Hindgut  (2076.2) Larval Malpighian Tubules  (874.3) Larval Fat Body  (2108.6) Larval Salivary Gland  (1381.6) Larval Trachea  (891.1) Larval Carcass  (3888.675) Adult Head  712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion  614 Adult Crop  (3418.4) Adult Midgut    331.7 Adult Hindgut  (2342.3) Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart  (994.9) Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca  649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass  (1223.2) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut  (2076.2) Larval Malpighian Tubules    874.3 Larval Fat Body  (2108.6) Larval Salivary Gland  1381.6 Larval Trachea    891.1 Larval Carcass  (3888.675) Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop  (3418.4) Adult Midgut    331.7 Adult Hindgut  (2342.3) Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass  1223.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    573.525 Larval Midgut    416.3 Larval Hindgut    2076.2 Larval Malpighian Tubules    874.3 Larval Fat Body    2108.6 Larval Salivary Gland    1381.6 Larval Trachea    891.1 Larval Carcass    3888.675 Adult Head    712.2 Adult Eye    300.75 Adult Brain    395.8 Adult Thoracic-Abdominal Ganglion    614 Adult Crop    3418.4 Adult Midgut    331.7 Adult Hindgut    2342.3 Adult Malpighian Tubules    419.5 Adult Fat Body    400.1 Adult Salivary Gland    289.7 Adult Heart    994.9 Adult VirginFemale Spermatheca    479.3 Adult InseminatedFemale Spermatheca    649.8 Adult Ovary    329.4 Adult Testis    116.8 Adult Male Accessory Gland    232.1 Adult Carcass    1223.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    712.2   NA  Eye    300.75   NA  Brain    395.8   573.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    614   NA  Crop    3418.4   416.3  Midgut    331.7   2076.2  Hindgut    2342.3   874.3  Malpighian Tubules    419.5   2108.6  Fat Body    400.1   1381.6  Salivary Gland    289.7   NA  Heart    994.9   891.1  Trachea    NA   NA  VirginFemale Spermatheca    479.3   NA  InseminatedFemale Spermatheca    649.8   NA  Ovary    329.4   NA  Testis    116.8   NA  Male Accessory Gland    232.1   3888.675  Carcass    1223.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3    195 central nervous system, pupae P8    114 head, virgin 1-day female    278 head, virgin 4-day female    176 head, virgin 20-day female    110 head, mated 1-day female    240 head, mated 4-day female    182 head, mated 20-day female    107 head, mated 1-day male    277 head, mated 4-day male    177 head, mated 20-day male    193 salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering    139 digestive system, 1-day adult    144 digestive system, 4-day adult    113 digestive system, 20-day adult    75 fat body, larvae L3 wandering    314 fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering    1549 carcass, 1-day adult    558 carcass, 4-day adult    315 carcass, 20-day adult    285 ovary, virgin 4-day female    110 ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (85) central nervous system, larvae L3  (195) central nervous system, pupae P8  (114) head, virgin 1-day female  (278) head, virgin 4-day female  (176) head, virgin 20-day female  (110) head, mated 1-day female  (240) head, mated 4-day female  (182) head, mated 20-day female  (107) head, mated 1-day male  (277) head, mated 4-day male  (177) head, mated 20-day male  (193) salivary gland, larvae L3 wandering  (83) salivary gland, white prepupae  (58) digestive system, larvae L3 wandering  (139) digestive system, 1-day adult  (144) digestive system, 4-day adult  (113) digestive system, 20-day adult  (75) fat body, larvae L3 wandering  (314) fat body, white prepupae  (89) fat body, pupae P8  (69) carcass, larvae L3 wandering  (1549) carcass, 1-day adult  (558) carcass, 4-day adult  (315) carcass, 20-day adult  (285) ovary, virgin 4-day female  (110) ovary, mated 4-day female  (75) testis, mated 4-day male  (57) accessory gland, mated 4-day male  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3  (195) central nervous system, pupae P8  (114) head, virgin 1-day female  (278) head, virgin 4-day female  (176) head, virgin 20-day female  (110) head, mated 1-day female  (240) head, mated 4-day female  (182) head, mated 20-day female  107 head, mated 1-day male  (277) head, mated 4-day male  (177) head, mated 20-day male  (193) salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering  (139) digestive system, 1-day adult  (144) digestive system, 4-day adult  (113) digestive system, 20-day adult    75 fat body, larvae L3 wandering  (314) fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering  (1549) carcass, 1-day adult  (558) carcass, 4-day adult  (315) carcass, 20-day adult  (285) ovary, virgin 4-day female  (110) ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3    195 central nervous system, pupae P8    114 head, virgin 1-day female    278 head, virgin 4-day female    176 head, virgin 20-day female    110 head, mated 1-day female    240 head, mated 4-day female    182 head, mated 20-day female    107 head, mated 1-day male    277 head, mated 4-day male    177 head, mated 20-day male    193 salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering    139 digestive system, 1-day adult    144 digestive system, 4-day adult    113 digestive system, 20-day adult    75 fat body, larvae L3 wandering    314 fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering    1549 carcass, 1-day adult    558 carcass, 4-day adult    315 carcass, 20-day adult    285 ovary, virgin 4-day female    110 ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3    195 central nervous system, pupae P8    114 head, virgin 1-day female    278 head, virgin 4-day female    176 head, virgin 20-day female    110 head, mated 1-day female    240 head, mated 4-day female    182 head, mated 20-day female    107 head, mated 1-day male    277 head, mated 4-day male    177 head, mated 20-day male    193 salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering    139 digestive system, 1-day adult    144 digestive system, 4-day adult    113 digestive system, 20-day adult    75 fat body, larvae L3 wandering    314 fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering    1549 carcass, 1-day adult    558 carcass, 4-day adult    315 carcass, 20-day adult    285 ovary, virgin 4-day female    110 ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (85) central nervous system, larvae L3  (195) central nervous system, pupae P8  (114) head, virgin 1-day female  (278) head, virgin 4-day female  (176) head, virgin 20-day female  (110) head, mated 1-day female  (240) head, mated 4-day female  (182) head, mated 20-day female  (107) head, mated 1-day male  (277) head, mated 4-day male  (177) head, mated 20-day male  (193) salivary gland, larvae L3 wandering  (83) salivary gland, white prepupae  (58) digestive system, larvae L3 wandering  (139) digestive system, 1-day adult  (144) digestive system, 4-day adult  (113) digestive system, 20-day adult  (75) fat body, larvae L3 wandering  (314) fat body, white prepupae  (89) fat body, pupae P8  (69) carcass, larvae L3 wandering  (1549) carcass, 1-day adult  (558) carcass, 4-day adult  (315) carcass, 20-day adult  (285) ovary, virgin 4-day female  (110) ovary, mated 4-day female  (75) testis, mated 4-day male  (57) accessory gland, mated 4-day male  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3  (195) central nervous system, pupae P8  114 head, virgin 1-day female  (278) head, virgin 4-day female  (176) head, virgin 20-day female  110 head, mated 1-day female  (240) head, mated 4-day female  (182) head, mated 20-day female  107 head, mated 1-day male  (277) head, mated 4-day male  (177) head, mated 20-day male  (193) salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering  139 digestive system, 1-day adult  (144) digestive system, 4-day adult  113 digestive system, 20-day adult    75 fat body, larvae L3 wandering  (314) fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering  (1549) carcass, 1-day adult  (558) carcass, 4-day adult  (315) carcass, 20-day adult  (285) ovary, virgin 4-day female  110 ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    85 central nervous system, larvae L3    195 central nervous system, pupae P8    114 head, virgin 1-day female    278 head, virgin 4-day female    176 head, virgin 20-day female    110 head, mated 1-day female    240 head, mated 4-day female    182 head, mated 20-day female    107 head, mated 1-day male    277 head, mated 4-day male    177 head, mated 20-day male    193 salivary gland, larvae L3 wandering    83 salivary gland, white prepupae    58 digestive system, larvae L3 wandering    139 digestive system, 1-day adult    144 digestive system, 4-day adult    113 digestive system, 20-day adult    75 fat body, larvae L3 wandering    314 fat body, white prepupae    89 fat body, pupae P8    69 carcass, larvae L3 wandering    1549 carcass, 1-day adult    558 carcass, 4-day adult    315 carcass, 20-day adult    285 ovary, virgin 4-day female    110 ovary, mated 4-day female    75 testis, mated 4-day male    57 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr    103 embryo 10-12hr    143 embryo 12-14hr    148 embryo 14-16hr    202 embryo 16-18hr    304 embryo 18-20hr    459 embryo 20-22hr    375 embryo 22-24hr    394 larva L1    203 larva L2    176 larva L3 12hr old    191 larva L3 puffstage 1-2    268 larva L3 puffstage 3-6    499 larva L3 puffstage 7-9    842 white prepupae new    575 white prepupae 12hr    158 white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP    342 pupae 4d postWPP    274 adult male 01day    162 adult male 05day    126 adult male 30day    128 adult female 01day    125 adult female 05day    62 adult female 30day    64 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (65) embryo 04-06hr  (38) embryo 06-08hr  (71) embryo 08-10hr  (103) embryo 10-12hr  (143) embryo 12-14hr  (148) embryo 14-16hr  (202) embryo 16-18hr  (304) embryo 18-20hr  (459) embryo 20-22hr  (375) embryo 22-24hr  (394) larva L1  (203) larva L2  (176) larva L3 12hr old  (191) larva L3 puffstage 1-2  (268) larva L3 puffstage 3-6  (499) larva L3 puffstage 7-9  (842) white prepupae new  (575) white prepupae 12hr  (158) white prepupae 24hr  (87) pupae 2d postWPP  (93) pupae 3d postWPP  (342) pupae 4d postWPP  (274) adult male 01day  (162) adult male 05day  (126) adult male 30day  (128) adult female 01day  (125) adult female 05day  (62) adult female 30day  (64) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr  103 embryo 10-12hr  (143) embryo 12-14hr  (148) embryo 14-16hr  (202) embryo 16-18hr  (304) embryo 18-20hr  (459) embryo 20-22hr  (375) embryo 22-24hr  (394) larva L1  (203) larva L2  (176) larva L3 12hr old  (191) larva L3 puffstage 1-2  (268) larva L3 puffstage 3-6  (499) larva L3 puffstage 7-9  (842) white prepupae new  (575) white prepupae 12hr  (158) white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP  (342) pupae 4d postWPP  (274) adult male 01day  (162) adult male 05day  (126) adult male 30day  (128) adult female 01day  (125) adult female 05day    62 adult female 30day    64 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr    103 embryo 10-12hr    143 embryo 12-14hr    148 embryo 14-16hr    202 embryo 16-18hr    304 embryo 18-20hr    459 embryo 20-22hr    375 embryo 22-24hr    394 larva L1    203 larva L2    176 larva L3 12hr old    191 larva L3 puffstage 1-2    268 larva L3 puffstage 3-6    499 larva L3 puffstage 7-9    842 white prepupae new    575 white prepupae 12hr    158 white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP    342 pupae 4d postWPP    274 adult male 01day    162 adult male 05day    126 adult male 30day    128 adult female 01day    125 adult female 05day    62 adult female 30day    64 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr    103 embryo 10-12hr    143 embryo 12-14hr    148 embryo 14-16hr    202 embryo 16-18hr    304 embryo 18-20hr    459 embryo 20-22hr    375 embryo 22-24hr    394 larva L1    203 larva L2    176 larva L3 12hr old    191 larva L3 puffstage 1-2    268 larva L3 puffstage 3-6    499 larva L3 puffstage 7-9    842 white prepupae new    575 white prepupae 12hr    158 white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP    342 pupae 4d postWPP    274 adult male 01day    162 adult male 05day    126 adult male 30day    128 adult female 01day    125 adult female 05day    62 adult female 30day    64 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (65) embryo 04-06hr  (38) embryo 06-08hr  (71) embryo 08-10hr  (103) embryo 10-12hr  (143) embryo 12-14hr  (148) embryo 14-16hr  (202) embryo 16-18hr  (304) embryo 18-20hr  (459) embryo 20-22hr  (375) embryo 22-24hr  (394) larva L1  (203) larva L2  (176) larva L3 12hr old  (191) larva L3 puffstage 1-2  (268) larva L3 puffstage 3-6  (499) larva L3 puffstage 7-9  (842) white prepupae new  (575) white prepupae 12hr  (158) white prepupae 24hr  (87) pupae 2d postWPP  (93) pupae 3d postWPP  (342) pupae 4d postWPP  (274) adult male 01day  (162) adult male 05day  (126) adult male 30day  (128) adult female 01day  (125) adult female 05day  (62) adult female 30day  (64) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr  103 embryo 10-12hr  143 embryo 12-14hr  (148) embryo 14-16hr  (202) embryo 16-18hr  (304) embryo 18-20hr  (459) embryo 20-22hr  (375) embryo 22-24hr  (394) larva L1  (203) larva L2  (176) larva L3 12hr old  (191) larva L3 puffstage 1-2  (268) larva L3 puffstage 3-6  (499) larva L3 puffstage 7-9  (842) white prepupae new  (575) white prepupae 12hr  (158) white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP  (342) pupae 4d postWPP  (274) adult male 01day  (162) adult male 05day  126 adult male 30day  128 adult female 01day  125 adult female 05day    62 adult female 30day    64 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    65 embryo 04-06hr    38 embryo 06-08hr    71 embryo 08-10hr    103 embryo 10-12hr    143 embryo 12-14hr    148 embryo 14-16hr    202 embryo 16-18hr    304 embryo 18-20hr    459 embryo 20-22hr    375 embryo 22-24hr    394 larva L1    203 larva L2    176 larva L3 12hr old    191 larva L3 puffstage 1-2    268 larva L3 puffstage 3-6    499 larva L3 puffstage 7-9    842 white prepupae new    575 white prepupae 12hr    158 white prepupae 24hr    87 pupae 2d postWPP    93 pupae 3d postWPP    342 pupae 4d postWPP    274 adult male 01day    162 adult male 05day    126 adult male 30day    128 adult female 01day    125 adult female 05day    62 adult female 30day    64 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    246 embryonic 1182-4H    116 embryonic GM2    106 embryonic Kc167    75 embryonic S1    67 embryonic S3    137 leg disc CME L1    432 wing disc CME-W2    129 wing disc ML-DmD8    78 wing disc ML-DmD9    178 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    101 wing disc ML-DmD32    124 haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11    145 antennal disc ML-DmD20-c5    169 mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    152 ovary fGS/OSS    255 ovary OSC    127 ovary OSS    116 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4  (246) embryonic 1182-4H  (116) embryonic GM2  (106) embryonic Kc167  (75) embryonic S1  (67) embryonic S3  (137) leg disc CME L1  (432) wing disc CME-W2  (129) wing disc ML-DmD8  (78) wing disc ML-DmD9  (178) wing disc ML-DmD16-c3  (80) wing disc ML-DmD21  (101) wing disc ML-DmD32  (124) haltere disc ML-DmD17-c3  (91) eye-antennal disc ML-DmD11  (145) antennal disc ML-DmD20-c5  (169) mixed discs ML-DmD4-c1  (88) CNS ML-DmBG1-c1  (88) CNS ML-DmBG2-c2  (38) tumorous blood cells mbn2  (152) ovary fGS/OSS  (255) ovary OSC  (127) ovary OSS  (116) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4  (246) embryonic 1182-4H  (116) embryonic GM2  106 embryonic Kc167    75 embryonic S1    67 embryonic S3  (137) leg disc CME L1  (432) wing disc CME-W2  (129) wing disc ML-DmD8    78 wing disc ML-DmD9  (178) wing disc ML-DmD16-c3    80 wing disc ML-DmD21  101 wing disc ML-DmD32  (124) haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11  (145) antennal disc ML-DmD20-c5  (169) mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2  (152) ovary fGS/OSS  (255) ovary OSC  (127) ovary OSS  (116) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    246 embryonic 1182-4H    116 embryonic GM2    106 embryonic Kc167    75 embryonic S1    67 embryonic S3    137 leg disc CME L1    432 wing disc CME-W2    129 wing disc ML-DmD8    78 wing disc ML-DmD9    178 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    101 wing disc ML-DmD32    124 haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11    145 antennal disc ML-DmD20-c5    169 mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    152 ovary fGS/OSS    255 ovary OSC    127 ovary OSS    116 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    246 embryonic 1182-4H    116 embryonic GM2    106 embryonic Kc167    75 embryonic S1    67 embryonic S3    137 leg disc CME L1    432 wing disc CME-W2    129 wing disc ML-DmD8    78 wing disc ML-DmD9    178 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    101 wing disc ML-DmD32    124 haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11    145 antennal disc ML-DmD20-c5    169 mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    152 ovary fGS/OSS    255 ovary OSC    127 ovary OSS    116 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4  (246) embryonic 1182-4H  (116) embryonic GM2  (106) embryonic Kc167  (75) embryonic S1  (67) embryonic S3  (137) leg disc CME L1  (432) wing disc CME-W2  (129) wing disc ML-DmD8  (78) wing disc ML-DmD9  (178) wing disc ML-DmD16-c3  (80) wing disc ML-DmD21  (101) wing disc ML-DmD32  (124) haltere disc ML-DmD17-c3  (91) eye-antennal disc ML-DmD11  (145) antennal disc ML-DmD20-c5  (169) mixed discs ML-DmD4-c1  (88) CNS ML-DmBG1-c1  (88) CNS ML-DmBG2-c2  (38) tumorous blood cells mbn2  (152) ovary fGS/OSS  (255) ovary OSC  (127) ovary OSS  (116) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4  (246) embryonic 1182-4H  116 embryonic GM2  106 embryonic Kc167    75 embryonic S1    67 embryonic S3  137 leg disc CME L1  (432) wing disc CME-W2  129 wing disc ML-DmD8    78 wing disc ML-DmD9  (178) wing disc ML-DmD16-c3    80 wing disc ML-DmD21  101 wing disc ML-DmD32  124 haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11  (145) antennal disc ML-DmD20-c5  (169) mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2  (152) ovary fGS/OSS  (255) ovary OSC  127 ovary OSS  116 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    246 embryonic 1182-4H    116 embryonic GM2    106 embryonic Kc167    75 embryonic S1    67 embryonic S3    137 leg disc CME L1    432 wing disc CME-W2    129 wing disc ML-DmD8    78 wing disc ML-DmD9    178 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    101 wing disc ML-DmD32    124 haltere disc ML-DmD17-c3    91 eye-antennal disc ML-DmD11    145 antennal disc ML-DmD20-c5    169 mixed discs ML-DmD4-c1    88 CNS ML-DmBG1-c1    88 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    152 ovary fGS/OSS    255 ovary OSC    127 ovary OSS    116 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    180 cold shock, 4-day adult    150 heat shock, 4-day adult    238 Cadmium 50 mM 6 hrs, larvae L3    352 Cadmium 50 mM 12 hrs, larvae L3    842 Cadmium 50 mM 48 hrs, 4-day adult    267 Cadmium 100 mM 48 hrs, 4-day adult    348 Copper 0.5 mM 12 hrs, larvae L3    352 Copper 15 mM 48 hrs, 4-day adult    233 Zinc 5 mM 12 hrs, larvae L3    377 Zinc 4.5 mM 48 hrs, 4-day adult    288 Ethanol 2.5% 3 hrs, larvae L3    186 Ethanol 5% 3 hrs, larvae L3    374 Ethanol 10% 3 hrs, larvae L3    408 Caffeine 1.5 mg/ml 4 hrs, larvae L3    324 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    370 Caffeine 25 mg/ml 48 hrs, 4-day adult    143 Paraquat 5 mM 48 hrs, 4-day adult    126 Paraquat 10 mM 48 hrs, 4-day adult    230 Rotenone 2 μg 12 hrs, larvae L3    433 Rotenone 8 μg 12 hrs, larvae L3    299 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (180) cold shock, 4-day adult  (150) heat shock, 4-day adult  (238) Cadmium 50 mM 6 hrs, larvae L3  (352) Cadmium 50 mM 12 hrs, larvae L3  (842) Cadmium 50 mM 48 hrs, 4-day adult  (267) Cadmium 100 mM 48 hrs, 4-day adult  (348) Copper 0.5 mM 12 hrs, larvae L3  (352) Copper 15 mM 48 hrs, 4-day adult  (233) Zinc 5 mM 12 hrs, larvae L3  (377) Zinc 4.5 mM 48 hrs, 4-day adult  (288) Ethanol 2.5% 3 hrs, larvae L3  (186) Ethanol 5% 3 hrs, larvae L3  (374) Ethanol 10% 3 hrs, larvae L3  (408) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (324) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (370) Caffeine 25 mg/ml 48 hrs, 4-day adult  (143) Paraquat 5 mM 48 hrs, 4-day adult  (126) Paraquat 10 mM 48 hrs, 4-day adult  (230) Rotenone 2 μg 12 hrs, larvae L3  (433) Rotenone 8 μg 12 hrs, larvae L3  (299) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (180) cold shock, 4-day adult  (150) heat shock, 4-day adult  (238) Cadmium 50 mM 6 hrs, larvae L3  (352) Cadmium 50 mM 12 hrs, larvae L3  (842) Cadmium 50 mM 48 hrs, 4-day adult  (267) Cadmium 100 mM 48 hrs, 4-day adult  (348) Copper 0.5 mM 12 hrs, larvae L3  (352) Copper 15 mM 48 hrs, 4-day adult  (233) Zinc 5 mM 12 hrs, larvae L3  (377) Zinc 4.5 mM 48 hrs, 4-day adult  (288) Ethanol 2.5% 3 hrs, larvae L3  (186) Ethanol 5% 3 hrs, larvae L3  (374) Ethanol 10% 3 hrs, larvae L3  (408) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (324) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (370) Caffeine 25 mg/ml 48 hrs, 4-day adult  (143) Paraquat 5 mM 48 hrs, 4-day adult  (126) Paraquat 10 mM 48 hrs, 4-day adult  (230) Rotenone 2 μg 12 hrs, larvae L3  (433) Rotenone 8 μg 12 hrs, larvae L3  (299) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    180 cold shock, 4-day adult    150 heat shock, 4-day adult    238 Cadmium 50 mM 6 hrs, larvae L3    352 Cadmium 50 mM 12 hrs, larvae L3    842 Cadmium 50 mM 48 hrs, 4-day adult    267 Cadmium 100 mM 48 hrs, 4-day adult    348 Copper 0.5 mM 12 hrs, larvae L3    352 Copper 15 mM 48 hrs, 4-day adult    233 Zinc 5 mM 12 hrs, larvae L3    377 Zinc 4.5 mM 48 hrs, 4-day adult    288 Ethanol 2.5% 3 hrs, larvae L3    186 Ethanol 5% 3 hrs, larvae L3    374 Ethanol 10% 3 hrs, larvae L3    408 Caffeine 1.5 mg/ml 4 hrs, larvae L3    324 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    370 Caffeine 25 mg/ml 48 hrs, 4-day adult    143 Paraquat 5 mM 48 hrs, 4-day adult    126 Paraquat 10 mM 48 hrs, 4-day adult    230 Rotenone 2 μg 12 hrs, larvae L3    433 Rotenone 8 μg 12 hrs, larvae L3    299 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    180 cold shock, 4-day adult    150 heat shock, 4-day adult    238 Cadmium 50 mM 6 hrs, larvae L3    352 Cadmium 50 mM 12 hrs, larvae L3    842 Cadmium 50 mM 48 hrs, 4-day adult    267 Cadmium 100 mM 48 hrs, 4-day adult    348 Copper 0.5 mM 12 hrs, larvae L3    352 Copper 15 mM 48 hrs, 4-day adult    233 Zinc 5 mM 12 hrs, larvae L3    377 Zinc 4.5 mM 48 hrs, 4-day adult    288 Ethanol 2.5% 3 hrs, larvae L3    186 Ethanol 5% 3 hrs, larvae L3    374 Ethanol 10% 3 hrs, larvae L3    408 Caffeine 1.5 mg/ml 4 hrs, larvae L3    324 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    370 Caffeine 25 mg/ml 48 hrs, 4-day adult    143 Paraquat 5 mM 48 hrs, 4-day adult    126 Paraquat 10 mM 48 hrs, 4-day adult    230 Rotenone 2 μg 12 hrs, larvae L3    433 Rotenone 8 μg 12 hrs, larvae L3    299 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (180) cold shock, 4-day adult  (150) heat shock, 4-day adult  (238) Cadmium 50 mM 6 hrs, larvae L3  (352) Cadmium 50 mM 12 hrs, larvae L3  (842) Cadmium 50 mM 48 hrs, 4-day adult  (267) Cadmium 100 mM 48 hrs, 4-day adult  (348) Copper 0.5 mM 12 hrs, larvae L3  (352) Copper 15 mM 48 hrs, 4-day adult  (233) Zinc 5 mM 12 hrs, larvae L3  (377) Zinc 4.5 mM 48 hrs, 4-day adult  (288) Ethanol 2.5% 3 hrs, larvae L3  (186) Ethanol 5% 3 hrs, larvae L3  (374) Ethanol 10% 3 hrs, larvae L3  (408) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (324) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (370) Caffeine 25 mg/ml 48 hrs, 4-day adult  (143) Paraquat 5 mM 48 hrs, 4-day adult  (126) Paraquat 10 mM 48 hrs, 4-day adult  (230) Rotenone 2 μg 12 hrs, larvae L3  (433) Rotenone 8 μg 12 hrs, larvae L3  (299) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (180) cold shock, 4-day adult  (150) heat shock, 4-day adult  (238) Cadmium 50 mM 6 hrs, larvae L3  (352) Cadmium 50 mM 12 hrs, larvae L3  (842) Cadmium 50 mM 48 hrs, 4-day adult  (267) Cadmium 100 mM 48 hrs, 4-day adult  (348) Copper 0.5 mM 12 hrs, larvae L3  (352) Copper 15 mM 48 hrs, 4-day adult  (233) Zinc 5 mM 12 hrs, larvae L3  (377) Zinc 4.5 mM 48 hrs, 4-day adult  (288) Ethanol 2.5% 3 hrs, larvae L3  (186) Ethanol 5% 3 hrs, larvae L3  (374) Ethanol 10% 3 hrs, larvae L3  (408) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (324) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (370) Caffeine 25 mg/ml 48 hrs, 4-day adult  143 Paraquat 5 mM 48 hrs, 4-day adult  126 Paraquat 10 mM 48 hrs, 4-day adult  (230) Rotenone 2 μg 12 hrs, larvae L3  (433) Rotenone 8 μg 12 hrs, larvae L3  (299) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    180 cold shock, 4-day adult    150 heat shock, 4-day adult    238 Cadmium 50 mM 6 hrs, larvae L3    352 Cadmium 50 mM 12 hrs, larvae L3    842 Cadmium 50 mM 48 hrs, 4-day adult    267 Cadmium 100 mM 48 hrs, 4-day adult    348 Copper 0.5 mM 12 hrs, larvae L3    352 Copper 15 mM 48 hrs, 4-day adult    233 Zinc 5 mM 12 hrs, larvae L3    377 Zinc 4.5 mM 48 hrs, 4-day adult    288 Ethanol 2.5% 3 hrs, larvae L3    186 Ethanol 5% 3 hrs, larvae L3    374 Ethanol 10% 3 hrs, larvae L3    408 Caffeine 1.5 mg/ml 4 hrs, larvae L3    324 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    370 Caffeine 25 mg/ml 48 hrs, 4-day adult    143 Paraquat 5 mM 48 hrs, 4-day adult    126 Paraquat 10 mM 48 hrs, 4-day adult    230 Rotenone 2 μg 12 hrs, larvae L3    433 Rotenone 8 μg 12 hrs, larvae L3    299 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD37169 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031037 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14207-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG14207 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal CG14207CB02069 viable, with Scer\GAL4pnr-MD237 CG14207GD7609 Phenotype manifest in Allele
Classical Alleles ( 15 )
For All Classical Alleles Show
Allele of CG14207 Class Mutagen Stocks Known lesion CG14207d08767 P-element activity 1 -- CG14207e04363 piggyBac transposase 1 -- CG14207EP766 P-element activity 1 -- CG14207EY02472 P-element activity 1 -- CG14207f01231 piggyBac transposase 1 -- CG14207NP3330 1 -- CG14207CB02069 P-element activity 0 Yes CG14207CPTI003892 piggyBac transposase 0 Yes CG14207CPTI003978 piggyBac transposase 0 Yes CG14207CPTI004445 piggyBac transposase 0 Yes CG14207EP1348 P-element activity 0 -- CG14207f03658 piggyBac transposase 0 -- CG14207f03659 piggyBac transposase 0 -- CG14207G0135a P-element activity 0 -- CG14207MI05262 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG14207 Class Mutagen Stocks Known lesion CG14207GD7609 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes CG14207GD16720 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG14207NIG.14207R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG14207Scer\UAS.T:SV5\V5 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7609} NA P{GD16720} NA P{NIG.14207R} NA P{UAS-CG14207.V5} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG14207EP766 NA P{EP}CG14207EP1348 NA P{EPgy2}CG14207EY02472 NA P{XP}CG14207d08767 NA insertion of enhancer trap binary system P{GawB}CG14207NP3330 No miscellaneous insertions Mi{MIC}CG14207MI05262 NA P{(loxP.en.8)w}1A NA P{PTT-GB}CG14207CB02069 NA PBac{802.P.SVS-2}CG14207CPTI003892 NA PBac{806.LOX-SVS-2}CG14207CPTI003978 NA PBac{810.P.FSVS-2}CG14207CPTI004445 NA PBac{RB}CG14207e04363 NA PBac{WH}CG14207f01231 NA PBac{WH}CG14207f03658 NA PBac{WH}CG14207f03659 NA insertion of enhancer trap P{lacW}CG14207G0135a No
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
NOT protein lipidation inferred from mutant phenotype (Carra et al., 2010) NOT regulation of autophagy inferred from mutant phenotype (Carra et al., 2010) NOT regulation of translational initiation by eIF2 alpha phosphorylation inferred from mutant phenotype (Carra et al., 2010)
Cellular Component
CV term Evidence References
Z disc inferred from direct assay (Arndt et al., 2010)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG14207 - Act79B experimental knowledge based (Guruharsha et al., 2011) CG14207 - Actn experimental knowledge based (Guruharsha et al., 2011) CG14207 - Adh experimental knowledge based (Guruharsha et al., 2011) CG14207 - Ald experimental knowledge based (Guruharsha et al., 2011) CG14207 - Argk experimental knowledge based (Guruharsha et al., 2011) CG14207 - CG10581 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG14207 - CG11777 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - CG5177 experimental knowledge based (Guruharsha et al., 2011) CG14207 - E(spl)m3-HLH anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG14207 - Fer2LCH experimental knowledge based (Guruharsha et al., 2011) CG14207 - Gpdh experimental knowledge based (Guruharsha et al., 2011) CG14207 - Iap2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - Mf experimental knowledge based (Guruharsha et al., 2011) CG14207 - Mhc experimental knowledge based (Guruharsha et al., 2011) CG14207 - Mlc1 experimental knowledge based (Guruharsha et al., 2011) CG14207 - Mlc2 experimental knowledge based (Guruharsha et al., 2011) CG14207 - Obp56d experimental knowledge based (Guruharsha et al., 2011) CG14207 - Prm experimental knowledge based (Guruharsha et al., 2011) CG14207 - Prosβ6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - Scp1 experimental knowledge based (Guruharsha et al., 2011) CG14207 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - Snr1 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG14207 - Spc25 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG14207 - Tm1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - Tm2 experimental knowledge based (Guruharsha et al., 2011) CG14207 - TpnC41C experimental knowledge based (Guruharsha et al., 2011) CG14207 - ct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - h anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - kdn experimental knowledge based (Guruharsha et al., 2011) CG14207 - lolal anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG14207 - p38b experimental knowledge based (Guruharsha et al., 2011) CG14207 - stv anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - up experimental knowledge based (Guruharsha et al., 2011) CG14207 - wbl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG14207 - wupA experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG14207 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59255 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031037 DroID - A comprehensive database of gene and protein interactions. • FBgn0031037 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32955
Orthologs
OrthoDB Orthologs (33) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NKCG2 Dipteran inclusive ortholog search EOG6FN4T6 Insect inclusive ortholog search EOG6BCCJS Arthropod inclusive ortholog search EOG6905SR Metazoa inclusive ortholog search EOG6742MW
Orthologs in Drosophila Species (EOG6NKCG2)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG14207     Drosophila simulans   Dsim\GD24875 Y   Drosophila sechellia   Dsec\GM22970 Y   Drosophila erecta   Dere\GG19234 Y   Drosophila yakuba   Dyak\GE15853 Y   Drosophila ananassae   Dana\GF20408 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA12823 Y   Drosophila persimilis   Dper\GL27055 Y   Drosophila willistoni   Dwil\GK25198 Y   Drosophila virilis   Dvir\GJ15970 Y   Drosophila mojavensis   Dmoj\GI11114 Y   Drosophila grimshawi   Dgri\GH24938 Y
Orthologs in non-Drosophila Dipterans (EOG6FN4T6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001094   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015090   Anopheles gambiae Malaria mosquito  Agam\AGAP000941   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009818
Orthologs in non-Dipteran Insects (EOG6BCCJS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB53550   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005422   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22607   Atta cephalotes Leafcutter ant  Acep\ACEP24193   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15063   Linepithema humile Argentine ant  Lhum\LH19962   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14323   Solenopsis invicta Red fire ant  Sinv\SINV16503   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003907   Bombyx mori Silkmoth  Bmor\Hsp21.4   Pediculus humanus Human body louse  Phum\PHUM217060   Pediculus humanus Human body louse  Phum\PHUM217050   Pediculus humanus Human body louse  Phum\PHUM621170   Tribolium castaneum Red flour beetle  Tcas\TC001152
Orthologs in non-Insect Arthropods (EOG6905SR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_208978   Ixodes scapularis Deer tick  Isca\ISCW017709
Orthologs in non-Arthropod Metazoa (EOG6742MW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\hsp-25
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24875 Drosophila sechellia Dsec\GM22970 Drosophila erecta Dere\GG19234 Drosophila yakuba Dyak\GE15853 Drosophila ananassae Dana\GF20408 Drosophila pseudoobscura pseudoobscura Dpse\GA12823 Drosophila persimilis Dper\GL27055 Drosophila willistoni Dwil\GK25198 Drosophila virilis Dvir\GJ15970 Drosophila mojavensis Dmoj\GI11114 Drosophila grimshawi Dgri\GH24938
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	10147 w1118 P{EP}CG14207EP766 15419 y1 w67c23 P{EPgy2}CG14207EY02472
Harvard	- P{XP}CG14207d08767 - PBac{RB}CG14207e04363 - PBac{WH}CG14207f01231
Kyoto	104456 y* w* P{GawB}CG14207NP3330 / FM7c
VDRC	v31800 w1118; P{GD7609}v31800 v31802 w1118; P{GD7609}v31802 v44831 w1118; P{GD7609}v44831
Genomic Clones ( 2 )
	BACR10M08 BACR33M08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 131 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD37169 RE23625 RE52196
Other clones	DPiM_LD37169 MIP09331 MIP15662
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04972 GH06909 GH16637 GM01633 GM22894 LD14996 LD20210 LD28947 LD28948 LP07232 LP07791 LP10810 LP11742 LP13447 RE02628 RE04531 RE07461 RE07757 RE09468 RE13316 RE17322 RE24927 RE25319 RE28516 RE30069 RE30839 RE31236 RE34835 RE35671 RE40521 RE43927 RE45570 RE46075 RE47540 RE48842 RE52288 RE52296 RE53112 RE53951 RE54788 RE60301 RE66689 RE67054 RE69467 RE70046 RE70327 RE70490 RE71430 RE73637 RE74851 RH51836
Other clones	16119 33987 38555 57756 73160 76255 78257 81359 82555 83101 83688 97307 107666 118244 119951 162154 162473 CK01.7C.C12 CK01.9D.E12 CK01.85A.B4 CK01.87D.D6 CK01.103B.F10 CK01.146B.G8 Dmel_neb_012298_0849_1311 EC23837 EC39844 EC40350 EK067438 EK069347 EK086853 EK120260 EK127061 EK148423 EK151540 EK166214 EK178655 EK201945 EK205947 EK216345 EK216930 EK233514 EK237511 EK265724 EK265940 FGC010H09 FGC012E01 FGH104E01 FGM218H11 RP004024031 RP004087813 RP004095069 RP004125962 RP004197242 RP004206747 RP004208952 RP004215481 RP004242680 RP004243697 RP004248234 RP004261001 RP004322546 RP004346822 RP004355903 RP004370422 RP004375546 RP004395135 RP004400994 RP004421476 RP004477864 RP004480258 RP004488642 RP004508761 RP004512155 RP004530965
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031037 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32955
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	FlyBase Curator comment: Authors of FBrf0209888 say that 'CG14207' is "an uncharacterized fly homolog of [mammalian] HspB8", whereas FBrf0212431 shows there are several candidate genes for being this ortholog and actually conclude that 'Hsp67Bc' ('CG4190') is "the closest functional ortholog of human HSPB8". 'CG14207' has not been given the symbol 'HspB8' for this reason. (Arndt et al., 2010)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134482 NM_167669 NM_001258831 RefSeq (Proteins) • NP_608326 NP_728275 NP_001245760 DDBJ / EMBL / GenBank • AAF48980 AAL28987 AAN09508 AFH07472 AI456979 AQ025353 AW943370 AY061439 BZ748899 CZ476401 CZ482117 CZ483708 CZ483709 CZ486230 CZ486231 CZ486232 CZ486233 Entrez Gene - A searchable database of RefSeq genes. • 32955 UniProtKB/TrEMBL • Q8IQW5 Q9VWG1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Alpha crystallin/Heat shock protein (IPR001436) Alpha crystallin/Hsp20 domain (IPR002068) HSP20-like chaperone (IPR008978) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD37169
Linkouts
	BioGRID - A database of protein and genetic interactions • 59255 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031037 DroID - A comprehensive database of gene and protein interactions. • FBgn0031037 DRSC - Results from RNAi screens. • FBgn0031037 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031037 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14207-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031037 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32955 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32955 modMine - Data generated by the modENCODE project. • FBgn0031037
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG14207 (Zhang et al., 2011, Hartmann et al., 2009, Arndt et al., 2010, Zimmermann et al., 2006, Estrada et al., 2006, Buszczak et al., 2007, Bilen and Bonini, 2007, Tomancak et al., 2007, Carra et al., 2010, Cammarato et al., 2011, Gregory et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Awofala et al., 2012) dHspB8 (Arndt et al., 2010) HspB8 (Arndt et al., 2010)
Name Synonym	HspB8   small heat shock protein hsp20 family (Zou et al., 2000)
Secondary FlyBase IDs
References ( 37 )
Generate a list of	All references relating to this gene ( 37 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 4 )
	Awofala et al., 2012, Funct. Integr. Genomics 12(2): 305--315 Functional roles for redox genes in ethanol sensitivity in Drosophila. [FBrf0218408] Gregory et al., 2012, PLoS ONE 7(2): e31899 The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila. [FBrf0217614] Noyes et al., 2011, G3 (Bethesda) 1(6): 471--478 Modulation of the activity of a polycomb-group response element in Drosophila by a mutation in the transcriptional activator woc. [FBrf0217652] Zhang et al., 2011, J. Molec. Cell. Cardiol. 51(3): 381--389 Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation. [FBrf0214619] Show all research papers ...