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Gene Dmel\CG15618

General Information
Symbol	Dmel\CG15618	Species	D. melanogaster
Name		Annotation symbol	CG15618
Feature type	protein_coding_gene	FlyBase ID	FBgn0031077
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	18F4-18F4	Sequence location	X:19,753,776..19,759,557 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG15618 (FBgn0031077). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF2428, death-receptor-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1631488_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG15618. Gene sequence location is X:19753776..19759557.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 18F4-18F4   Limits computationally determined from genome sequence between P{EP}EP1116&P{EP}EP1344EP1344 and P{EP}amnEP1649&P{EP}amnEP1442
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG15618 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG15618-RB FBtr0289978  NM_134517   5352   1746 CG15618-RC FBtr0308650  NM_001258841   5361   137
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG15618-PB   FBpp0288416   197.4   1746   6.83     NP_608361   AAF49027 CG15618-PC   FBpp0300873   15.6   137   10.53     NP_001245770   AFH07482
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF2428, death-receptor-like (IPR019442)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA694983   AE014298 AAF49027   AE014298 AFH07482   AI533146   AI541769   AI543559   AW944476   AY128504 AAM75097   BG633559   BG639714   BI354032   BI640661   CK661021   GO271016
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VWB9 Q8MQL6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    114.025 Larval Midgut    46.5 Larval Hindgut    52.5 Larval Malpighian Tubules    33.2 Larval Fat Body    33.7 Larval Salivary Gland    99.5 Larval Trachea    89.7 Larval Carcass    65.575 Adult Head    38.2 Adult Eye    29.6 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    44.5 Adult Midgut    40.5 Adult Hindgut    35.2 Adult Malpighian Tubules    32.9 Adult Fat Body    39 Adult Salivary Gland    63.4 Adult Heart    24.775 Adult VirginFemale Spermatheca    44.3 Adult InseminatedFemale Spermatheca    61.6 Adult Ovary    72.3 Adult Testis    18.4 Adult Male Accessory Gland    55.2 Adult Carcass    34.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    38.2   NA  Eye    29.6   NA  Brain    74   114.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    74.9   NA  Crop    44.5   46.5  Midgut    no informative data   52.5  Hindgut    35.2   33.2  Malpighian Tubules    32.9   33.7  Fat Body    39   99.5  Salivary Gland    63.4   NA  Heart    24.775   89.7  Trachea    NA   NA  VirginFemale Spermatheca    44.3   NA  InseminatedFemale Spermatheca    61.6   NA  Ovary    72.3   NA  Testis    no informative data   NA  Male Accessory Gland    55.2   65.575  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    4 central nervous system, pupae P8    2 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    3 embryo 04-06hr    10 embryo 06-08hr    16 embryo 08-10hr    13 embryo 10-12hr    16 embryo 12-14hr    8 embryo 14-16hr    11 embryo 16-18hr    6 embryo 18-20hr    5 embryo 20-22hr    5 embryo 22-24hr    3 larva L1    13 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    5 white prepupae new    5 white prepupae 12hr    5 white prepupae 24hr    8 pupae 2d postWPP    4 pupae 3d postWPP    3 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    3 adult male 30day    4 adult female 01day    8 adult female 05day    8 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    13 embryonic 1182-4H    5 embryonic GM2    10 embryonic Kc167    7 embryonic S1    5 embryonic S3    9 leg disc CME L1    7 wing disc CME-W2    4 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    6 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    6 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    5 ovary fGS/OSS    5 ovary OSC    3 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031077 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15618-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG15618GD9074 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG15618GD9074 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 CG15618GD9074 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG15618GD9074
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG15618 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG15618 Class Mutagen Stocks Known lesion CG15618GD9074 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15618KK100931 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9074} NA P{KK100931} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG15618 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59295 DroID - A comprehensive database of gene and protein interactions. • FBgn0031077 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33001
Orthologs
OrthoDB Orthologs (44) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6JM881 Dipteran inclusive ortholog search EOG69GKQK Insect inclusive ortholog search EOG6VX111 Arthropod inclusive ortholog search EOG6TTDZR Metazoa inclusive ortholog search EOG6ZPSMZ
Orthologs in Drosophila Species (EOG6JM881)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG15618     Drosophila simulans   Dsim\GD15559 Y   Drosophila sechellia   Dsec\GM22702 Y   Drosophila erecta   Dere\GG18019 Y   Drosophila yakuba   Dyak\GE17350 Y   Drosophila ananassae   Dana\GF20221 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13852 Y   Drosophila persimilis   Dper\GL13068 Y   Drosophila willistoni   Dwil\GK25461 Y   Drosophila virilis   Dvir\GJ18663 Y   Drosophila mojavensis   Dmoj\GI15808 Y   Drosophila grimshawi   Dgri\GH19653     Drosophila grimshawi   Dgri\GH11312 Y
Orthologs in non-Drosophila Dipterans (EOG69GKQK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014444   Anopheles gambiae Malaria mosquito  Agam\AGAP010262   Anopheles gambiae Malaria mosquito  Agam\AGAP012629
Orthologs in non-Dipteran Insects (EOG6VX111)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB51040   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000517   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22626   Atta cephalotes Leafcutter ant  Acep\ACEP12417   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15419   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19591   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19590   Linepithema humile Argentine ant  Lhum\LH24537   Pogonomyrmex barbatus Red harvester ant  Pbar\PB24621   Solenopsis invicta Red fire ant  Sinv\SINV24977   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008183   Bombyx mori Silkmoth  Bmor\BGIBMGA008289   Bombyx mori Silkmoth  Bmor\BGIBMGA008290   Bombyx mori Silkmoth  Bmor\BGIBMGA008288   Pediculus humanus Human body louse  Phum\PHUM095870   Tribolium castaneum Red flour beetle  Tcas\TC004365
Orthologs in non-Insect Arthropods (EOG6TTDZR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\ipo7   Ixodes scapularis Deer tick  Isca\ISCW003997   Ixodes scapularis Deer tick  Isca\ISCW006321
Orthologs in non-Arthropod Metazoa (EOG6ZPSMZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y92H12A.5   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001263gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018549gn   Danio rerio Zebrafish  Drer\ENSDARG00000053082   Xenopus tropicalis Western clawed frog  Xtro\thada   Gallus gallus Domestic chicken  Ggal\THADA   Mus musculus House mouse  Mmus\Thada   Rattus norvegicus Norway rat  Rnor\Thada   Homo sapiens Human  Hsap\THADA
Human Orthologs (1)
Gene OMIM HGNC Hsap\THADA
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15559 Drosophila sechellia Dsec\GM22702 Drosophila erecta Dere\GG18019 Drosophila yakuba Dyak\GE17350 Drosophila ananassae Dana\GF20221 Drosophila pseudoobscura pseudoobscura Dpse\GA13852 Drosophila persimilis Dper\GL13068 Drosophila willistoni Dwil\GK25461 Drosophila virilis Dvir\GJ18663 Drosophila mojavensis Dmoj\GI15808 Drosophila grimshawi Dgri\GH11312
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v108285 P{KK100931}VIE-260B v40006 w1118; P{GD9074}v40006
Genomic Clones ( 1 )
	BACR48P17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 8 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD06922
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM26028 LP20089 SD10353 SD23622
Other clones	DMG7-chrX.35.005.pred.a GM01893 SD04871
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031077 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33001
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134517 NM_001258841 RefSeq (Proteins) • NP_608361 NP_001245770 DDBJ / EMBL / GenBank • AAF49027 AAM75097 AFH07482 AI541769 AW944476 AY128504 Entrez Gene - A searchable database of RefSeq genes. • 33001 UniProtKB/TrEMBL • Q8MQL6 Q9VWB9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF2428, death-receptor-like (IPR019442)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59295 DroID - A comprehensive database of gene and protein interactions. • FBgn0031077 DRSC - Results from RNAi screens. • FBgn0031077 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031077 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15618-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031077 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33001 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33001 modMine - Data generated by the modENCODE project. • FBgn0031077
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG15618 (Keleman et al., 2009.8.5, Wasbrough et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Research paper	Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wasbrough et al., 2010, J. Proteomics 73(11): Supplemental Table 1. Mass spectrometry data. [FBrf0213252] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Mount, 2001.8.14, Intron annotations. Intron annotations. [FBrf0137489] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
DNA/RNA sequence record	Thornton, 2005.12.20, GenBank/EMBL/DDBJ: DQ334106 Drosophila miranda CG15618 gene, partial cds. [FBrf0197714]