DmRab35, dRab35
tissue polarity, an essential component of the contractile process that functions as a membrane ratchet to ensure unidirectional movement of intercalating cells - gastrulation - mesoderm invagination - Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth during tracheal development - Skywalker facilitates endosomal trafficking of synaptic vesicles at NMJ boutons by controlling Rab35 activity
Please see the JBrowse view of Dmel\Rab35 for information on other features
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rab35 using the Feature Mapper tool.
Comment: maternally deposited
Comment: 30-40h APF
Comment: 30-40h APF
Comment: 30-40h APF
GBrowse - Visual display of RNA-Seq signals
View Dmel\Rab35 in GBrowse 21-64
1-63.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
A large increase in the proportion of binucleated cells is seen following transfection of S2 cells with dsRNA made from templates generated with primers directed against this gene.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: binucleate cells.