• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG9581

General Information
Symbol	Dmel\CG9581	Species	D. melanogaster
Name		Annotation symbol	CG9581
Feature type	protein_coding_gene	FlyBase ID	FBgn0031093
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	19C1-19C1	Sequence location	X:20,062,075..20,064,013 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9581 (FBgn0031093). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis; cellular process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase M24, methionine aminopeptidase; Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval midgut, larval hindgut, adult heart, larval/adult salivary gland, adult ovary, adult male reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631213_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9581. Gene sequence location is X:20062075..20064013.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA20695 BKN22514
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 19C1-19C1   Limits computationally determined from genome sequence between P{EP}amnEP1639&P{EP}amnEP367 and P{EP}CG1702EP1525
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9581 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9581-RA FBtr0070026  NM_134532   1882   545
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9581-PA   FBpp0070025   60.9   545   6.89     NP_608376   AAF45368
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M24, structural domain (IPR000994) Peptidase M24, methionine aminopeptidase (IPR001714) Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal (IPR007865)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201851   AA696119   AA820196   AA940903   AA942217   AA951325   AE014298 AAF45368   AI258891   AI388140   AI388541   AI517584   AI519518   AI519724   AW940740   AY069164 AAL39309   BE978741   BF486706   BF487445   BF489008   BF491228   BF491962   BF496331   BF501320   BF501323   BF503085   BF505934   BF506460   BI141967   BI230013   BI231302   BI239017   BP555595   CK658384   CO178136   CO186370   CO191769   CO282080   CO286095   CO287255   CO344694   EC051180   EC051730   EC052183   EC054706   EC055141   EC068380   EC194608   EC217005   EC218740   EC230175   EC230176   EC252620   EL874140   EL874141   EL874265   EL874266   EL874374   EL883287   EL883288
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W5W7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031093    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031093 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031093 expression level Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3473) embryo 02-04hr  (3141) embryo 04-06hr  (1411) embryo 06-08hr  (1342) embryo 08-10hr  (1494) embryo 10-12hr  (1792) embryo 12-14hr  (956) embryo 14-16hr  (1677) embryo 16-18hr  (1186) embryo 18-20hr  (1101) embryo 20-22hr  (889) embryo 22-24hr  (640) larva L1  (1737) larva L2  (1814) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1139) larva L3 puffstage 3-6  (1298) larva L3 puffstage 7-9  (1201) white prepupae new  (1017) white prepupae 12hr  (1240) white prepupae 24hr  (1643) pupae 2d postWPP  (1951) pupae 3d postWPP  (1984) pupae 4d postWPP  (2585) adult male 01day  (3200) adult male 05day  (4505) adult male 30day  (4873) adult female 01day  (2149) adult female 05day  (1898) adult female 30day  (2335) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3473) embryo 02-04hr  (3141) embryo 04-06hr  1411 embryo 06-08hr    1342 embryo 08-10hr  1494 embryo 10-12hr  (1792) embryo 12-14hr    956 embryo 14-16hr  (1677) embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1  (1737) larva L2  (1814) larva L3 12hr old  (1589) larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr  (1643) pupae 2d postWPP  (1951) pupae 3d postWPP  (1984) pupae 4d postWPP  (2585) adult male 01day  (3200) adult male 05day  (4505) adult male 30day  (4873) adult female 01day  (2149) adult female 05day  (1898) adult female 30day  (2335) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031093 expression level Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3473) embryo 02-04hr  (3141) embryo 04-06hr  (1411) embryo 06-08hr  (1342) embryo 08-10hr  (1494) embryo 10-12hr  (1792) embryo 12-14hr  (956) embryo 14-16hr  (1677) embryo 16-18hr  (1186) embryo 18-20hr  (1101) embryo 20-22hr  (889) embryo 22-24hr  (640) larva L1  (1737) larva L2  (1814) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1139) larva L3 puffstage 3-6  (1298) larva L3 puffstage 7-9  (1201) white prepupae new  (1017) white prepupae 12hr  (1240) white prepupae 24hr  (1643) pupae 2d postWPP  (1951) pupae 3d postWPP  (1984) pupae 4d postWPP  (2585) adult male 01day  (3200) adult male 05day  (4505) adult male 30day  (4873) adult female 01day  (2149) adult female 05day  (1898) adult female 30day  (2335) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3473) embryo 02-04hr  (3141) embryo 04-06hr  1411 embryo 06-08hr    1342 embryo 08-10hr  1494 embryo 10-12hr  1792 embryo 12-14hr    956 embryo 14-16hr  1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1  1737 larva L2  1814 larva L3 12hr old  1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr  1643 pupae 2d postWPP  1951 pupae 3d postWPP  1984 pupae 4d postWPP  (2585) adult male 01day  (3200) adult male 05day  (4505) adult male 30day  (4873) adult female 01day  2149 adult female 05day  1898 adult female 30day  2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3473 embryo 02-04hr    3141 embryo 04-06hr    1411 embryo 06-08hr    1342 embryo 08-10hr    1494 embryo 10-12hr    1792 embryo 12-14hr    956 embryo 14-16hr    1677 embryo 16-18hr    1186 embryo 18-20hr    1101 embryo 20-22hr    889 embryo 22-24hr    640 larva L1    1737 larva L2    1814 larva L3 12hr old    1589 larva L3 puffstage 1-2    1139 larva L3 puffstage 3-6    1298 larva L3 puffstage 7-9    1201 white prepupae new    1017 white prepupae 12hr    1240 white prepupae 24hr    1643 pupae 2d postWPP    1951 pupae 3d postWPP    1984 pupae 4d postWPP    2585 adult male 01day    3200 adult male 05day    4505 adult male 30day    4873 adult female 01day    2149 adult female 05day    1898 adult female 30day    2335 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031093    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031093 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval midgut, larval hindgut, adult heart, larval/adult salivary gland, adult ovary, adult male reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031093 expression level Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031093 expression level Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.975 Larval Midgut    137.8 Larval Hindgut    138.2 Larval Malpighian Tubules    74.4 Larval Fat Body    87.3 Larval Salivary Gland    129.2 Larval Trachea    73.65 Larval Carcass    88.3 Adult Head    73.5 Adult Eye    55.1 Adult Brain    118.8 Adult Thoracic-Abdominal Ganglion    145.8 Adult Crop    105 Adult Midgut    90 Adult Hindgut    87.5 Adult Malpighian Tubules    70.1 Adult Fat Body    78.3 Adult Salivary Gland    104 Adult Heart    100.15 Adult VirginFemale Spermatheca    63.4 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    122.7 Adult Testis    315 Adult Male Accessory Gland    105 Adult Carcass    107.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    73.5   NA  Eye    55.1   NA  Brain    118.8   163.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    145.8   NA  Crop    105   137.8  Midgut    90   138.2  Hindgut    87.5   74.4  Malpighian Tubules    70.1   87.3  Fat Body    78.3   129.2  Salivary Gland    104   NA  Heart    100.15   73.65  Trachea    NA   NA  VirginFemale Spermatheca    63.4   NA  InseminatedFemale Spermatheca    76.7   NA  Ovary    122.7   NA  Testis    315   NA  Male Accessory Gland    105   88.3  Carcass    107.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031093 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9581-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG9581 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG9581GD14257 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG9581 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9581 Class Mutagen Stocks Known lesion CG9581GD16799 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG9581GD14257 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9581HMS01018 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9581KK102433 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14257} NA P{GD16799} NA P{KK102433} NA P{TRiP.HMS01018} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
aminopeptidase activity inferred from sequence or structural similarity with EMBL:AC006416 (FlyBase, 1992-) manganese ion binding inferred from electronic annotation with InterPro:IPR007865 (FlyBase Curators et al., 2004-) metalloexopeptidase activity inferred from electronic annotation with InterPro:IPR001714 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
cellular process inferred from electronic annotation with InterPro:IPR000994 (FlyBase Curators et al., 2004-) proteolysis inferred from electronic annotation with InterPro:IPR001714 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9581 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59310 DroID - A comprehensive database of gene and protein interactions. • FBgn0031093 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33017
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20449 Dere\GG18008 Dgri\GH12088 Dmoj\GI11096 Dper\GL12918 Dpse\GA21891 Dvir\GJ15780 Dwil\GK25597 Dyak\GE17339
Curated drosophilid orthologs	Dpse\GA21891
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL003591-PA Aedes aegypti (mosquito) AAEL010960-PA Aedes aegypti (mosquito) AGAP000887-PA Anopheles gambiae (mosquito) XP_001944476.1 Acyrthosiphon pisum (pea aphid) At1g09300.1 Arabidopsis thaliana (wall cress) 19533 Batrachochytrium dendrobatidis (chytrid fungus) 125585 Branchiostoma floridae (lancelet) XP_001899815.1 Brugia malayi (roundworm nematode) BGIBMGA007934-PA Bombyx mori (silk worm) ENSBTAP00000008149 Bos taurus (bovine) CAL0004826 Candida albicans (a form of yeast) CE34356 Caenorhabditis elegans (worm) ENSCAFP00000001595 Canis familiaris (dog) CAGL0J03300g Candida glabrata (haploid yeast) ENSCINP00000010780 Ciona intestinalis (sea squirt) CMA107C Cyanidioschyzon merolae (red alga) cn03155 Cryptococcus neoformans (yeast-like fungus) CPIJ009004 Culex pipens (mosquito) ENSCPOP00000002082 Cavia porcellus (guinea pig) RP32463 Caenorhabditis remanei (nematode) 172665 Capitella spl (polychaete worm) DDB0218347 Dictyostelium discoideum (amoeba) DEHA2B13750g Debaryomyces Hansenii (yeast) 308500 Daphnia pulex (daphnia) ENSDARP00000050244 Danio rerio (zebra fish) ENSECAP00000016082 Equus caballus (horse) NP_417384.1 Escherichia coli K12 (bacteria) ENSGACP00000010203 Gymnopilus aculeatus (mushroom) ENSGALP00000019563 Gallus gallus (chicken) 186061 Hypsipyla robusta (cedar shoot borer) ENSP00000349658 Homo sapiens (human) ISCW008932-PA Ixodes scapularis (deer tick) KLLA0C07645g Kluyveromyces lactis (yeast) 182228 Lottia gigantea (owl limpet) 37508 Monocosta brevicollis (choanoflagellate) ENSMODP00000016332 Monodelphis domestica (gray opossum) ENSMMUP00000005437 Macaca mulatta (rhesus monkey) ENSMUSP00000038331 Mus musculus (house mouse) 173148 Nematostella vectensis (starlet anemone) XP_001605691.1 Nasonia vitripennis (wasp) ENSOANP00000023128 Ornithorynchus anatinus (platypus) ENSORLP00000017560 Oryzias latipes (japanese killifish) LOC_Os12g37640.1 Oryza sativa (asian rice) 15272 Ostreococcus tauri (green alga) PHUM001586-PA Pediculus humanus (human body louse) 131941 Physcomitrella patens (moss) ENSPPYP00000013233 Pongo pygmaeus (orangutan) 79742 Phytophthora ramorum (sudden oak death pathogen) 108328 Phytophthora sojae (root rot pathogen) 570698 Populus trichocarpa (black cottonwood) ENSPTRP00000024836 Pan troglodytes (chimpanzee) ENSRNOP00000030355 Rattus norvegicus (norway rat) 4766150 Sorghum bicolor (sorghum) YER078C Saccharomyces cerevisiae (budding yeast) SPAC12B10.05 Schizosaccharomyces pombe (fission yeast) XP_001204314.1 Strongylocentrotus purpuratus (purple sea urchin) 21089 Trichoplax adhaerens (metazoa) XP_968082.2 Tribolium castaneum (red flour beetle) ENSTNIP00000007761 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000018329 Takifugu rubripes (pufferfish Takifugu) 87912.m00130 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000049688 Xenopus tropicalis (frog) YALI0B20394g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11179 LH19614 ISCW008932 FBgn0234810 FBgn0227556 FBgn0202968 FBgn0177559 FBgn0177558 JGI_V11_308500 FBgn0081876 FBgn0150524 FBgn0133858 FBgn0119567 FBgn0110226 FBgn0097456 CPIJ009004 BGIBMGA007934 ACYPI008902 GB11289 AGAP000887 AAEL010960 AAEL003591 PB24395 PHUM318560 GLEAN_16224
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	34547 y1 sc* v1; P{TRiP.HMS01018}attP2
VDRC	v105150 P{KK102433}VIE-260B v39208 w1118; P{GD14257}v39208 v48221 w1118; P{GD16799}v48221 v48220 w1118; P{GD16799}v48220/CyO
Genomic Clones ( 1 )
	BACR11H15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 53 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH19483
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08263 AT08935 AT10103 AT16609 AT16612 AT18991 AT21207 AT22244 AT24692 AT27925 AT28821 GH18940 GH28592 GM05102 LD03768 LD23233 LD23682 LD26304 LD31733 LD39139 LD39431 LP02189 LP15271 RE20750 RE27930 RE35396 SD15947
Other clones	214447.63 bs82d02 CK01.2A.E5 CK01.20A.G8 CK01.69B.D2 CK01.69B.D4 CK01.79C.D5 CK01.112D.D7 EC31786 EC051180 EC051730 EC052183 EC054706 EC055141 EK019043 EK055445 EK061715 EK065335 EK159503 EP19735 FGM236B03 IP12978 IP14189 IP14289 IP14389
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031093 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33017
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134532 RefSeq (Proteins) • NP_608376 DDBJ / EMBL / GenBank • AAF45368 AAL39309 AI388541 AW940740 AY069164 Entrez Gene - A searchable database of RefSeq genes. • 33017 UniProtKB/TrEMBL • Q9W5W7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M24, structural domain (IPR000994) Peptidase M24, methionine aminopeptidase (IPR001714) Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal (IPR007865)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59310 DroID - A comprehensive database of gene and protein interactions. • FBgn0031093 DRSC - Results from RNAi screens. • FBgn0031093 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031093 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9581-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031093 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33017 InParanoid A subset of ortholog calls from InParanoid. • AAEL003591-PA Aedes aegypti (mosquito) AAEL010960-PA Aedes aegypti (mosquito) AGAP000887-PA Anopheles gambiae (mosquito) XP_001944476.1 Acyrthosiphon pisum (pea aphid) At1g09300.1 Arabidopsis thaliana (wall cress) 19533 Batrachochytrium dendrobatidis (chytrid fungus) 125585 Branchiostoma floridae (lancelet) XP_001899815.1 Brugia malayi (roundworm nematode) BGIBMGA007934-PA Bombyx mori (silk worm) ENSBTAP00000008149 Bos taurus (bovine) CAL0004826 Candida albicans (a form of yeast) CE34356 Caenorhabditis elegans (worm) ENSCAFP00000001595 Canis familiaris (dog) CAGL0J03300g Candida glabrata (haploid yeast) ENSCINP00000010780 Ciona intestinalis (sea squirt) CMA107C Cyanidioschyzon merolae (red alga) cn03155 Cryptococcus neoformans (yeast-like fungus) CPIJ009004 Culex pipens (mosquito) ENSCPOP00000002082 Cavia porcellus (guinea pig) RP32463 Caenorhabditis remanei (nematode) 172665 Capitella spl (polychaete worm) DDB0218347 Dictyostelium discoideum (amoeba) DEHA2B13750g Debaryomyces Hansenii (yeast) 308500 Daphnia pulex (daphnia) ENSDARP00000050244 Danio rerio (zebra fish) ENSECAP00000016082 Equus caballus (horse) NP_417384.1 Escherichia coli K12 (bacteria) ENSGACP00000010203 Gymnopilus aculeatus (mushroom) ENSGALP00000019563 Gallus gallus (chicken) 186061 Hypsipyla robusta (cedar shoot borer) ENSP00000349658 Homo sapiens (human) ISCW008932-PA Ixodes scapularis (deer tick) KLLA0C07645g Kluyveromyces lactis (yeast) 182228 Lottia gigantea (owl limpet) 37508 Monocosta brevicollis (choanoflagellate) ENSMODP00000016332 Monodelphis domestica (gray opossum) ENSMMUP00000005437 Macaca mulatta (rhesus monkey) ENSMUSP00000038331 Mus musculus (house mouse) 173148 Nematostella vectensis (starlet anemone) XP_001605691.1 Nasonia vitripennis (wasp) ENSOANP00000023128 Ornithorynchus anatinus (platypus) ENSORLP00000017560 Oryzias latipes (japanese killifish) LOC_Os12g37640.1 Oryza sativa (asian rice) 15272 Ostreococcus tauri (green alga) PHUM001586-PA Pediculus humanus (human body louse) 131941 Physcomitrella patens (moss) ENSPPYP00000013233 Pongo pygmaeus (orangutan) 79742 Phytophthora ramorum (sudden oak death pathogen) 108328 Phytophthora sojae (root rot pathogen) 570698 Populus trichocarpa (black cottonwood) ENSPTRP00000024836 Pan troglodytes (chimpanzee) ENSRNOP00000030355 Rattus norvegicus (norway rat) 4766150 Sorghum bicolor (sorghum) YER078C Saccharomyces cerevisiae (budding yeast) SPAC12B10.05 Schizosaccharomyces pombe (fission yeast) XP_001204314.1 Strongylocentrotus purpuratus (purple sea urchin) 21089 Trichoplax adhaerens (metazoa) XP_968082.2 Tribolium castaneum (red flour beetle) ENSTNIP00000007761 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000018329 Takifugu rubripes (pufferfish Takifugu) 87912.m00130 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000049688 Xenopus tropicalis (frog) YALI0B20394g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33017 modMine - Data generated by the modENCODE project. • FBgn0031093 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11179 LH19614 ISCW008932 FBgn0234810 FBgn0227556 FBgn0202968 FBgn0177559 FBgn0177558 JGI_V11_308500 FBgn0081876 FBgn0150524 FBgn0133858 FBgn0119567 FBgn0110226 FBgn0097456 CPIJ009004 BGIBMGA007934 ACYPI008902 GB11289 AGAP000887 AAEL010960 AAEL003591 PB24395 PHUM318560 GLEAN_16224
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG9581 (Keleman et al., 2009.8.5, Spresser et al., 2008, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Spresser et al., 2008, J. Genet. 87(2): 109--117 Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity. [FBrf0205982]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Gong, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126669]