FlyBase Gene Report: Dmel\obst-A

General Information

Symbol

Dmel\obst-A

Species

D. melanogaster

Name

obstructor-A

Annotation Symbol

CG17052

Feature Type

protein_coding_gene

FlyBase ID

FBgn0031097

Gene Model Status

Current

Stock Availability

3 publicly available

Gene Snapshot

obstructor-A (obst-A) encodes a protein that forms a core complex with chitin and the chitin modifying proteins encoded by serp and knk. This complex is required for assembly, maturation and preservation of the chitinous cuticles at the end of embryogenesis and probably throughout larval development. [Date last reviewed: 2019-03-14]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

19C1-19C1

Sequence location

X:20,239,855..20,243,209 [+]

Recombination map

1-64

RefSeq locus

NC_004354 REGION:20239855..20243209

Sequence

Get Decorated FASTA

Genomic Maps

GBrowse JBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

[Detailed GO annotations]

Gene Group (FlyBase)

OBSTRUCTOR FAMILY

CHITIN BINDING DOMAIN-CONTAINING PROTEINS

Protein Family (UniProt)

Protein Signatures (InterPro)

Molecular Function (GO)
[Detailed GO annotations]

Experimental Evidence

chitin binding; structural constituent of chitin-based cuticle

Predictions / Assertions

Summaries

Gene Group (FlyBase)

OBSTRUCTOR FAMILY -: The Obstructor family encode secreted proteins with three chitin binding domains. Members of this family are involved in cuticle organisation. (Adapted from FBrf0190484 and FBrf0234504.)
CHITIN BINDING DOMAIN-CONTAINING PROTEINS -: Chitin binding domains are found in certain classes of chitin binding proteins and chitin-active enzymes. (Adapted from FBrf0108362.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\obst-A or the JBrowse view of Dmel\obst-A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.50

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

obst-A-RA

FBtr0077334

NM_134534

1905

237

obst-A-RB

FBtr0306737

NM_001258849

1235

237

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

obst-A-PA

FBpp0077026

26.6

237

4.38

NP_608378

AAF50927

obst-A-PB

FBpp0297663

26.6

237

4.38

NP_001245778

AFH07490

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

237 aa isoforms: obst-A-PA, obst-A-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VR79

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\obst-A using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Gene Ontology (8 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

chitin binding

inferred from direct assay

(Petkau et al., 2012)

structural constituent of chitin-based cuticle

inferred from direct assay

(Pesch et al., 2015, Petkau et al., 2012)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (5 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

chitin-based cuticle development

inferred from mutant phenotype

(Tiklová et al., 2013, Petkau et al., 2012)

larval chitin-based cuticle development

inferred from mutant phenotype

(Pesch et al., 2015)

negative regulation of extracellular matrix disassembly

inferred from mutant phenotype

(Petkau et al., 2012)

regulation of tube size, open tracheal system

inferred from mutant phenotype

(Tiklová et al., 2013)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

chitin metabolic process

inferred from electronic annotation with InterPro:IPR002557

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

chitin-based extracellular matrix

inferred from direct assay

(Pesch et al., 2015, Tiklová et al., 2013, Petkau et al., 2012)

Terms Based on Predictions or Assertions (0 terms)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

anterior spiracle primordium

Comment: reported as anterior spiracle specific anlage

(Fisher et al., 2012)

dorsal trunk primordium

Comment: reported as dorsal trunk specific anlage

(Fisher et al., 2012)

posterior spiracle primordium

Comment: reported as posterior spiracle specific anlage

(Fisher et al., 2012)

primary segmental branch primordium

Comment: reported as primary segmental branch specific anlage

(Fisher et al., 2012)

tracheal primordium

(Fisher et al., 2012)

visceral branch primordium

Comment: reported as visceral branch specific anlage

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic epipharynx

(Fisher et al., 2012)

embryonic head epidermis

(Fisher et al., 2012)

embryonic hypopharynx

(Fisher et al., 2012)

embryonic/larval dorsal branch

(Fisher et al., 2012)

embryonic/larval dorsal trunk

(Fisher et al., 2012)

embryonic/larval posterior spiracle

(Fisher et al., 2012)

embryonic/larval visceral branch

(Fisher et al., 2012)

embryonic stage 14 -- 17

embryonic/larval tracheal system

(Petkau et al., 2012)

embryonic/larval hindgut

(Petkau et al., 2012)

embryonic/larval foregut

(Petkau et al., 2012)

embryonic/larval proventriculus

(Petkau et al., 2012)

embryonic/larval posterior spiracle

(Petkau et al., 2012)

embryonic stage 16 -- 17

embryonic/larval epidermis

(Petkau et al., 2012)

embryonic stage 13 -- 17

embryonic/larval trachea

(Tiklová et al., 2013)

embryonic stage 12 -- 16

embryonic/larval trachea

(Chung et al., 2011)

Additional Descriptive Data

obst-A expression is observed from embryonic stage 14 on in the tracheal system, foregut (including proventriculus and posterior spiracles), and in the hindgut. Epidermal expression starts at embryonic stage 16.

(Petkau et al., 2012)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 14 -- 17

embryonic/larval tracheal system

(Petkau et al., 2012)

embryonic/larval hindgut

(Petkau et al., 2012)

embryonic/larval foregut

(Petkau et al., 2012)

embryonic/larval proventriculus

(Petkau et al., 2012)

embryonic/larval posterior spiracle

(Petkau et al., 2012)

embryonic stage 16 -- 17

embryonic/larval epidermis

(Petkau et al., 2012)

Additional Descriptive Data

(Petkau et al., 2012)

Marker for

Subcellular Localization

CV Term

Evidence

References

chitin-based extracellular matrix

inferred from direct assay

(Pesch et al., 2015, Tiklová et al., 2013, Petkau et al., 2012)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\obst-A in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\obst-A

View exonic expression by tissue for Dmel\obst-A

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031097

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0031097

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG17052-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17052

Flygut - An atlas of the Drosophila adult midgut

FBgn0031097

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\obst-A

Stages(s) 4-6
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of obst-A

Transgenic constructs containing regulatory region of obst-A

Deletions and Duplications ( 1 )

Disrupted in

Df(1)HM44

(Petkau et al., 2012)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

obst-A⁶⁶³

lethal - all die before end of larval stage | recessive

lethal - all die during larval stage

obst-A^Δ1

partially lethal - majority die, with Scer\GAL4^pnr-MD237

obst-A^GD4857

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

obst-A^GD4857

viable, with Scer\GAL4^Mef2.PR

obst-A^GD4857

Other Phenotypes

Allele

small body

obst-A⁶⁶³

small body | larval stage | recessive

obst-A^Δ1

some die during larval stage | recessive

some die during pupal stage, with Scer\GAL4^pnr-MD237

obst-A^GD4857

visible, with Scer\GAL4^pnr-MD237

obst-A^GD4857

Phenotype manifest in

Allele

cuticle

obst-A^unspecified

embryonic/first instar larval cuticle

embryonic/larval dorsal trunk | embryonic stage

obst-A^Δ1

embryonic/larval tracheal system

taenidial fold

obst-A^unspecified

trichogen cell, with Scer\GAL4^pnr-MD237

obst-A^GD4857

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (0)

No records found.

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (0)

No records found.

Rattus norvegicus (Norway rat) (0)

No records found.

Xenopus tropicalis (Western clawed frog) (0)

No records found.

Danio rerio (Zebrafish) (0)

No records found.

Caenorhabditis elegans (Nematode, roundworm) (4)

Cele\C39D10.7

2 of 15

Yes

Cele\cpg-2

2 of 15

Yes

Cele\R02F2.4

2 of 15

Yes

Cele\cbd-1

1 of 15

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190D9U )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14300

Drosophila persimilis

Dper\GL13082

Drosophila willistoni

Dwil\GK25193

Drosophila virilis

Dvir\GJ15813

Drosophila mojavensis

Dmoj\GI11032

Drosophila grimshawi

Dgri\GH12617

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915071V )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17011588

Musca domestica

House fly

Mdoa\17018673

Glossina morsitans

Tsetse fly

Gmor\GMOY009572

Glossina morsitans

Tsetse fly

Gmor\GMOY004893

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_10455

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_14048

Mayetiola destructor

Hessian fly

Mdes\Mdes014737

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL013222

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL012245

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL009577

Anopheles darlingi

American malaria mosquito

Adar\ADAC003739

Anopheles darlingi

American malaria mosquito

Adar\ADAC003744

Anopheles gambiae

Malaria mosquito

Agam\CPAP3-B

Anopheles gambiae

Malaria mosquito

Agam\CPAP3-A1c

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000680

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000679

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006133

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0DQ1 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA007899

Bombyx mori

Silkmoth

Bmor\Bmo.1741

Bombyx mori

Silkmoth

Bmor\BGIBMGA007678

Bombyx mori

Silkmoth

Bmor\BGIBMGA007901

Danaus plexippus

Monarch butterfly

Dple\DPOGS213061-PA

Danaus plexippus

Monarch butterfly

Dple\DPOGS213142-PA

Danaus plexippus

Monarch butterfly

Dple\DPOGS213141-PA

Danaus plexippus

Monarch butterfly

Dple\DPOGS213140-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL010346

Heliconius melpomene

Postman butterfly

Hmel\HMEL010347

Heliconius melpomene

Postman butterfly

Hmel\HMEL010348

Heliconius melpomene

Postman butterfly

Hmel\HMEL010349

Apis florea

Little honeybee

Aflo\2341655300

Apis florea

Little honeybee

Aflo\5578430180

Apis florea

Little honeybee

Aflo\2159461636

Apis florea

Little honeybee

Aflo\2341655108

Apis mellifera

Western honey bee

Amel\Cpap3-d

Apis mellifera

Western honey bee

Amel\Cpap3-b

Apis mellifera

Western honey bee

Amel\GB41945

Apis mellifera

Western honey bee

Amel\GB50636

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP24007

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP23982

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP24006

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP23981

Bombus terrestris

Buff-tailed bumblebee

Bter\15215281

Bombus terrestris

Buff-tailed bumblebee

Bter\15215280

Bombus terrestris

Buff-tailed bumblebee

Bter\15215229

Bombus terrestris

Buff-tailed bumblebee

Bter\15215228

Linepithema humile

Argentine ant

Lhum\LH18883

Linepithema humile

Argentine ant

Lhum\LH18878

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:000b80

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001fbc

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG036941

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG000845

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG000848

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG000844

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_04719

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_04720

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_04722

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_11656

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_04721

Tribolium castaneum

Red flour beetle

Tcas\CPAP3-D1

Tribolium castaneum

Red flour beetle

Tcas\Obst-B

Tribolium castaneum

Red flour beetle

Tcas\CPAP3-A1

Tribolium castaneum

Red flour beetle

Tcas\CPAP3-A2

Pediculus humanus

Human body louse

Phum\PHUM434570

Pediculus humanus

Human body louse

Phum\PHUM434540

Pediculus humanus

Human body louse

Phum\PHUM434550

Rhodnius prolixus

Kissing bug

Rpro\RPRC010253

Rhodnius prolixus

Kissing bug

Rpro\RPRC010254

Rhodnius prolixus

Kissing bug

Rpro\RPRC010255

Cimex lectularius

Bed bug

Clec\CLEC008702

Cimex lectularius

Bed bug

Clec\CLEC007794

Cimex lectularius

Bed bug

Clec\CLEC008703

Cimex lectularius

Bed bug

Clec\CLEC025275

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI007911

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI004093

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI006031

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI009786

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05889

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05888

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05892

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05890

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0DO1 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR007307

Ixodes scapularis

Black-legged tick

Isca\ISCW024120

Ixodes scapularis

Black-legged tick

Isca\ISCW013029

Ixodes scapularis

Black-legged tick

Isca\ISCW011513

Stegodyphus mimosarum

African social velvet spider

Smim\KFM69986.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM71245.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM66346.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM79683.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur06g01550

Tetranychus urticae

Two-spotted spider mite

Turt\tetur27g00090

Tetranychus urticae

Two-spotted spider mite

Turt\tetur19g00240

Tetranychus urticae

Two-spotted spider mite

Turt\tetur15g01480

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_303616

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_93732

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_333110

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_230004

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0LTG )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Hypp_271

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Hypp_1196

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_024915gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_018580gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_021957gn

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000016289

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000005255

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000023680

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000016282

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (42)

Gene Symbol

Score

Source

Alignment

3 of 10

3 of 10

3 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

obst-A - knk

pull down, western blot

(Petkau et al., 2012)

obst-A - serp

pull down, western blot

(Petkau et al., 2012)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

obst-A

enhanceable

Gasp

(Tiklová et al., 2013)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Gasp

enhanceable

obst-A

(Tiklová et al., 2013)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0031097

MIST (protein-protein) - An integrated Molecular Interaction Database

obst-A

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-64

Cytogenetic map

19C1-19C1

Sequence location

X:20,239,855..20,243,209 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

19C1-19C1

Limits computationally determined from genome sequence between P{EP}amn^EP1639&P{EP}amn^EP367 and P{EP}CG1702^EP1525

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-64

(FlyBase, 2016)

1-64.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (3)

Bloomington

60039

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05032}attP40

VDRC

v102591

P{KK112091}VIE-260B

v12935

w¹¹¹⁸; P{GD4857}v12935

Genomic Clones (9)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (74)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

LD43683

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0031097

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0031097

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

33022

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Petkau et al., 2012)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: obst-A CG17052

(Behr and Hoch, 2005)

Source for database merge of

Additional comments

Other Comments

obst-A protects chitin from chitinase-dependent degradation.

(Petkau et al., 2012)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 29 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33022

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information