FB2021_02, released April 13, 2021

Gene: Dmel\obst-A

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General Information
Symbol
Dmel\obst-A
Species
D. melanogaster
Name
obstructor-A
Annotation Symbol
CG17052
Feature Type
protein_coding_gene
FlyBase ID
FBgn0031097
Gene Model Status
Current
Stock Availability
3 publicly available
Gene Summary
obstructor-A (obst-A) encodes a protein that forms a core complex with chitin and the chitin modifying proteins encoded by serp and knk. This complex is required for assembly, maturation and preservation of the chitinous cuticles at the end of embryogenesis and probably throughout larval development. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Key Links
Genomic Location
Cytogenetic map
19C1-19C1
Sequence location
X:20,239,855..20,243,209 [+]
Recombination map
1-64
RefSeq locus
NC_004354 REGION:20239855..20243209
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (8 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables chitin binding
inferred from direct assay
(Petkau et al., 2012)
enables structural constituent of chitin-based cuticle
inferred from direct assay
(Pesch et al., 2015, Petkau et al., 2012)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
involved_in chitin-based cuticle development
inferred from mutant phenotype
(Tiklová et al., 2013, Petkau et al., 2012)
involved_in larval chitin-based cuticle development
inferred from mutant phenotype
(Pesch et al., 2015)
involved_in negative regulation of extracellular matrix disassembly
inferred from mutant phenotype
(Petkau et al., 2012)
involved_in regulation of tube size, open tracheal system
inferred from mutant phenotype
(Tiklová et al., 2013)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in chitin-based extracellular matrix
inferred from direct assay
(Pesch et al., 2015, Tiklová et al., 2013, Petkau et al., 2012)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in extracellular region
inferred from electronic annotation with InterPro:IPR002557
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
obstructor-A (obst-A) encodes a protein that forms a core complex with chitin and the chitin modifying proteins encoded by serp and knk. This complex is required for assembly, maturation and preservation of the chitinous cuticles at the end of embryogenesis and probably throughout larval development. [Date last reviewed: 2019-03-14]
Gene Group (FlyBase)
OBSTRUCTOR FAMILY -
The Obstructor family encode secreted proteins with three chitin binding domains. Members of this family are involved in cuticle organisation. (Adapted from FBrf0190484 and FBrf0234504.)
CHITIN BINDING DOMAIN-CONTAINING PROTEINS -
Chitin binding domains are found in certain classes of chitin binding proteins and chitin-active enzymes. (Adapted from FBrf0108362.)
Summary (Interactive Fly)

secreted scaffold-like protein - binds chitin - recruits proteins for chitin-matrix growth - modulates localization of proteins at the ECM - controls tracheal tube diameter - affects cuticle stiffness during wound repair - promotes morphogenesis and axonal growth in the prothoracic gland

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\obst-A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.50

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
obst-A-RA
FBtr0077334
NM_134534
1905
237
obst-A-RB
FBtr0306737
NM_001258849
1235
237
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
obst-A-PA
FBpp0077026
26.6
237
4.38
NP_608378
AAF50927
obst-A-PB
FBpp0297663
26.6
237
4.38
NP_001245778
AFH07490
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

237 aa isoforms: obst-A-PA, obst-A-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\obst-A using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 11 -- 12
anterior spiracle primordium

Comment: reported as anterior spiracle specific anlage

(Fisher et al., 2012)
dorsal trunk primordium

Comment: reported as dorsal trunk specific anlage

(Fisher et al., 2012)
posterior spiracle primordium

Comment: reported as posterior spiracle specific anlage

(Fisher et al., 2012)
primary segmental branch primordium

Comment: reported as primary segmental branch specific anlage

(Fisher et al., 2012)
tracheal primordium
(Fisher et al., 2012)
visceral branch primordium

Comment: reported as visceral branch specific anlage

(Fisher et al., 2012)
embryonic stage 12 -- 16
embryonic/larval trachea
(Chung et al., 2011)
embryonic stage 13 -- 16
embryonic dorsal epidermis
(Fisher et al., 2012)
embryonic epipharynx
(Fisher et al., 2012)
embryonic head epidermis
(Fisher et al., 2012)
embryonic hypopharynx
(Fisher et al., 2012)
embryonic/larval dorsal branch
(Fisher et al., 2012)
embryonic/larval dorsal trunk
(Fisher et al., 2012)
embryonic/larval posterior spiracle
(Fisher et al., 2012)
embryonic/larval visceral branch
(Fisher et al., 2012)
embryonic stage 13 -- 17
embryonic/larval trachea
(Tiklová et al., 2013)
embryonic stage 14 -- 17
embryonic/larval tracheal system
(Petkau et al., 2012)
embryonic/larval hindgut
(Petkau et al., 2012)
embryonic/larval foregut
(Petkau et al., 2012)
embryonic/larval proventriculus
(Petkau et al., 2012)
embryonic/larval posterior spiracle
(Petkau et al., 2012)
embryonic stage 16 -- 17
embryonic/larval epidermis
(Petkau et al., 2012)
Additional Descriptive Data

obst-A expression is observed from embryonic stage 14 on in the tracheal system, foregut (including proventriculus and posterior spiracles), and in the hindgut. Epidermal expression starts at embryonic stage 16.

(Petkau et al., 2012)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 14 -- 17
embryonic/larval tracheal system
(Petkau et al., 2012)
embryonic/larval hindgut
(Petkau et al., 2012)
embryonic/larval foregut
(Petkau et al., 2012)
embryonic/larval proventriculus
(Petkau et al., 2012)
embryonic/larval posterior spiracle
(Petkau et al., 2012)
embryonic stage 16 -- 17
embryonic/larval epidermis
(Petkau et al., 2012)
Additional Descriptive Data

obst-A expression is observed from embryonic stage 14 on in the tracheal system, foregut (including proventriculus and posterior spiracles), and in the hindgut. Epidermal expression starts at embryonic stage 16.

(Petkau et al., 2012)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in chitin-based extracellular matrix
inferred from direct assay
(Pesch et al., 2015, Tiklová et al., 2013, Petkau et al., 2012)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\obst-A in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 5 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of obst-A
Transgenic constructs containing regulatory region of obst-A
Aberrations (Deficiencies and Duplications) ( 1 )
Inferred from experimentation ( 1 )
Gene disrupted in
Df(1)HM44
(Petkau et al., 2012)
Inferred from location ( 0 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (0)
No records found.
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (0)
No records found.
Rattus norvegicus (Norway rat) (0)
No records found.
Xenopus tropicalis (Western clawed frog) (0)
No records found.
Danio rerio (Zebrafish) (0)
No records found.
Caenorhabditis elegans (Nematode, roundworm) (6)
Cele\cpg-2
3 of 15
Yes
No
Cele\R02F2.4
3 of 15
Yes
No
Cele\cpg-1
2 of 15
No
Yes
Cele\C39D10.7
1 of 15
No
No
Cele\cbd-1
1 of 15
No
No
Cele\ule-1
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190D9U )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Dsim\GD28301
Drosophila sechellia
Dsec\GM23014
Drosophila erecta
Dere\GG19275
Drosophila yakuba
Dyak\GE17864
Drosophila ananassae
Dana\GF20239
Drosophila pseudoobscura pseudoobscura
Dpse\GA14300
Drosophila persimilis
Dper\GL13082
Drosophila willistoni
Dwil\GK25193
Drosophila virilis
Dvir\GJ15813
Drosophila mojavensis
Dmoj\GI11032
Drosophila grimshawi
Dgri\GH12617
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915071V )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17011588
Musca domestica
House fly
Mdoa\17018673
Glossina morsitans
Tsetse fly
Gmor\GMOY009572
Glossina morsitans
Tsetse fly
Gmor\GMOY004893
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_10455
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14048
Mayetiola destructor
Hessian fly
Mdes\Mdes014737
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013222
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012245
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL009577
Anopheles darlingi
American malaria mosquito
Adar\ADAC003739
Anopheles darlingi
American malaria mosquito
Adar\ADAC003744
Anopheles gambiae
Malaria mosquito
Agam\CPAP3-B
Anopheles gambiae
Malaria mosquito
Agam\CPAP3-A1c
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000680
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000679
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ006133
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0DQ1 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA007899
Bombyx mori
Silkmoth
Bmor\Bmo.1741
Bombyx mori
Silkmoth
Bmor\BGIBMGA007678
Bombyx mori
Silkmoth
Bmor\BGIBMGA007901
Danaus plexippus
Monarch butterfly
Dple\DPOGS213061-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213142-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213141-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213140-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL010346
Heliconius melpomene
Postman butterfly
Hmel\HMEL010347
Heliconius melpomene
Postman butterfly
Hmel\HMEL010348
Heliconius melpomene
Postman butterfly
Hmel\HMEL010349
Apis florea
Little honeybee
Aflo\2341655300
Apis florea
Little honeybee
Aflo\5578430180
Apis florea
Little honeybee
Aflo\2159461636
Apis florea
Little honeybee
Aflo\2341655108
Apis mellifera
Western honey bee
Amel\Cpap3-d
Apis mellifera
Western honey bee
Amel\Cpap3-b
Apis mellifera
Western honey bee
Amel\GB41945
Apis mellifera
Western honey bee
Amel\GB50636
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24007
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP23982
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24006
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP23981
Bombus terrestris
Buff-tailed bumblebee
Bter\15215281
Bombus terrestris
Buff-tailed bumblebee
Bter\15215280
Bombus terrestris
Buff-tailed bumblebee
Bter\15215229
Bombus terrestris
Buff-tailed bumblebee
Bter\15215228
Linepithema humile
Argentine ant
Lhum\LH18883
Linepithema humile
Argentine ant
Lhum\LH18878
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:000b80
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001fbc
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG036941
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG000845
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG000848
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG000844
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04719
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04720
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04722
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11656
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04721
Tribolium castaneum
Red flour beetle
Tcas\CPAP3-D1
Tribolium castaneum
Red flour beetle
Tcas\Obst-B
Tribolium castaneum
Red flour beetle
Tcas\CPAP3-A1
Tribolium castaneum
Red flour beetle
Tcas\CPAP3-A2
Pediculus humanus
Human body louse
Phum\PHUM434570
Pediculus humanus
Human body louse
Phum\PHUM434540
Pediculus humanus
Human body louse
Phum\PHUM434550
Rhodnius prolixus
Kissing bug
Rpro\RPRC010253
Rhodnius prolixus
Kissing bug
Rpro\RPRC010254
Rhodnius prolixus
Kissing bug
Rpro\RPRC010255
Cimex lectularius
Bed bug
Clec\CLEC008702
Cimex lectularius
Bed bug
Clec\CLEC007794
Cimex lectularius
Bed bug
Clec\CLEC008703
Cimex lectularius
Bed bug
Clec\CLEC025275
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI007911
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004093
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006031
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009786
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05889
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05888
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05892
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05890
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0DO1 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR007307
Ixodes scapularis
Black-legged tick
Isca\ISCW024120
Ixodes scapularis
Black-legged tick
Isca\ISCW013029
Ixodes scapularis
Black-legged tick
Isca\ISCW011513
Stegodyphus mimosarum
African social velvet spider
Smim\KFM69986.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM71245.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM66346.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79683.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur06g01550
Tetranychus urticae
Two-spotted spider mite
Turt\tetur27g00090
Tetranychus urticae
Two-spotted spider mite
Turt\tetur19g00240
Tetranychus urticae
Two-spotted spider mite
Turt\tetur15g01480
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_303616
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_93732
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_333110
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_230004
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0LTG )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Hypp_271
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Hypp_1196
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_024915gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_018580gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_021957gn
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000016289
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000005255
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000023680
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000016282
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (43)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Gasp
3 of 10
obst-B
3 of 10
CG4835
2 of 10
CG5883
2 of 10
CG5897
2 of 10
CG6933
2 of 10
CG6996
2 of 10
CG7017
2 of 10
CG7248
2 of 10
CG7252
2 of 10
CG7290
2 of 10
CG7298
2 of 10
CG10140
2 of 10
CG10154
2 of 10
CG10725
2 of 10
CG13806
2 of 10
CG17145
2 of 10
CG17147
2 of 10
CG17826
2 of 10
CG31077
2 of 10
CG32302
2 of 10
CG43896
2 of 10
obst-E
2 of 10
obst-F
2 of 10
obst-G
2 of 10
obst-J
2 of 10
Peritrophin-A
2 of 10
CG13312
1 of 10
CG13837
1 of 10
CG33263
1 of 10
CG33985
1 of 10
CG33986
1 of 10
CG34324
1 of 10
CG42397
1 of 10
CG42728
1 of 10
CG43218
1 of 10
CG43673
1 of 10
Muc68D
1 of 10
Muc68E
1 of 10
Mur2B
1 of 10
Mur89F
1 of 10
obst-H
1 of 10
obst-I
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser
    View in Interactions Browser
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    obst-A - knk
    pull down, western blot
    (Petkau et al., 2012)
    obst-A - serp
    pull down, western blot
    (Petkau et al., 2012)
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement
    View in Interactions Browser
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    obst-A
    enhanceable
    Gasp
    (Tiklová et al., 2013)
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Gasp
    enhanceable
    obst-A
    (Tiklová et al., 2013)
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map
    1-64
    Cytogenetic map
    19C1-19C1
    Sequence location
    X:20,239,855..20,243,209 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    19C1-19C1
    Limits computationally determined from genome sequence between P{EP}amnEP1639&P{EP}amnEP367 and P{EP}CG1702EP1525
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    1-64

    (FlyBase, 2016)

    1-64.0

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (3)
    Genomic Clones (9)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (74)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
       

      polyclonal

      (Petkau et al., 2012)
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of

      Source for identity of: obst-A CG17052

      (Behr and Hoch, 2005)
      Source for database merge of
      Additional comments
      Other Comments

      obst-A protects chitin from chitinase-dependent degradation.

      (Petkau et al., 2012)
      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 30 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
      InterPro - A database of protein families, domains and functional sites
      KEGG Genes - Molecular building blocks of life in the genomic space.
      modMine - A data warehouse for the modENCODE project
      Linkouts
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
      FlyMine - An integrated database for Drosophila genomics
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Synonyms and Secondary IDs (8)
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (47)