ObstA
secreted scaffold-like protein - binds chitin - recruits proteins for chitin-matrix growth - modulates localization of proteins at the ECM - controls tracheal tube diameter - affects cuticle stiffness during wound repair - promotes morphogenesis and axonal growth in the prothoracic gland
Please see the JBrowse view of Dmel\obst-A for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\obst-A using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: reported as anterior spiracle specific anlage
Comment: reported as dorsal trunk specific anlage
Comment: reported as posterior spiracle specific anlage
Comment: reported as primary segmental branch specific anlage
Comment: reported as visceral branch specific anlage
obst-A expression is observed from embryonic stage 14 on in the tracheal system, foregut (including proventriculus and posterior spiracles), and in the hindgut. Epidermal expression starts at embryonic stage 16.
obst-A expression is observed from embryonic stage 14 on in the tracheal system, foregut (including proventriculus and posterior spiracles), and in the hindgut. Epidermal expression starts at embryonic stage 16.
JBrowse - Visual display of RNA-Seq signals
View Dmel\obst-A in JBrowse1-64
1-64.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
obst-A protects chitin from chitinase-dependent degradation.
Source for identity of: obst-A CG17052