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Gene Dmel\CG14613

General Information
Symbol	Dmel\CG14613	Species	D. melanogaster
Name		Annotation symbol	CG14613
Feature type	protein_coding_gene	FlyBase ID	FBgn0031188
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	20C1-20C1	Sequence location	X:21,871,817..21,873,857 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG14613 (FBgn0031188). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF1279. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult salivary gland, larval trachea, adult ovary, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1638185_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG14613. Gene sequence location is X:21871817..21873857.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 20C1-20C1
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG14613 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG14613-RA FBtr0077367  NM_134619   1539   241 CG14613-RB FBtr0335047  NM_001272843   1755   241
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG14613-PA   FBpp0077059   26.6   241   9.82     NP_608463   AAF50951 CG14613-PB   FBpp0307051   26.6   241   9.82     NP_001259772   AGB95610
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1279 (IPR009688)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201261   AA802662   AA942534   AA952103   AE014298 AAF50951   AE014298 AGB95610   AI946611   AY060388 AAL25427   BF494071   BF506121   BF506170   BF506232   BG636695   BG637435   BG637510   BI167783   BI241517   BI241798   BI564047   BI566638   BI567930   BI570884   BI572725   BI589418   BI590925   BI591639   BI621182   CK658160   CO177811   CO267955   CO269753   CO287425   CO290746   CO313175   CO323945   CZ482295   EC070406   EC079893   EC086218   EC088044   EC208490   EC212919   EC231818   FD585996   FD586579   FD587267   FD587330   FD587371   FD587398   FD587542   GH739054   GH739860   GH739905   GH741560   GH744030   GH761644   GH768954
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VR55
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult salivary gland, larval trachea, adult ovary, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    97.775 Larval Midgut    79.1 Larval Hindgut    93.3 Larval Malpighian Tubules    57.2 Larval Fat Body    75.3 Larval Salivary Gland    86.9 Larval Trachea    137.8 Larval Carcass    83.35 Adult Head    54.8 Adult Eye    46.05 Adult Brain    82.2 Adult Thoracic-Abdominal Ganglion    68.7 Adult Crop    89.1 Adult Midgut    68.4 Adult Hindgut    89.4 Adult Malpighian Tubules    75.4 Adult Fat Body    55 Adult Salivary Gland    126.9 Adult Heart    63.075 Adult VirginFemale Spermatheca    38.3 Adult InseminatedFemale Spermatheca    42.8 Adult Ovary    234.5 Adult Testis    227.6 Adult Male Accessory Gland    131.2 Adult Carcass    67.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    54.8   NA  Eye    46.05   NA  Brain    82.2   97.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    68.7   NA  Crop    89.1   79.1  Midgut    68.4   93.3  Hindgut    89.4   57.2  Malpighian Tubules    75.4   75.3  Fat Body    55   86.9  Salivary Gland    126.9   NA  Heart    63.075   137.8  Trachea    NA   NA  VirginFemale Spermatheca    38.3   NA  InseminatedFemale Spermatheca    42.8   NA  Ovary    234.5   NA  Testis    227.6   NA  Male Accessory Gland    131.2   83.35  Carcass    67.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (48) central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female  (47) ovary, mated 4-day female  (60) testis, mated 4-day male  (57) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (48) central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female  (47) ovary, mated 4-day female  (60) testis, mated 4-day male  (57) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    48 central nervous system, larvae L3    13 central nervous system, pupae P8    12 head, virgin 1-day female    9 head, virgin 4-day female    11 head, virgin 20-day female    8 head, mated 1-day female    13 head, mated 4-day female    9 head, mated 20-day female    8 head, mated 1-day male    11 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    11 digestive system, 4-day adult    16 digestive system, 20-day adult    14 fat body, larvae L3 wandering    6 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    11 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    14 ovary, virgin 4-day female    47 ovary, mated 4-day female    60 testis, mated 4-day male    57 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (46) embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day  (27) adult male 30day    24 adult female 01day    24 adult female 05day  (33) adult female 30day  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (46) embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day  27 adult male 30day    24 adult female 01day    24 adult female 05day  (33) adult female 30day  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    9 embryo 04-06hr    3 embryo 06-08hr    4 embryo 08-10hr    5 embryo 10-12hr    10 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    12 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    9 larva L1    19 larva L2    19 larva L3 12hr old    15 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    18 pupae 2d postWPP    25 pupae 3d postWPP    20 pupae 4d postWPP    19 adult male 01day    20 adult male 05day    27 adult male 30day    24 adult female 01day    24 adult female 05day    33 adult female 30day    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (28) Schneider line 2 Sg4    24 embryonic 1182-4H  (48) embryonic GM2  (31) embryonic Kc167  (44) embryonic S1  (46) embryonic S3    24 leg disc CME L1  (31) wing disc CME-W2    24 wing disc ML-DmD8  (30) wing disc ML-DmD9  (55) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21  (36) wing disc ML-DmD32  (35) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11  (44) antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1  (41) CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS  (43) ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  28 Schneider line 2 Sg4    24 embryonic 1182-4H  (48) embryonic GM2  31 embryonic Kc167  (44) embryonic S1  (46) embryonic S3    24 leg disc CME L1  31 wing disc CME-W2    24 wing disc ML-DmD8  30 wing disc ML-DmD9  (55) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21  (36) wing disc ML-DmD32  (35) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11  (44) antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1  (41) CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS  (43) ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    28 Schneider line 2 Sg4    24 embryonic 1182-4H    48 embryonic GM2    31 embryonic Kc167    44 embryonic S1    46 embryonic S3    24 leg disc CME L1    31 wing disc CME-W2    24 wing disc ML-DmD8    30 wing disc ML-DmD9    55 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    36 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    44 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    18 ovary fGS/OSS    43 ovary OSC    23 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult  (28) Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult  (27) Cadmium 100 mM 48 hrs, 4-day adult  (39) Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3  (44) Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (37) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult  28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult  27 Cadmium 100 mM 48 hrs, 4-day adult  (39) Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3  (44) Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (37) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    28 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    27 Cadmium 100 mM 48 hrs, 4-day adult    39 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    23 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    44 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    37 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_26 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • LD29159 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031188 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14613-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG14613 Class Mutagen Stocks Known lesion CG14613e04543 piggyBac transposase 1 -- CG14613G224 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG14613 Class Mutagen Stocks Known lesion CG14613GD3714 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6255 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3714} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG14613e04543 NA insertion of mobile activating element P{EP}CG14613G224 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG14613 - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG14613 - Hsp26 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG14613 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031188 DroID - A comprehensive database of gene and protein interactions. • FBgn0031188
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6WH965 Dipteran inclusive ortholog search EOG6NVZVD Insect inclusive ortholog search EOG666TH2 Arthropod inclusive ortholog search EOG6P5HS8 Metazoa inclusive ortholog search EOG6B09J4
Orthologs in Drosophila Species (EOG6WH965)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG14613     Drosophila simulans   Dsim\GD15486 Y   Drosophila sechellia   Dsec\GM11723 Y   Drosophila erecta   Dere\GG17514 Y   Drosophila yakuba   Dyak\GE15270 Y   Drosophila ananassae   Dana\GF21272 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA22887 Y   Drosophila persimilis   Dper\GL25441     Drosophila persimilis   Dper\GL13428 Y   Drosophila willistoni   Dwil\GK16185 Y   Drosophila virilis   Dvir\GJ19007 Y   Drosophila mojavensis   Dmoj\GI15148 Y   Drosophila grimshawi   Dgri\GH17805 Y
Orthologs in non-Drosophila Dipterans (EOG6NVZVD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011684   Anopheles gambiae Malaria mosquito  Agam\AGAP003463   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005790
Orthologs in non-Dipteran Insects (EOG666TH2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40124   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001361   Atta cephalotes Leafcutter ant  Acep\ACEP24744   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14445   Linepithema humile Argentine ant  Lhum\LH22093   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14077   Acyrthosiphon pisum Pea aphid  Apim\ACYPI52223   Pediculus humanus Human body louse  Phum\PHUM394580   Tribolium castaneum Red flour beetle  Tcas\TC013920
Orthologs in non-Insect Arthropods (EOG6P5HS8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\hsdR   Ixodes scapularis Deer tick  Isca\ISCW023826
Orthologs in non-Arthropod Metazoa (EOG6B09J4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y56A3A.22   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014480gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014479gn   Danio rerio Zebrafish  Drer\ENSDARG00000040186   Danio rerio Zebrafish  Drer\ENSDARG00000035985   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000014708   Gallus gallus Domestic chicken  Ggal\FAM210A   Mus musculus House mouse  Mmus\ENSMUSG00000038121   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000016740   Homo sapiens Human  Hsap\FAM210A
Human Orthologs (1)
Gene OMIM HGNC Hsap\FAM210A
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15486 Drosophila sechellia Dsec\GM11723 Drosophila erecta Dere\GG17514 Drosophila yakuba Dyak\GE15270 Drosophila ananassae Dana\GF21272 Drosophila pseudoobscura pseudoobscura Dpse\GA22887 Drosophila persimilis Dper\GL13428 Drosophila willistoni Dwil\GK16185 Drosophila virilis Dvir\GJ19007 Drosophila mojavensis Dmoj\GI15148 Drosophila grimshawi Dgri\GH17805
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	33445 w* P{EP}CG14613G224
Harvard	- PBac{RB}CG14613e04543
Genomic Clones ( 1 )
	BACR06L03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 54 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD29159
Other clones	DPiM_LD29159
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02482 AT08513 AT08570 AT08657 GM06071 LD04206 LD26805 LP14788 RE08247 RE38607 RE38967 RH04618 RH05670 RH06396 RH08345 RH33853 RH35724 RH36340 RH39243 RH52486 SD14461 SD15439 SD15547
Other clones	65468 78572 106254 bs28f12 CK01.7A.E9 CK01.96D.D12 CK01.118A.F6 CK01.129B.C11 EK054346 EK065823 EK075048 EK089742 EK095810 EK192020 EK231815 RM03503 RM03603 RM03703 RM03803 RM03903 RM04003 RM04103 RP001005271 RP001007241 RP001010074 RP001029983 RP001047166 RP001051833 RP001054285
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031188 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33133
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134619 NM_001272843 RefSeq (Proteins) • NP_608463 NP_001259772 DDBJ / EMBL / GenBank • AA952103 AAF50951 AAL25427 AGB95610 AI946611 AY060388 CZ482295 Entrez Gene - A searchable database of RefSeq genes. • 33133 UniProtKB/TrEMBL • Q9VR55
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1279 (IPR009688) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD29159
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031188 DroID - A comprehensive database of gene and protein interactions. • FBgn0031188 DRSC - Results from RNAi screens. • FBgn0031188 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031188 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14613-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031188 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33133 modMine - Data generated by the modENCODE project. • FBgn0031188
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	ADP/ATP translocase (Zou et al., 2000) CG14613 (Cammarato et al., 2011) CT34370 (Ceriani et al., 2002)
Name Synonym
Secondary FlyBase IDs
References ( 16 )
Research paper	Ceriani et al., 2002, J. Neurosci. 22(21): 9305--9319 Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior. [FBrf0152147] Zou et al., 2000, Proc. Natl. Acad. Sci. U.S.A. 97(25): 13726--13731 Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. [FBrf0131436]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Bellen, 2010.12.8, BDGP_2010_1209.GenExel.xml BDGP_2010_1209.GenExel.xml [FBrf0212439] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] Oliver, 2001.8.16, Genome Res.: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]