General Information Symbol Dmel\ CG11455Species D. melanogaster Name Annotation symbol CG11455 Feature type protein_coding_gene FlyBase ID FBgn0031228 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 21B3-21B3 Sequence location 2L:114,726..156,030 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG11455 (FBgn0031228). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : NADH dehydrogenase activity. Based on sequence similarity, it is predicted to be involved in the
biological process : mitochondrial electron transport, NADH to ubiquinone.
3 alleles are reported . The
phenotype of these alleles is annotated with: trichogen cell. It has
11 annotated transcripts and
11 annotated polypeptides .
Protein features are: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634783_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CG11455. Gene sequence location is
2L:114726..156030 .
User Contributed Data
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It currently only tracks new links between this FlyBase report and other
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.48
Gene model reviewed during 5.44
Gene model reviewed during 5.51
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
- A database of annotated Dmel nuclear genes encoding mitochondrial proteins
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
1348.6
Larval Hindgut
1492.2
Larval Malpighian Tubules
1122.8
Larval Fat Body
778.8
Larval Salivary Gland
1104.6
Larval Trachea
745.4
Larval Carcass
1333.675
Adult Head
1161.3
Adult Eye
1580.05
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
1217
Adult Crop
1000.1
Adult Midgut
1221.8
Adult Hindgut
1358.5
Adult Malpighian Tubules
1139.9
Adult Fat Body
1477.5
Adult Salivary Gland
1669.6
Adult Heart
1154.425
Adult VirginFemale Spermatheca
2032.8
Adult InseminatedFemale Spermatheca
1669.5
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
1575.6
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(745.325)
Larval Midgut
(1348.6)
Larval Hindgut
(1492.2)
Larval Malpighian Tubules
(1122.8)
Larval Fat Body
(778.8)
Larval Salivary Gland
(1104.6)
Larval Trachea
(745.4)
Larval Carcass
(1333.675)
Adult Head
(1161.3)
Adult Eye
(1580.05)
Adult Brain
(933)
Adult Thoracic-Abdominal Ganglion
(1217)
Adult Crop
(1000.1)
Adult Midgut
(1221.8)
Adult Hindgut
(1358.5)
Adult Malpighian Tubules
(1139.9)
Adult Fat Body
(1477.5)
Adult Salivary Gland
(1669.6)
Adult Heart
(1154.425)
Adult VirginFemale Spermatheca
(2032.8)
Adult InseminatedFemale Spermatheca
(1669.5)
Adult Ovary
(572.6)
Adult Testis
(631.4)
Adult Male Accessory Gland
(804.3)
Adult Carcass
(1575.6)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
(1348.6)
Larval Hindgut
(1492.2)
Larval Malpighian Tubules
(1122.8)
Larval Fat Body
778.8
Larval Salivary Gland
(1104.6)
Larval Trachea
745.4
Larval Carcass
(1333.675)
Adult Head
(1161.3)
Adult Eye
(1580.05)
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
(1217)
Adult Crop
1000.1
Adult Midgut
(1221.8)
Adult Hindgut
(1358.5)
Adult Malpighian Tubules
(1139.9)
Adult Fat Body
(1477.5)
Adult Salivary Gland
(1669.6)
Adult Heart
(1154.425)
Adult VirginFemale Spermatheca
(2032.8)
Adult InseminatedFemale Spermatheca
(1669.5)
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
(1575.6)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
1348.6
Larval Hindgut
1492.2
Larval Malpighian Tubules
1122.8
Larval Fat Body
778.8
Larval Salivary Gland
1104.6
Larval Trachea
745.4
Larval Carcass
1333.675
Adult Head
1161.3
Adult Eye
1580.05
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
1217
Adult Crop
1000.1
Adult Midgut
1221.8
Adult Hindgut
1358.5
Adult Malpighian Tubules
1139.9
Adult Fat Body
1477.5
Adult Salivary Gland
1669.6
Adult Heart
1154.425
Adult VirginFemale Spermatheca
2032.8
Adult InseminatedFemale Spermatheca
1669.5
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
1575.6
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
1348.6
Larval Hindgut
1492.2
Larval Malpighian Tubules
1122.8
Larval Fat Body
778.8
Larval Salivary Gland
1104.6
Larval Trachea
745.4
Larval Carcass
1333.675
Adult Head
1161.3
Adult Eye
1580.05
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
1217
Adult Crop
1000.1
Adult Midgut
1221.8
Adult Hindgut
1358.5
Adult Malpighian Tubules
1139.9
Adult Fat Body
1477.5
Adult Salivary Gland
1669.6
Adult Heart
1154.425
Adult VirginFemale Spermatheca
2032.8
Adult InseminatedFemale Spermatheca
1669.5
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
1575.6
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
(1348.6)
Larval Hindgut
(1492.2)
Larval Malpighian Tubules
(1122.8)
Larval Fat Body
778.8
Larval Salivary Gland
(1104.6)
Larval Trachea
745.4
Larval Carcass
(1333.675)
Adult Head
(1161.3)
Adult Eye
(1580.05)
Adult Brain
(933)
Adult Thoracic-Abdominal Ganglion
(1217)
Adult Crop
(1000.1)
Adult Midgut
(1221.8)
Adult Hindgut
(1358.5)
Adult Malpighian Tubules
(1139.9)
Adult Fat Body
(1477.5)
Adult Salivary Gland
(1669.6)
Adult Heart
(1154.425)
Adult VirginFemale Spermatheca
(2032.8)
Adult InseminatedFemale Spermatheca
(1669.5)
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
(1575.6)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
1348.6
Larval Hindgut
1492.2
Larval Malpighian Tubules
1122.8
Larval Fat Body
778.8
Larval Salivary Gland
1104.6
Larval Trachea
745.4
Larval Carcass
1333.675
Adult Head
1161.3
Adult Eye
1580.05
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
1217
Adult Crop
1000.1
Adult Midgut
1221.8
Adult Hindgut
1358.5
Adult Malpighian Tubules
1139.9
Adult Fat Body
1477.5
Adult Salivary Gland
1669.6
Adult Heart
1154.425
Adult VirginFemale Spermatheca
(2032.8)
Adult InseminatedFemale Spermatheca
1669.5
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
1575.6
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
745.325
Larval Midgut
1348.6
Larval Hindgut
1492.2
Larval Malpighian Tubules
1122.8
Larval Fat Body
778.8
Larval Salivary Gland
1104.6
Larval Trachea
745.4
Larval Carcass
1333.675
Adult Head
1161.3
Adult Eye
1580.05
Adult Brain
933
Adult Thoracic-Abdominal Ganglion
1217
Adult Crop
1000.1
Adult Midgut
1221.8
Adult Hindgut
1358.5
Adult Malpighian Tubules
1139.9
Adult Fat Body
1477.5
Adult Salivary Gland
1669.6
Adult Heart
1154.425
Adult VirginFemale Spermatheca
2032.8
Adult InseminatedFemale Spermatheca
1669.5
Adult Ovary
572.6
Adult Testis
631.4
Adult Male Accessory Gland
804.3
Adult Carcass
1575.6
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
1161.3
NA
Eye
1580.05
NA
Brain
933
745.325
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
1217
NA
Crop
1000.1
1348.6
Midgut
1221.8
1492.2
Hindgut
1358.5
1122.8
Malpighian Tubules
1139.9
778.8
Fat Body
1477.5
1104.6
Salivary Gland
1669.6
NA
Heart
1154.425
745.4
Trachea
NA
NA
VirginFemale Spermatheca
2032.8
NA
InseminatedFemale Spermatheca
1669.5
NA
Ovary
572.6
NA
Testis
631.4
NA
Male Accessory Gland
804.3
1333.675
Carcass
1575.6
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
(29)
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
(29)
head, mated 4-day male
25
head, mated 20-day male
(30)
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
(32)
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
(41)
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
(69)
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
(41)
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
(69)
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
13
central nervous system, pupae P8
16
head, virgin 1-day female
29
head, virgin 4-day female
14
head, virgin 20-day female
12
head, mated 1-day female
16
head, mated 4-day female
16
head, mated 20-day female
10
head, mated 1-day male
29
head, mated 4-day male
25
head, mated 20-day male
30
salivary gland, larvae L3 wandering
11
salivary gland, white prepupae
8
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
32
digestive system, 4-day adult
19
digestive system, 20-day adult
16
fat body, larvae L3 wandering
4
fat body, white prepupae
8
fat body, pupae P8
17
carcass, larvae L3 wandering
14
carcass, 1-day adult
41
carcass, 4-day adult
19
carcass, 20-day adult
13
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
69
accessory gland, mated 4-day male
17
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
108
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
131
embryo 22-24hr
159
larva L1
143
larva L2
152
larva L3 12hr old
131
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
199
pupae 4d postWPP
169
adult male 01day
180
adult male 05day
121
adult male 30day
67
adult female 01day
120
adult female 05day
83
adult female 30day
65
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(54)
embryo 02-04hr
(63)
embryo 04-06hr
(99)
embryo 06-08hr
(71)
embryo 08-10hr
(76)
embryo 10-12hr
(108)
embryo 12-14hr
(76)
embryo 14-16hr
(73)
embryo 16-18hr
(91)
embryo 18-20hr
(98)
embryo 20-22hr
(131)
embryo 22-24hr
(159)
larva L1
(143)
larva L2
(152)
larva L3 12hr old
(131)
larva L3 puffstage 1-2
(88)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(68)
white prepupae new
(58)
white prepupae 12hr
(70)
white prepupae 24hr
(68)
pupae 2d postWPP
(105)
pupae 3d postWPP
(199)
pupae 4d postWPP
(169)
adult male 01day
(180)
adult male 05day
(121)
adult male 30day
(67)
adult female 01day
(120)
adult female 05day
(83)
adult female 30day
(65)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
(108)
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
(131)
embryo 22-24hr
(159)
larva L1
(143)
larva L2
(152)
larva L3 12hr old
(131)
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
(199)
pupae 4d postWPP
(169)
adult male 01day
(180)
adult male 05day
(121)
adult male 30day
67
adult female 01day
(120)
adult female 05day
83
adult female 30day
65
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
108
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
131
embryo 22-24hr
159
larva L1
143
larva L2
152
larva L3 12hr old
131
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
199
pupae 4d postWPP
169
adult male 01day
180
adult male 05day
121
adult male 30day
67
adult female 01day
120
adult female 05day
83
adult female 30day
65
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
108
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
131
embryo 22-24hr
159
larva L1
143
larva L2
152
larva L3 12hr old
131
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
199
pupae 4d postWPP
169
adult male 01day
180
adult male 05day
121
adult male 30day
67
adult female 01day
120
adult female 05day
83
adult female 30day
65
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(54)
embryo 02-04hr
(63)
embryo 04-06hr
(99)
embryo 06-08hr
(71)
embryo 08-10hr
(76)
embryo 10-12hr
(108)
embryo 12-14hr
(76)
embryo 14-16hr
(73)
embryo 16-18hr
(91)
embryo 18-20hr
(98)
embryo 20-22hr
(131)
embryo 22-24hr
(159)
larva L1
(143)
larva L2
(152)
larva L3 12hr old
(131)
larva L3 puffstage 1-2
(88)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(68)
white prepupae new
(58)
white prepupae 12hr
(70)
white prepupae 24hr
(68)
pupae 2d postWPP
(105)
pupae 3d postWPP
(199)
pupae 4d postWPP
(169)
adult male 01day
(180)
adult male 05day
(121)
adult male 30day
(67)
adult female 01day
(120)
adult female 05day
(83)
adult female 30day
(65)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
108
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
131
embryo 22-24hr
(159)
larva L1
143
larva L2
(152)
larva L3 12hr old
131
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
(199)
pupae 4d postWPP
(169)
adult male 01day
(180)
adult male 05day
121
adult male 30day
67
adult female 01day
120
adult female 05day
83
adult female 30day
65
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
54
embryo 02-04hr
63
embryo 04-06hr
99
embryo 06-08hr
71
embryo 08-10hr
76
embryo 10-12hr
108
embryo 12-14hr
76
embryo 14-16hr
73
embryo 16-18hr
91
embryo 18-20hr
98
embryo 20-22hr
131
embryo 22-24hr
159
larva L1
143
larva L2
152
larva L3 12hr old
131
larva L3 puffstage 1-2
88
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
68
white prepupae new
58
white prepupae 12hr
70
white prepupae 24hr
68
pupae 2d postWPP
105
pupae 3d postWPP
199
pupae 4d postWPP
169
adult male 01day
180
adult male 05day
121
adult male 30day
67
adult female 01day
120
adult female 05day
83
adult female 30day
65
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(37)
Schneider line 2 Sg4
(31)
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
(29)
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
(32)
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
(30)
wing disc ML-DmD21
(58)
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
(49)
eye-antennal disc ML-DmD11
(43)
antennal disc ML-DmD20-c5
(51)
mixed discs ML-DmD4-c1
(31)
CNS ML-DmBG1-c1
(66)
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(37)
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
(58)
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
(49)
eye-antennal disc ML-DmD11
(43)
antennal disc ML-DmD20-c5
(51)
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
(66)
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
37
Schneider line 2 Sg4
31
embryonic 1182-4H
20
embryonic GM2
26
embryonic Kc167
12
embryonic S1
29
embryonic S3
19
leg disc CME L1
17
wing disc CME-W2
26
wing disc ML-DmD8
32
wing disc ML-DmD9
22
wing disc ML-DmD16-c3
30
wing disc ML-DmD21
58
wing disc ML-DmD32
24
haltere disc ML-DmD17-c3
49
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
51
mixed discs ML-DmD4-c1
31
CNS ML-DmBG1-c1
66
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
20
ovary fGS/OSS
9
ovary OSC
15
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
(31)
Cadmium 50 mM 6 hrs, larvae L3
(36)
Cadmium 50 mM 12 hrs, larvae L3
(29)
Cadmium 50 mM 48 hrs, 4-day adult
(32)
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
(51)
Ethanol 10% 3 hrs, larvae L3
(36)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(30)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
(27)
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
(44)
Rotenone 8 μg 12 hrs, larvae L3
(43)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
(36)
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
(51)
Ethanol 10% 3 hrs, larvae L3
(36)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
(44)
Rotenone 8 μg 12 hrs, larvae L3
(43)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
12
cold shock, 4-day adult
8
heat shock, 4-day adult
31
Cadmium 50 mM 6 hrs, larvae L3
36
Cadmium 50 mM 12 hrs, larvae L3
29
Cadmium 50 mM 48 hrs, 4-day adult
32
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
20
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
23
Zinc 4.5 mM 48 hrs, 4-day adult
15
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
51
Ethanol 10% 3 hrs, larvae L3
36
Caffeine 1.5 mg/ml 4 hrs, larvae L3
30
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
13
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
27
Paraquat 10 mM 48 hrs, 4-day adult
25
Rotenone 2 μg 12 hrs, larvae L3
44
Rotenone 8 μg 12 hrs, larvae L3
43
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 1 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function Biological Process Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (32)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG6HX5MT )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG63N7P8 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG634V3X )
Apis mellifera
Western honey bee
Amel\GB45629
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG037326
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH11283
Atta cephalotes
Leafcutter ant
Acep\ACEP14266
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO20105
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL20978
Linepithema humile
Argentine ant
Lhum\LH17623
Pogonomyrmex barbatus
Red harvester ant
Pbar\CG:02550164
Solenopsis invicta
Red fire ant
Sinv\SINV26002
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6D256P )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington Harvard Kyoto VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 311 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- A database of annotated Dmel nuclear genes encoding mitochondrial proteins
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 3 )Reported As Symbol Synonym CG11455
(
Vilain et al., 2012 ,
Porcelli et al., 2007 ,
Tripoli et al., 2005 ,
Keleman et al., 2009.8.5 ,
Salzer et al., 2010 ,
Pessa et al., 2010 )
Name Synonym NADH:ubiquinone oxidoreductase 15 kDa subunit
NADH ubiquinone oxidoreductase 15 kDa
Secondary FlyBase
IDs References ( 23 )Generate a list of List References by type
Recent research papers ( 1 )
Vilain et al., 2012, PLoS Genet. 8(1): e1002456The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants. [FBrf0217195]