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Gene Dmel\CG4164

General Information
Symbol	Dmel\CG4164	Species	D. melanogaster
Name		Annotation symbol	CG4164
Feature type	protein_coding_gene	FlyBase ID	FBgn0031256
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	21C2-21C2	Sequence location	2L:453,108..454,654 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG4164 (FBgn0031256). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: unfolded protein binding. Based on sequence similarity, it is predicted to be involved in the biological process: response to heat. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Chaperone DnaJ, C-terminal; DnaJ domain; DnaJ domain, conserved site; HSP40/DnaJ peptide-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult heart, larval/adult salivary gland, virgin spermatheca, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637650_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG4164. Gene sequence location is 2L:453108..454654.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 21C2-21C2   Limits computationally determined from genome sequence between P{lacW}l(2)k09610k09610&P{lacW}Sk09538a and P{PZ}l(2)1068510685&P{lacW}Tango14k00619
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG4164 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG4164-RA FBtr0078060  NM_134681   1488   354
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG4164-PA   FBpp0077720   40.2   354   5.36     NP_608525   AAF51493
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • DnaJ domain (IPR001623) Chaperone DnaJ, C-terminal (IPR002939) HSP40/DnaJ peptide-binding (IPR008971) DnaJ domain, conserved site (IPR018253)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140798   AA140799   AA391008   AA950501   AE014134 AAF51493   AI107782   AI135262   AI293705   AI404758   AI514306   AW943021   AY051778 AAK93202   BF489058   BI214508   BI230759   BI485849   BI577551   BI632664   BI633192   BP553224   BP553225   CO287457   CO307882   CO308755   CO309642   CO314136   CO320704   CZ466502   EC064516   EC088255   EC090092   EC090523   EC203778   EC226510   EC243793   EL872493   ES690242   ES690260   ES690261   ES690278   ES690279   ES690282   ES690288   ES690303   ES695967   EV590297   GH753274   GH757605   GH758187   GH779088   GH792790   GH805432   GH808450   GH812289   GH814408   GH840462   GH842083   GH847480   GH848326   GH849297   GH853026   GH853774   GH860117   GH862462   GH872307   GH874827   GH875664   GH879409   GH892225   GH898830   GH903915   GH907887   GH911581   GH914210   GH914348   GH915235   GH916027   GH916593   GH916907   GH920665   GH930542   GH935407
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VPQ2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   garland cell primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) plasmatocyte primordium   (Fisher et al., 2012) Comment:reported as plasmatocytes anlage embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval salivary gland   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) plasmatocyte   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult heart, larval/adult salivary gland, virgin spermatheca, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland    1323.3 Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland    1160.3 Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland  (1323.3) Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland  (587.1) Adult Heart  (547.725) Adult VirginFemale Spermatheca  522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland  (1160.3) Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland  (1323.3) Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland  (1160.3) Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland    1323.3 Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland    1160.3 Adult Carcass    287.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland    1323.3 Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland    1160.3 Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland  (1323.3) Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland  587.1 Adult Heart  547.725 Adult VirginFemale Spermatheca  522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland  (1160.3) Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland  1323.3 Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland  1160.3 Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    300.175 Larval Midgut    326.2 Larval Hindgut    245.7 Larval Malpighian Tubules    439.7 Larval Fat Body    296.2 Larval Salivary Gland    1323.3 Larval Trachea    299.975 Larval Carcass    299.275 Adult Head    249.5 Adult Eye    239.825 Adult Brain    166.4 Adult Thoracic-Abdominal Ganglion    171.1 Adult Crop    247.8 Adult Midgut    346.2 Adult Hindgut    142 Adult Malpighian Tubules    213.5 Adult Fat Body    476.3 Adult Salivary Gland    587.1 Adult Heart    547.725 Adult VirginFemale Spermatheca    522.5 Adult InseminatedFemale Spermatheca    490.2 Adult Ovary    376.6 Adult Testis    175.3 Adult Male Accessory Gland    1160.3 Adult Carcass    287.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    249.5   NA  Eye    239.825   NA  Brain    166.4   300.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    171.1   NA  Crop    247.8   326.2  Midgut    346.2   245.7  Hindgut    142   439.7  Malpighian Tubules    213.5   296.2  Fat Body    476.3   1323.3  Salivary Gland    587.1   NA  Heart    547.725   299.975  Trachea    NA   NA  VirginFemale Spermatheca    522.5   NA  InseminatedFemale Spermatheca    490.2   NA  Ovary    376.6   NA  Testis    175.3   NA  Male Accessory Gland    1160.3   299.275  Carcass    287.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male    109 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (56) central nervous system, larvae L3  (46) central nervous system, pupae P8  (35) head, virgin 1-day female  (35) head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male  26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae  (80) digestive system, larvae L3 wandering  (32) digestive system, 1-day adult  (39) digestive system, 4-day adult  (33) digestive system, 20-day adult  (27) fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8  (60) carcass, larvae L3 wandering  (46) carcass, 1-day adult    24 carcass, 4-day adult  (29) carcass, 20-day adult  (29) ovary, virgin 4-day female  (64) ovary, mated 4-day female  (51) testis, mated 4-day male  (62) accessory gland, mated 4-day male  (109) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male  (109) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male    109 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male    109 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (56) central nervous system, larvae L3  (46) central nervous system, pupae P8  (35) head, virgin 1-day female  (35) head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male  26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae  (80) digestive system, larvae L3 wandering  32 digestive system, 1-day adult  (39) digestive system, 4-day adult  (33) digestive system, 20-day adult  27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8  (60) carcass, larvae L3 wandering  (46) carcass, 1-day adult    24 carcass, 4-day adult  29 carcass, 20-day adult  29 ovary, virgin 4-day female  (64) ovary, mated 4-day female  (51) testis, mated 4-day male  (62) accessory gland, mated 4-day male  (109) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male  109 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    56 central nervous system, larvae L3    46 central nervous system, pupae P8    35 head, virgin 1-day female    35 head, virgin 4-day female    23 head, virgin 20-day female    22 head, mated 1-day female    20 head, mated 4-day female    18 head, mated 20-day female    24 head, mated 1-day male    18 head, mated 4-day male    24 head, mated 20-day male    26 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    80 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    39 digestive system, 4-day adult    33 digestive system, 20-day adult    27 fat body, larvae L3 wandering    24 fat body, white prepupae    22 fat body, pupae P8    60 carcass, larvae L3 wandering    46 carcass, 1-day adult    24 carcass, 4-day adult    29 carcass, 20-day adult    29 ovary, virgin 4-day female    64 ovary, mated 4-day female    51 testis, mated 4-day male    62 accessory gland, mated 4-day male    109 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (90) embryo 04-06hr  (69) embryo 06-08hr  (79) embryo 08-10hr  (78) embryo 10-12hr  (82) embryo 12-14hr  (62) embryo 14-16hr  (44) embryo 16-18hr  (37) embryo 18-20hr  (27) embryo 20-22hr    21 embryo 22-24hr    18 larva L1  (32) larva L2  (65) larva L3 12hr old  (41) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  (31) larva L3 puffstage 7-9  (35) white prepupae new  (46) white prepupae 12hr  26 white prepupae 24hr  (37) pupae 2d postWPP  (33) pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day  (28) adult male 05day  (30) adult male 30day  26 adult female 01day  26 adult female 05day  (42) adult female 30day  (46) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (90) embryo 04-06hr  (69) embryo 06-08hr  (79) embryo 08-10hr  (78) embryo 10-12hr  (82) embryo 12-14hr  (62) embryo 14-16hr  (44) embryo 16-18hr  (37) embryo 18-20hr  27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1  32 larva L2  (65) larva L3 12hr old  (41) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  31 larva L3 puffstage 7-9  (35) white prepupae new  (46) white prepupae 12hr  26 white prepupae 24hr  (37) pupae 2d postWPP  (33) pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day  28 adult male 05day  30 adult male 30day  26 adult female 01day  26 adult female 05day  (42) adult female 30day  (46) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    90 embryo 04-06hr    69 embryo 06-08hr    79 embryo 08-10hr    78 embryo 10-12hr    82 embryo 12-14hr    62 embryo 14-16hr    44 embryo 16-18hr    37 embryo 18-20hr    27 embryo 20-22hr    21 embryo 22-24hr    18 larva L1    32 larva L2    65 larva L3 12hr old    41 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    35 white prepupae new    46 white prepupae 12hr    26 white prepupae 24hr    37 pupae 2d postWPP    33 pupae 3d postWPP    17 pupae 4d postWPP    13 adult male 01day    28 adult male 05day    30 adult male 30day    26 adult female 01day    26 adult female 05day    42 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    147 Schneider line 2 Sg4    102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3    209 leg disc CME L1    105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1    117 CNS ML-DmBG2-c2    101 tumorous blood cells mbn2    278 ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (147) Schneider line 2 Sg4  (102) embryonic 1182-4H  (71) embryonic GM2  (94) embryonic Kc167  (88) embryonic S1  (70) embryonic S3  (209) leg disc CME L1  (105) wing disc CME-W2  (42) wing disc ML-DmD8  (44) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3  (61) wing disc ML-DmD21  (45) wing disc ML-DmD32  (66) haltere disc ML-DmD17-c3  (81) eye-antennal disc ML-DmD11  (67) antennal disc ML-DmD20-c5  (98) mixed discs ML-DmD4-c1  (94) CNS ML-DmBG1-c1  (117) CNS ML-DmBG2-c2  (101) tumorous blood cells mbn2  (278) ovary fGS/OSS    21 ovary OSC  (35) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (147) Schneider line 2 Sg4  102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3  (209) leg disc CME L1  105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1  (117) CNS ML-DmBG2-c2  101 tumorous blood cells mbn2  (278) ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    147 Schneider line 2 Sg4    102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3    209 leg disc CME L1    105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1    117 CNS ML-DmBG2-c2    101 tumorous blood cells mbn2    278 ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    147 Schneider line 2 Sg4    102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3    209 leg disc CME L1    105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1    117 CNS ML-DmBG2-c2    101 tumorous blood cells mbn2    278 ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (147) Schneider line 2 Sg4  (102) embryonic 1182-4H  (71) embryonic GM2  (94) embryonic Kc167  (88) embryonic S1  (70) embryonic S3  (209) leg disc CME L1  (105) wing disc CME-W2  (42) wing disc ML-DmD8  (44) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3  (61) wing disc ML-DmD21  (45) wing disc ML-DmD32  (66) haltere disc ML-DmD17-c3  (81) eye-antennal disc ML-DmD11  (67) antennal disc ML-DmD20-c5  (98) mixed discs ML-DmD4-c1  (94) CNS ML-DmBG1-c1  (117) CNS ML-DmBG2-c2  (101) tumorous blood cells mbn2  (278) ovary fGS/OSS    21 ovary OSC  (35) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (147) Schneider line 2 Sg4  102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3  (209) leg disc CME L1  105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1  117 CNS ML-DmBG2-c2  101 tumorous blood cells mbn2  (278) ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    147 Schneider line 2 Sg4    102 embryonic 1182-4H    71 embryonic GM2    94 embryonic Kc167    88 embryonic S1    70 embryonic S3    209 leg disc CME L1    105 wing disc CME-W2    42 wing disc ML-DmD8    44 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    61 wing disc ML-DmD21    45 wing disc ML-DmD32    66 haltere disc ML-DmD17-c3    81 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    98 mixed discs ML-DmD4-c1    94 CNS ML-DmBG1-c1    117 CNS ML-DmBG2-c2    101 tumorous blood cells mbn2    278 ovary fGS/OSS    21 ovary OSC    35 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult  (51) Cadmium 50 mM 6 hrs, larvae L3  (62) Cadmium 50 mM 12 hrs, larvae L3  (58) Cadmium 50 mM 48 hrs, 4-day adult  (52) Cadmium 100 mM 48 hrs, 4-day adult  (53) Copper 0.5 mM 12 hrs, larvae L3  (36) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  (50) Ethanol 5% 3 hrs, larvae L3  (57) Ethanol 10% 3 hrs, larvae L3  (66) Caffeine 1.5 mg/ml 4 hrs, larvae L3  26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (42) Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult  (44) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3  (74) Rotenone 8 μg 12 hrs, larvae L3  (69) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult  (51) Cadmium 50 mM 6 hrs, larvae L3  (62) Cadmium 50 mM 12 hrs, larvae L3  (58) Cadmium 50 mM 48 hrs, 4-day adult  (52) Cadmium 100 mM 48 hrs, 4-day adult  (53) Copper 0.5 mM 12 hrs, larvae L3  (36) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  (50) Ethanol 5% 3 hrs, larvae L3  (57) Ethanol 10% 3 hrs, larvae L3  (66) Caffeine 1.5 mg/ml 4 hrs, larvae L3  26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (42) Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult  (44) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3  (74) Rotenone 8 μg 12 hrs, larvae L3  (69) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    24 cold shock, 4-day adult    16 heat shock, 4-day adult    51 Cadmium 50 mM 6 hrs, larvae L3    62 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    36 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    50 Ethanol 5% 3 hrs, larvae L3    57 Ethanol 10% 3 hrs, larvae L3    66 Caffeine 1.5 mg/ml 4 hrs, larvae L3    26 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    42 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    74 Rotenone 8 μg 12 hrs, larvae L3    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • LD30318 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031256 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4164-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG4164 Stages(s) 1-3 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | recessive CG416402 viable, with Scer\GAL4pnr-MD237 CG4164GD12785 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG4164 Class Mutagen Stocks Known lesion CG416402 1 Yes CG4164c00496 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG4164 Class Mutagen Stocks Known lesion CG4164GD12785 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG4164HMS01649 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4164KK101364 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4164NIG.4164R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12785} NA P{KK101364} NA P{NIG.4164R} NA P{TRiP.HMS01649} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{UASp-YFP.Rab23}CG416402 NA PBac{PB}CG4164c00496 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
unfolded protein binding inferred from electronic annotation with InterPro:IPR002939, InterPro:IPR003095, InterPro:IPR008971 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
protein folding inferred from electronic annotation with InterPro:IPR002939, InterPro:IPR003095, InterPro:IPR008971 (FlyBase Curators et al., 2004-) response to heat inferred from sequence or structural similarity with EMBL:AF088983 (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG4164 - Aats-lys anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Arf79F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - B52 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - BEAF-32 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG11563 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG14695 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG16753 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG1832 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG32344 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG43444 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG4553 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG4806 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG6701 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG6937 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG7006 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG7903 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG8478 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CG8545 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Cdc5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Cg25C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Fmr1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Hel25E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Mat89Ba anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Mec2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Mtr3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - NHP2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Ns1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Nup50 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Ostγ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Pgam5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - RpL24-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - RpL35A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - RpL7-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - RpS12 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - RpS27A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Rpt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Rrp46 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Rs1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - SF1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Ski6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Srp72 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - Tango4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - U2af38 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - U4-U6-60K anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - alt anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - ball anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - cathD anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - cue anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - dbe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - hyd anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - lola anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - mRpL44 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - mRpS30 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - mod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - mor anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - pic anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - ppan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - qkr58E-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - sbr anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4164 - snama anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG4164 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59476 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031256 DroID - A comprehensive database of gene and protein interactions. • FBgn0031256 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33220
Orthologs
OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6960BW Dipteran inclusive ortholog search EOG6HMJK2 Insect inclusive ortholog search EOG6BZKZ9 Arthropod inclusive ortholog search EOG631ZDQ Metazoa inclusive ortholog search EOG61VXWV
Orthologs in Drosophila Species (EOG6960BW)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG4164     Drosophila simulans   Dsim\GD23027 Y   Drosophila sechellia   Dsec\GM16745 Y   Drosophila erecta   Dere\GG24722 Y   Drosophila yakuba   Dyak\GE16847 Y   Drosophila ananassae   Dana\GF20662 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17999 Y   Drosophila persimilis   Dper\GL18879 Y   Drosophila willistoni   Dwil\GK24395 Y   Drosophila virilis   Dvir\GJ17778 Y   Drosophila mojavensis   Dmoj\GI21690 Y   Drosophila grimshawi   Dgri\GH11226 Y   Drosophila grimshawi   Dgri\GH11414
Orthologs in non-Drosophila Dipterans (EOG6HMJK2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009946   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013020   Anopheles gambiae Malaria mosquito  Agam\AGAP008327   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802431
Orthologs in non-Dipteran Insects (EOG6BZKZ9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC552223   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG019914   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19515   Atta cephalotes Leafcutter ant  Acep\ACEP26857   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20539   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23153   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23154   Linepithema humile Argentine ant  Lhum\LH24868   Pogonomyrmex barbatus Red harvester ant  Pbar\PB19131   Solenopsis invicta Red fire ant  Sinv\SINV25510   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001453   Bombyx mori Silkmoth  Bmor\BGIBMGA003153   Pediculus humanus Human body louse  Phum\PHUM145620   Tribolium castaneum Red flour beetle  Tcas\TC013491
Orthologs in non-Insect Arthropods (EOG631ZDQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_206336   Ixodes scapularis Deer tick  Isca\ISCW021534
Orthologs in non-Arthropod Metazoa (EOG61VXWV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\dnj-20   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021154gn   Danio rerio Zebrafish  Drer\dnajb11   Xenopus tropicalis Western clawed frog  Xtro\dnajb11   Gallus gallus Domestic chicken  Ggal\DNAJB11   Mus musculus House mouse  Mmus\Dnajb11   Rattus norvegicus Norway rat  Rnor\Dnajb11   Homo sapiens Human  Hsap\DNAJB11
Human Orthologs (1)
Gene OMIM HGNC Hsap\DNAJB11
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23027 Drosophila sechellia Dsec\GM16745 Drosophila erecta Dere\GG24722 Drosophila yakuba Dyak\GE16847 Drosophila ananassae Dana\GF20662 Drosophila pseudoobscura pseudoobscura Dpse\GA17999 Drosophila persimilis Dper\GL18879 Drosophila willistoni Dwil\GK24395 Drosophila virilis Dvir\GJ17778 Drosophila mojavensis Dmoj\GI21690 Drosophila grimshawi Dgri\GH11226
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	37507 y1 sc* v1; P{TRiP.HMS01649}attP40 9803 y1 w*; P{UASp-YFP.Rab23}CG416402/CyO
Harvard	- PBac{PB}CG4164c00496
VDRC	v108576 P{KK101364}VIE-260B v22996 w1118; P{GD12785}v22996 v22997 w1118; P{GD12785}v22997
Genomic Clones ( 1 )
	BACR16A12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 61 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD30318
Other clones	DPiM_LD30318
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24757 GH05633 GH12934 GH24584 LD09904 LD36240 LP06904 RE14791 RE20337 RE69195 RE71248 SD26494 SD27207
Other clones	CK01016 Dmel_neb_010644_0339_3531 EK065913 EK218711 EK235159 EK255927 EK259249 EK287258 FGM223C08 IP04405 RP003001828 RP003010630 RP003034376 RP003044651 RP003067394 RP003073887 RP003123223 RP003133233 RP003134736 RP003150133 RP003161383 RP003162624 RP003185809 RP003219648 RP003221484 RP003232055 RP003245565 RP003254160 RP003255018 RP003256216 RP003275265 RP003283816 RP003294382 RP003301028 RP003334247 RP003337537 RP003400828 RP003468374 RP003514588 RP003532256 RP003537325 RP003552730 RP003598731 RP003644902 RP003661380 RP003667710
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031256 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33220
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134681 RefSeq (Proteins) • NP_608525 DDBJ / EMBL / GenBank • AA950501 AAF51493 AAK93202 AW943021 AY051778 CZ466502 Entrez Gene - A searchable database of RefSeq genes. • 33220 UniProtKB/TrEMBL • Q9VPQ2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • DnaJ domain (IPR001623) Chaperone DnaJ, C-terminal (IPR002939) HSP40/DnaJ peptide-binding (IPR008971) DnaJ domain, conserved site (IPR018253) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD30318
Linkouts
	BioGRID - A database of protein and genetic interactions • 59476 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031256 DroID - A comprehensive database of gene and protein interactions. • FBgn0031256 DRSC - Results from RNAi screens. • FBgn0031256 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031256 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4164-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031256 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33220 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33220 modMine - Data generated by the modENCODE project. • FBgn0031256
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG4164 (Hollien and Weissman, 2006, Zhang et al., 2007, Ni et al., 2011.7.19, Juhász et al., 2007, Keleman et al., 2009.8.5, Cammarato et al., 2011, Rehwinkel et al., 2004, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 3 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...