FB2019_05, released Oct 15, 2019

Gene: Dmel\Ipk2

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General Information
Symbol
Dmel\Ipk2
Species
D. melanogaster
Name
Ipk2
Annotation Symbol
CG13688
Feature Type
protein_coding_gene
FlyBase ID
FBgn0031267
Gene Model Status
Current
Stock Availability
5 publicly available
Enzyme Name (EC)
Inositol-trisphosphate 3-kinase (2.7.1.127)
Inositol-tetrakisphosphate 5-kinase (2.7.1.140)
Inositol-polyphosphate multikinase (2.7.1.151)
Gene Snapshot
Ipk2 (Ipk2) encodes a kinase involved in imaginal disc development and biosynthesis of inositol phosphate. [Date last reviewed: 2019-09-12]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
21E2-21E2
Sequence location
2L:573,033..574,264 [-]
Recombination map
2-1.5
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
inositol tetrakisphosphate 5-kinase activity; inositol-1,4,5-trisphosphate 3-kinase activity; inositol-1,4,5-trisphosphate 6-kinase activity
Predictions / Assertions
-
Catalytic Activity (EC)
Experimental Evidence
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate (2.7.1.127)
ATP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate (2.7.1.140)
2 ATP + 1D-myo-inositol 1,4,5-trisphosphate = 2 ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate (2.7.1.151)
Predictions / Assertions
-
Summaries
Gene Group (FlyBase)
INOSITOL PHOSPHATE KINASES -
Inositol phosphate kinases catalyze the phosphorylation of inositol phosphates. (Adapted from PMID:17954248)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\Ipk2 or the JBrowse view of Dmel\Ipk2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.42
Gene model reviewed during 5.45
Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Ipk2-RA
FBtr0078074
NM_134691
1232
309
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Ipk2-PA
FBpp0077734
35.3
309
8.06
NP_608535
AAF51477
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ipk2 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (6 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
inositol tetrakisphosphate 5-kinase activity
inferred from direct assay
(Seeds et al., 2004)
inositol-1,4,5-trisphosphate 3-kinase activity
inferred from direct assay
(Seeds et al., 2004)
inositol-1,4,5-trisphosphate 6-kinase activity
inferred from direct assay
(Seeds et al., 2004)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
imaginal disc development
inferred from mutant phenotype
(Seeds et al., 2015)
inositol phosphate biosynthetic process
inferred from direct assay
(Seeds et al., 2004)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
nucleoplasm
inferred from direct assay
(Seeds et al., 2004)
Terms Based on Predictions or Assertions (0 terms)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
epitope tag
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
salivary gland
(Seeds et al., 2004)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
nucleoplasm
inferred from direct assay
(Seeds et al., 2004)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Ipk2 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 3 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Ipk2
Transgenic constructs containing regulatory region of Ipk2
Deletions and Duplications ( 3 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal - all die before end of P-stage
lethal - all die before end of P-stage (with Ipk220B)
lethal - all die before end of P-stage (with Ipk240B)
lethal - all die before end of P-stage | germline clone
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
cell cycle defective | third instar larval stage
decreased occurrence of cell division | third instar larval stage
developmental rate defective
hypoplasia | P-stage
increased cell death | third instar larval stage
majority die during P-stage
majority die during P-stage (with Ipk220B)
majority die during P-stage (with Ipk240B)
short lived | heat sensitive, with Scer\GAL4tin.CΔ4
some die during larval stage
some die during larval stage (with Ipk220B)
some die during larval stage (with Ipk240B)
visible | P-stage
Phenotype manifest in
Allele
adult epidermis | P-stage | germline clone | maternal effect
adult head | P-stage | germline clone | maternal effect
adult thorax | P-stage | germline clone | maternal effect
imaginal disc | germline clone | maternal effect | third instar larval stage
interommatidial bristle | P-stage
leg | P-stage | germline clone | maternal effect
notopleural bristle | P-stage
ommatidium | P-stage
postnotum | P-stage
presutural bristle | P-stage
wing | P-stage
wing | P-stage | germline clone | maternal effect
wing disc | third instar larval stage
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\IPMK
10 of 15
Yes
Yes
Hsap\IP6K1
1 of 15
No
No
Hsap\IP6K2
1 of 15
No
No
Hsap\IP6K3
1 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Ipmk
10 of 15
Yes
Yes
Mmus\Ip6k1
1 of 15
No
No
Mmus\Ip6k2
1 of 15
No
No
Mmus\Ip6k3
1 of 15
No
No
Rattus norvegicus (Norway rat) (1)
Rnor\Ipmk
8 of 13
Yes
Yes
Xenopus tropicalis (Western clawed frog) (2)
Xtro\ipmk
5 of 12
Yes
Yes
Xtro\ip6k2
1 of 12
No
No
Danio rerio (Zebrafish) (5)
Drer\ipmkb
10 of 15
Yes
Yes
Drer\ipmka
6 of 15
No
Yes
Drer\ip6k1
1 of 15
No
No
Drer\ip6k2a
1 of 15
No
No
Drer\ip6k2b
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\ipmk-1
11 of 15
Yes
Yes
Cele\F30A10.3
1 of 15
No
No
Cele\Y22D7AR.6
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (2)
Atha\IPK2a
6 of 9
Yes
Yes
 
 
Atha\IPK2BETA
6 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\ARG82
4 of 15
Yes
Yes
 
 
Scer\KCS1
2 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPAC607.04
4 of 12
Yes
Yes
Spom\SPCC970.08
1 of 12
No
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190DON )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\Ipk2
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00000064
Drosophila simulans
Dsim\GD22857
Drosophila sechellia
Dsec\GM16655
Drosophila erecta
Dere\GG24638
Drosophila yakuba
Dyak\GE16007
Drosophila ananassae
Dana\GF14878
Drosophila pseudoobscura pseudoobscura
Dpse\GA12460
Drosophila persimilis
Dper\GL19251
Drosophila willistoni
Dwil\GK24631
Drosophila virilis
Dvir\GJ19687
Drosophila mojavensis
Dmoj\GI18022
Drosophila grimshawi
Dgri\GH10503
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508JA )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17012703
Glossina morsitans
Tsetse fly
Gmor\GMOY008617
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_11260
Anopheles darlingi
American malaria mosquito
Adar\ADAC005809
Anopheles gambiae
Malaria mosquito
Agam\AGAP012099
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ006477
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0A3D )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA007408
Bombyx mori
Silkmoth
Bmor\BGIBMGA007360
Bombyx mori
Silkmoth
Bmor\BGIBMGA007362
Bombyx mori
Silkmoth
Bmor\BGIBMGA007409
Danaus plexippus
Monarch butterfly
Dple\DPOGS213172-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213171-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213213-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL002989
Heliconius melpomene
Postman butterfly
Hmel\HMEL002990
Apis florea
Little honeybee
Aflo\2721118420
Apis mellifera
Western honey bee
Amel\Ipk2
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24247
Bombus terrestris
Buff-tailed bumblebee
Bter\15210278
Linepithema humile
Argentine ant
Lhum\LH17247
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002e0e
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG008227
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11999
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11998
Tribolium castaneum
Red flour beetle
Tcas\TC005770
Tribolium castaneum
Red flour beetle
Tcas\TC005769
Pediculus humanus
Human body louse
Phum\PHUM268940
Pediculus humanus
Human body louse
Phum\PHUM268930
Rhodnius prolixus
Kissing bug
Rpro\RPRC005394
Rhodnius prolixus
Kissing bug
Rpro\RPRC011764
Cimex lectularius
Bed bug
Clec\CLEC007643
Cimex lectularius
Bed bug
Clec\CLEC001450
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI010176
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI007085
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_00709
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_00705
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X094D )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR015020
Ixodes scapularis
Black-legged tick
Isca\ISCW017482
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70953.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur05g00360
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_223065
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0KJW )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Impk
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Impk_1
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000024683
Gallus gallus
Domestic chicken
Ggal\IPMK
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (3)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG10082
3 of 10
IP3K1
1 of 10
IP3K2
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    IPMK; inositol polyphosphate multikinase
    10 of 15
    609851
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Dmel gene
        Ortholog showing functional complementation
        Supporting References
        Ipk2
        Atha\IPK2a
        (Seeds et al., 2015)
        Ipk2
        Scer\ARG82
        (Seeds et al., 2015)
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Interactions Browser
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Ipk2
        suppressible
        Dronc
        (Seeds et al., 2015)
        Ipk2
        suppressible
        hop
        (Seeds et al., 2015)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        upd1
        suppressible
        Ipk2
        (Seeds et al., 2015)
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Gene Group - Pathway Membership (FlyBase)
        External Data
        Linkouts
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map
        2-1.5
        Cytogenetic map
        21E2-21E2
        Sequence location
        2L:573,033..574,264 [-]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        21E2-21E2
        Limits computationally determined from genome sequence between P{lacW}l(2)k09610k09610&P{lacW}Sk09538a and P{PZ}l(2)1068510685&P{lacW}Tango14k00619
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location
        2-1.5
        (FlyBase, 2016)
        2-0.2
        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (5)
        Genomic Clones (11)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (8)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequences
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of
        Source for identity of: Ipk2 CG13688
        (Seeds et al., 2004)
        Source for database merge of
        Additional comments
        FlyBase curator comment: the insertion in the "f05607" Exelixis line (PBac{WH}CG2813f05607) was originally assigned to the Ipk2 gene in FBrf0179797, resulting in the "Ipk2f05607" (FBal0160279) allele. However, FBrf0184340 shows that the insertion is actually within CG2813.
        (Bloomington Drosophila Stock Center, 2004.11.6)
        Other Comments
        The Ipk2 enzyme is a 6-/3-kinase that converts inositol 1,4,5-trisphosphate to inositol 1,3,4,5,6-pentakisphosphate and this is likely to be a processive reaction where the majority of the inositol 1,4,5,6-tetrakisphosphate intermediate is phosphorylated rather than released. In addition, the Ipk2 enzyme harbours 5-kinase activity towards inositol 1,3,4,6-tetrakisphosphate.
        (Seeds et al., 2004)
        Origin and Etymology
        Discoverer
        Etymology
        Identification
        External Crossreferences and Linkouts ( 36 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        modMine - A data warehouse for the modENCODE project
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyMine - An integrated database for Drosophila genomics
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Synonyms and Secondary IDs (4)
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (28)