• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG4764

General Information
Symbol	Dmel\CG4764	Species	D. melanogaster
Name		Annotation symbol	CG4764
Feature type	protein_coding_gene	FlyBase ID	FBgn0031310
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	VPS29
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	21F1-21F1	Sequence location	2L:1,150,766..1,151,764 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG4764 (FBgn0031310). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: hydrolase activity, acting on ester bonds. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Calcineurin-like phosphoesterase superfamily domain; Phosphodiesterase MJ0936. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1629155_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG4764. Gene sequence location is 2L:1150766..1151764.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 21F1-21F1   Limits computationally determined from genome sequence between P{PZ}l(2)1068510685&P{lacW}Tango14k00619 and P{lacW}RFeSPk11704
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG4764 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG4764-RA FBtr0077960  NM_134731   999   182
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG4764-PA   FBpp0077625   20.5   182   7.02     NP_608575   AAF51410
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphodiesterase MJ0936 (IPR000979) Calcineurin-like phosphoesterase superfamily domain (IPR024654)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF51410   AI063948   AI405762   AW941000   AX094011   AY060789 AAL28337   BH740789   BI230216   BI625488   BI626882   CL868488   CO189419   CZ487122   CZ488154   DQ138680 ABA86286   DQ440120   EC218155   EV580642   GH947263   GH961614
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VPX5 Q2XYI2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   garland cell primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval garland cell   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    248.35 Larval Midgut    161.4 Larval Hindgut    203.4 Larval Malpighian Tubules    281.4 Larval Fat Body    161.5 Larval Salivary Gland    236.8 Larval Trachea    152.625 Larval Carcass    136.25 Adult Head    141.1 Adult Eye    144.775 Adult Brain    174 Adult Thoracic-Abdominal Ganglion    155.2 Adult Crop    219.3 Adult Midgut    175.8 Adult Hindgut    178.1 Adult Malpighian Tubules    122.4 Adult Fat Body    110.1 Adult Salivary Gland    217.4 Adult Heart    265.35 Adult VirginFemale Spermatheca    82.1 Adult InseminatedFemale Spermatheca    77.6 Adult Ovary    242.3 Adult Testis    222.6 Adult Male Accessory Gland    282.5 Adult Carcass    135 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    141.1   NA  Eye    144.775   NA  Brain    174   248.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    155.2   NA  Crop    219.3   161.4  Midgut    175.8   203.4  Hindgut    178.1   281.4  Malpighian Tubules    122.4   161.5  Fat Body    110.1   236.8  Salivary Gland    217.4   NA  Heart    265.35   152.625  Trachea    NA   NA  VirginFemale Spermatheca    82.1   NA  InseminatedFemale Spermatheca    77.6   NA  Ovary    242.3   NA  Testis    222.6   NA  Male Accessory Gland    282.5   136.25  Carcass    135 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (40) central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female  (31) ovary, mated 4-day female  (27) testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (40) central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female  31 ovary, mated 4-day female  27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    21 central nervous system, pupae P8    14 head, virgin 1-day female    11 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    8 head, mated 4-day female    6 head, mated 20-day female    10 head, mated 1-day male    13 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    13 digestive system, 4-day adult    8 digestive system, 20-day adult    15 fat body, larvae L3 wandering    6 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    14 ovary, virgin 4-day female    31 ovary, mated 4-day female    27 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (67) embryo 02-04hr  (77) embryo 04-06hr  (49) embryo 06-08hr  (53) embryo 08-10hr  (56) embryo 10-12hr  (56) embryo 12-14hr  (36) embryo 14-16hr  (40) embryo 16-18hr  (27) embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1  (27) larva L2  (29) larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  (32) larva L3 puffstage 7-9  (36) white prepupae new  (42) white prepupae 12hr  (37) white prepupae 24hr  (47) pupae 2d postWPP  (38) pupae 3d postWPP  (29) pupae 4d postWPP    25 adult male 01day  (30) adult male 05day  (37) adult male 30day  (38) adult female 01day  (35) adult female 05day  (38) adult female 30day  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (67) embryo 02-04hr  (77) embryo 04-06hr  (49) embryo 06-08hr  (53) embryo 08-10hr  (56) embryo 10-12hr  (56) embryo 12-14hr  (36) embryo 14-16hr  (40) embryo 16-18hr  27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1  27 larva L2  29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  32 larva L3 puffstage 7-9  (36) white prepupae new  (42) white prepupae 12hr  (37) white prepupae 24hr  (47) pupae 2d postWPP  (38) pupae 3d postWPP  29 pupae 4d postWPP    25 adult male 01day  30 adult male 05day  (37) adult male 30day  (38) adult female 01day  (35) adult female 05day  (38) adult female 30day  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    67 embryo 02-04hr    77 embryo 04-06hr    49 embryo 06-08hr    53 embryo 08-10hr    56 embryo 10-12hr    56 embryo 12-14hr    36 embryo 14-16hr    40 embryo 16-18hr    27 embryo 18-20hr    22 embryo 20-22hr    18 embryo 22-24hr    17 larva L1    27 larva L2    29 larva L3 12hr old    24 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    36 white prepupae new    42 white prepupae 12hr    37 white prepupae 24hr    47 pupae 2d postWPP    38 pupae 3d postWPP    29 pupae 4d postWPP    25 adult male 01day    30 adult male 05day    37 adult male 30day    38 adult female 01day    35 adult female 05day    38 adult female 30day    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    161 Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (161) Schneider line 2 Sg4  (51) embryonic 1182-4H  (53) embryonic GM2  (44) embryonic Kc167  (56) embryonic S1  (73) embryonic S3  (41) leg disc CME L1  (57) wing disc CME-W2  (36) wing disc ML-DmD8  (40) wing disc ML-DmD9  (59) wing disc ML-DmD16-c3  (37) wing disc ML-DmD21  (64) wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3  (68) eye-antennal disc ML-DmD11  (67) antennal disc ML-DmD20-c5  (106) mixed discs ML-DmD4-c1  (43) CNS ML-DmBG1-c1  (54) CNS ML-DmBG2-c2  (35) tumorous blood cells mbn2  (61) ovary fGS/OSS  (30) ovary OSC  26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (161) Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5  106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    161 Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    161 Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (161) Schneider line 2 Sg4  (51) embryonic 1182-4H  (53) embryonic GM2  (44) embryonic Kc167  (56) embryonic S1  (73) embryonic S3  (41) leg disc CME L1  (57) wing disc CME-W2  (36) wing disc ML-DmD8  (40) wing disc ML-DmD9  (59) wing disc ML-DmD16-c3  (37) wing disc ML-DmD21  (64) wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3  (68) eye-antennal disc ML-DmD11  (67) antennal disc ML-DmD20-c5  (106) mixed discs ML-DmD4-c1  (43) CNS ML-DmBG1-c1  (54) CNS ML-DmBG2-c2  (35) tumorous blood cells mbn2  (61) ovary fGS/OSS  30 ovary OSC  26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (161) Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5  106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    161 Schneider line 2 Sg4    51 embryonic 1182-4H    53 embryonic GM2    44 embryonic Kc167    56 embryonic S1    73 embryonic S3    41 leg disc CME L1    57 wing disc CME-W2    36 wing disc ML-DmD8    40 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    64 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    68 eye-antennal disc ML-DmD11    67 antennal disc ML-DmD20-c5    106 mixed discs ML-DmD4-c1    43 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    61 ovary fGS/OSS    30 ovary OSC    26 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3  (29) Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3  29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • GH25884 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031310 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4764-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG4764 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG4764EY11288 viable, with Scer\GAL4pnr-MD237 CG4764GD11421 Sterility Allele fertile CG4764EY11288 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG4764 Class Mutagen Stocks Known lesion CG4764EY11288 P-element activity 1 -- CG4764f04578 piggyBac transposase 1 -- CG4764f05556 piggyBac transposase 1 -- CG4764KG02700 P-element activity 1 -- CG4764CB-6628-3 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG4764 Class Mutagen Stocks Known lesion CG4764GD11421 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4764HMS01877 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4764KK108809 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4764αTub84B.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes CG4764αTub84B.T:Disc\RFP-mCherry in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6004 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11421} NA P{KK108809} NA P{TRiP.HMS01877} NA characterization construct P{αTub84B-CG4764.EGFP} NA P{αTub84B-CG4764.mCherry} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG4764EY11288 NA miscellaneous insertions P{RS3}CG4764CB-6628-3 NA P{SUPor-P}CG4764KG02700 NA PBac{WH}CG4764f04578 NA PBac{WH}CG4764f05556 NA insertion of enhancer trap P{lacW}l(2)SH1895SH1895 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
hydrolase activity, acting on ester bonds inferred from electronic annotation with InterPro:IPR000979 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG4764 - ATPsyn-γ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - AnxB10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Arf79F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Art8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG12262 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG13385 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG13473 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG4764 - CG1416 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG2010 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG30008 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG4764 - CG4169 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG4278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG5961 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG6073 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG7039 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG4764 - CG7580 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG8258 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG8368 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG8678 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - CG9253 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Chc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Droj2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Gale anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Hel25E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - ImpL3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Jon44E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - MESK2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Nurf-38 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - P32 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Pk17E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Pp4-19C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Prosβ6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rab6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rab7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - RagC-D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Ras85D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - RpS12 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Rpt6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Sec13 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Sucb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Tcp-1ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Tcp-1η anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Vps26 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG4764 - Vps35 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - Vps4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - ade5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - bsh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - cathD anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - l(1)G0320 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - morgue anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - nemy anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - porin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - r anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - ref(2)P anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - rev7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - skpF anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - wal anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG4764 - εCOP anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG4764 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59548 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031310 DroID - A comprehensive database of gene and protein interactions. • FBgn0031310 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33295
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6SN285 Dipteran inclusive ortholog search EOG6MW8G8 Insect inclusive ortholog search EOG637QB7 Arthropod inclusive ortholog search EOG6QZ636 Metazoa inclusive ortholog search EOG6NSG68
Orthologs in Drosophila Species (EOG6SN285)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG4764     Drosophila simulans   Dsim\GD23074 Y   Drosophila sechellia   Dsec\GM16798 Y   Drosophila erecta   Dere\GG24770 Y   Drosophila yakuba   Dyak\GE17363 Y   Drosophila ananassae   Dana\GF15167 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18414 Y   Drosophila persimilis   Dper\GL15595 Y   Drosophila willistoni   Dwil\GK24671 Y   Drosophila virilis   Dvir\GJ19542 Y   Drosophila mojavensis   Dmoj\GI17980 Y   Drosophila grimshawi   Dgri\GH11176 Y
Orthologs in non-Drosophila Dipterans (EOG6MW8G8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001733   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011192   Anopheles gambiae Malaria mosquito  Agam\AGAP002338   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011219
Orthologs in non-Dipteran Insects (EOG637QB7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC725700   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005265   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20601   Atta cephalotes Leafcutter ant  Acep\ACEP12876   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14861   Linepithema humile Argentine ant  Lhum\LH10726   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25649   Acyrthosiphon pisum Pea aphid  Apim\ACYPI081823   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009312   Bombyx mori Silkmoth  Bmor\BGIBMGA013190   Pediculus humanus Human body louse  Phum\PHUM607960   Tribolium castaneum Red flour beetle  Tcas\GLEAN_15687
Orthologs in non-Insect Arthropods (EOG6QZ636)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_93995   Ixodes scapularis Deer tick  Isca\ISCW016107
Orthologs in non-Arthropod Metazoa (EOG6NSG68)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\vps-29   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023026gn   Danio rerio Zebrafish  Drer\vps29   Xenopus tropicalis Western clawed frog  Xtro\vps29   Gallus gallus Domestic chicken  Ggal\VPS29   Gallus gallus Domestic chicken  Ggal\LOC416931   Rattus norvegicus Norway rat  Rnor\Vps29   Homo sapiens Human  Hsap\VPS29
Human Orthologs (1)
Gene OMIM HGNC Hsap\VPS29
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23074 Drosophila sechellia Dsec\GM16798 Drosophila erecta Dere\GG24770 Drosophila yakuba Dyak\GE17363 Drosophila ananassae Dana\GF15167 Drosophila pseudoobscura pseudoobscura Dpse\GA18414 Drosophila persimilis Dper\GL15595 Drosophila willistoni Dwil\GK24671 Drosophila virilis Dvir\GJ19542 Drosophila mojavensis Dmoj\GI17980 Drosophila grimshawi Dgri\GH11176
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	20672 y1 w67c23; P{EPgy2}CG4764EY11288 38963 y1 sc* v1; P{TRiP.HMS01877}attP40 13491 y1 w67c23; P{SUPor-P}CG4764KG02700
Harvard	- PBac{WH}CG4764f04578 - PBac{WH}CG4764f05556
VDRC	v101375 P{KK108809}VIE-260B v26625 w1118; P{GD11421}v26625
Genomic Clones ( 1 )
	BACR38A03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH25884
Other clones	DPiM_GH25884
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04072 GM15249 RH65924 RH67975
Other clones	Dmel_dig_000932_0616_3691 EK044229 RP004211714 RP004534454
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031310 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33295
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Area matching Drosophila EST AI405762. This EST has sequence similarity to hypothetical proteins from Arabidopsis and C. elegans. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134731 RefSeq (Proteins) • NP_608575 DDBJ / EMBL / GenBank • AAF51410 AAL28337 ABA86286 AI405762 AW941000 AX094011 AY060789 BH740789 CL868488 CZ487122 CZ488154 DQ138680 Entrez Gene - A searchable database of RefSeq genes. • 33295 UniProtKB/TrEMBL • Q2XYI2 Q9VPX5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphodiesterase MJ0936 (IPR000979) Calcineurin-like phosphoesterase superfamily domain (IPR024654) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH25884
Linkouts
	BioGRID - A database of protein and genetic interactions • 59548 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031310 DroID - A comprehensive database of gene and protein interactions. • FBgn0031310 DRSC - Results from RNAi screens. • FBgn0031310 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031310 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4764-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031310 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33295 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33295 modMine - Data generated by the modENCODE project. • FBgn0031310
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG4764 (Keleman et al., 2009.8.5, Cammarato et al., 2011, Burgess et al., 2012, Ni et al., 2010.12.1) VPS29 (Wishart et al., 2012) Vps29 (Burgess et al., 2012)
Name Synonym
Secondary FlyBase IDs
References ( 26 )
Generate a list of	All references relating to this gene ( 26 )
List References by type	Research paper  ( 2 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 1 ) Patent  ( 1 ) DNA/RNA sequence record  ( 4 ) Website  ( 1 )
Recent research papers ( 2 )
	Burgess et al., 2012, Development 139(16): 3040--3050 Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila. [FBrf0219013] Wishart et al., 2012, PLoS Genet. 8(8): e1002936 Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. [FBrf0219374] Show all research papers ...