Gene Dmel\CG17660

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General Information

Symbol

Dmel\CG17660

Species

D. melanogaster

Name

Annotation symbol

CG17660

Feature type

protein_coding_gene

FlyBase ID

FBgn0031356

Gene Model Status

Current

Stock availability

2 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

22B1-22B1

Sequence location

2L:1,707,132..1,710,421 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG17660 (FBgn0031356). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Transmembrane receptor, eukaryota. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1629600_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG17660. Gene sequence location is 2L:1707132..1710421.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

22B1-22B1

Limits computationally determined from genome sequence between P{PZ}l(2)04111⁰⁴¹¹¹ and P{lacW}CG17646^k11021

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG17660 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.46

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG17660-RA

FBtr0077912

NM_134768

2357

536

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG17660-PA

FBpp0077578

60.1

536

5.84

NP_608612

AAF51348

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Transmembrane receptor, eukaryota (IPR009637)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VQ34

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		1178.3
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		(921)
Larval Hindgut		525.1
Larval Malpighian Tubules		(639.2)
Larval Fat Body		170.8
Larval Salivary Gland		(699.7)
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		(1033.5)
Adult Midgut		(679.7)
Adult Hindgut		520.9
Adult Malpighian Tubules		(770.1)
Adult Fat Body		178.5
Adult Salivary Gland		(1178.3)
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		(1178.3)
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		1178.3
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		1178.3
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		(921)
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		(1033.5)
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		(1178.3)
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		1178.3
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		319.8
Larval Midgut		921
Larval Hindgut		525.1
Larval Malpighian Tubules		639.2
Larval Fat Body		170.8
Larval Salivary Gland		699.7
Larval Trachea		189.4
Larval Carcass		240.275
Adult Head		146.2
Adult Eye		140.425
Adult Brain		237.4
Adult Thoracic-Abdominal Ganglion		235.9
Adult Crop		1033.5
Adult Midgut		679.7
Adult Hindgut		520.9
Adult Malpighian Tubules		770.1
Adult Fat Body		178.5
Adult Salivary Gland		1178.3
Adult Heart		138.45
Adult VirginFemale Spermatheca		140
Adult InseminatedFemale Spermatheca		149.6
Adult Ovary		295.5
Adult Testis		209.7
Adult Male Accessory Gland		380.4
Adult Carcass		150.9
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	146.2
NA	Eye	140.425
NA	Brain	237.4
319.8	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	235.9
NA	Crop	1033.5
921	Midgut	679.7
525.1	Hindgut	520.9
639.2	Malpighian Tubules	770.1
170.8	Fat Body	178.5
699.7	Salivary Gland	1178.3
NA	Heart	138.45
189.4	Trachea	NA
NA	VirginFemale Spermatheca	140
NA	InseminatedFemale Spermatheca	149.6
NA	Ovary	295.5
NA	Testis	209.7
NA	Male Accessory Gland	380.4
240.275	Carcass	150.9

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(41)
central nervous system, larvae L3		(40)
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		(29)
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		(41)
digestive system, larvae L3 wandering		(63)
digestive system, 1-day adult		(32)
digestive system, 4-day adult		(30)
digestive system, 20-day adult		(48)
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		(29)
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		(56)
ovary, mated 4-day female		(51)
testis, mated 4-day male		(34)
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(41)
central nervous system, larvae L3		(40)
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		(41)
digestive system, larvae L3 wandering		(63)
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		(48)
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		(56)
ovary, mated 4-day female		(51)
testis, mated 4-day male		(34)
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		41
central nervous system, larvae L3		40
central nervous system, pupae P8		24
head, virgin 1-day female		17
head, virgin 4-day female		17
head, virgin 20-day female		19
head, mated 1-day female		16
head, mated 4-day female		15
head, mated 20-day female		14
head, mated 1-day male		25
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		63
digestive system, 1-day adult		32
digestive system, 4-day adult		30
digestive system, 20-day adult		48
fat body, larvae L3 wandering		11
fat body, white prepupae		23
fat body, pupae P8		15
carcass, larvae L3 wandering		29
carcass, 1-day adult		13
carcass, 4-day adult		17
carcass, 20-day adult		18
ovary, virgin 4-day female		56
ovary, mated 4-day female		51
testis, mated 4-day male		34
accessory gland, mated 4-day male		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(47)
embryo 02-04hr		17
embryo 04-06hr		(42)
embryo 06-08hr		(44)
embryo 08-10hr		(38)
embryo 10-12hr		(30)
embryo 12-14hr		(28)
embryo 14-16hr		(27)
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		(28)
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		(27)
larva L3 puffstage 3-6		(31)
larva L3 puffstage 7-9		(34)
white prepupae new		(36)
white prepupae 12hr		(31)
white prepupae 24hr		(34)
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		(32)
adult male 30day		(36)
adult female 01day		(32)
adult female 05day		(39)
adult female 30day		(40)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(47)
embryo 02-04hr		17
embryo 04-06hr		(42)
embryo 06-08hr		(44)
embryo 08-10hr		(38)
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		(34)
white prepupae new		(36)
white prepupae 12hr		31
white prepupae 24hr		(34)
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		(36)
adult female 01day		32
adult female 05day		(39)
adult female 30day		(40)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		47
embryo 02-04hr		17
embryo 04-06hr		42
embryo 06-08hr		44
embryo 08-10hr		38
embryo 10-12hr		30
embryo 12-14hr		28
embryo 14-16hr		27
embryo 16-18hr		22
embryo 18-20hr		19
embryo 20-22hr		18
embryo 22-24hr		19
larva L1		28
larva L2		24
larva L3 12hr old		23
larva L3 puffstage 1-2		27
larva L3 puffstage 3-6		31
larva L3 puffstage 7-9		34
white prepupae new		36
white prepupae 12hr		31
white prepupae 24hr		34
pupae 2d postWPP		23
pupae 3d postWPP		17
pupae 4d postWPP		18
adult male 01day		26
adult male 05day		32
adult male 30day		36
adult female 01day		32
adult female 05day		39
adult female 30day		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		116
embryonic Kc167		70
embryonic S1		156
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		140
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(74)
Schneider line 2 Sg4		(44)
embryonic 1182-4H		(75)
embryonic GM2		(116)
embryonic Kc167		(70)
embryonic S1		(156)
embryonic S3		(47)
leg disc CME L1		(53)
wing disc CME-W2		(71)
wing disc ML-DmD8		(49)
wing disc ML-DmD9		(63)
wing disc ML-DmD16-c3		(44)
wing disc ML-DmD21		(41)
wing disc ML-DmD32		(80)
haltere disc ML-DmD17-c3		(57)
eye-antennal disc ML-DmD11		(69)
antennal disc ML-DmD20-c5		(55)
mixed discs ML-DmD4-c1		(44)
CNS ML-DmBG1-c1		(51)
CNS ML-DmBG2-c2		(140)
tumorous blood cells mbn2		(78)
ovary fGS/OSS		(41)
ovary OSC		(28)
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		(116)
embryonic Kc167		70
embryonic S1		(156)
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		(140)
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		116
embryonic Kc167		70
embryonic S1		156
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		140
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		116
embryonic Kc167		70
embryonic S1		156
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		140
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(74)
Schneider line 2 Sg4		(44)
embryonic 1182-4H		(75)
embryonic GM2		(116)
embryonic Kc167		(70)
embryonic S1		(156)
embryonic S3		(47)
leg disc CME L1		(53)
wing disc CME-W2		(71)
wing disc ML-DmD8		(49)
wing disc ML-DmD9		(63)
wing disc ML-DmD16-c3		(44)
wing disc ML-DmD21		(41)
wing disc ML-DmD32		(80)
haltere disc ML-DmD17-c3		(57)
eye-antennal disc ML-DmD11		(69)
antennal disc ML-DmD20-c5		(55)
mixed discs ML-DmD4-c1		(44)
CNS ML-DmBG1-c1		(51)
CNS ML-DmBG2-c2		(140)
tumorous blood cells mbn2		(78)
ovary fGS/OSS		(41)
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		116
embryonic Kc167		70
embryonic S1		(156)
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		140
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		74
Schneider line 2 Sg4		44
embryonic 1182-4H		75
embryonic GM2		116
embryonic Kc167		70
embryonic S1		156
embryonic S3		47
leg disc CME L1		53
wing disc CME-W2		71
wing disc ML-DmD8		49
wing disc ML-DmD9		63
wing disc ML-DmD16-c3		44
wing disc ML-DmD21		41
wing disc ML-DmD32		80
haltere disc ML-DmD17-c3		57
eye-antennal disc ML-DmD11		69
antennal disc ML-DmD20-c5		55
mixed discs ML-DmD4-c1		44
CNS ML-DmBG1-c1		51
CNS ML-DmBG2-c2		140
tumorous blood cells mbn2		78
ovary fGS/OSS		41
ovary OSC		28
ovary OSS		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		(32)
Cadmium 100 mM 48 hrs, 4-day adult		(48)
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		(30)
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		(42)
Ethanol 5% 3 hrs, larvae L3		(34)
Ethanol 10% 3 hrs, larvae L3		(27)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(33)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(43)
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		(32)
Paraquat 10 mM 48 hrs, 4-day adult		(38)
Rotenone 2 μg 12 hrs, larvae L3		(30)
Rotenone 8 μg 12 hrs, larvae L3		(28)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		(48)
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		(42)
Ethanol 5% 3 hrs, larvae L3		(34)
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(33)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(43)
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		(38)
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		26
cold shock, 4-day adult		17
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		26
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		48
Copper 0.5 mM 12 hrs, larvae L3		17
Copper 15 mM 48 hrs, 4-day adult		30
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		25
Ethanol 2.5% 3 hrs, larvae L3		42
Ethanol 5% 3 hrs, larvae L3		34
Ethanol 10% 3 hrs, larvae L3		27
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		43
Caffeine 25 mg/ml 48 hrs, 4-day adult		21
Paraquat 5 mM 48 hrs, 4-day adult		32
Paraquat 10 mM 48 hrs, 4-day adult		38
Rotenone 2 μg 12 hrs, larvae L3		30
Rotenone 8 μg 12 hrs, larvae L3		28
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0031356

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17660-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG17660^GD387

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG17660	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG17660	Class	Mutagen	Stocks	Known lesion
CG17660^GD387		in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG17660^KK100631		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel6005

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD387}

P{KK100631}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function ( 0 terms)

Biological Process ( 0 terms)

Cellular Component

CV term

Evidence

References

integral to membrane

inferred from electronic annotation with InterPro:IPR009637

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG17660 - CG31523

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

CG17660 - Hip14

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG17660 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

59587

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0031356

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33347

Orthologs

OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6DNFQ3

Dipteran inclusive ortholog search

EOG6XWG63

Insect inclusive ortholog search

EOG6ZGN82

Arthropod inclusive ortholog search

EOG6SBCDN

Metazoa inclusive ortholog search

EOG6F81CS

Orthologs in Drosophila Species (EOG6DNFQ3)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14601

Drosophila persimilis

Dper\GL19345

Drosophila willistoni

Dwil\GK14938

Drosophila virilis

Dvir\GJ10662

Drosophila mojavensis

Dmoj\GI17078

Drosophila grimshawi

Dgri\GH10317

Orthologs in non-Drosophila Dipterans (EOG6XWG63)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL002694

Anopheles gambiae

Malaria mosquito

Agam\AGAP007934

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ015753

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004765

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004766

Orthologs in non-Dipteran Insects (EOG6ZGN82)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002497

Bombyx mori

Silkmoth

Bmor\BGIBMGA010435

Pediculus humanus

Human body louse

Phum\PHUM347370

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_07919

Orthologs in non-Insect Arthropods (EOG6SBCDN)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Tpx2

Ixodes scapularis

Deer tick

Isca\ISCW019030

Orthologs in non-Arthropod Metazoa (EOG6F81CS)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\C52B9.4

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_018185gn

Danio rerio

Zebrafish

Drer\ENSDARG00000079533

Danio rerio

Zebrafish

Drer\zgc:162698

Xenopus tropicalis

Western clawed frog

Xtro\tmem87a

Xenopus tropicalis

Western clawed frog

Xtro\tmem87b

Gallus gallus

Domestic chicken

Ggal\TMEM87A

Mus musculus

House mouse

Mmus\Tmem87b

Mus musculus

House mouse

Mmus\Tmem87a

Rattus norvegicus

Norway rat

Rnor\Tmem87a

Rattus norvegicus

Norway rat

Rnor\Tmem87b

Homo sapiens

Human

Hsap\TMEM87B

Homo sapiens

Human

Hsap\TMEM87A

Human Orthologs (2)

Gene

OMIM

HGNC

Hsap\TMEM87B

Hsap\TMEM87A

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14601

Drosophila persimilis

Dper\GL19345

Drosophila willistoni

Dwil\GK14938

Drosophila virilis

Dvir\GJ10662

Drosophila mojavensis

Dmoj\GI17078

Drosophila grimshawi

Dgri\GH10317

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

VDRC

v2685

w¹¹¹⁸; P{GD387}v2685

v2684

w¹¹¹⁸; P{GD387}v2684/TM3

Genomic Clones ( 1 )

BACR19B15

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 30 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

GH17801

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0031356

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33347

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_134768

RefSeq (Proteins)

•

NP_608612

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

33347

UniProtKB/TrEMBL

•

Q9VQ34

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Transmembrane receptor, eukaryota (IPR009637)

Linkouts

BioGRID - A database of protein and genetic interactions

•

59587

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0031356

DRSC - Results from RNAi screens.

•

FBgn0031356

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0031356

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17660-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0031356

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33347

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33347

modMine - Data generated by the modENCODE project.

•

FBgn0031356

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG17660

(Keleman et al., 2009.8.5)

Name Synonym

Secondary FlyBase IDs

References ( 13 )

Research paper

Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784: GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834]
Collier et al., 2005, Genetics 169(4): 2035--2045: The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis. [FBrf0187636]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project: DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]