dFezf, dfezl
zinc finger transcription factor - functions cell-autonomously to maintain the restricted developmental potential of the intermediate neural progenitors generated by type II neuroblasts in Drosophila larval brains
Please see the JBrowse view of Dmel\erm for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 6.01
Gene model reviewed during 5.47
Gene model reviewed during 5.44
Double stop-codon suppression (UGA, UGA) postulated; FBrf0216884.
Gene model reviewed during 6.02
None of the polypeptides share 100% sequence identity.
Found in a probable chromatin remodeling Brahma-associated proteins (BAP) complex composed of at least brm, Bap60, Snr1 and erm. Within the complex, interacts (via N-terminus) with Bap60 and HDAC3.
The second, third and fourth zinc finger domains are necessary for repressing gene transcription.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\erm using the Feature Mapper tool.
Comment: maternally deposited
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
erm is expressed as a dorsal and lateral stripe in blastoderm embryos. The lateral ends of this stripe widen, making the pattern resemble earmuffs. In early germband extension embryos, the stripe is split at the dorsal midline generating bilaterally symmetrical domains. In later embyronic stages, erm-expressing cells delaminate and cluster to form part of the brain hemispheres. The expression domain of mirr abuts the erm expression domain in a complementary pattern.
Comment: 1-2h APF
Comment: 20h APF
Comment: 40h APF
GBrowse - Visual display of RNA-Seq signals
View Dmel\erm in GBrowse 22-3
2-3.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: erm CG31670
Source for merge of: CG7312 CG31670
Source for merge of CG7312 CG31670 was a shared cDNA ( date:030728 ).
Duplicate transcripts identified and eliminated during the migration of annotations from the release 5 genome assembly to the release 6 assembly.
Annotation CG7312 renamed CG31670 in release 3 of the genome annotation.