Gene Dmel\CG3605

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General Information

Symbol

Dmel\CG3605

Species

D. melanogaster

Name

Annotation symbol

CG3605

Feature type

protein_coding_gene

FlyBase ID

FBgn0031493

Gene Model Status

Current

Stock availability

4 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

23C4-23C4

Sequence location

2L:3,026,533..3,029,189 [-]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG3605 (FBgn0031493). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process: nuclear mRNA splicing, via spliceosome. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Domain of unknown function DUF382; PSP, proline-rich. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1638857_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3605. Gene sequence location is 2L:3026533..3029189.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2011_10

FB2012_01

Sequence features

BKN21290

HFA00619

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

23C4-23C4

Limits computationally determined from genome sequence between P{PZ}lilli⁰⁰⁶³² and P{PZ}toc⁰¹³⁶¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG3605 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG3605-RA

FBtr0077669

NM_134895

2424

749

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG3605-PA

FBpp0077353

84.8

749

4.97

NP_608739

AAF51159

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

PSP, proline-rich (IPR006568)

Domain of unknown function DUF382 (IPR007180)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VQK7

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0031493

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	max expr for FBgn0031493
	Very low expression bin max
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No expression (0 - 0)
	Extremely low expression (1 - 10)
	Very low expression (11 - 100)
	Low expression (101 - 400)
	Moderate expression (401 - 1400)
	Moderately high expression (1401 - 4000)
	High expression (4001 - 10000)
	Very high expression (10001 - 100000)
	Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0031493 expression level
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High

Linear, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(5084)
embryo 02-04hr		(8276)
embryo 04-06hr		(8709)
embryo 06-08hr		(6288)
embryo 08-10hr		(5418)
embryo 10-12hr		(3603)
embryo 12-14hr		(3501)
embryo 14-16hr		(2612)
embryo 16-18hr		(1998)
embryo 18-20hr		(1537)
embryo 20-22hr		(1870)
embryo 22-24hr		(1968)
larva L1		(1634)
larva L2		(1512)
larva L3 12hr old		(1160)
larva L3 puffstage 1-2		(1266)
larva L3 puffstage 3-6		(1631)
larva L3 puffstage 7-9		(1965)
white prepupae new		(1937)
white prepupae 12hr		(2088)
white prepupae 24hr		(2457)
pupae 2d postWPP		(1703)
pupae 3d postWPP		(1085)
pupae 4d postWPP		(679)
adult male 01day		(929)
adult male 05day		(1066)
adult male 30day		(1026)
adult female 01day		(1955)
adult female 05day		(3307)
adult female 30day		(3284)
Expression Level Scale		None Extremely low Very low Low

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(5084)
embryo 02-04hr		(8276)
embryo 04-06hr		(8709)
embryo 06-08hr		(6288)
embryo 08-10hr		(5418)
embryo 10-12hr		(3603)
embryo 12-14hr		(3501)
embryo 14-16hr		(2612)
embryo 16-18hr		(1998)
embryo 18-20hr		(1537)
embryo 20-22hr		(1870)
embryo 22-24hr		(1968)
larva L1		(1634)
larva L2		(1512)
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		(1631)
larva L3 puffstage 7-9		(1965)
white prepupae new		(1937)
white prepupae 12hr		(2088)
white prepupae 24hr		(2457)
pupae 2d postWPP		(1703)
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		(1955)
adult female 05day		(3307)
adult female 30day		(3284)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to maximum FBgn0031493 expression level
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(5084)
embryo 02-04hr		(8276)
embryo 04-06hr		(8709)
embryo 06-08hr		(6288)
embryo 08-10hr		(5418)
embryo 10-12hr		(3603)
embryo 12-14hr		(3501)
embryo 14-16hr		(2612)
embryo 16-18hr		(1998)
embryo 18-20hr		(1537)
embryo 20-22hr		(1870)
embryo 22-24hr		(1968)
larva L1		(1634)
larva L2		(1512)
larva L3 12hr old		(1160)
larva L3 puffstage 1-2		(1266)
larva L3 puffstage 3-6		(1631)
larva L3 puffstage 7-9		(1965)
white prepupae new		(1937)
white prepupae 12hr		(2088)
white prepupae 24hr		(2457)
pupae 2d postWPP		(1703)
pupae 3d postWPP		(1085)
pupae 4d postWPP		(679)
adult male 01day		(929)
adult male 05day		(1066)
adult male 30day		(1026)
adult female 01day		(1955)
adult female 05day		(3307)
adult female 30day		(3284)
Expression Level Scale		None Extremely low Very low Low

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(5084)
embryo 02-04hr		(8276)
embryo 04-06hr		(8709)
embryo 06-08hr		(6288)
embryo 08-10hr		(5418)
embryo 10-12hr		(3603)
embryo 12-14hr		(3501)
embryo 14-16hr		(2612)
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		(3307)
adult female 30day		(3284)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		5084
embryo 02-04hr		8276
embryo 04-06hr		8709
embryo 06-08hr		6288
embryo 08-10hr		5418
embryo 10-12hr		3603
embryo 12-14hr		3501
embryo 14-16hr		2612
embryo 16-18hr		1998
embryo 18-20hr		1537
embryo 20-22hr		1870
embryo 22-24hr		1968
larva L1		1634
larva L2		1512
larva L3 12hr old		1160
larva L3 puffstage 1-2		1266
larva L3 puffstage 3-6		1631
larva L3 puffstage 7-9		1965
white prepupae new		1937
white prepupae 12hr		2088
white prepupae 24hr		2457
pupae 2d postWPP		1703
pupae 3d postWPP		1085
pupae 4d postWPP		679
adult male 01day		929
adult male 05day		1066
adult male 30day		1026
adult female 01day		1955
adult female 05day		3307
adult female 30day		3284
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

FlyAtlas Anatomical Expression Data for FBgn0031493

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	max expr for FBgn0031493
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0031493 expression level
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High Very high

log, scaled to maximum FBgn0031493 expression level
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		403.15
Larval Midgut		72.9
Larval Hindgut		124.4
Larval Malpighian Tubules		108.4
Larval Fat Body		121.2
Larval Salivary Gland		173.8
Larval Trachea		209.3
Larval Carcass		151.425
Adult Head		106.6
Adult Eye		161.425
Adult Brain		170.4
Adult Thoracic-Abdominal Ganglion		153.2
Adult Crop		127.5
Adult Midgut		83.9
Adult Hindgut		115
Adult Malpighian Tubules		162.3
Adult Fat Body		110.9
Adult Salivary Gland		140.5
Adult Heart		84.825
Adult VirginFemale Spermatheca		189.6
Adult InseminatedFemale Spermatheca		201.8
Adult Ovary		340.6
Adult Testis		96
Adult Male Accessory Gland		189.5
Adult Carcass		97.1
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	106.6
NA	Eye	161.425
NA	Brain	170.4
403.15	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	153.2
NA	Crop	127.5
72.9	Midgut	83.9
124.4	Hindgut	115
108.4	Malpighian Tubules	162.3
121.2	Fat Body	110.9
173.8	Salivary Gland	140.5
NA	Heart	84.825
209.3	Trachea	NA
NA	VirginFemale Spermatheca	189.6
NA	InseminatedFemale Spermatheca	201.8
NA	Ovary	340.6
NA	Testis	96
NA	Male Accessory Gland	189.5
151.425	Carcass	97.1

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_17

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0031493

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG3605-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG3605

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

CG3605^GD11027

lethal | pupal stage, with Scer\GAL4^pnr-MD237

CG3605^GD11027

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG3605	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG3605	Mutagen	Stocks	Known lesion
CG3605^GD11027	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG3605^HMS00056	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG3605^KK101239	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel7014

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD11027}

P{KK101239}

P{TRiP.HMS00056}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap

P{lacW}l(2)SH1024^SH1024

Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )

Terms Based on Experimental Evidence ( 2 terms )

Molecular Function ( 0 terms)

Biological Process ( 0 terms)

Cellular Component

CV term

Evidence

References

catalytic step 2 spliceosome

inferred from direct assay

(Herold et al., 2009)

precatalytic spliceosome

inferred from direct assay

(Herold et al., 2009)

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

nuclear mRNA splicing, via spliceosome

inferred by curator from GO:0071011|GO:0071013

(Herold et al., 2009)

inferred from sequence or structural similarity with NCBI:NP_006833 AND inferred from sequence or structural similarity with Saccharomyces CUS1

(Mount and Salz, 2000)

inferred from sequence or structural similarity with UniProtKB:Q13435

(FlyBase, 1992-)

Cellular Component

CV term

Evidence

References

spliceosomal complex

inferred from sequence or structural similarity with UniProtKB:Q13435

(FlyBase, 1992-)

U2 snRNP

inferred from sequence or structural similarity with NCBI:NP_006833 AND inferred from sequence or structural similarity with Saccharomyces CUS1

(Mount and Salz, 2000)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG3605 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

59732

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0031493

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33514

Orthologs

Genome-wide drosophilid orthologs

Dana\GF14752

Dere\GG24466

Dgri\GH10339

Dmoj\GI17098

Dper\GL19575

Dpse\GA17553

Dsec\GM18174

Dsim\GD22787

Dvir\GJ10895

Dwil\GK14958

Dyak\GE14955

Curated drosophilid orthologs

Dpse\GA17553

Linkouts

InParanoid A subset of ortholog calls from InParanoid.

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AAEL006725-PA
Aedes aegypti (mosquito)
AGAP006240-PA
Anopheles gambiae (mosquito)
XP_001122081.1
Apis mellifera (honey bee)
XP_001951764.1
Acyrthosiphon pisum (pea aphid)
At4g21660.1
Arabidopsis thaliana (wall cress)
35091
Batrachochytrium dendrobatidis (chytrid fungus)
269858
Branchiostoma floridae (lancelet)
XP_001902937.1
Brugia malayi (roundworm nematode)
BGIBMGA004823-PA
Bombyx mori (silk worm)
ENSBTAP00000051983
Bos taurus (bovine)
CAL0000205
Candida albicans (a form of yeast)
CN00545
Caenorhabditis brenneri (small nematode)
CBP01686
Caenorhabditis briggsae (nematode)
CE14540
Caenorhabditis elegans (worm)
ENSCAFP00000019222
Canis familiaris (dog)
Chro.20372
Cryptosporidium hominis (obligate parasite)
ENSCINP00000011728
Ciona intestinalis (sea squirt)
JA10603
Caenorhabditis japonica (nematode)
cn07167
Cryptococcus neoformans (yeast-like fungus)
cgd2_3510
Cryptosporidium parvum (protozoan parasite)
CPIJ010596
Culex pipens (mosquito)
ENSCPOP00000007457
Cavia porcellus (guinea pig)
123204
Chlamidomonas reinhardtii (green alga)
RP22765
Caenorhabditis remanei (nematode)
ENSCSAVP00000003411
Ciona savignyi (sedentary tunicate)
151106
Capitella spl (polychaete worm)
DDB0233170
Dictyostelium discoideum (amoeba)
DEHA2G06072g
Debaryomyces Hansenii (yeast)
187692
Daphnia pulex (daphnia)
ENSDARP00000076285
Danio rerio (zebra fish)
ENSECAP00000022125
Equus caballus (horse)
XP_650882
Entamoeba histolytica (anaerobic protozoan)
ENSGACP00000025140
Gymnopilus aculeatus (mushroom)
100627
Hypsipyla robusta (cedar shoot borer)
ENSP00000318861
Homo sapiens (human)
ISCW006575-PA
Ixodes scapularis (deer tick)
KLLA0F08481g
Kluyveromyces lactis (yeast)
178463
Lottia gigantea (owl limpet)
37714
Monocosta brevicollis (choanoflagellate)
ENSMODP00000032999
Monodelphis domestica (gray opossum)
ENSMMUP00000015408
Macaca mulatta (rhesus monkey)
ENSMUSP00000025774
Mus musculus (house mouse)
186750
Nematostella vectensis (starlet anemone)
XP_001603552.1
Nasonia vitripennis (wasp)
ENSOANP00000019745
Ornithorynchus anatinus (platypus)
ENSORLP00000010339
Oryzias latipes (japanese killifish)
LOC_Os02g58090.1
Oryza sativa (asian rice)
8195
Ostreococcus tauri (green alga)
PF14_0587
Plasmodium falciparum (protozoal parasite)
PHUM008007-PA
Pediculus humanus (human body louse)
PP27483
Pristionchus pacificus (nematode)
201031
Physcomitrella patens (moss)
ENSPPYP00000003511
Pongo pygmaeus (orangutan)
79152
Phytophthora ramorum (sudden oak death pathogen)
143586
Phytophthora sojae (root rot pathogen)
771129
Populus trichocarpa (black cottonwood)
ENSPTRP00000006745
Pan troglodytes (chimpanzee)
PVX_117375
Plasmodium vivax (protozoal parasite)
ENSRNOP00000027668
Rattus norvegicus (norway rat)
5062348
Sorghum bicolor (sorghum)
YMR240C
Saccharomyces cerevisiae (budding yeast)
Smp_096810.2
Schistosoma mansoni (trematode parasite)
SPAC22F8.10c
Schizosaccharomyces pombe (fission yeast)
XP_001183815.1
Strongylocentrotus purpuratus (purple sea urchin)
20192
Trichoplax adhaerens (metazoa)
TA04540
Theileria annulata (apicomplexan parasite)
XP_975513.2
Tribolium castaneum (red flour beetle)
Tc00.1047053504071.50
Trypanosoma cruzi (parasitic trypanosome)
ENSTNIP00000010247
Tetraodon nigroviridis (green spotted pufferfish)
TP03_0436
Theileria parva (parasitic protozoan)
269780
Thalassiosira pseudonana (marine diatom)
ENSTRUP00000018876
Takifugu rubripes (pufferfish Takifugu)
1.m00933
Tetrahymena thermophila (ciliate protozoa)
82952.m00142
Trichomonas vaginalis (parasitic flagellated protozoan)
ENSXETP00000018449
Xenopus tropicalis (frog)
YALI0D05577g
Yarrowia lipolytica (nonconventional yeast)

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Bloomington

33651

y¹ sc^* v¹; P{TRiP.HMS00056}attP2

VDRC

v105639

P{KK101239}VIE-260B

v26250

w¹¹¹⁸; P{GD11027}v26250

v26252

w¹¹¹⁸; P{GD11027}v26252

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 147 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD45152

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0031493

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33514

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

FlyBase curator comment: the insertion in the "e03045" Exelixis line (PBac{RB}CG17219^e03045) was originally assigned to the CG3605 gene in FBrf0179797, resulting in the "CG3605^e03045" (FBal0161487) allele. However, FBrf0184340 shows that the insertion is actually within CG17219.

(Bloomington Drosophila Stock Center, 2004.11.6)

Other Comments

Identified in an RNAi screen for host factors that alter infection of SL2 cells by L.monocytogenes.

(Agaisse et al., 2005)

Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells.

(Nybakken et al., 2005)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•