• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\sec5

General Information
Symbol	Dmel\sec5	Species	D. melanogaster
Name	sec5	Annotation symbol	CG8843
Feature type	protein_coding_gene	FlyBase ID	FBgn0031537
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	23F3-23F3	Sequence location	2L:3,457,329..3,460,371 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene sec5 is referred to in FlyBase by the symbol Dmel\sec5 (CG8843, FBgn0031537). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: innate immune response; border follicle cell migration; negative regulation of gene expression; cytokinesis; oocyte development; endocytic recycling; cellularization; branch fusion, open tracheal system. 9 alleles are reported. The phenotypes of these alleles are annotated with: A1-7 ventral longitudinal muscle 3; embryonic/larval dorsal branch 1; embryonic/larval dorsal branch 3; bouton; dorsal branch primordium; embryonic/larval dorsal branch 2; border follicle cell; embryonic/larval dorsal branch 4; embryonic/larval dorsal branch 5; neurite. It has one annotated transcript and one annotated polypeptide. Protein features are: Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult salivary gland, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1629189_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of sec5. Gene sequence location is 2L:3457329..3460371.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Controlled Vocabulary Terms negative regulation of gene expression Sequence features BKN27586 HFA00714
FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 22 of adulthood day 20 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 23F3-23F3   Limits computationally determined from genome sequence between P{lacW}Madk00237 and P{lacW}Pdswk10101
Experimentally Determined Cytological Location
Cytogenetic map Notes References 23F-24A   Determined by comparing Celera genomic sequence with sequence from BDGP BAC and P1 clones.   (Lloyd et al., 2000)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sec5 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sec5-RA FBtr0077519  NM_134936   2862   894
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sec5-PA   FBpp0077208   100.7   894   5.62     NP_608780   AAF51106
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cell surface receptor IPT/TIG (IPR002909) Immunoglobulin-like fold (IPR013783) Immunoglobulin E-set (IPR014756)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696244   AE014134 AAF51106   AI133897   AI405361   AI532099   AW944311   AY069793 AAL39938   BF492569   BF492570   BG633658   BI165469   BI215227   BI632854   BI636915   BI640309   CK660349   CO321373   CO340395   EC246420   EC247205   EC255837
UniProtKB/Swiss-Prot	Q9VQQ9
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031537    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031537 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031537 expression level Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1542) embryo 02-04hr  (545) embryo 04-06hr  (917) embryo 06-08hr  (1281) embryo 08-10hr  (1301) embryo 10-12hr  (1634) embryo 12-14hr  (1018) embryo 14-16hr  (833) embryo 16-18hr  (696) embryo 18-20hr  (766) embryo 20-22hr  (634) embryo 22-24hr  (693) larva L1  (714) larva L2  (754) larva L3 12hr old  (751) larva L3 puffstage 1-2  (774) larva L3 puffstage 3-6  (921) larva L3 puffstage 7-9  (1030) white prepupae new  (1053) white prepupae 12hr  (1194) white prepupae 24hr  (1264) pupae 2d postWPP  (832) pupae 3d postWPP  (626) pupae 4d postWPP  (509) adult male 01day  (765) adult male 05day  (859) adult male 30day  (843) adult female 01day  (917) adult female 05day  (1178) adult female 30day  (1279) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1542) embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr  (1634) embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031537 expression level Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1542) embryo 02-04hr  (545) embryo 04-06hr  (917) embryo 06-08hr  (1281) embryo 08-10hr  (1301) embryo 10-12hr  (1634) embryo 12-14hr  (1018) embryo 14-16hr  (833) embryo 16-18hr  (696) embryo 18-20hr  (766) embryo 20-22hr  (634) embryo 22-24hr  (693) larva L1  (714) larva L2  (754) larva L3 12hr old  (751) larva L3 puffstage 1-2  (774) larva L3 puffstage 3-6  (921) larva L3 puffstage 7-9  (1030) white prepupae new  (1053) white prepupae 12hr  (1194) white prepupae 24hr  (1264) pupae 2d postWPP  (832) pupae 3d postWPP  (626) pupae 4d postWPP  (509) adult male 01day  (765) adult male 05day  (859) adult male 30day  (843) adult female 01day  (917) adult female 05day  (1178) adult female 30day  (1279) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr  1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1542 embryo 02-04hr    545 embryo 04-06hr    917 embryo 06-08hr    1281 embryo 08-10hr    1301 embryo 10-12hr    1634 embryo 12-14hr    1018 embryo 14-16hr    833 embryo 16-18hr    696 embryo 18-20hr    766 embryo 20-22hr    634 embryo 22-24hr    693 larva L1    714 larva L2    754 larva L3 12hr old    751 larva L3 puffstage 1-2    774 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1030 white prepupae new    1053 white prepupae 12hr    1194 white prepupae 24hr    1264 pupae 2d postWPP    832 pupae 3d postWPP    626 pupae 4d postWPP    509 adult male 01day    765 adult male 05day    859 adult male 30day    843 adult female 01day    917 adult female 05day    1178 adult female 30day    1279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031537    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031537 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult salivary gland, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031537 expression level Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031537 expression level Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    72.1 Larval Midgut    86.7 Larval Hindgut    72.6 Larval Malpighian Tubules    81.6 Larval Fat Body    54.9 Larval Salivary Gland    116.5 Larval Trachea    71.175 Larval Carcass    58.625 Adult Head    62.3 Adult Eye    94.95 Adult Brain    119.9 Adult Thoracic-Abdominal Ganglion    110.7 Adult Crop    54.1 Adult Midgut    68.4 Adult Hindgut    65.1 Adult Malpighian Tubules    87.7 Adult Fat Body    51.3 Adult Salivary Gland    131.4 Adult Heart    61.075 Adult VirginFemale Spermatheca    48.2 Adult InseminatedFemale Spermatheca    48.2 Adult Ovary    52.9 Adult Testis    43.6 Adult Male Accessory Gland    106.2 Adult Carcass    62.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    62.3   NA  Eye    94.95   NA  Brain    119.9   72.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    110.7   NA  Crop    54.1   86.7  Midgut    68.4   72.6  Hindgut    65.1   81.6  Malpighian Tubules    87.7   54.9  Fat Body    51.3   116.5  Salivary Gland    131.4   NA  Heart    61.075   71.175  Trachea    NA   NA  VirginFemale Spermatheca    48.2   NA  InseminatedFemale Spermatheca    48.2   NA  Ovary    52.9   NA  Testis    43.6   NA  Male Accessory Gland    106.2   58.625  Carcass    62.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031537 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8843-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for sec5 Stages(s) 1-3 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele cell lethal | recessive | somatic clone sec5E10 sec5E13 cell lethal | somatic clone | heat sensitive sec5E10 lethal | larval stage (with Df(2L)tim-02) sec5E10 lethal | larval stage | recessive sec5E10 lethal | pupal stage, with Scer\GAL4pnr-MD237 sec5GD13789 lethal | recessive sec5ts1 Sterility Allele female fertile | germline clone sec5E13 female sterile | germline clone sec5E10 Other Phenotypes Allele visible | dominant sec5E10 visible | recessive sec5E10 sec5E13 visible | recessive | somatic clone sec5E10 sec5E13 visible | somatic clone sec5E10 sec5E13 visible | somatic clone | heat sensitive sec5ts1 Phenotype manifest in Allele A1-7 ventral longitudinal muscle 3 sec5E10 border follicle cell, with Scer\GAL4c306 sec5GD13789 bouton sec5E10 clathrin-coated vesicle & oocyte | germ-line clone sec5E13 coated pit & oocyte | germ-line clone sec5E13 cytoplasmic vesicle & oocyte | germ-line clone sec5E13 dorsal appendage | germline clone sec5E13 dorsal branch primordium sec5E10 sec5E13 egg | germline clone sec5E13 embryo | embryonic stage 5 | germline clone | non-rescuable maternal effect sec5ts1 embryonic/larval dorsal branch 1 sec5E10 embryonic/larval dorsal branch 2 sec5E10 embryonic/larval dorsal branch 3 sec5E10 embryonic/larval dorsal branch 4 sec5E10 embryonic/larval dorsal branch 5 sec5E10 eye | somatic clone sec5E10 sec5E13 eye | somatic clone | heat sensitive sec5ts1 eye photoreceptor cell | somatic clone | heat sensitive sec5ts1 female germline cell | germline clone sec5E10 follicle cell | germline clone sec5E10 furrow canal | germline clone | non-rescuable maternal effect sec5ts1 Golgi stack | germline clone sec5E13 mesothoracic tergum | P-stage | somatic clone sec5E10 neurite sec5E10 nurse cell & actin filament | germ-line clone sec5E10 nurse cell & plasma membrane | germ-line clone sec5E10 sec5E13 nurse cell ring canal | germline clone sec5E10 oocyte | germline clone sec5E10 oocyte nucleus | germline clone sec5E13 polar follicle cell | germline clone sec5E10 recycling endosome | somatic clone sec5E10 ring canal | germline clone sec5E13 yolk | germline clone sec5E13
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of sec5 Class Mutagen Stocks Known lesion sec5E10 loss of function allele ethyl methanesulfonate 0 Yes sec5E13 hypomorphic allele - genetic evidence ethyl methanesulfonate 0 Yes sec5ts1 ethyl methanesulfonate 0 Yes sec5unspecified 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sec5 Class Mutagen Stocks Known lesion sec5GD13789 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes sec5JF02676 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sec5+t11.0 in vitro construct - genomic fragment 0 Yes sec5dsRNA.cSa in vitro construct - RNAi 0 Yes sec5Scer\UAS.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7016 (Ryder, 2004.4.26) Df(2L)tim-02 (Murthy et al., 2003)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13789} NA P{TRiP.JF02676} NA P{UAS-sec5-GFP} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 21 unique terms )
Terms Based on Experimental Evidence ( 17 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
border follicle cell migration inferred from mutant phenotype (Assaker et al., 2010) branch fusion, open tracheal system inferred from mutant phenotype (Jiang et al., 2007, Kakihara et al., 2008) cellularization inferred from mutant phenotype (Murthy et al., 2010) cytokinesis inferred from mutant phenotype (Echard et al., 2004) endocytic recycling inferred from mutant phenotype (Sommer et al., 2005) innate immune response inferred from direct assay (Chien, 2006) negative regulation of gene expression inferred from direct assay (Anderson et al., 2006) oocyte development inferred from mutant phenotype (Sommer et al., 2005)
Cellular Component
CV term Evidence References
annulate lamellae inferred from direct assay (Jiang et al., 2007) clathrin-coated vesicle inferred from direct assay (Sommer et al., 2005) coated pit inferred from direct assay (Sommer et al., 2005) cytoplasm inferred from direct assay (Murthy et al., 2010, Sommer et al., 2005) exocyst inferred from physical interaction with exo84 (Sommer et al., 2005) inferred from physical interaction with sec3 (Sommer et al., 2005) inferred from physical interaction with sec6 (Sommer et al., 2005) plasma membrane inferred from direct assay (Beronja et al., 2005, Sommer et al., 2005, Murthy et al., 2005) colocalizes_with recycling endosome inferred from mutant phenotype (Langevin et al., 2005) rhabdomere inferred from direct assay (Beronja et al., 2005) subapical complex inferred from direct assay (Murthy et al., 2010)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurotransmitter secretion non-traceable author statement (Lloyd et al., 2000) synaptic vesicle docking involved in exocytosis inferred from sequence or structural similarity with UniProtKB:Q96KP1 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000) synaptic vesicle targeting inferred from sequence or structural similarity with UniProtKB:Q96KP1 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000) vesicle-mediated transport inferred from sequence or structural similarity (Littleton, 2000)
Cellular Component
CV term Evidence References
exocyst inferred from sequence or structural similarity (Littleton, 2000) inferred from sequence or structural similarity with EMBL:AF032666 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:Q96KP1 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sec5 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59774 DroID - A comprehensive database of gene and protein interactions. • FBgn0031537 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33563
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21589 Dere\GG24944 Dgri\GH11584 Dmoj\GI17153 Dper\GL19244 Dpse\GA21362 Dsec\GM11139 Dsim\GD23233 Dvir\GJ17657 Dwil\GK23817 Dyak\GE18235
Curated drosophilid orthologs	Dpse\GA21362
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009926-PA Aedes aegypti (mosquito) AGAP001733-PA Anopheles gambiae (mosquito) XP_001122322.1 Apis mellifera (honey bee) XP_001948107.1 Acyrthosiphon pisum (pea aphid) At1g76850.1 Arabidopsis thaliana (wall cress) 92165 Batrachochytrium dendrobatidis (chytrid fungus) 214268 Branchiostoma floridae (lancelet) XP_001902796.1 Brugia malayi (roundworm nematode) BGIBMGA003392-PA Bombyx mori (silk worm) ENSBTAP00000026920 Bos taurus (bovine) CBP00233 Caenorhabditis briggsae (nematode) CE03705 Caenorhabditis elegans (worm) ENSCAFP00000013512 Canis familiaris (dog) ENSCINP00000004984 Ciona intestinalis (sea squirt) cn01705 Cryptococcus neoformans (yeast-like fungus) CPIJ001674 Culex pipens (mosquito) ENSCPOP00000003255 Cavia porcellus (guinea pig) RP38657 Caenorhabditis remanei (nematode) 104603 Capitella spl (polychaete worm) DDB0233961 Dictyostelium discoideum (amoeba) 300804 Daphnia pulex (daphnia) ENSDARP00000072428 Danio rerio (zebra fish) ENSGACP00000006604 Gymnopilus aculeatus (mushroom) ENSGALP00000020908 Gallus gallus (chicken) 193281 Hypsipyla robusta (cedar shoot borer) ENSP00000230449 Homo sapiens (human) ISCW006643-PA Ixodes scapularis (deer tick) 108931 Lottia gigantea (owl limpet) ENSMODP00000034757 Monodelphis domestica (gray opossum) ENSMMUP00000031011 Macaca mulatta (rhesus monkey) ENSMUSP00000100010 Mus musculus (house mouse) 247537 Nematostella vectensis (starlet anemone) XP_001606239.1 Nasonia vitripennis (wasp) ENSOANP00000010111 Ornithorynchus anatinus (platypus) ENSORLP00000015862 Oryzias latipes (japanese killifish) LOC_Os04g34450.1 Oryza sativa (asian rice) PHUM001000-PA Pediculus humanus (human body louse) 122743 Physcomitrella patens (moss) ENSPPYP00000018078 Pongo pygmaeus (orangutan) 798630 Populus trichocarpa (black cottonwood) ENSPTRP00000030163 Pan troglodytes (chimpanzee) ENSRNOP00000050367 Rattus norvegicus (norway rat) 5057193 Sorghum bicolor (sorghum) Smp_131960 Schistosoma mansoni (trematode parasite) XP_001201201.1 Strongylocentrotus purpuratus (purple sea urchin) 55542 Trichoplax adhaerens (metazoa) XP_966441.1 Tribolium castaneum (red flour beetle) ENSTNIP00000003258 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000004182 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000024906 Xenopus tropicalis (frog) YALI0A19052g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16183 NV13029 LH20968 LH10038 ISCW006643 FBgn0235664 FBgn0225779 FBgn0204826 FBgn0194622 FBgn0177455 FBgn0166084 JGI_V11_300804 FBgn0081350 FBgn0156843 FBgn0139897 FBgn0119064 FBgn0117073 FBgn0098589 CPIJ001674 BGIBMGA003392 ACYPI009381 GB16409 AGAP001733 AAEL009926 PHUM379640 GLEAN_04683
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	27526 y1 v1; P{TRiP.JF02676}attP2
VDRC	v28873 w1118; P{GD13789}v28873 v28874 w1118; P{GD13789}v28874
Genomic Clones ( 2 )
	BACR03G07 BACR26A07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 13 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD03467
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH10912 GH25338 LP18846 RE05377 RE21569 SD18760 SD23132 SD26741
Other clones	AT01067 EK185545 EP10550 GM05361
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031537 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33563
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: sec5 CG8843 (Verstreken and Bellen, 2000.9.4)
Source for database merge of
Additional comments
Other Comments
	S2 cells treated with dsRNA directed against sec5 show normal binding and internalization of E.coli and normal binding but significantly decreased internalization of S.aureus in a phagocytosis assay. (Stuart et al., 2007) The sec5 product negatively regulates dac expression in the embryonic head. (Anderson et al., 2006) sec5 heterozygotes are viable but exhibit a reduced immune response to fungal invasion. (Chien, 2006) In sec5 mutant epithelial cells, lateral shg protein is not recycled to the adherens junctions but instead accumulates in recycling endosomes. (Langevin et al., 2005) dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells. (Echard et al., 2004) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134936 RefSeq (Proteins) • NP_608780 DDBJ / EMBL / GenBank • AAF51106 AAL39938 AI532099 AW944311 AY069793 Entrez Gene - A searchable database of RefSeq genes. • 33563 UniProtKB/Swiss-Prot • Q9VQQ9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cell surface receptor IPT/TIG (IPR002909) Immunoglobulin-like fold (IPR013783) Immunoglobulin E-set (IPR014756)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59774 DroID - A comprehensive database of gene and protein interactions. • FBgn0031537 DRSC - Results from RNAi screens. • FBgn0031537 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031537 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8843-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031537 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33563 InParanoid A subset of ortholog calls from InParanoid. • AAEL009926-PA Aedes aegypti (mosquito) AGAP001733-PA Anopheles gambiae (mosquito) XP_001122322.1 Apis mellifera (honey bee) XP_001948107.1 Acyrthosiphon pisum (pea aphid) At1g76850.1 Arabidopsis thaliana (wall cress) 92165 Batrachochytrium dendrobatidis (chytrid fungus) 214268 Branchiostoma floridae (lancelet) XP_001902796.1 Brugia malayi (roundworm nematode) BGIBMGA003392-PA Bombyx mori (silk worm) ENSBTAP00000026920 Bos taurus (bovine) CBP00233 Caenorhabditis briggsae (nematode) CE03705 Caenorhabditis elegans (worm) ENSCAFP00000013512 Canis familiaris (dog) ENSCINP00000004984 Ciona intestinalis (sea squirt) cn01705 Cryptococcus neoformans (yeast-like fungus) CPIJ001674 Culex pipens (mosquito) ENSCPOP00000003255 Cavia porcellus (guinea pig) RP38657 Caenorhabditis remanei (nematode) 104603 Capitella spl (polychaete worm) DDB0233961 Dictyostelium discoideum (amoeba) 300804 Daphnia pulex (daphnia) ENSDARP00000072428 Danio rerio (zebra fish) ENSGACP00000006604 Gymnopilus aculeatus (mushroom) ENSGALP00000020908 Gallus gallus (chicken) 193281 Hypsipyla robusta (cedar shoot borer) ENSP00000230449 Homo sapiens (human) ISCW006643-PA Ixodes scapularis (deer tick) 108931 Lottia gigantea (owl limpet) ENSMODP00000034757 Monodelphis domestica (gray opossum) ENSMMUP00000031011 Macaca mulatta (rhesus monkey) ENSMUSP00000100010 Mus musculus (house mouse) 247537 Nematostella vectensis (starlet anemone) XP_001606239.1 Nasonia vitripennis (wasp) ENSOANP00000010111 Ornithorynchus anatinus (platypus) ENSORLP00000015862 Oryzias latipes (japanese killifish) LOC_Os04g34450.1 Oryza sativa (asian rice) PHUM001000-PA Pediculus humanus (human body louse) 122743 Physcomitrella patens (moss) ENSPPYP00000018078 Pongo pygmaeus (orangutan) 798630 Populus trichocarpa (black cottonwood) ENSPTRP00000030163 Pan troglodytes (chimpanzee) ENSRNOP00000050367 Rattus norvegicus (norway rat) 5057193 Sorghum bicolor (sorghum) Smp_131960 Schistosoma mansoni (trematode parasite) XP_001201201.1 Strongylocentrotus purpuratus (purple sea urchin) 55542 Trichoplax adhaerens (metazoa) XP_966441.1 Tribolium castaneum (red flour beetle) ENSTNIP00000003258 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000004182 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000024906 Xenopus tropicalis (frog) YALI0A19052g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /hjmuller/sec5-1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33563 modMine - Data generated by the modENCODE project. • FBgn0031537 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16183 NV13029 LH20968 LH10038 ISCW006643 FBgn0235664 FBgn0225779 FBgn0204826 FBgn0194622 FBgn0177455 FBgn0166084 JGI_V11_300804 FBgn0081350 FBgn0156843 FBgn0139897 FBgn0119064 FBgn0117073 FBgn0098589 CPIJ001674 BGIBMGA003392 ACYPI009381 GB16409 AGAP001733 AAEL009926 PHUM379640 GLEAN_04683
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG8843 (Stuart et al., 2007, Gandhi et al., 2007, Perkins et al., 2009, Cammarato et al., 2011) dsec5 (Lloyd et al., 2000) Sec-5 (Kirby et al., 2004) Sec5 (Littleton, 2000, Chien, 2006, Beronja et al., 2005, Sommer et al., 2005, Sommer et al., 2005, Shimada et al., 2006, Lee and Cooley, 2007, Raja et al., 2010) sec5 (Anderson et al., 2006, Stuart et al., 2007, Mehta et al., 2005, Mehta, 2005, Classen et al., 2005, Coutelis and Ephrussi, 2007, Langevin et al., 2005, Kakihara et al., 2008, van IJzendoorn, 2006, Murthy et al., 2005, Jiang et al., 2007, Leibfried et al., 2008, Blankenship et al., 2007, Kelkar and Dobberstein, 2009, Murthy et al., 2010, Assaker et al., 2010, Seong et al., 2011, Windler and Bilder, 2010, Andersen et al., 2010) Sec5p (Littleton, 2000)
Name Synonym	sec5 (Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 55 )
Generate a list of	All references relating to this gene ( 55 )
List References by type	Research paper  ( 30 ) Supplementary material  ( 8 ) Review  ( 3 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 5 ) FlyBase analysis  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 7 )
	Michel et al., 2011, Nat. Commun. 2: 415 Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. [FBrf0214604] Seong et al., 2011, Biogerontology 12(2): 93--107 Genome-wide analysis of low-dose irradiated male Drosophila melanogaster with extended longevity. [FBrf0213307] Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Drosophila MCRS2 Associates with RNA Polymerase II Complexes To Regulate Transcription. [FBrf0211794] Assaker et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(52): 22558--22563 Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. [FBrf0212585] Murthy et al., 2010, Development 137(16): 2773--2783 Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization. [FBrf0211434] Raja et al., 2010, Mol. Cell 38(6): 827--841 The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila. [FBrf0211222] Windler and Bilder, 2010, Curr. Biol. 20(6): 538--543 Endocytic internalization routes required for delta/notch signaling. [FBrf0210409] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...