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Gene Dmel\CG15443

General Information
Symbol	Dmel\CG15443	Species	D. melanogaster
Name		Annotation symbol	CG15443
Feature type	protein_coding_gene	FlyBase ID	FBgn0031609
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	24F3-24F3	Sequence location	2L:4,461,657..4,462,994 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG15443 (FBgn0031609). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding. There is experimental evidence that it is involved in the biological process: lateral inhibition. 8 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; chaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-like helical; Armadillo-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1636352_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG15443. Gene sequence location is 2L:4461657..4462994.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN45772 BKN26775 HFA00455
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 24F3-24F3   Limits computationally determined from genome sequence between P{lacW}Tps1k08903&P{EP}morgueEP1184 and P{lacW}l(2)k10004k10004&P{EP}CG3036EP963
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG15443 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG15443-RA FBtr0077450  NM_134995   1278   358
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG15443-PA   FBpp0077140   40.0   358   7.84     NP_608839   AAF51004
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA538645   AA695902   AE014134 AAF51004   AI386670   BI162209   BI162210   BI619955   BT015957 AAV36842   CO272583   CO272762   CO276238   CO292118   CZ480007   CZ481576   EC060398   EC075049   EC208946   EC209251   ES689525
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VR04
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031609    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031609 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031609 expression level Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1831) embryo 02-04hr  (2066) embryo 04-06hr  (1620) embryo 06-08hr  (1382) embryo 08-10hr  (1217) embryo 10-12hr  (1139) embryo 12-14hr  (714) embryo 14-16hr  (632) embryo 16-18hr  (491) embryo 18-20hr  (411) embryo 20-22hr  (420) embryo 22-24hr  (442) larva L1  (530) larva L2  (436) larva L3 12hr old  (348) larva L3 puffstage 1-2  (482) larva L3 puffstage 3-6  (597) larva L3 puffstage 7-9  (784) white prepupae new  (727) white prepupae 12hr  (728) white prepupae 24hr  (837) pupae 2d postWPP  (669) pupae 3d postWPP  (486) pupae 4d postWPP  (468) adult male 01day  (590) adult male 05day  (728) adult male 30day  (716) adult female 01day  (743) adult female 05day  (1047) adult female 30day  (1126) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1831) embryo 02-04hr  (2066) embryo 04-06hr  (1620) embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031609 expression level Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1831) embryo 02-04hr  (2066) embryo 04-06hr  (1620) embryo 06-08hr  (1382) embryo 08-10hr  (1217) embryo 10-12hr  (1139) embryo 12-14hr  (714) embryo 14-16hr  (632) embryo 16-18hr  (491) embryo 18-20hr  (411) embryo 20-22hr  (420) embryo 22-24hr  (442) larva L1  (530) larva L2  (436) larva L3 12hr old  (348) larva L3 puffstage 1-2  (482) larva L3 puffstage 3-6  (597) larva L3 puffstage 7-9  (784) white prepupae new  (727) white prepupae 12hr  (728) white prepupae 24hr  (837) pupae 2d postWPP  (669) pupae 3d postWPP  (486) pupae 4d postWPP  (468) adult male 01day  (590) adult male 05day  (728) adult male 30day  (716) adult female 01day  (743) adult female 05day  (1047) adult female 30day  (1126) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1831 embryo 02-04hr  2066 embryo 04-06hr  1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1831 embryo 02-04hr    2066 embryo 04-06hr    1620 embryo 06-08hr    1382 embryo 08-10hr    1217 embryo 10-12hr    1139 embryo 12-14hr    714 embryo 14-16hr    632 embryo 16-18hr    491 embryo 18-20hr    411 embryo 20-22hr    420 embryo 22-24hr    442 larva L1    530 larva L2    436 larva L3 12hr old    348 larva L3 puffstage 1-2    482 larva L3 puffstage 3-6    597 larva L3 puffstage 7-9    784 white prepupae new    727 white prepupae 12hr    728 white prepupae 24hr    837 pupae 2d postWPP    669 pupae 3d postWPP    486 pupae 4d postWPP    468 adult male 01day    590 adult male 05day    728 adult male 30day    716 adult female 01day    743 adult female 05day    1047 adult female 30day    1126 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031609    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031609 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031609 expression level Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031609 expression level Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    155.875 Larval Midgut    65.2 Larval Hindgut    81.9 Larval Malpighian Tubules    105.6 Larval Fat Body    109.9 Larval Salivary Gland    144.3 Larval Trachea    132.6 Larval Carcass    51.525 Adult Head    79.6 Adult Eye    190.6 Adult Brain    114.3 Adult Thoracic-Abdominal Ganglion    98.3 Adult Crop    93.2 Adult Midgut    69.4 Adult Hindgut    81.8 Adult Malpighian Tubules    92.2 Adult Fat Body    84.2 Adult Salivary Gland    152.1 Adult Heart    86.05 Adult VirginFemale Spermatheca    76.8 Adult InseminatedFemale Spermatheca    73.3 Adult Ovary    205.1 Adult Testis    54.6 Adult Male Accessory Gland    200.9 Adult Carcass    60.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    79.6   NA  Eye    190.6   NA  Brain    114.3   155.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    98.3   NA  Crop    93.2   65.2  Midgut    69.4   81.9  Hindgut    81.8   105.6  Malpighian Tubules    92.2   109.9  Fat Body    84.2   144.3  Salivary Gland    152.1   NA  Heart    86.05   132.6  Trachea    NA   NA  VirginFemale Spermatheca    76.8   NA  InseminatedFemale Spermatheca    73.3   NA  Ovary    205.1   NA  Testis    54.6   NA  Male Accessory Gland    200.9   51.525  Carcass    60.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031609 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15443-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG15443e03827 viable, with Scer\GAL4pnr-MD237 CG15443GD1723 Sterility Allele fertile CG15443e03827 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG15443GD1723 Phenotype manifest in Allele chaeta, with Scer\GAL4pnr-MD237 CG15443GD1723 trichogen cell, with Scer\GAL4pnr-MD237 CG15443GD1723
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of CG15443 Class Mutagen Stocks Known lesion CG15443e03827 piggyBac transposase 2 -- CG15443c03956 1 -- CG15443e02182 piggyBac transposase 1 -- CG15443f03203 1 -- CG15443NP2314 1 -- CG15443c03288 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG15443 Class Mutagen Stocks Known lesion CG15443GD1723 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15443KK106775 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel8011 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1723} NA P{KK106775} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG15443c03288 NA PBac{PB}CG15443c03956 NA PBac{RB}CG15443e02182 NA PBac{RB}CG15443e03827 NA PBac{WH}CG15443f03203 NA insertion of enhancer trap binary system P{GawB}CG15443NP2314 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
lateral inhibition inferred from mutant phenotype (Mummery-Widmer et al., 2009)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG15443 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59850 DroID - A comprehensive database of gene and protein interactions. • FBgn0031609 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33656
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23989 Dere\GG24370 Dgri\GH13129 Dmoj\GI22770 Dper\GL15392 Dpse\GA13734 Dsec\GM18086 Dsim\GD22704 Dvir\GJ23321 Dwil\GK23924 Dyak\GE14709
Curated drosophilid orthologs	Dpse\GA13734
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006407-PA Aedes aegypti (mosquito) XP_001950496.1 Acyrthosiphon pisum (pea aphid) CPIJ004189 Culex pipens (mosquito) ENSTNIP00000000379 Tetraodon nigroviridis (green spotted pufferfish) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16062 NV19001 LH15855 FBgn0232303 FBgn0225886 FBgn0210422 FBgn0194101 FBgn0172993 JGI_V11_311915 FBgn0073770 FBgn0152996 FBgn0145497 FBgn0120606 FBgn0116502 FBgn0100983 CPIJ004189 ACYPI004220 AGAP008299 AAEL006407
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	18198 w1118; PBac{RB}CG15443e03827 11320 w1118; PBac{PB}CG15443c03956 PBac{PB}GRHRc03956
Harvard	- PBac{RB}CG15443e02182 - PBac{RB}CG15443e03827 - PBac{WH}CG15443f03203
Kyoto	104155 w*; P{GawB}CG15443NP2314 / CyO
VDRC	v107438 P{KK106775}VIE-260B v40877 w1118; P{GD1723}v40877
Genomic Clones ( 1 )
	BACR28K16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 9 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH51096
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH16825 GM04743 LD18222
Other clones	EK107715 EK108315 EK120118 EK199236 RE01585
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031609 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33656
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134995 RefSeq (Proteins) • NP_608839 DDBJ / EMBL / GenBank • AAF51004 AAV36842 BI619955 BT015957 CZ480007 CZ481576 Entrez Gene - A searchable database of RefSeq genes. • 33656 UniProtKB/TrEMBL • Q9VR04
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59850 DroID - A comprehensive database of gene and protein interactions. • FBgn0031609 DRSC - Results from RNAi screens. • FBgn0031609 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031609 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15443-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031609 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33656 InParanoid A subset of ortholog calls from InParanoid. • AAEL006407-PA Aedes aegypti (mosquito) XP_001950496.1 Acyrthosiphon pisum (pea aphid) CPIJ004189 Culex pipens (mosquito) ENSTNIP00000000379 Tetraodon nigroviridis (green spotted pufferfish) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33656 modMine - Data generated by the modENCODE project. • FBgn0031609 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16062 NV19001 LH15855 FBgn0232303 FBgn0225886 FBgn0210422 FBgn0194101 FBgn0172993 JGI_V11_311915 FBgn0073770 FBgn0152996 FBgn0145497 FBgn0120606 FBgn0116502 FBgn0100983 CPIJ004189 ACYPI004220 AGAP008299 AAEL006407
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG15443 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Levis and Matthews, 2006.8.8, Sorting out Exelixis multiples. Sorting out Exelixis multiples. [FBrf0195873] Levis, 2005.11.3, Suspect multiple cases, Exelixis lines. Suspect multiple cases, Exelixis lines. [FBrf0191549] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Lasko, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126679]