Ionotropic Receptor (IR) family of variant ionotropic glutamate receptors part of an input pathway to the circadian clock that detects small temperature differences - required for humidity preference - co-receptor subunit in chemosensation and thermosensation
Gene model reviewed during 5.45
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.48
Interacts with nocte.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ir25a using the Feature Mapper tool.
Ir21a protein is detected in cold cell sensory endings. It is also detected in hot cells.
Ir25a protein is expressed in a subset of the neurons of the sensillum coeloconicum of antennal segment 3, aristal sensillum, and basiconic and blunt-tipped sensillum of sacculus, which project to the first and second chambers of the sacculus, respectively. A subset of the sensilla coeloconicum labeled with Ir25a also expresses Ir8a.
Ir25a protein is expressed expression in the adult dorsal and ventral cibarial sense organs and in the labellum. In the larva, it is detected in the terminal organ, hypopharyngeal sense organ (posterior pharyngeal sense organ, PPS) and epiphysis (dorsal pharyngeal sense organ, DPS).
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ir25a in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ir25a CG15627