an F-box protein with leucine-rich repeats (LRRs), a putative component of a SCF E3 ubiquitin ligase complex - essential for resetting the clock by transmitting light signals from Cryptochrome to Timeless resulting in the degredation of Timeless
Gene model reviewed during 5.44
Gene model reviewed during 5.48
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\jet using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\jet in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: jet CG8873
Encodes an F-box protein with leucine-rich repeats.
Mutations in jet result in reduced light sensitivity of the circadian clock: mutant flies show rhythmic behavior in constant light, reduced phase shifts in response to light pulses, and reduced light-dependent degradation of tim protein.
Named "jetlag" because mutants take longer to re-entrain to a new schedule than wild-type flies.