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Gene Dmel\mRpL28

General Information
Symbol	Dmel\mRpL28	Species	D. melanogaster
Name	mitochondrial ribosomal protein L28	Annotation symbol	CG3782
Feature type	protein_coding_gene	FlyBase ID	FBgn0031660
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	25B5-25B5	Sequence location	2L:4,973,978..4,975,284 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mitochondrial ribosomal protein L28 is referred to in FlyBase by the symbol Dmel\mRpL28 (CG3782, FBgn0031660). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. It is reported to be involved in the biological process: translation. 4 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Exoribonuclease, phosphorolytic domain 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult fat body, larval/adult salivary gland, adult female reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult heart, larval fat body, larval trachea, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1640523_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mRpL28. Gene sequence location is 2L:4973978..4975284.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Casad et al., 2011, Genetics 189(3): 861--870 Sequence features BKN21001 HFA02724
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25B5-25B5   Limits computationally determined from genome sequence between P{PZ}l(2)0571405714 and P{lacW}l(2)k10001k10001
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mRpL28 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mRpL28-RA FBtr0078996  NM_135043   1136   302
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mRpL28-PA   FBpp0078635   34.9   302   9.40     NP_608887   AAF52188
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Exoribonuclease, phosphorolytic domain 1 (IPR001247)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA539217   AA539438   AA694748   AA694974   AA802016   AA949234   AA952028   AA978404   AA979268   AE014134 AAF52188   AI063544   AI063632   AI107084   AI108623   AI388682   AY075494 AAL68304   BE977167   BG633557   BI172113   BI214752   BI231280   BI355245   BI357035   BI362970   BI629915   BQ103484   BT030944   CA806941   CO178676   CO281409   CO292030   EC061952   EC205069   EC235512   EC241698   EV585259   GH750578   GH752044   GH752064   GH753268   GH755041   GH757639   GH758644   GH759456   GH759698   GH772322   GH782742   GH784548   GH784863   GH785303   GH786412   GH786443   GH786585   GH790157   GH799521   GH800144   GH801871   GH803158   GH808276   GH811456   GH812114   GH812766   GH815624   GH829253   GH829394   GH829522   GH829712   GH831799   GH832083   GH840205   GH840249   GH848192   GH848982   GH849785   GH850206   GH852327   GH852347   GH855396   GH856205   GH857507   GH861175   GH866438   GH867173   GH868706   GH869794   GH877937   GH879116   GH885042   GH896737   GH901617   GH909616   GH910654   GH912890   GH913050   GH917775   GH918736   GH919260   GH920284   GH930058   GH933614   GH937424   GH937434
UniProtKB/Swiss-Prot	Q9VMX0
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031660    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031660 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031660 expression level Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4405) embryo 02-04hr  (4468) embryo 04-06hr  (2608) embryo 06-08hr  (2709) embryo 08-10hr  (3043) embryo 10-12hr  (4237) embryo 12-14hr  (3726) embryo 14-16hr  (5048) embryo 16-18hr  (5513) embryo 18-20hr  (5911) embryo 20-22hr  (7357) embryo 22-24hr  (7355) larva L1  (7277) larva L2  (7659) larva L3 12hr old  (6270) larva L3 puffstage 1-2  (3875) larva L3 puffstage 3-6  (3261) larva L3 puffstage 7-9  (3181) white prepupae new  (2921) white prepupae 12hr  (2416) white prepupae 24hr  (2473) pupae 2d postWPP  (3872) pupae 3d postWPP  (7369) pupae 4d postWPP  (6569) adult male 01day  (6698) adult male 05day  (5478) adult male 30day  (3748) adult female 01day  (5823) adult female 05day  (4527) adult female 30day  (4584) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4405) embryo 02-04hr  (4468) embryo 04-06hr  (2608) embryo 06-08hr  (2709) embryo 08-10hr  (3043) embryo 10-12hr  (4237) embryo 12-14hr  (3726) embryo 14-16hr  (5048) embryo 16-18hr  (5513) embryo 18-20hr  (5911) embryo 20-22hr  (7357) embryo 22-24hr  (7355) larva L1  (7277) larva L2  (7659) larva L3 12hr old  (6270) larva L3 puffstage 1-2  (3875) larva L3 puffstage 3-6  (3261) larva L3 puffstage 7-9  (3181) white prepupae new  (2921) white prepupae 12hr  (2416) white prepupae 24hr  (2473) pupae 2d postWPP  (3872) pupae 3d postWPP  (7369) pupae 4d postWPP  (6569) adult male 01day  (6698) adult male 05day  (5478) adult male 30day  (3748) adult female 01day  (5823) adult female 05day  (4527) adult female 30day  (4584) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031660 expression level Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4405) embryo 02-04hr  (4468) embryo 04-06hr  (2608) embryo 06-08hr  (2709) embryo 08-10hr  (3043) embryo 10-12hr  (4237) embryo 12-14hr  (3726) embryo 14-16hr  (5048) embryo 16-18hr  (5513) embryo 18-20hr  (5911) embryo 20-22hr  (7357) embryo 22-24hr  (7355) larva L1  (7277) larva L2  (7659) larva L3 12hr old  (6270) larva L3 puffstage 1-2  (3875) larva L3 puffstage 3-6  (3261) larva L3 puffstage 7-9  (3181) white prepupae new  (2921) white prepupae 12hr  (2416) white prepupae 24hr  (2473) pupae 2d postWPP  (3872) pupae 3d postWPP  (7369) pupae 4d postWPP  (6569) adult male 01day  (6698) adult male 05day  (5478) adult male 30day  (3748) adult female 01day  (5823) adult female 05day  (4527) adult female 30day  (4584) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4405) embryo 02-04hr  (4468) embryo 04-06hr  (2608) embryo 06-08hr  (2709) embryo 08-10hr  (3043) embryo 10-12hr  (4237) embryo 12-14hr  (3726) embryo 14-16hr  (5048) embryo 16-18hr  (5513) embryo 18-20hr  (5911) embryo 20-22hr  (7357) embryo 22-24hr  (7355) larva L1  (7277) larva L2  (7659) larva L3 12hr old  (6270) larva L3 puffstage 1-2  (3875) larva L3 puffstage 3-6  (3261) larva L3 puffstage 7-9  (3181) white prepupae new  (2921) white prepupae 12hr  2416 white prepupae 24hr  (2473) pupae 2d postWPP  (3872) pupae 3d postWPP  (7369) pupae 4d postWPP  (6569) adult male 01day  (6698) adult male 05day  (5478) adult male 30day  (3748) adult female 01day  (5823) adult female 05day  (4527) adult female 30day  (4584) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4405 embryo 02-04hr    4468 embryo 04-06hr    2608 embryo 06-08hr    2709 embryo 08-10hr    3043 embryo 10-12hr    4237 embryo 12-14hr    3726 embryo 14-16hr    5048 embryo 16-18hr    5513 embryo 18-20hr    5911 embryo 20-22hr    7357 embryo 22-24hr    7355 larva L1    7277 larva L2    7659 larva L3 12hr old    6270 larva L3 puffstage 1-2    3875 larva L3 puffstage 3-6    3261 larva L3 puffstage 7-9    3181 white prepupae new    2921 white prepupae 12hr    2416 white prepupae 24hr    2473 pupae 2d postWPP    3872 pupae 3d postWPP    7369 pupae 4d postWPP    6569 adult male 01day    6698 adult male 05day    5478 adult male 30day    3748 adult female 01day    5823 adult female 05day    4527 adult female 30day    4584 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031660    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031660 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult fat body, larval/adult salivary gland, adult female reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult heart, larval fat body, larval trachea, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031660 expression level Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut  501.7 Larval Hindgut  (612.1) Larval Malpighian Tubules  (812.7) Larval Fat Body    451.2 Larval Salivary Gland  518.8 Larval Trachea    484.775 Larval Carcass  (573.425) Adult Head  509.4 Adult Eye  (794.275) Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion  (559.6) Adult Crop  (595.9) Adult Midgut  (794.8) Adult Hindgut  (729.3) Adult Malpighian Tubules  (782.1) Adult Fat Body  (693.1) Adult Salivary Gland  (842.4) Adult Heart    484.9 Adult VirginFemale Spermatheca  (705.5) Adult InseminatedFemale Spermatheca  (626.3) Adult Ovary  508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass  (851.7) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031660 expression level Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut  501.7 Larval Hindgut  612.1 Larval Malpighian Tubules  812.7 Larval Fat Body    451.2 Larval Salivary Gland  518.8 Larval Trachea    484.775 Larval Carcass  573.425 Adult Head  509.4 Adult Eye  794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion  559.6 Adult Crop  595.9 Adult Midgut  794.8 Adult Hindgut  729.3 Adult Malpighian Tubules  782.1 Adult Fat Body  693.1 Adult Salivary Gland  (842.4) Adult Heart    484.9 Adult VirginFemale Spermatheca  705.5 Adult InseminatedFemale Spermatheca  626.3 Adult Ovary  508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass  (851.7) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.7 Larval Midgut    501.7 Larval Hindgut    612.1 Larval Malpighian Tubules    812.7 Larval Fat Body    451.2 Larval Salivary Gland    518.8 Larval Trachea    484.775 Larval Carcass    573.425 Adult Head    509.4 Adult Eye    794.275 Adult Brain    411.3 Adult Thoracic-Abdominal Ganglion    559.6 Adult Crop    595.9 Adult Midgut    794.8 Adult Hindgut    729.3 Adult Malpighian Tubules    782.1 Adult Fat Body    693.1 Adult Salivary Gland    842.4 Adult Heart    484.9 Adult VirginFemale Spermatheca    705.5 Adult InseminatedFemale Spermatheca    626.3 Adult Ovary    508.6 Adult Testis    312 Adult Male Accessory Gland    360.1 Adult Carcass    851.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    509.4   NA  Eye    794.275   NA  Brain    411.3   413.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    559.6   NA  Crop    595.9   501.7  Midgut    794.8   612.1  Hindgut    729.3   812.7  Malpighian Tubules    782.1   451.2  Fat Body    693.1   518.8  Salivary Gland    842.4   NA  Heart    484.9   484.775  Trachea    NA   NA  VirginFemale Spermatheca    705.5   NA  InseminatedFemale Spermatheca    626.3   NA  Ovary    508.6   NA  Testis    312   NA  Male Accessory Gland    360.1   573.425  Carcass    851.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_15
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3782-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 mRpL28GD11073 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 mRpL28GD11073 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 mRpL28GD11073
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of mRpL28 Class Mutagen Stocks Known lesion mRpL28G5801 P-element activity 1 -- mRpL28MI00357 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mRpL28 Class Mutagen Stocks Known lesion mRpL28GD11073 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes mRpL28KK100905 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7021 (Ryder, 2004.4.26) Df(2L)Exel8012 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11073} NA P{KK100905} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}mRpL28G5801 NA miscellaneous insertions Mi{MIC}mRpL28MI00357 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with UniProtKB:P36525 (Koc et al., 2001) non-traceable author statement (assigned by UniProtKB) (Swiss-Prot Project Members, 2003.10.10)
Biological Process
CV term Evidence References
translation non-traceable author statement (assigned by UniProtKB) (Swiss-Prot Project Members, 2003.10.10)
Cellular Component
CV term Evidence References
mitochondrial large ribosomal subunit inferred from sequence or structural similarity with UniProtKB:P36525 (Koc et al., 2001) non-traceable author statement (assigned by UniProtKB) (Swiss-Prot Project Members, 2003.10.10)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mRpL28 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59899 DroID - A comprehensive database of gene and protein interactions. • FBgn0031660 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33715
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23657 Dere\GG25036 Dgri\GH10245 Dmoj\GI15386 Dper\GL26538 Dpse\GA17686 Dsec\GM18510 Dsim\GD23314 Dvir\GJ17276 Dwil\GK24462 Dyak\GE11277
Curated drosophilid orthologs	Dpse\GA17686
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008601-PA Aedes aegypti (mosquito) AGAP008376-PA Anopheles gambiae (mosquito) XP_395930.3 Apis mellifera (honey bee) XP_001942935.1 Acyrthosiphon pisum (pea aphid) XP_001950716.1 Acyrthosiphon pisum (pea aphid) 235683 Branchiostoma floridae (lancelet) BGIBMGA001252-PA Bombyx mori (silk worm) ENSBTAP00000022057 Bos taurus (bovine) CN16375 Caenorhabditis brenneri (small nematode) CBP15802 Caenorhabditis briggsae (nematode) CE19599 Caenorhabditis elegans (worm) ENSCAFP00000029123 Canis familiaris (dog) CAGL0K10912g Candida glabrata (haploid yeast) JA03782 Caenorhabditis japonica (nematode) CPIJ001738 Culex pipens (mosquito) ENSCPOP00000006472 Cavia porcellus (guinea pig) RP14725 Caenorhabditis remanei (nematode) ENSCSAVP00000006282 Ciona savignyi (sedentary tunicate) 171915 Capitella spl (polychaete worm) 94742 Daphnia pulex (daphnia) ENSDARP00000075223 Danio rerio (zebra fish) ENSECAP00000020166 Equus caballus (horse) ENSGACP00000012734 Gymnopilus aculeatus (mushroom) ENSGALP00000012068 Gallus gallus (chicken) 155963 Hypsipyla robusta (cedar shoot borer) ENSP00000380843 Homo sapiens (human) ISCW010492-PA Ixodes scapularis (deer tick) 224221 Lottia gigantea (owl limpet) ENSMODP00000020801 Monodelphis domestica (gray opossum) ENSMMUP00000000820 Macaca mulatta (rhesus monkey) ENSMUSP00000025014 Mus musculus (house mouse) XP_001604861.1 Nasonia vitripennis (wasp) ENSOANP00000022340 Ornithorynchus anatinus (platypus) ENSORLP00000008551 Oryzias latipes (japanese killifish) PHUM005422-PA Pediculus humanus (human body louse) ENSPPYP00000007820 Pongo pygmaeus (orangutan) ENSPTRP00000012873 Pan troglodytes (chimpanzee) Smp_181290 Schistosoma mansoni (trematode parasite) XP_001195540.1 Strongylocentrotus purpuratus (purple sea urchin) ENSTNIP00000010564 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000028672 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000025304 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15604 LH24011 ISCW010492 FBgn0229095 FBgn0226422 FBgn0204452 FBgn0194700 FBgn0173417 JGI_V11_94742 FBgn0077696 FBgn0164120 FBgn0138135 FBgn0117726 FBgn0117165 FBgn0100651 CPIJ001738 CPIJ019950 BGIBMGA001252 ACYPI007188 ACYPI002074 GB14554 AGAP008376 AAEL008601 PB25088 PHUM050870 GLEAN_08271
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	27188 y1 w*; P{EP}mRpL28G5801 30714 y1 w*; Mi{MIC}mRpL28MI00357/CyO
VDRC	v105628 P{KK100905}VIE-260B v41949 w1118; P{GD11073}v41949 v41950 w1118; P{GD11073}v41950 v46374 w1118; P{GD11073}v46374
Genomic Clones ( 2 )
	BACR13M11 BACR40I04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 95 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE47667
Other clones	IP19992
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03416 GH03559 GH06376 GH07827 GH19654 GM01468 GM03727 GM30080 LD17562 LD18883 LD28052 LD29045 LD29059 LD33639 RE14078 RE20726 RE20867 RE43376 RH58854
Other clones	bs60e08 Dmel_dig_001763_0684_3665 EK057326 EK157062 EK199034 ESG015c.E21.1_G08 GM01878 RP003006349 RP003010952 RP003015749 RP003045361 RP003070186 RP003071954 RP003080195 RP003090071 RP003104158 RP003106597 RP003122114 RP003127299 RP003133614 RP003134684 RP003135884 RP003162557 RP003163264 RP003170335 RP003171983 RP003202835 RP003205272 RP003208683 RP003219500 RP003223380 RP003247838 RP003257112 RP003267794 RP003269295 RP003272542 RP003279517 RP003302312 RP003310833 RP003331323 RP003332814 RP003336898 RP003340961 RP003342657 RP003345589 RP003351701 RP003359256 RP003363883 RP003372476 RP003385436 RP003386962 RP003387644 RP003400947 RP003416110 RP003416543 RP003425141 RP003454814 RP003484596 RP003512742 RP003524543 RP003528374 RP003557676 RP003564735 RP003615118 RP003623743 RP003629734 RP003648084 RP003656050 RP003659888 RP003665656 RP003668170 RP003675290 RP003675950 UUGC0890
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33715
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135043 RefSeq (Proteins) • NP_608887 DDBJ / EMBL / GenBank • AAF52188 AAF52188.1 AAL68304 AI107084 AY075494 BI362970 Entrez Gene - A searchable database of RefSeq genes. • 33715 UniProtKB/Swiss-Prot • Q9VMX0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Exoribonuclease, phosphorolytic domain 1 (IPR001247)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59899 DroID - A comprehensive database of gene and protein interactions. • FBgn0031660 DRSC - Results from RNAi screens. • FBgn0031660 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3782-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33715 InParanoid A subset of ortholog calls from InParanoid. • AAEL008601-PA Aedes aegypti (mosquito) AGAP008376-PA Anopheles gambiae (mosquito) XP_395930.3 Apis mellifera (honey bee) XP_001942935.1 Acyrthosiphon pisum (pea aphid) XP_001950716.1 Acyrthosiphon pisum (pea aphid) 235683 Branchiostoma floridae (lancelet) BGIBMGA001252-PA Bombyx mori (silk worm) ENSBTAP00000022057 Bos taurus (bovine) CN16375 Caenorhabditis brenneri (small nematode) CBP15802 Caenorhabditis briggsae (nematode) CE19599 Caenorhabditis elegans (worm) ENSCAFP00000029123 Canis familiaris (dog) CAGL0K10912g Candida glabrata (haploid yeast) JA03782 Caenorhabditis japonica (nematode) CPIJ001738 Culex pipens (mosquito) ENSCPOP00000006472 Cavia porcellus (guinea pig) RP14725 Caenorhabditis remanei (nematode) ENSCSAVP00000006282 Ciona savignyi (sedentary tunicate) 171915 Capitella spl (polychaete worm) 94742 Daphnia pulex (daphnia) ENSDARP00000075223 Danio rerio (zebra fish) ENSECAP00000020166 Equus caballus (horse) ENSGACP00000012734 Gymnopilus aculeatus (mushroom) ENSGALP00000012068 Gallus gallus (chicken) 155963 Hypsipyla robusta (cedar shoot borer) ENSP00000380843 Homo sapiens (human) ISCW010492-PA Ixodes scapularis (deer tick) 224221 Lottia gigantea (owl limpet) ENSMODP00000020801 Monodelphis domestica (gray opossum) ENSMMUP00000000820 Macaca mulatta (rhesus monkey) ENSMUSP00000025014 Mus musculus (house mouse) XP_001604861.1 Nasonia vitripennis (wasp) ENSOANP00000022340 Ornithorynchus anatinus (platypus) ENSORLP00000008551 Oryzias latipes (japanese killifish) PHUM005422-PA Pediculus humanus (human body louse) ENSPPYP00000007820 Pongo pygmaeus (orangutan) ENSPTRP00000012873 Pan troglodytes (chimpanzee) Smp_181290 Schistosoma mansoni (trematode parasite) XP_001195540.1 Strongylocentrotus purpuratus (purple sea urchin) ENSTNIP00000010564 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000028672 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000025304 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33715 modMine - Data generated by the modENCODE project. • FBgn0031660 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15604 LH24011 ISCW010492 FBgn0229095 FBgn0226422 FBgn0204452 FBgn0194700 FBgn0173417 JGI_V11_94742 FBgn0077696 FBgn0164120 FBgn0138135 FBgn0117726 FBgn0117165 FBgn0100651 CPIJ001738 CPIJ019950 BGIBMGA001252 ACYPI007188 ACYPI002074 GB14554 AGAP008376 AAEL008601 PB25088 PHUM050870 GLEAN_08271
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG3782 (Pile et al., 2003, Roos et al., 2002, Keleman et al., 2009.8.5, Marygold et al., 2007) MRP-L28 (Koc et al., 2001) mRpL28 (Marygold et al., 2007)
Name Synonym	ecdysteroid regulated 16kd protein (Zou et al., 2000) mitochondrial ribosomal protein L28 (Koc et al., 2001)
Secondary FlyBase IDs
References ( 20 )
Research paper	Casad et al., 2011, Genetics 189(3): 861--870 Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency in Drosophila melanogaster. [FBrf0216591] Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Pile et al., 2003, J. Biol. Chem. 278(39): 37840--37848 The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: Implications for the regulation of energy metabolism. [FBrf0162185] Koc et al., 2001, J. Biol. Chem. 276(47): 43958--43969 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. [FBrf0145610] Zou et al., 2000, Proc. Natl. Acad. Sci. USA 97(25): 13726--13731 Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. [FBrf0131436]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Roos et al., 2002, J. Biol. Chem. 277(5): 3168--3175 Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. [FBrf0144936]
Personal communication to FlyBase	Bellen, 2010.3.31, BDGP_2010_0401.GDP.xml BDGP_2010_0401.GDP.xml [FBrf0210427] Bellen, 2009.4.8, BDGP_2009_0408.GenExel.xml BDGP_2009_0408.GenExel.xml [FBrf0207636] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Protein sequence record	Swiss-Prot Project Members, 2003.10.10, UniProtKB: Q9VMX0 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28). [FBrf0172717]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]