General Information Symbol Dmel\ CG3887Species D. melanogaster Name Annotation symbol CG3887 Feature type protein_coding_gene FlyBase ID FBgn0031670 Gene Model Status Current Stock availability 1 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 25C1-25C1 Sequence location 2L:5,010,922..5,012,127 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG3887 (FBgn0031670). It is a protein_coding_gene from
Drosophila melanogaster . An electronic pipeline based on InterPro domains suggests that it has the
molecular function : selenium binding. An electronic pipeline based on InterPro domains suggests that it is involved in the
biological process : cell redox homeostasis.
4 alleles are reported . No phenotypic data is available. It has
3 annotated transcripts and
3 annotated polypeptides .
Protein features are: Selenoprotein T; Selenoprotein, Rdx type; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop. Comments on Affy2 ProbeSet: ProbeSet 1624032_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3887. Gene sequence location is
2L:5010922..5012127 .
User Contributed Data
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FB2013_03
FB2013_02
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
1349.2
Larval Fat Body
1199.9
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
1196.05
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(572.15)
Larval Midgut
(616.6)
Larval Hindgut
(659.6)
Larval Malpighian Tubules
(1349.2)
Larval Fat Body
(1199.9)
Larval Salivary Gland
(822.1)
Larval Trachea
(814.075)
Larval Carcass
(677.6)
Adult Head
(660.8)
Adult Eye
(1196.05)
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
(610)
Adult Crop
468.8
Adult Midgut
(796.3)
Adult Hindgut
(593.6)
Adult Malpighian Tubules
(671.6)
Adult Fat Body
(656.5)
Adult Salivary Gland
(594.9)
Adult Heart
(1016.45)
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
(779.7)
Adult Testis
(718.1)
Adult Male Accessory Gland
(791.8)
Adult Carcass
(769.4)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
(1349.2)
Larval Fat Body
(1199.9)
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
(1196.05)
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
1349.2
Larval Fat Body
1199.9
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
1196.05
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
1349.2
Larval Fat Body
1199.9
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
1196.05
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
(1349.2)
Larval Fat Body
(1199.9)
Larval Salivary Gland
(822.1)
Larval Trachea
(814.075)
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
(1196.05)
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
(1016.45)
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
1349.2
Larval Fat Body
1199.9
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
1196.05
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
572.15
Larval Midgut
616.6
Larval Hindgut
659.6
Larval Malpighian Tubules
1349.2
Larval Fat Body
1199.9
Larval Salivary Gland
822.1
Larval Trachea
814.075
Larval Carcass
677.6
Adult Head
660.8
Adult Eye
1196.05
Adult Brain
515
Adult Thoracic-Abdominal Ganglion
610
Adult Crop
468.8
Adult Midgut
796.3
Adult Hindgut
593.6
Adult Malpighian Tubules
671.6
Adult Fat Body
656.5
Adult Salivary Gland
594.9
Adult Heart
1016.45
Adult VirginFemale Spermatheca
521.2
Adult InseminatedFemale Spermatheca
512.9
Adult Ovary
779.7
Adult Testis
718.1
Adult Male Accessory Gland
791.8
Adult Carcass
769.4
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
660.8
NA
Eye
1196.05
NA
Brain
515
572.15
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
610
NA
Crop
468.8
616.6
Midgut
796.3
659.6
Hindgut
593.6
1349.2
Malpighian Tubules
671.6
1199.9
Fat Body
656.5
822.1
Salivary Gland
594.9
NA
Heart
1016.45
814.075
Trachea
NA
NA
VirginFemale Spermatheca
521.2
NA
InseminatedFemale Spermatheca
512.9
NA
Ovary
779.7
NA
Testis
718.1
NA
Male Accessory Gland
791.8
677.6
Carcass
769.4
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
114
head, mated 20-day male
148
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
120
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
150
ovary, mated 4-day female
121
testis, mated 4-day male
405
accessory gland, mated 4-day male
102
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(105)
central nervous system, larvae L3
(98)
central nervous system, pupae P8
(74)
head, virgin 1-day female
(56)
head, virgin 4-day female
(53)
head, virgin 20-day female
(45)
head, mated 1-day female
(48)
head, mated 4-day female
(66)
head, mated 20-day female
(45)
head, mated 1-day male
(59)
head, mated 4-day male
(114)
head, mated 20-day male
(148)
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
(44)
digestive system, larvae L3 wandering
(87)
digestive system, 1-day adult
(91)
digestive system, 4-day adult
(87)
digestive system, 20-day adult
(62)
fat body, larvae L3 wandering
(53)
fat body, white prepupae
(120)
fat body, pupae P8
(74)
carcass, larvae L3 wandering
(87)
carcass, 1-day adult
(51)
carcass, 4-day adult
(64)
carcass, 20-day adult
(44)
ovary, virgin 4-day female
(150)
ovary, mated 4-day female
(121)
testis, mated 4-day male
(405)
accessory gland, mated 4-day male
(102)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
(114)
head, mated 20-day male
(148)
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
(120)
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
(150)
ovary, mated 4-day female
(121)
testis, mated 4-day male
(405)
accessory gland, mated 4-day male
102
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
114
head, mated 20-day male
148
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
120
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
150
ovary, mated 4-day female
121
testis, mated 4-day male
405
accessory gland, mated 4-day male
102
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
114
head, mated 20-day male
148
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
120
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
150
ovary, mated 4-day female
121
testis, mated 4-day male
405
accessory gland, mated 4-day male
102
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(105)
central nervous system, larvae L3
(98)
central nervous system, pupae P8
(74)
head, virgin 1-day female
(56)
head, virgin 4-day female
(53)
head, virgin 20-day female
(45)
head, mated 1-day female
(48)
head, mated 4-day female
(66)
head, mated 20-day female
(45)
head, mated 1-day male
(59)
head, mated 4-day male
(114)
head, mated 20-day male
(148)
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
(44)
digestive system, larvae L3 wandering
(87)
digestive system, 1-day adult
(91)
digestive system, 4-day adult
(87)
digestive system, 20-day adult
(62)
fat body, larvae L3 wandering
(53)
fat body, white prepupae
(120)
fat body, pupae P8
(74)
carcass, larvae L3 wandering
(87)
carcass, 1-day adult
(51)
carcass, 4-day adult
(64)
carcass, 20-day adult
(44)
ovary, virgin 4-day female
(150)
ovary, mated 4-day female
(121)
testis, mated 4-day male
(405)
accessory gland, mated 4-day male
(102)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
114
head, mated 20-day male
(148)
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
120
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
(150)
ovary, mated 4-day female
121
testis, mated 4-day male
(405)
accessory gland, mated 4-day male
102
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
98
central nervous system, pupae P8
74
head, virgin 1-day female
56
head, virgin 4-day female
53
head, virgin 20-day female
45
head, mated 1-day female
48
head, mated 4-day female
66
head, mated 20-day female
45
head, mated 1-day male
59
head, mated 4-day male
114
head, mated 20-day male
148
salivary gland, larvae L3 wandering
25
salivary gland, white prepupae
44
digestive system, larvae L3 wandering
87
digestive system, 1-day adult
91
digestive system, 4-day adult
87
digestive system, 20-day adult
62
fat body, larvae L3 wandering
53
fat body, white prepupae
120
fat body, pupae P8
74
carcass, larvae L3 wandering
87
carcass, 1-day adult
51
carcass, 4-day adult
64
carcass, 20-day adult
44
ovary, virgin 4-day female
150
ovary, mated 4-day female
121
testis, mated 4-day male
405
accessory gland, mated 4-day male
102
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
111
embryo 02-04hr
163
embryo 04-06hr
187
embryo 06-08hr
119
embryo 08-10hr
135
embryo 10-12hr
160
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
110
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(111)
embryo 02-04hr
(163)
embryo 04-06hr
(187)
embryo 06-08hr
(119)
embryo 08-10hr
(135)
embryo 10-12hr
(160)
embryo 12-14hr
(105)
embryo 14-16hr
(88)
embryo 16-18hr
(77)
embryo 18-20hr
(47)
embryo 20-22hr
(36)
embryo 22-24hr
(47)
larva L1
(54)
larva L2
(74)
larva L3 12hr old
(61)
larva L3 puffstage 1-2
(69)
larva L3 puffstage 3-6
(73)
larva L3 puffstage 7-9
(106)
white prepupae new
(110)
white prepupae 12hr
(80)
white prepupae 24hr
(93)
pupae 2d postWPP
(79)
pupae 3d postWPP
(57)
pupae 4d postWPP
(46)
adult male 01day
(53)
adult male 05day
(68)
adult male 30day
(69)
adult female 01day
(57)
adult female 05day
(72)
adult female 30day
(73)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(111)
embryo 02-04hr
(163)
embryo 04-06hr
(187)
embryo 06-08hr
(119)
embryo 08-10hr
(135)
embryo 10-12hr
(160)
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
(110)
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
111
embryo 02-04hr
163
embryo 04-06hr
187
embryo 06-08hr
119
embryo 08-10hr
135
embryo 10-12hr
160
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
110
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
111
embryo 02-04hr
163
embryo 04-06hr
187
embryo 06-08hr
119
embryo 08-10hr
135
embryo 10-12hr
160
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
110
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(111)
embryo 02-04hr
(163)
embryo 04-06hr
(187)
embryo 06-08hr
(119)
embryo 08-10hr
(135)
embryo 10-12hr
(160)
embryo 12-14hr
(105)
embryo 14-16hr
(88)
embryo 16-18hr
(77)
embryo 18-20hr
(47)
embryo 20-22hr
(36)
embryo 22-24hr
(47)
larva L1
(54)
larva L2
(74)
larva L3 12hr old
(61)
larva L3 puffstage 1-2
(69)
larva L3 puffstage 3-6
(73)
larva L3 puffstage 7-9
(106)
white prepupae new
(110)
white prepupae 12hr
(80)
white prepupae 24hr
(93)
pupae 2d postWPP
(79)
pupae 3d postWPP
(57)
pupae 4d postWPP
(46)
adult male 01day
(53)
adult male 05day
(68)
adult male 30day
(69)
adult female 01day
(57)
adult female 05day
(72)
adult female 30day
(73)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
111
embryo 02-04hr
(163)
embryo 04-06hr
(187)
embryo 06-08hr
119
embryo 08-10hr
135
embryo 10-12hr
(160)
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
110
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
111
embryo 02-04hr
163
embryo 04-06hr
187
embryo 06-08hr
119
embryo 08-10hr
135
embryo 10-12hr
160
embryo 12-14hr
105
embryo 14-16hr
88
embryo 16-18hr
77
embryo 18-20hr
47
embryo 20-22hr
36
embryo 22-24hr
47
larva L1
54
larva L2
74
larva L3 12hr old
61
larva L3 puffstage 1-2
69
larva L3 puffstage 3-6
73
larva L3 puffstage 7-9
106
white prepupae new
110
white prepupae 12hr
80
white prepupae 24hr
93
pupae 2d postWPP
79
pupae 3d postWPP
57
pupae 4d postWPP
46
adult male 01day
53
adult male 05day
68
adult male 30day
69
adult female 01day
57
adult female 05day
72
adult female 30day
73
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
406
Schneider line 2 Sg4
201
embryonic 1182-4H
123
embryonic GM2
89
embryonic Kc167
182
embryonic S1
139
embryonic S3
142
leg disc CME L1
153
wing disc CME-W2
311
wing disc ML-DmD8
122
wing disc ML-DmD9
153
wing disc ML-DmD16-c3
115
wing disc ML-DmD21
391
wing disc ML-DmD32
189
haltere disc ML-DmD17-c3
136
eye-antennal disc ML-DmD11
138
antennal disc ML-DmD20-c5
212
mixed discs ML-DmD4-c1
177
CNS ML-DmBG1-c1
290
CNS ML-DmBG2-c2
220
tumorous blood cells mbn2
187
ovary fGS/OSS
91
ovary OSC
274
ovary OSS
75
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(406)
Schneider line 2 Sg4
(201)
embryonic 1182-4H
(123)
embryonic GM2
(89)
embryonic Kc167
(182)
embryonic S1
(139)
embryonic S3
(142)
leg disc CME L1
(153)
wing disc CME-W2
(311)
wing disc ML-DmD8
(122)
wing disc ML-DmD9
(153)
wing disc ML-DmD16-c3
(115)
wing disc ML-DmD21
(391)
wing disc ML-DmD32
(189)
haltere disc ML-DmD17-c3
(136)
eye-antennal disc ML-DmD11
(138)
antennal disc ML-DmD20-c5
(212)
mixed discs ML-DmD4-c1
(177)
CNS ML-DmBG1-c1
(290)
CNS ML-DmBG2-c2
(220)
tumorous blood cells mbn2
(187)
ovary fGS/OSS
(91)
ovary OSC
(274)
ovary OSS
(75)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(406)
Schneider line 2 Sg4
(201)
embryonic 1182-4H
(123)
embryonic GM2
89
embryonic Kc167
(182)
embryonic S1
(139)
embryonic S3
(142)
leg disc CME L1
(153)
wing disc CME-W2
(311)
wing disc ML-DmD8
(122)
wing disc ML-DmD9
(153)
wing disc ML-DmD16-c3
(115)
wing disc ML-DmD21
(391)
wing disc ML-DmD32
(189)
haltere disc ML-DmD17-c3
(136)
eye-antennal disc ML-DmD11
(138)
antennal disc ML-DmD20-c5
(212)
mixed discs ML-DmD4-c1
(177)
CNS ML-DmBG1-c1
(290)
CNS ML-DmBG2-c2
(220)
tumorous blood cells mbn2
(187)
ovary fGS/OSS
91
ovary OSC
(274)
ovary OSS
75
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
406
Schneider line 2 Sg4
201
embryonic 1182-4H
123
embryonic GM2
89
embryonic Kc167
182
embryonic S1
139
embryonic S3
142
leg disc CME L1
153
wing disc CME-W2
311
wing disc ML-DmD8
122
wing disc ML-DmD9
153
wing disc ML-DmD16-c3
115
wing disc ML-DmD21
391
wing disc ML-DmD32
189
haltere disc ML-DmD17-c3
136
eye-antennal disc ML-DmD11
138
antennal disc ML-DmD20-c5
212
mixed discs ML-DmD4-c1
177
CNS ML-DmBG1-c1
290
CNS ML-DmBG2-c2
220
tumorous blood cells mbn2
187
ovary fGS/OSS
91
ovary OSC
274
ovary OSS
75
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
406
Schneider line 2 Sg4
201
embryonic 1182-4H
123
embryonic GM2
89
embryonic Kc167
182
embryonic S1
139
embryonic S3
142
leg disc CME L1
153
wing disc CME-W2
311
wing disc ML-DmD8
122
wing disc ML-DmD9
153
wing disc ML-DmD16-c3
115
wing disc ML-DmD21
391
wing disc ML-DmD32
189
haltere disc ML-DmD17-c3
136
eye-antennal disc ML-DmD11
138
antennal disc ML-DmD20-c5
212
mixed discs ML-DmD4-c1
177
CNS ML-DmBG1-c1
290
CNS ML-DmBG2-c2
220
tumorous blood cells mbn2
187
ovary fGS/OSS
91
ovary OSC
274
ovary OSS
75
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(406)
Schneider line 2 Sg4
(201)
embryonic 1182-4H
(123)
embryonic GM2
(89)
embryonic Kc167
(182)
embryonic S1
(139)
embryonic S3
(142)
leg disc CME L1
(153)
wing disc CME-W2
(311)
wing disc ML-DmD8
(122)
wing disc ML-DmD9
(153)
wing disc ML-DmD16-c3
(115)
wing disc ML-DmD21
(391)
wing disc ML-DmD32
(189)
haltere disc ML-DmD17-c3
(136)
eye-antennal disc ML-DmD11
(138)
antennal disc ML-DmD20-c5
(212)
mixed discs ML-DmD4-c1
(177)
CNS ML-DmBG1-c1
(290)
CNS ML-DmBG2-c2
(220)
tumorous blood cells mbn2
(187)
ovary fGS/OSS
(91)
ovary OSC
(274)
ovary OSS
(75)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(406)
Schneider line 2 Sg4
(201)
embryonic 1182-4H
123
embryonic GM2
89
embryonic Kc167
(182)
embryonic S1
139
embryonic S3
142
leg disc CME L1
(153)
wing disc CME-W2
(311)
wing disc ML-DmD8
122
wing disc ML-DmD9
(153)
wing disc ML-DmD16-c3
115
wing disc ML-DmD21
(391)
wing disc ML-DmD32
(189)
haltere disc ML-DmD17-c3
136
eye-antennal disc ML-DmD11
138
antennal disc ML-DmD20-c5
(212)
mixed discs ML-DmD4-c1
(177)
CNS ML-DmBG1-c1
(290)
CNS ML-DmBG2-c2
(220)
tumorous blood cells mbn2
(187)
ovary fGS/OSS
91
ovary OSC
(274)
ovary OSS
75
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
406
Schneider line 2 Sg4
201
embryonic 1182-4H
123
embryonic GM2
89
embryonic Kc167
182
embryonic S1
139
embryonic S3
142
leg disc CME L1
153
wing disc CME-W2
311
wing disc ML-DmD8
122
wing disc ML-DmD9
153
wing disc ML-DmD16-c3
115
wing disc ML-DmD21
391
wing disc ML-DmD32
189
haltere disc ML-DmD17-c3
136
eye-antennal disc ML-DmD11
138
antennal disc ML-DmD20-c5
212
mixed discs ML-DmD4-c1
177
CNS ML-DmBG1-c1
290
CNS ML-DmBG2-c2
220
tumorous blood cells mbn2
187
ovary fGS/OSS
91
ovary OSC
274
ovary OSS
75
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
186
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(37)
cold shock, 4-day adult
(28)
heat shock, 4-day adult
(70)
Cadmium 50 mM 6 hrs, larvae L3
(85)
Cadmium 50 mM 12 hrs, larvae L3
(106)
Cadmium 50 mM 48 hrs, 4-day adult
(81)
Cadmium 100 mM 48 hrs, 4-day adult
(98)
Copper 0.5 mM 12 hrs, larvae L3
(34)
Copper 15 mM 48 hrs, 4-day adult
(186)
Zinc 5 mM 12 hrs, larvae L3
(36)
Zinc 4.5 mM 48 hrs, 4-day adult
(99)
Ethanol 2.5% 3 hrs, larvae L3
(58)
Ethanol 5% 3 hrs, larvae L3
(83)
Ethanol 10% 3 hrs, larvae L3
(50)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(68)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(85)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(55)
Paraquat 5 mM 48 hrs, 4-day adult
(92)
Paraquat 10 mM 48 hrs, 4-day adult
(75)
Rotenone 2 μg 12 hrs, larvae L3
(67)
Rotenone 8 μg 12 hrs, larvae L3
(47)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
(186)
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
186
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
186
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(37)
cold shock, 4-day adult
28
heat shock, 4-day adult
(70)
Cadmium 50 mM 6 hrs, larvae L3
(85)
Cadmium 50 mM 12 hrs, larvae L3
(106)
Cadmium 50 mM 48 hrs, 4-day adult
(81)
Cadmium 100 mM 48 hrs, 4-day adult
(98)
Copper 0.5 mM 12 hrs, larvae L3
(34)
Copper 15 mM 48 hrs, 4-day adult
(186)
Zinc 5 mM 12 hrs, larvae L3
(36)
Zinc 4.5 mM 48 hrs, 4-day adult
(99)
Ethanol 2.5% 3 hrs, larvae L3
(58)
Ethanol 5% 3 hrs, larvae L3
(83)
Ethanol 10% 3 hrs, larvae L3
(50)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(68)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(85)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(55)
Paraquat 5 mM 48 hrs, 4-day adult
(92)
Paraquat 10 mM 48 hrs, 4-day adult
(75)
Rotenone 2 μg 12 hrs, larvae L3
(67)
Rotenone 8 μg 12 hrs, larvae L3
(47)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
(186)
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
37
cold shock, 4-day adult
28
heat shock, 4-day adult
70
Cadmium 50 mM 6 hrs, larvae L3
85
Cadmium 50 mM 12 hrs, larvae L3
106
Cadmium 50 mM 48 hrs, 4-day adult
81
Cadmium 100 mM 48 hrs, 4-day adult
98
Copper 0.5 mM 12 hrs, larvae L3
34
Copper 15 mM 48 hrs, 4-day adult
186
Zinc 5 mM 12 hrs, larvae L3
36
Zinc 4.5 mM 48 hrs, 4-day adult
99
Ethanol 2.5% 3 hrs, larvae L3
58
Ethanol 5% 3 hrs, larvae L3
83
Ethanol 10% 3 hrs, larvae L3
50
Caffeine 1.5 mg/ml 4 hrs, larvae L3
68
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
85
Caffeine 25 mg/ml 48 hrs, 4-day adult
55
Paraquat 5 mM 48 hrs, 4-day adult
92
Paraquat 10 mM 48 hrs, 4-day adult
75
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
47
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 1 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 2 unique terms )There is no information supporting a
cellular component term for this gene.
(Based on a review of available data before: 2006)
Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (40)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6GF41M )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6PZJGT )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG61VJ0P )
Apis mellifera
Western honey bee
Amel\LOC550992
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG003816
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH17606
Atta cephalotes
Leafcutter ant
Acep\ACEP21457
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO20027
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL19526
Linepithema humile
Argentine ant
Lhum\LH16540
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB24749
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6DNCN3 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6N3CHH )
Caenorhabditis elegans
Nematode
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (10)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 1 )VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 169 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 15 )Supplementary material Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping projectDPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data.Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] FlyBase analysis FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] Stock list Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.RNAi stocks available from NIG-FLY. [FBrf0218457] Website Fisher et al., 2012, BDGP insitu homepageBDGP insitu homepage [FBrf0219073]