General Information Symbol Dmel\ OscillinSpecies D. melanogaster Name Oscillin Annotation symbol CG6957 Feature type protein_coding_gene FlyBase ID FBgn0031717 Gene Model Status Current Stock availability 4 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 25E6-25E6 Sequence location 2L:5,547,086..5,549,614 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Oscillin is referred to in FlyBase by the symbol
Dmel\Oscillin (CG6957, FBgn0031717). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : glucosamine-6-phosphate deaminase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the
biological process : carbohydrate metabolic process; N-acetylglucosamine metabolic process.
6 alleles are reported . No phenotypic data is available. It has
8 annotated transcripts and
8 annotated polypeptides .
Protein features are: Glucosamine-6-phosphate isomerase; Glucosamine-6-phosphate isomerase, conserved site; Glucosamine/galactosamine-6-phosphate isomerase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult Malpighian tubules, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval midgut, larval hindgut, adult heart, adult fat body, larval salivary gland, larval trachea, adult spermathecae, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1628828_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Oscillin. Gene sequence location is
2L:5547086..5549614 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
1112.4
Larval Fat Body
1243.4
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
(1112.4)
Larval Fat Body
(1243.4)
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
(544.3)
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
(1112.4)
Larval Fat Body
(1243.4)
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
1112.4
Larval Fat Body
1243.4
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
1112.4
Larval Fat Body
1243.4
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
(1112.4)
Larval Fat Body
(1243.4)
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
1112.4
Larval Fat Body
1243.4
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
81.05
Larval Midgut
250.4
Larval Hindgut
117.6
Larval Malpighian Tubules
1112.4
Larval Fat Body
1243.4
Larval Salivary Gland
116.6
Larval Trachea
140.5
Larval Carcass
229.825
Adult Head
98.4
Adult Eye
81.875
Adult Brain
94.3
Adult Thoracic-Abdominal Ganglion
82.9
Adult Crop
107.3
Adult Midgut
97.7
Adult Hindgut
65.6
Adult Malpighian Tubules
544.3
Adult Fat Body
147.2
Adult Salivary Gland
16.1
Adult Heart
137.325
Adult VirginFemale Spermatheca
323.2
Adult InseminatedFemale Spermatheca
245.4
Adult Ovary
12.5
Adult Testis
99.5
Adult Male Accessory Gland
7
Adult Carcass
97.1
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
98.4
NA
Eye
81.875
NA
Brain
94.3
81.05
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
82.9
NA
Crop
107.3
250.4
Midgut
97.7
117.6
Hindgut
65.6
1112.4
Malpighian Tubules
544.3
1243.4
Fat Body
147.2
116.6
Salivary Gland
no informative data
NA
Heart
137.325
140.5
Trachea
NA
NA
VirginFemale Spermatheca
323.2
NA
InseminatedFemale Spermatheca
245.4
NA
Ovary
no informative data
NA
Testis
99.5
NA
Male Accessory Gland
7
229.825
Carcass
97.1
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
(48)
salivary gland, white prepupae
(32)
digestive system, larvae L3 wandering
(30)
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
(49)
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
(48)
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
(49)
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
12
central nervous system, larvae L3
7
central nervous system, pupae P8
7
head, virgin 1-day female
5
head, virgin 4-day female
2
head, virgin 20-day female
5
head, mated 1-day female
2
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
48
salivary gland, white prepupae
32
digestive system, larvae L3 wandering
30
digestive system, 1-day adult
9
digestive system, 4-day adult
5
digestive system, 20-day adult
4
fat body, larvae L3 wandering
16
fat body, white prepupae
10
fat body, pupae P8
49
carcass, larvae L3 wandering
22
carcass, 1-day adult
4
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
7
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
(27)
embryo 08-10hr
(53)
embryo 10-12hr
(94)
embryo 12-14hr
(53)
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
(41)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(79)
white prepupae new
(49)
white prepupae 12hr
(95)
white prepupae 24hr
(53)
pupae 2d postWPP
(46)
pupae 3d postWPP
(51)
pupae 4d postWPP
(47)
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
(53)
embryo 10-12hr
(94)
embryo 12-14hr
(53)
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
(41)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(79)
white prepupae new
(49)
white prepupae 12hr
(95)
white prepupae 24hr
(53)
pupae 2d postWPP
(46)
pupae 3d postWPP
(51)
pupae 4d postWPP
(47)
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
6
embryo 04-06hr
19
embryo 06-08hr
27
embryo 08-10hr
53
embryo 10-12hr
94
embryo 12-14hr
53
embryo 14-16hr
14
embryo 16-18hr
8
embryo 18-20hr
5
embryo 20-22hr
6
embryo 22-24hr
10
larva L1
13
larva L2
17
larva L3 12hr old
13
larva L3 puffstage 1-2
41
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
79
white prepupae new
49
white prepupae 12hr
95
white prepupae 24hr
53
pupae 2d postWPP
46
pupae 3d postWPP
51
pupae 4d postWPP
47
adult male 01day
13
adult male 05day
12
adult male 30day
10
adult female 01day
7
adult female 05day
6
adult female 30day
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
8
Schneider line 2 Sg4
3
embryonic 1182-4H
3
embryonic GM2
5
embryonic Kc167
3
embryonic S1
10
embryonic S3
4
leg disc CME L1
2
wing disc CME-W2
0
wing disc ML-DmD8
0
wing disc ML-DmD9
3
wing disc ML-DmD16-c3
2
wing disc ML-DmD21
4
wing disc ML-DmD32
3
haltere disc ML-DmD17-c3
6
eye-antennal disc ML-DmD11
4
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
3
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
3
ovary fGS/OSS
2
ovary OSC
3
ovary OSS
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
(35)
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
(35)
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
5
cold shock, 4-day adult
5
heat shock, 4-day adult
8
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
35
Cadmium 50 mM 48 hrs, 4-day adult
9
Cadmium 100 mM 48 hrs, 4-day adult
4
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
3
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
4
Ethanol 5% 3 hrs, larvae L3
12
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
3
Rotenone 2 μg 12 hrs, larvae L3
23
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function inferred from sequence or structural similarity with
EMBL:AF088903 Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (45)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG64MZC6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6TMR9X )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6SBCTT )
Apis mellifera
Western honey bee
Amel\Oscillin
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG012452
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\nagB
Atta cephalotes
Leafcutter ant
Acep\nagB
Camponotus floridanus
Florida carpenter ant
Cflo\nagB
Harpegnathos saltator
Jerdons jumping ant
Hsal\nagB
Linepithema humile
Argentine ant
Lhum\LH22011
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB16111
Solenopsis invicta
Red fire ant
Sinv\SINV11755
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG60P2PM )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG647TNB )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (2)AAA Orthologs (10)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )Bloomington Harvard VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 190 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: Oscillin CG6957
Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 3 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 21 )Generate a list of List References by type
Recent research papers ( 1 )
Zimek and Weber, 2011, Europ. J. Cell Biol. 90(4): 356--364Flanking genes of an essential gene give information about the evolution of metazoa. [FBrf0213069]