an evolutionarily conserved FERM domain protein containing a protein tyrosine phosphatase (PTP) domain - a binding partner of the upstream Hippo signaling component Kibra - regulates midgut homeostasis
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.44
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pez using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pez in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Pez mutants that lack detectable Pez protein and flies carrying overlapping deletions for Pez are viable. The putative lethal Pez mutants reported in FBrf0146134 were subsequently found to map to Cpr, the adjacent gene, and do not affect Pez.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.