General Information Symbol Dmel\ CG11188Species D. melanogaster Name Annotation symbol CG11188 Feature type protein_coding_gene FlyBase ID FBgn0031851 Gene Model Status Current Stock availability 6 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 27A1-27A1 Sequence location 2L:6,717,625..6,719,389 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG11188 (FBgn0031851). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. There is experimental evidence that it is involved in the
biological process : neurogenesis.
6 alleles are reported . No phenotypic data is available. It has
one annotated transcript and
one annotated polypeptide .
Protein features are: AATF leucine zipper-containing domain; Apoptosis-antagonizing transcription factor, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1624335_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11188. Gene sequence location is
2L:6717625..6719389 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: reported as salivary gland primordium
Comment: reported as muscle system primordium
Comment: reported as muscle system primordium
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
77.05
Larval Midgut
30.1
Larval Hindgut
43.5
Larval Malpighian Tubules
28
Larval Fat Body
22.3
Larval Salivary Gland
52.1
Larval Trachea
68.05
Larval Carcass
59.325
Adult Head
36.4
Adult Eye
35.25
Adult Brain
50.9
Adult Thoracic-Abdominal Ganglion
61.1
Adult Crop
45.1
Adult Midgut
47.8
Adult Hindgut
35.8
Adult Malpighian Tubules
32.7
Adult Fat Body
48.1
Adult Salivary Gland
49.3
Adult Heart
37.85
Adult VirginFemale Spermatheca
27.7
Adult InseminatedFemale Spermatheca
31.8
Adult Ovary
122.1
Adult Testis
32.1
Adult Male Accessory Gland
69
Adult Carcass
43.7
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
36.4
NA
Eye
35.25
NA
Brain
50.9
77.05
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
61.1
NA
Crop
45.1
30.1
Midgut
47.8
43.5
Hindgut
35.8
28
Malpighian Tubules
32.7
no informative data
Fat Body
48.1
52.1
Salivary Gland
49.3
NA
Heart
37.85
68.05
Trachea
NA
NA
VirginFemale Spermatheca
27.7
NA
InseminatedFemale Spermatheca
31.8
NA
Ovary
122.1
NA
Testis
32.1
NA
Male Accessory Gland
69
59.325
Carcass
43.7
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
(37)
ovary, mated 4-day female
(40)
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
(37)
ovary, mated 4-day female
(40)
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
14
central nervous system, larvae L3
13
central nervous system, pupae P8
12
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
4
head, mated 1-day female
5
head, mated 4-day female
9
head, mated 20-day female
3
head, mated 1-day male
6
head, mated 4-day male
6
head, mated 20-day male
6
salivary gland, larvae L3 wandering
0
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
3
digestive system, 4-day adult
7
digestive system, 20-day adult
4
fat body, larvae L3 wandering
1
fat body, white prepupae
4
fat body, pupae P8
0
carcass, larvae L3 wandering
9
carcass, 1-day adult
4
carcass, 4-day adult
9
carcass, 20-day adult
5
ovary, virgin 4-day female
37
ovary, mated 4-day female
40
testis, mated 4-day male
8
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(39)
embryo 02-04hr
(39)
embryo 04-06hr
(35)
embryo 06-08hr
(40)
embryo 08-10hr
(49)
embryo 10-12hr
(43)
embryo 12-14hr
(33)
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
(28)
adult female 30day
(29)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(39)
embryo 02-04hr
(39)
embryo 04-06hr
(35)
embryo 06-08hr
(40)
embryo 08-10hr
(49)
embryo 10-12hr
(43)
embryo 12-14hr
(33)
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
39
embryo 02-04hr
39
embryo 04-06hr
35
embryo 06-08hr
40
embryo 08-10hr
49
embryo 10-12hr
43
embryo 12-14hr
33
embryo 14-16hr
16
embryo 16-18hr
15
embryo 18-20hr
11
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
26
larva L2
17
larva L3 12hr old
11
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
7
larva L3 puffstage 7-9
8
white prepupae new
8
white prepupae 12hr
7
white prepupae 24hr
9
pupae 2d postWPP
9
pupae 3d postWPP
8
pupae 4d postWPP
4
adult male 01day
4
adult male 05day
5
adult male 30day
4
adult female 01day
15
adult female 05day
28
adult female 30day
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
(66)
embryonic S1
(31)
embryonic S3
26
leg disc CME L1
(31)
wing disc CME-W2
(34)
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
(37)
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
(30)
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
(44)
CNS ML-DmBG1-c1
(40)
CNS ML-DmBG2-c2
(53)
tumorous blood cells mbn2
(37)
ovary fGS/OSS
(28)
ovary OSC
(40)
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
(66)
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
(34)
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
(37)
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
(44)
CNS ML-DmBG1-c1
(40)
CNS ML-DmBG2-c2
(53)
tumorous blood cells mbn2
(37)
ovary fGS/OSS
28
ovary OSC
(40)
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
25
embryonic 1182-4H
22
embryonic GM2
20
embryonic Kc167
66
embryonic S1
31
embryonic S3
26
leg disc CME L1
31
wing disc CME-W2
34
wing disc ML-DmD8
23
wing disc ML-DmD9
17
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
24
wing disc ML-DmD32
15
haltere disc ML-DmD17-c3
22
eye-antennal disc ML-DmD11
30
antennal disc ML-DmD20-c5
21
mixed discs ML-DmD4-c1
44
CNS ML-DmBG1-c1
40
CNS ML-DmBG2-c2
53
tumorous blood cells mbn2
37
ovary fGS/OSS
28
ovary OSC
40
ovary OSS
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
(36)
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
(28)
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(29)
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
(33)
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
(36)
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
(33)
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
9
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
5
Cadmium 50 mM 12 hrs, larvae L3
5
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
36
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
3
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
4
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
29
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
20
Paraquat 10 mM 48 hrs, 4-day adult
33
Rotenone 2 μg 12 hrs, larvae L3
8
Rotenone 8 μg 12 hrs, larvae L3
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
insertion of enhancer trap
Gene Ontology: Function, Process
& Cellular Component ( 2 unique terms )There is no information supporting a
molecular function term for this gene.
(Based on a review of available data before: 2006)
Terms Based on
Experimental Evidence ( 1 term ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 1 term ) Molecular Function ( 0 terms) Biological Process ( 0 terms) Cellular Component inferred from sequence or structural similarity with
UniProtKB:Q9NY61
(assigned by UniProtKB)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (46)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6MSDJ6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG679FGX )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6RXWW0 )
Apis mellifera
Western honey bee
Amel\GB53195
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013044
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH26284
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH26285
Atta cephalotes
Leafcutter ant
Acep\ACEP11529
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO21380
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL22897
Linepithema humile
Argentine ant
Lhum\LH17015
Linepithema humile
Argentine ant
Lhum\LH20759
Linepithema humile
Argentine ant
Lhum\LH17018
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB19284
Solenopsis invicta
Red fire ant
Sinv\SINV24680
Solenopsis invicta
Red fire ant
Sinv\SINV11546
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG61ZCSM )
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG62RS26 )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 6 )Bloomington Harvard Kyoto VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 26 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Source for merge of: CG11188 anon-WO0118547.190
Additional comments Source for merge of CG11188 anon-WO0118547.190 was sequence comparison (date:051113).
Other Comments Area matching Drosophila EST AA950741.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym CG11188
(
UniProtKB Project Members, 2005.7.19 ,
Izutsu et al., 2012 ,
Grieder et al., 2007 ,
Grönke et al., 2007 ,
Bharucha et al., 2008 ,
Keleman et al., 2009.8.5 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Secondary FlyBase
IDs References ( 27 )Generate a list of List References by type
Recent research papers ( 2 )
Izutsu et al., 2012, PLoS ONE 7(3): e33288Genome features of "dark-fly", a Drosophila line reared long-term in a dark environment. [FBrf0217825] Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342]