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Gene Dmel\CG11188

General Information
Symbol	Dmel\CG11188	Species	D. melanogaster
Name		Annotation symbol	CG11188
Feature type	protein_coding_gene	FlyBase ID	FBgn0031851
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	27A1-27A1	Sequence location	2L:6,717,627..6,719,389 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11188 (FBgn0031851). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neurogenesis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: TRAUB. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1624335_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11188. Gene sequence location is 2L:6717627..6719389.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN45245 BKN20549 HFA02131
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 27A1-27A1   Limits computationally determined from genome sequence between P{EP}Sec61αEP2180 and P{lacW}Ate1k10809
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11188 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11188-RA FBtr0079299  NM_135222   1701   488
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11188-PA   FBpp0078929   56.0   488   4.48     NP_609066   AAF52427
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • TRAUB (IPR012617)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202384   AA941414   AA950741   AA952144   AE014134 AAF52427   AI239183   AI514933   AX094066   AY071275 AAL48897   BF488506   BG632926   BI234907   BI374643   BI573290   BI573854   CK604687   CK604688   CL943549   CO301267   CO303630   CO303637   CO323312   CO327991   CZ480827   EC065587   EC065588   EC074568   EC087055   EC089447   EC203063   EC215099   EC234693   EV600721   GH738994   GH739787   GH764249   GH766584   GH767165   GH767189
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VM95
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0031851    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0031851 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0031851 expression level Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2988) embryo 02-04hr  (3003) embryo 04-06hr  (2699) embryo 06-08hr  (3015) embryo 08-10hr  (3693) embryo 10-12hr  (3282) embryo 12-14hr  (2521) embryo 14-16hr  (1198) embryo 16-18hr  (1120) embryo 18-20hr  (833) embryo 20-22hr  (1586) embryo 22-24hr  (1626) larva L1  (1952) larva L2  (1328) larva L3 12hr old  (857) larva L3 puffstage 1-2  (451) larva L3 puffstage 3-6  (508) larva L3 puffstage 7-9  (590) white prepupae new  (605) white prepupae 12hr  (566) white prepupae 24hr  (717) pupae 2d postWPP  (704) pupae 3d postWPP  (584) pupae 4d postWPP  (285) adult male 01day  (321) adult male 05day  (379) adult male 30day  (337) adult female 01day  (1110) adult female 05day  (2124) adult female 30day  (2236) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2988) embryo 02-04hr  (3003) embryo 04-06hr  (2699) embryo 06-08hr  (3015) embryo 08-10hr  (3693) embryo 10-12hr  (3282) embryo 12-14hr  (2521) embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr  (1586) embryo 22-24hr  (1626) larva L1  (1952) larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day  (2124) adult female 30day  (2236) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0031851 expression level Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2988) embryo 02-04hr  (3003) embryo 04-06hr  (2699) embryo 06-08hr  (3015) embryo 08-10hr  (3693) embryo 10-12hr  (3282) embryo 12-14hr  (2521) embryo 14-16hr  (1198) embryo 16-18hr  (1120) embryo 18-20hr  (833) embryo 20-22hr  (1586) embryo 22-24hr  (1626) larva L1  (1952) larva L2  (1328) larva L3 12hr old  (857) larva L3 puffstage 1-2  (451) larva L3 puffstage 3-6  (508) larva L3 puffstage 7-9  (590) white prepupae new  (605) white prepupae 12hr  (566) white prepupae 24hr  (717) pupae 2d postWPP  (704) pupae 3d postWPP  (584) pupae 4d postWPP  (285) adult male 01day  (321) adult male 05day  (379) adult male 30day  (337) adult female 01day  (1110) adult female 05day  (2124) adult female 30day  (2236) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2988) embryo 02-04hr  (3003) embryo 04-06hr  (2699) embryo 06-08hr  (3015) embryo 08-10hr  (3693) embryo 10-12hr  (3282) embryo 12-14hr  (2521) embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr  1586 embryo 22-24hr  1626 larva L1  1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day  2124 adult female 30day  2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2988 embryo 02-04hr    3003 embryo 04-06hr    2699 embryo 06-08hr    3015 embryo 08-10hr    3693 embryo 10-12hr    3282 embryo 12-14hr    2521 embryo 14-16hr    1198 embryo 16-18hr    1120 embryo 18-20hr    833 embryo 20-22hr    1586 embryo 22-24hr    1626 larva L1    1952 larva L2    1328 larva L3 12hr old    857 larva L3 puffstage 1-2    451 larva L3 puffstage 3-6    508 larva L3 puffstage 7-9    590 white prepupae new    605 white prepupae 12hr    566 white prepupae 24hr    717 pupae 2d postWPP    704 pupae 3d postWPP    584 pupae 4d postWPP    285 adult male 01day    321 adult male 05day    379 adult male 30day    337 adult female 01day    1110 adult female 05day    2124 adult female 30day    2236 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0031851    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0031851 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0031851 expression level Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0031851 expression level Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    77.05 Larval Midgut    30.1 Larval Hindgut    43.5 Larval Malpighian Tubules    28 Larval Fat Body no informative data Larval Salivary Gland    52.1 Larval Trachea    68.05 Larval Carcass    59.325 Adult Head    36.4 Adult Eye    35.25 Adult Brain    50.9 Adult Thoracic-Abdominal Ganglion    61.1 Adult Crop    45.1 Adult Midgut    47.8 Adult Hindgut    35.8 Adult Malpighian Tubules    32.7 Adult Fat Body    48.1 Adult Salivary Gland    49.3 Adult Heart    37.85 Adult VirginFemale Spermatheca    27.7 Adult InseminatedFemale Spermatheca    31.8 Adult Ovary    122.1 Adult Testis    32.1 Adult Male Accessory Gland    69 Adult Carcass    43.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    36.4   NA  Eye    35.25   NA  Brain    50.9   77.05  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    61.1   NA  Crop    45.1   30.1  Midgut    47.8   43.5  Hindgut    35.8   28  Malpighian Tubules    32.7   no informative data  Fat Body    48.1   52.1  Salivary Gland    49.3   NA  Heart    37.85   68.05  Trachea    NA   NA  VirginFemale Spermatheca    27.7   NA  InseminatedFemale Spermatheca    31.8   NA  Ovary    122.1   NA  Testis    32.1   NA  Male Accessory Gland    69   59.325  Carcass    43.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031851 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11188-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG11188 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 CG11188GD7229 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG11188GD7229 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 CG11188GD7229 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage, with Scer\GAL41407 CG11188GD7229 ganglion mother cell | larval stage, with Scer\GAL41407 CG11188GD7229
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG11188 Class Mutagen Stocks Known lesion CG11188e03057 piggyBac transposase 2 -- CG11188EY13022 P-element activity 2 -- CG11188A1332 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11188 Class Mutagen Stocks Known lesion CG11188GD7229 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11188KK100453 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7027 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7229} NA P{KK100453} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG11188EY13022 NA P{Mae-UAS.6.11}B0583B0583 NA P{Mae-UAS.6.11}B1267B1267 NA P{Mae-UAS.6.11}CG11188A1332 NA miscellaneous insertions PBac{RB}CG11188e03057 NA insertion of enhancer trap P{lacW}l(2)SH1207SH1207 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:Q9NY61 (assigned by UniProtKB) (FBrf0198845)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11188 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60096 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031851 DroID - A comprehensive database of gene and protein interactions. • FBgn0031851 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33943
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14948 Dere\GG10429 Dgri\GH10706 Dmoj\GI11279 Dper\GL25784 Dpse\GA25444 Dsec\GM16208 Dsim\GD23427 Dvir\GJ12452 Dwil\GK24803 Dyak\GE14077
Curated drosophilid orthologs	Dpse\GA10825
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010885-PA Aedes aegypti (mosquito) AGAP007394-PA Anopheles gambiae (mosquito) XP_001122396.1 Apis mellifera (honey bee) At5g61330.1 Arabidopsis thaliana (wall cress) 86940 Batrachochytrium dendrobatidis (chytrid fungus) 106840 Branchiostoma floridae (lancelet) BGIBMGA002766-PA Bombyx mori (silk worm) ENSBTAP00000029234 Bos taurus (bovine) CAL0000848 Candida albicans (a form of yeast) CE32277 Caenorhabditis elegans (worm) ENSCAFP00000026373 Canis familiaris (dog) CAGL0H01419g Candida glabrata (haploid yeast) cn08146 Cryptococcus neoformans (yeast-like fungus) CPIJ005946 Culex pipens (mosquito) ENSCPOP00000005450 Cavia porcellus (guinea pig) 143724 Chlamidomonas reinhardtii (green alga) RP27729 Caenorhabditis remanei (nematode) ENSCSAVP00000006771 Ciona savignyi (sedentary tunicate) 110234 Capitella spl (polychaete worm) DEHA2A14212g Debaryomyces Hansenii (yeast) 308721 Daphnia pulex (daphnia) ENSDARP00000031013 Danio rerio (zebra fish) ENSECAP00000006639 Equus caballus (horse) XP_648572 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005092 Gymnopilus aculeatus (mushroom) ENSGALP00000038336 Gallus gallus (chicken) ENSP00000225402 Homo sapiens (human) ISCW007430-PA Ixodes scapularis (deer tick) KLLA0C10362g Kluyveromyces lactis (yeast) 138224 Lottia gigantea (owl limpet) LmjF20.0920 Leishmania major (virus) 31164 Monocosta brevicollis (choanoflagellate) ENSMODP00000004006 Monodelphis domestica (gray opossum) ENSMMUP00000028534 Macaca mulatta (rhesus monkey) ENSMUSP00000018841 Mus musculus (house mouse) 168185 Nematostella vectensis (starlet anemone) XP_001599692.1 Nasonia vitripennis (wasp) ENSOANP00000018241 Ornithorynchus anatinus (platypus) ENSORLP00000017094 Oryzias latipes (japanese killifish) LOC_Os01g34200.1 Oryza sativa (asian rice) PHUM006123-PA Pediculus humanus (human body louse) PP17506 Pristionchus pacificus (nematode) 89684 Physcomitrella patens (moss) ENSPPYP00000009232 Pongo pygmaeus (orangutan) 75491 Phytophthora ramorum (sudden oak death pathogen) 141125 Phytophthora sojae (root rot pathogen) 249733 Populus trichocarpa (black cottonwood) ENSPTRP00000015430 Pan troglodytes (chimpanzee) ENSRNOP00000000258 Rattus norvegicus (norway rat) 5035481 Sorghum bicolor (sorghum) YDR299W Saccharomyces cerevisiae (budding yeast) SPAC664.08c Schizosaccharomyces pombe (fission yeast) XP_001179690.1 Strongylocentrotus purpuratus (purple sea urchin) 59502 Trichoplax adhaerens (metazoa) XP_966656.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020295 Tetraodon nigroviridis (green spotted pufferfish) 24977 Thalassiosira pseudonana (marine diatom) ENSTRUP00000000315 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000019629 Xenopus tropicalis (frog) YALI0D11462g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB19284 NV16061 LH17018 LH17015 LH20759 ISCW007430 ISCW007431 FBgn0231703 FBgn0226762 FBgn0199694 FBgn0194810 FBgn0171124 JGI_V11_308721 FBgn0246822 FBgn0163368 FBgn0134040 FBgn0118187 FBgn0102738 FBgn0091973 CPIJ005946 BGIBMGA002766 GB14946 AGAP007394 AAEL010885 PHUM018530 GLEAN_09771
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	18112 w1118; PBac{RB}CG11188e03057/CyO 20852 y1 w67c23; P{EPgy2}CG11188EY13022/CyO
Harvard	- PBac{RB}CG11188e03057
Kyoto	114682 yd2 w1118 P{ey-FLP.N}2; P{EPgy2}CG11188EY13022 P{neoFRT}40A/CyO y+
VDRC	v106977 P{KK100453}VIE-260B v18182 w1118; P{GD7229}v18182
Genomic Clones ( 1 )
	BACR22N03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 26 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE30678
Other clones	DPiM_RE30678
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT23796 GH16211 GM05180 LD02561 LD25544 LD29217 LD30850 LD46567 RE62282
Other clones	Dmel_neb_012390_0821_2605 EK180613 EK190148 EK242249 EK242261 EP08404 RH08971 RH09344 RP001006755 RP001021993 RP001022797 RP001033895 RP001047048 RP001048372 UT01376
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0031851 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33943
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG11188 anon-WO0118547.190 (FlyBase, 1996-)
Additional comments	Source for merge of CG11188 anon-WO0118547.190 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila EST AA950741. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135222 RefSeq (Proteins) • NP_609066 DDBJ / EMBL / GenBank • AA950741 AAF52427 AAL48897 AX094066 AY071275 BI234907 CL943549 CZ480827 Entrez Gene - A searchable database of RefSeq genes. • 33943 UniProtKB/TrEMBL • Q9VM95
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • TRAUB (IPR012617)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60096 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0031851 DroID - A comprehensive database of gene and protein interactions. • FBgn0031851 DRSC - Results from RNAi screens. • FBgn0031851 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0031851 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11188-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0031851 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33943 InParanoid A subset of ortholog calls from InParanoid. • AAEL010885-PA Aedes aegypti (mosquito) AGAP007394-PA Anopheles gambiae (mosquito) XP_001122396.1 Apis mellifera (honey bee) At5g61330.1 Arabidopsis thaliana (wall cress) 86940 Batrachochytrium dendrobatidis (chytrid fungus) 106840 Branchiostoma floridae (lancelet) BGIBMGA002766-PA Bombyx mori (silk worm) ENSBTAP00000029234 Bos taurus (bovine) CAL0000848 Candida albicans (a form of yeast) CE32277 Caenorhabditis elegans (worm) ENSCAFP00000026373 Canis familiaris (dog) CAGL0H01419g Candida glabrata (haploid yeast) cn08146 Cryptococcus neoformans (yeast-like fungus) CPIJ005946 Culex pipens (mosquito) ENSCPOP00000005450 Cavia porcellus (guinea pig) 143724 Chlamidomonas reinhardtii (green alga) RP27729 Caenorhabditis remanei (nematode) ENSCSAVP00000006771 Ciona savignyi (sedentary tunicate) 110234 Capitella spl (polychaete worm) DEHA2A14212g Debaryomyces Hansenii (yeast) 308721 Daphnia pulex (daphnia) ENSDARP00000031013 Danio rerio (zebra fish) ENSECAP00000006639 Equus caballus (horse) XP_648572 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005092 Gymnopilus aculeatus (mushroom) ENSGALP00000038336 Gallus gallus (chicken) ENSP00000225402 Homo sapiens (human) ISCW007430-PA Ixodes scapularis (deer tick) KLLA0C10362g Kluyveromyces lactis (yeast) 138224 Lottia gigantea (owl limpet) LmjF20.0920 Leishmania major (virus) 31164 Monocosta brevicollis (choanoflagellate) ENSMODP00000004006 Monodelphis domestica (gray opossum) ENSMMUP00000028534 Macaca mulatta (rhesus monkey) ENSMUSP00000018841 Mus musculus (house mouse) 168185 Nematostella vectensis (starlet anemone) XP_001599692.1 Nasonia vitripennis (wasp) ENSOANP00000018241 Ornithorynchus anatinus (platypus) ENSORLP00000017094 Oryzias latipes (japanese killifish) LOC_Os01g34200.1 Oryza sativa (asian rice) PHUM006123-PA Pediculus humanus (human body louse) PP17506 Pristionchus pacificus (nematode) 89684 Physcomitrella patens (moss) ENSPPYP00000009232 Pongo pygmaeus (orangutan) 75491 Phytophthora ramorum (sudden oak death pathogen) 141125 Phytophthora sojae (root rot pathogen) 249733 Populus trichocarpa (black cottonwood) ENSPTRP00000015430 Pan troglodytes (chimpanzee) ENSRNOP00000000258 Rattus norvegicus (norway rat) 5035481 Sorghum bicolor (sorghum) YDR299W Saccharomyces cerevisiae (budding yeast) SPAC664.08c Schizosaccharomyces pombe (fission yeast) XP_001179690.1 Strongylocentrotus purpuratus (purple sea urchin) 59502 Trichoplax adhaerens (metazoa) XP_966656.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020295 Tetraodon nigroviridis (green spotted pufferfish) 24977 Thalassiosira pseudonana (marine diatom) ENSTRUP00000000315 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000019629 Xenopus tropicalis (frog) YALI0D11462g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33943 modMine - Data generated by the modENCODE project. • FBgn0031851 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB19284 NV16061 LH17018 LH17015 LH20759 ISCW007430 ISCW007431 FBgn0231703 FBgn0226762 FBgn0199694 FBgn0194810 FBgn0171124 JGI_V11_308721 FBgn0246822 FBgn0163368 FBgn0134040 FBgn0118187 FBgn0102738 FBgn0091973 CPIJ005946 BGIBMGA002766 GB14946 AGAP007394 AAEL010885 PHUM018530 GLEAN_09771
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	anon-WO0118547.190   CG11188 (FBrf0198845, Grieder et al., 2007, Grönke et al., 2007, Bharucha et al., 2008, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
	FBgn0062181
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 2 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 3 ) Protein sequence record  ( 1 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...