neuroligin, dnlg2, dnl2
Postsynaptic receptor that interacts with presynaptic Neurexins - recruits scaffolding proteins for organization of postsynaptic neurotransmitter receptors - mediates the precise apposition of presynaptic and postsynaptic membranes
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Nlg2 using the Feature Mapper tool.
In stage 16 embryos, neuroligin protein is restricted to the brain and ventral nerve cord. In third instar larva, neuroligin protein is detected in the central nervous system, co-localising with Nrx-1. neuroligin protein is highly expressed in glutamatergic type I boutons of the neuromuscular junction, which are labelled by dlg1. In synaptic boutons neuroligin protein co-localises with the synaptic markers Nrx-1, Fas2 and Syt1.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Nlg2 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.