• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Wdr82

General Information
Symbol	Dmel\Wdr82	Species	D. melanogaster
Name		Annotation symbol	CG17293
Feature type	protein_coding_gene	FlyBase ID	FBgn0032030
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	29B2-29B3	Sequence location	2L:8,374,481..8,375,549 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\Wdr82 (CG17293, FBgn0032030). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process: microtubule severing. 3 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627048_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG17293. Gene sequence location is 2L:8374481..8375549.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References Mohan et al., 2011, Mol. Cell. Biol. 31(21): 4310--4318
FB2012_01	References Ardehali et al., 2011, EMBO J. 30(14): 2817--2828 Sequence features BKN21346 HFA02595 Controlled Vocabulary Terms Set1C/COMPASS complex
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29B2-29B3   Limits computationally determined from genome sequence between P{EP}EP646EP646&P{lacW}RpS13k09614 and P{lacW}l(2)k12914k12914&P{lacW}Akap200k07118a
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Wdr82 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Wdr82-RA FBtr0079650  NM_135373   1069   317
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Wdr82-PA   FBpp0079266   35.4   317   7.27     NP_609217   AAF52654
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40-repeat-containing domain (IPR017986) WD40/YVTN repeat-like-containing domain (IPR015943) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782) G-protein beta WD-40 repeat (IPR020472)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA942367   AE014134 AAF52654   AI110152   AI389476   AI402182   AI512780   AI533789   AY069081 AAL39226   BI358554   BI369656   BI580111   BI580848   BI638437   CL528139   CO155161   CO155699   CO185808   CO336918   EC229053   EC229864   EC266049   EV580057   EV584006
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VLN1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032030    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032030 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032030 expression level Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4854) embryo 02-04hr  (6412) embryo 04-06hr  (6296) embryo 06-08hr  (5037) embryo 08-10hr  (4782) embryo 10-12hr  (4111) embryo 12-14hr  (2847) embryo 14-16hr  (2872) embryo 16-18hr  (2133) embryo 18-20hr  (1375) embryo 20-22hr  (1350) embryo 22-24hr  (1458) larva L1  (1782) larva L2  (1560) larva L3 12hr old  (1244) larva L3 puffstage 1-2  (1501) larva L3 puffstage 3-6  (1866) larva L3 puffstage 7-9  (2275) white prepupae new  (2386) white prepupae 12hr  (2764) white prepupae 24hr  (2714) pupae 2d postWPP  (2221) pupae 3d postWPP  (1415) pupae 4d postWPP  (1266) adult male 01day  (1419) adult male 05day  (1418) adult male 30day  (1825) adult female 01day  (2265) adult female 05day  (2723) adult female 30day  (2635) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4854) embryo 02-04hr  (6412) embryo 04-06hr  (6296) embryo 06-08hr  (5037) embryo 08-10hr  (4782) embryo 10-12hr  (4111) embryo 12-14hr  (2847) embryo 14-16hr  (2872) embryo 16-18hr  (2133) embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr  1458 larva L1  (1782) larva L2  (1560) larva L3 12hr old    1244 larva L3 puffstage 1-2  1501 larva L3 puffstage 3-6  (1866) larva L3 puffstage 7-9  (2275) white prepupae new  (2386) white prepupae 12hr  (2764) white prepupae 24hr  (2714) pupae 2d postWPP  (2221) pupae 3d postWPP  1415 pupae 4d postWPP    1266 adult male 01day  1419 adult male 05day  1418 adult male 30day  (1825) adult female 01day  (2265) adult female 05day  (2723) adult female 30day  (2635) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032030 expression level Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4854) embryo 02-04hr  (6412) embryo 04-06hr  (6296) embryo 06-08hr  (5037) embryo 08-10hr  (4782) embryo 10-12hr  (4111) embryo 12-14hr  (2847) embryo 14-16hr  (2872) embryo 16-18hr  (2133) embryo 18-20hr  (1375) embryo 20-22hr  (1350) embryo 22-24hr  (1458) larva L1  (1782) larva L2  (1560) larva L3 12hr old  (1244) larva L3 puffstage 1-2  (1501) larva L3 puffstage 3-6  (1866) larva L3 puffstage 7-9  (2275) white prepupae new  (2386) white prepupae 12hr  (2764) white prepupae 24hr  (2714) pupae 2d postWPP  (2221) pupae 3d postWPP  (1415) pupae 4d postWPP  (1266) adult male 01day  (1419) adult male 05day  (1418) adult male 30day  (1825) adult female 01day  (2265) adult female 05day  (2723) adult female 30day  (2635) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4854) embryo 02-04hr  (6412) embryo 04-06hr  (6296) embryo 06-08hr  (5037) embryo 08-10hr  (4782) embryo 10-12hr  (4111) embryo 12-14hr  (2847) embryo 14-16hr  (2872) embryo 16-18hr  2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr  1458 larva L1  1782 larva L2  1560 larva L3 12hr old    1244 larva L3 puffstage 1-2  1501 larva L3 puffstage 3-6  1866 larva L3 puffstage 7-9  2275 white prepupae new  2386 white prepupae 12hr  (2764) white prepupae 24hr  (2714) pupae 2d postWPP  2221 pupae 3d postWPP  1415 pupae 4d postWPP    1266 adult male 01day  1419 adult male 05day  1418 adult male 30day  1825 adult female 01day  2265 adult female 05day  (2723) adult female 30day  (2635) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4854 embryo 02-04hr    6412 embryo 04-06hr    6296 embryo 06-08hr    5037 embryo 08-10hr    4782 embryo 10-12hr    4111 embryo 12-14hr    2847 embryo 14-16hr    2872 embryo 16-18hr    2133 embryo 18-20hr    1375 embryo 20-22hr    1350 embryo 22-24hr    1458 larva L1    1782 larva L2    1560 larva L3 12hr old    1244 larva L3 puffstage 1-2    1501 larva L3 puffstage 3-6    1866 larva L3 puffstage 7-9    2275 white prepupae new    2386 white prepupae 12hr    2764 white prepupae 24hr    2714 pupae 2d postWPP    2221 pupae 3d postWPP    1415 pupae 4d postWPP    1266 adult male 01day    1419 adult male 05day    1418 adult male 30day    1825 adult female 01day    2265 adult female 05day    2723 adult female 30day    2635 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032030    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032030 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032030 expression level Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032030 expression level Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    396.225 Larval Midgut    135.6 Larval Hindgut    164.1 Larval Malpighian Tubules    198 Larval Fat Body    200.1 Larval Salivary Gland    376.2 Larval Trachea    301.35 Larval Carcass    159.45 Adult Head    164.2 Adult Eye    291.275 Adult Brain    209.4 Adult Thoracic-Abdominal Ganglion    236.1 Adult Crop    177.2 Adult Midgut no informative data Adult Hindgut    145 Adult Malpighian Tubules    165 Adult Fat Body    136.5 Adult Salivary Gland    301.3 Adult Heart    178.625 Adult VirginFemale Spermatheca    176.4 Adult InseminatedFemale Spermatheca    188.8 Adult Ovary    330.5 Adult Testis    96.3 Adult Male Accessory Gland    284.5 Adult Carcass    121.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    164.2   NA  Eye    291.275   NA  Brain    209.4   396.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    236.1   NA  Crop    177.2   135.6  Midgut    no informative data   164.1  Hindgut    145   198  Malpighian Tubules    165   200.1  Fat Body    136.5   376.2  Salivary Gland    301.3   NA  Heart    178.625   301.35  Trachea    NA   NA  VirginFemale Spermatheca    176.4   NA  InseminatedFemale Spermatheca    188.8   NA  Ovary    330.5   NA  Testis    96.3   NA  Male Accessory Gland    284.5   159.45  Carcass    121.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032030 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17293-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Wdr82EY08939 viable, with Scer\GAL4pnr-MD237 Wdr82GD9340 Sterility Allele fertile Wdr82EY08939 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 Wdr82GD9340 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 Wdr82GD9340
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Wdr82 Class Mutagen Stocks Known lesion Wdr82EY08939 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Wdr82 Class Mutagen Stocks Known lesion Wdr82GD9340 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Wdr82HMS00718 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}Wdr82EY08939 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
Set1C/COMPASS complex inferred from direct assay (Ardehali et al., 2011)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
microtubule severing inferred from sequence or structural similarity with EMBL:AF052432 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
katanin complex inferred from sequence or structural similarity with EMBL:AF052432 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Wdr82 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60277 DroID - A comprehensive database of gene and protein interactions. • FBgn0032030 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34153
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15223 Dere\GG10542 Dgri\GH10840 Dmoj\GI17354 Dper\GL25937 Dpse\GA14445 Dsec\GM16920 Dsim\GD23532 Dvir\GJ16174 Dwil\GK24839 Dyak\GE18763
Curated drosophilid orthologs	Dpse\GA14445
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001211-PA Aedes aegypti (mosquito) AGAP009700-PA Anopheles gambiae (mosquito) XP_395346.1 Apis mellifera (honey bee) XP_001949091.1 Acyrthosiphon pisum (pea aphid) At5g14530.1 Arabidopsis thaliana (wall cress) 10205 Batrachochytrium dendrobatidis (chytrid fungus) 9730 Batrachochytrium dendrobatidis (chytrid fungus) 60243 Branchiostoma floridae (lancelet) BGIBMGA005930-PA Bombyx mori (silk worm) ENSBTAP00000043205 Bos taurus (bovine) CAL0004300 Candida albicans (a form of yeast) CN13731 Caenorhabditis brenneri (small nematode) CBP18987 Caenorhabditis briggsae (nematode) CE04150 Caenorhabditis elegans (worm) ENSCAFP00000014477 Canis familiaris (dog) CAGL0L09757g Candida glabrata (haploid yeast) ENSCINP00000018469 Ciona intestinalis (sea squirt) JA11695 Caenorhabditis japonica (nematode) CMQ050C Cyanidioschyzon merolae (red alga) cn03716 Cryptococcus neoformans (yeast-like fungus) cgd8_3960 Cryptosporidium parvum (protozoan parasite) CPIJ005918 Culex pipens (mosquito) ENSCPOP00000009441 Cavia porcellus (guinea pig) RP23796 Caenorhabditis remanei (nematode) ENSCSAVP00000001084 Ciona savignyi (sedentary tunicate) 164497 Capitella spl (polychaete worm) 184348 Capitella spl (polychaete worm) DDB0218126 Dictyostelium discoideum (amoeba) DEHA2F25696g Debaryomyces Hansenii (yeast) 300247 Daphnia pulex (daphnia) ENSDARP00000024168 Danio rerio (zebra fish) XP_654195 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001654 Gymnopilus aculeatus (mushroom) ENSGALP00000006327 Gallus gallus (chicken) 189760 Hypsipyla robusta (cedar shoot borer) ENSP00000296490 Homo sapiens (human) ISCW012635-PA Ixodes scapularis (deer tick) KLLA0E18063g Kluyveromyces lactis (yeast) 231033 Lottia gigantea (owl limpet) ENSMODP00000014538 Monodelphis domestica (gray opossum) ENSMMUP00000010790 Macaca mulatta (rhesus monkey) ENSMUSP00000020490 Mus musculus (house mouse) 207760 Nematostella vectensis (starlet anemone) XP_001604288.1 Nasonia vitripennis (wasp) ENSOANP00000021466 Ornithorynchus anatinus (platypus) ENSORLP00000004824 Oryzias latipes (japanese killifish) LOC_Os05g46570.1 Oryza sativa (asian rice) 28201 Ostreococcus tauri (green alga) PFL2105c Plasmodium falciparum (protozoal parasite) PHUM001064-PA Pediculus humanus (human body louse) PP28662 Pristionchus pacificus (nematode) 187732 Physcomitrella patens (moss) ENSPPYP00000016187 Pongo pygmaeus (orangutan) 76158 Phytophthora ramorum (sudden oak death pathogen) 134212 Phytophthora sojae (root rot pathogen) 706765 Populus trichocarpa (black cottonwood) ENSPTRP00000025885 Pan troglodytes (chimpanzee) PVX_101090 Plasmodium vivax (protozoal parasite) ENSRNOP00000055862 Rattus norvegicus (norway rat) 146514 Sorghum bicolor (sorghum) YKL018W Saccharomyces cerevisiae (budding yeast) Smp_151180 Schistosoma mansoni (trematode parasite) SPBC18H10.06c Schizosaccharomyces pombe (fission yeast) XP_001183944.1 Strongylocentrotus purpuratus (purple sea urchin) 49741 Trichoplax adhaerens (metazoa) TA16630 Theileria annulata (apicomplexan parasite) XP_966556.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017808 Tetraodon nigroviridis (green spotted pufferfish) TP01_0986 Theileria parva (parasitic protozoan) 36476 Thalassiosira pseudonana (marine diatom) ENSTRUP00000035189 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000006015 Xenopus tropicalis (frog) YALI0F21263g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18499 NV14890 LH14924 ISCW012635 FBgn0236152 FBgn0226798 FBgn0203359 FBgn0194910 FBgn0171833 JGI_V11_300247 FBgn0074473 FBgn0163521 FBgn0140098 FBgn0118321 FBgn0102850 FBgn0092248 CPIJ005918 BGIBMGA005930 ACYPI003455 GB13929 AGAP009700 AAEL001211 PHUM249650 GLEAN_14755
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	16438 y1 w67c23; P{EPgy2}Wdr82EY08939 32926 y1 sc* v1; P{TRiP.HMS00718}attP2
VDRC	v25246 w1118; P{GD9340}v25246 v25248 w1118; P{GD9340}v25248
Genomic Clones ( 1 )
	BACR15P08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 19 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH09638
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH20657 LD26526 LD44810 RE45355 RE55909 RE74248 RE75085 SD05750
Other clones	561981 CK01.10B.G6 CK01.56C.E8 Dmel_dig_010242_0650_0345 Dmel_dig_018815_0685_2349 EK012559 EN05502 EN06602 EN13464 SD20728
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032030 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34153
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Wdr82 CG17293 (Ardehali et al., 2011)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135373 RefSeq (Proteins) • NP_609217 DDBJ / EMBL / GenBank • AAF52654 AAL39226 AI110152 AI402182 AY069081 CL528139 Entrez Gene - A searchable database of RefSeq genes. • 34153 UniProtKB/TrEMBL • Q9VLN1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40-repeat-containing domain (IPR017986) WD40/YVTN repeat-like-containing domain (IPR015943) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782) G-protein beta WD-40 repeat (IPR020472)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60277 DroID - A comprehensive database of gene and protein interactions. • FBgn0032030 DRSC - Results from RNAi screens. • FBgn0032030 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032030 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17293-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032030 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34153 InParanoid A subset of ortholog calls from InParanoid. • AAEL001211-PA Aedes aegypti (mosquito) AGAP009700-PA Anopheles gambiae (mosquito) XP_395346.1 Apis mellifera (honey bee) XP_001949091.1 Acyrthosiphon pisum (pea aphid) At5g14530.1 Arabidopsis thaliana (wall cress) 10205 Batrachochytrium dendrobatidis (chytrid fungus) 9730 Batrachochytrium dendrobatidis (chytrid fungus) 60243 Branchiostoma floridae (lancelet) BGIBMGA005930-PA Bombyx mori (silk worm) ENSBTAP00000043205 Bos taurus (bovine) CAL0004300 Candida albicans (a form of yeast) CN13731 Caenorhabditis brenneri (small nematode) CBP18987 Caenorhabditis briggsae (nematode) CE04150 Caenorhabditis elegans (worm) ENSCAFP00000014477 Canis familiaris (dog) CAGL0L09757g Candida glabrata (haploid yeast) ENSCINP00000018469 Ciona intestinalis (sea squirt) JA11695 Caenorhabditis japonica (nematode) CMQ050C Cyanidioschyzon merolae (red alga) cn03716 Cryptococcus neoformans (yeast-like fungus) cgd8_3960 Cryptosporidium parvum (protozoan parasite) CPIJ005918 Culex pipens (mosquito) ENSCPOP00000009441 Cavia porcellus (guinea pig) RP23796 Caenorhabditis remanei (nematode) ENSCSAVP00000001084 Ciona savignyi (sedentary tunicate) 164497 Capitella spl (polychaete worm) 184348 Capitella spl (polychaete worm) DDB0218126 Dictyostelium discoideum (amoeba) DEHA2F25696g Debaryomyces Hansenii (yeast) 300247 Daphnia pulex (daphnia) ENSDARP00000024168 Danio rerio (zebra fish) XP_654195 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001654 Gymnopilus aculeatus (mushroom) ENSGALP00000006327 Gallus gallus (chicken) 189760 Hypsipyla robusta (cedar shoot borer) ENSP00000296490 Homo sapiens (human) ISCW012635-PA Ixodes scapularis (deer tick) KLLA0E18063g Kluyveromyces lactis (yeast) 231033 Lottia gigantea (owl limpet) ENSMODP00000014538 Monodelphis domestica (gray opossum) ENSMMUP00000010790 Macaca mulatta (rhesus monkey) ENSMUSP00000020490 Mus musculus (house mouse) 207760 Nematostella vectensis (starlet anemone) XP_001604288.1 Nasonia vitripennis (wasp) ENSOANP00000021466 Ornithorynchus anatinus (platypus) ENSORLP00000004824 Oryzias latipes (japanese killifish) LOC_Os05g46570.1 Oryza sativa (asian rice) 28201 Ostreococcus tauri (green alga) PFL2105c Plasmodium falciparum (protozoal parasite) PHUM001064-PA Pediculus humanus (human body louse) PP28662 Pristionchus pacificus (nematode) 187732 Physcomitrella patens (moss) ENSPPYP00000016187 Pongo pygmaeus (orangutan) 76158 Phytophthora ramorum (sudden oak death pathogen) 134212 Phytophthora sojae (root rot pathogen) 706765 Populus trichocarpa (black cottonwood) ENSPTRP00000025885 Pan troglodytes (chimpanzee) PVX_101090 Plasmodium vivax (protozoal parasite) ENSRNOP00000055862 Rattus norvegicus (norway rat) 146514 Sorghum bicolor (sorghum) YKL018W Saccharomyces cerevisiae (budding yeast) Smp_151180 Schistosoma mansoni (trematode parasite) SPBC18H10.06c Schizosaccharomyces pombe (fission yeast) XP_001183944.1 Strongylocentrotus purpuratus (purple sea urchin) 49741 Trichoplax adhaerens (metazoa) TA16630 Theileria annulata (apicomplexan parasite) XP_966556.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017808 Tetraodon nigroviridis (green spotted pufferfish) TP01_0986 Theileria parva (parasitic protozoan) 36476 Thalassiosira pseudonana (marine diatom) ENSTRUP00000035189 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000006015 Xenopus tropicalis (frog) YALI0F21263g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34153 modMine - Data generated by the modENCODE project. • FBgn0032030 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18499 NV14890 LH14924 ISCW012635 FBgn0236152 FBgn0226798 FBgn0203359 FBgn0194910 FBgn0171833 JGI_V11_300247 FBgn0074473 FBgn0163521 FBgn0140098 FBgn0118321 FBgn0102850 FBgn0092248 CPIJ005918 BGIBMGA005930 ACYPI003455 GB13929 AGAP009700 AAEL001211 PHUM249650 GLEAN_14755
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG17293 (Zhou et al., 2008, Ni et al., 2010.12.1, Ardehali et al., 2011, Somma et al., 2008) dWdr82 (Ardehali et al., 2011) Wdr82
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Ardehali et al., 2011, EMBO J. 30(14): 2817--2828 Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription. [FBrf0214333] Mohan et al., 2011, Mol. Cell. Biol. 31(21): 4310--4318 The COMPASS Family of H3K4 Methylases in Drosophila. [FBrf0216343] Somma et al., 2008, PLoS Genet. 4(7): e1000126 Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. [FBrf0206064] Zhou et al., 2008, Mol. Cell 32(4): 592--599 Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. [FBrf0206362]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]