FB2019_05, released Oct 15, 2019

Gene: Dmel\Sgp

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General Information
Symbol
Dmel\Sgp
Species
D. melanogaster
Name
Sgroppino
Annotation Symbol
CG13091
Feature Type
protein_coding_gene
FlyBase ID
FBgn0032055
Gene Model Status
Current
Stock Availability
4 publicly available
Gene Snapshot
Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
29D4-29D4
Sequence location
2L:8,519,690..8,521,809 [+]
Recombination map
2-33
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
-
Predictions / Assertions
fatty-acyl-CoA reductase (alcohol-forming) activity
Summaries
Gene Group (FlyBase)
ALDEHYDE OR OXO OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR -
Aldehyde or oxo oxidoreductases with NAD or NADP as acceptor, include dehydrogenases that oxidize an aldehyde or ketone (oxo) group with the reduction of NAD or NADP.
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\Sgp or the JBrowse view of Dmel\Sgp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.46
Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Sgp-RA
FBtr0079684
NM_135397
1718
523
Sgp-RB
FBtr0333415
NM_001273328
1796
523
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Sgp-PA
FBpp0079296
59.5
523
9.36
NP_609241
AAF52692
Sgp-PB
FBpp0305607
59.5
523
9.36
NP_001260257
AGB92793
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

523 aa isoforms: Sgp-PA, Sgp-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sgp using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (3 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
fatty-acyl-CoA reductase (alcohol-forming) activity
inferred from sequence or structural similarity with HGNC:26222
(Faust et al., 2012)
inferred from biological aspect of ancestor with PANTHER:PTN000110226
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
long-chain fatty-acyl-CoA metabolic process
inferred from biological aspect of ancestor with PANTHER:PTN000110226
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
peroxisome
inferred from biological aspect of ancestor with PANTHER:PTN000110227
(assigned by GO_Central )
(Gaudet et al., 2011)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
expression microarray
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult fat body

Comment: cyclical, peak ZT21-0

(Xu et al., 2011)
Additional Descriptive Data
Expressed cyclically in the adult fat body.
(Xu et al., 2011)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Sgp in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 2 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Sgp
Transgenic constructs containing regulatory region of Sgp
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\FAR2
5 of 15
Yes
No
Hsap\FAR1
4 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Far2
4 of 15
Yes
No
Mmus\Far1
3 of 15
No
No
Rattus norvegicus (Norway rat) (2)
Rnor\Far2
4 of 13
Yes
No
Rnor\Far1
2 of 13
No
No
Xenopus tropicalis (Western clawed frog) (1)
Xtro\far1
3 of 12
Yes
No
Danio rerio (Zebrafish) (2)
Drer\si:dkey-97m3.1
4 of 15
Yes
No
Drer\far1
2 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\fard-1
3 of 15
Yes
No
Arabidopsis thaliana (thale-cress) (9)
Atha\CER4
7 of 9
Yes
No
Atha\FAR4
7 of 9
Yes
No
Atha\FAR5
7 of 9
Yes
No
Atha\FAR8
7 of 9
Yes
No
Atha\FAR1
6 of 9
No
No
Atha\FAR6
6 of 9
No
No
Atha\FAR7
6 of 9
No
No
Atha\MS2
5 of 9
No
No
Atha\AT3G60060
1 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\LYS2
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPCC162.02c
1 of 12
Yes
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG0919061Y )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\Sgp
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00006722
Drosophila simulans
Dsim\GD23553
Drosophila erecta
Dere\GG25292
Drosophila yakuba
Dyak\GE18784
Drosophila pseudoobscura pseudoobscura
Dpse\GA24999
Drosophila pseudoobscura pseudoobscura
Dpse\GA32357
Drosophila persimilis
Dper\GL27182
Drosophila persimilis
Dper\GL16950
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503GL )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17022038
Musca domestica
House fly
Mdoa\17021518
Musca domestica
House fly
Mdoa\17019945
Musca domestica
House fly
Mdoa\17016335
Glossina morsitans
Tsetse fly
Gmor\GMOY003427
Glossina morsitans
Tsetse fly
Gmor\GMOY011618
Glossina morsitans
Tsetse fly
Gmor\GMOY009401
Glossina morsitans
Tsetse fly
Gmor\GMOY009983
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_03294
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_02195
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_13084
Mayetiola destructor
Hessian fly
Mdes\Mdes005397
Mayetiola destructor
Hessian fly
Mdes\Mdes000919
Mayetiola destructor
Hessian fly
Mdes\Mdes011173
Mayetiola destructor
Hessian fly
Mdes\Mdes001211
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL006774
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013802
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL007298
Anopheles darlingi
American malaria mosquito
Adar\ADAC006947
Anopheles darlingi
American malaria mosquito
Adar\ADAC000188
Anopheles gambiae
Malaria mosquito
Agam\AGAP011736
Anopheles gambiae
Malaria mosquito
Agam\AGAP009690
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ018289
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ014976
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W042P )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA011148
Bombyx mori
Silkmoth
Bmor\BGIBMGA011207
Bombyx mori
Silkmoth
Bmor\BGIBMGA006569
Bombyx mori
Silkmoth
Bmor\BGIBMGA011395
Bombyx mori
Silkmoth
Bmor\BGIBMGA011217
Bombyx mori
Silkmoth
Bmor\BGIBMGA011149
Bombyx mori
Silkmoth
Bmor\BGIBMGA011398
Bombyx mori
Silkmoth
Bmor\BGIBMGA011145
Bombyx mori
Silkmoth
Bmor\BGIBMGA011116
Bombyx mori
Silkmoth
Bmor\BGIBMGA000659
Danaus plexippus
Monarch butterfly
Dple\DPOGS211701-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS210773-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211704-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS200887-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS200094-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS206089-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211700-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS208129-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211698-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS210763-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211702-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS208850-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211692-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL009811
Heliconius melpomene
Postman butterfly
Hmel\HMEL013891
Heliconius melpomene
Postman butterfly
Hmel\HMEL003182
Heliconius melpomene
Postman butterfly
Hmel\HMEL012267
Heliconius melpomene
Postman butterfly
Hmel\HMEL009864
Heliconius melpomene
Postman butterfly
Hmel\HMEL013888
Heliconius melpomene
Postman butterfly
Hmel\HMEL014878
Heliconius melpomene
Postman butterfly
Hmel\HMEL016715
Heliconius melpomene
Postman butterfly
Hmel\HMEL006340
Heliconius melpomene
Postman butterfly
Hmel\HMEL013886
Apis florea
Little honeybee
Aflo\2362588932
Apis florea
Little honeybee
Aflo\2880507284
Apis florea
Little honeybee
Aflo\4428147508
Apis florea
Little honeybee
Aflo\2147484401
Apis florea
Little honeybee
Aflo\2609990804
Apis florea
Little honeybee
Aflo\2362589396
Apis florea
Little honeybee
Aflo\2362588740
Apis florea
Little honeybee
Aflo\2362588868
Apis florea
Little honeybee
Aflo\2362588788
Apis mellifera
Western honey bee
Amel\LOC413295
Apis mellifera
Western honey bee
Amel\GB55263
Apis mellifera
Western honey bee
Amel\LOC411983
Apis mellifera
Western honey bee
Amel\GB49326
Apis mellifera
Western honey bee
Amel\LOC412986
Apis mellifera
Western honey bee
Amel\LOC552110
Apis mellifera
Western honey bee
Amel\GB52087
Apis mellifera
Western honey bee
Amel\FAR1
Apis mellifera
Western honey bee
Amel\GB49323
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP22123
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP22125
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11196
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP12705
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14571
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11772
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP25747
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14126
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP22124
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19914
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11759
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15350
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14134
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP17389
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP12696
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP17392
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14128
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11773
Bombus terrestris
Buff-tailed bumblebee
Bter\15202497
Bombus terrestris
Buff-tailed bumblebee
Bter\15202549
Bombus terrestris
Buff-tailed bumblebee
Bter\15203607
Bombus terrestris
Buff-tailed bumblebee
Bter\15202590
Bombus terrestris
Buff-tailed bumblebee
Bter\15211361
Bombus terrestris
Buff-tailed bumblebee
Bter\15203832
Bombus terrestris
Buff-tailed bumblebee
Bter\15213249
Bombus terrestris
Buff-tailed bumblebee
Bter\15202065
Bombus terrestris
Buff-tailed bumblebee
Bter\15201649
Bombus terrestris
Buff-tailed bumblebee
Bter\15213264
Bombus terrestris
Buff-tailed bumblebee
Bter\15211368
Bombus terrestris
Buff-tailed bumblebee
Bter\15202589
Bombus terrestris
Buff-tailed bumblebee
Bter\15213267
Bombus terrestris
Buff-tailed bumblebee
Bter\15203615
Bombus terrestris
Buff-tailed bumblebee
Bter\15211868
Bombus terrestris
Buff-tailed bumblebee
Bter\15213266
Bombus terrestris
Buff-tailed bumblebee
Bter\15201912
Bombus terrestris
Buff-tailed bumblebee
Bter\15213336
Bombus terrestris
Buff-tailed bumblebee
Bter\15213265
Bombus terrestris
Buff-tailed bumblebee
Bter\15202580
Bombus terrestris
Buff-tailed bumblebee
Bter\15202813
Linepithema humile
Argentine ant
Lhum\LH20453
Linepithema humile
Argentine ant
Lhum\LH11288
Linepithema humile
Argentine ant
Lhum\LH11789
Linepithema humile
Argentine ant
Lhum\LH10353
Linepithema humile
Argentine ant
Lhum\LH11637
Linepithema humile
Argentine ant
Lhum\LH17094
Linepithema humile
Argentine ant
Lhum\LH17363
Linepithema humile
Argentine ant
Lhum\LH10411
Linepithema humile
Argentine ant
Lhum\LH11788
Linepithema humile
Argentine ant
Lhum\LH13324
Linepithema humile
Argentine ant
Lhum\LH11790
Linepithema humile
Argentine ant
Lhum\LH16822
Linepithema humile
Argentine ant
Lhum\LH16435
Linepithema humile
Argentine ant
Lhum\LH13325
Linepithema humile
Argentine ant
Lhum\LH10910
Linepithema humile
Argentine ant
Lhum\LH16824
Linepithema humile
Argentine ant
Lhum\LH16821
Linepithema humile
Argentine ant
Lhum\LH15114
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001b0f
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001321
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002953
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001c0e
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00295d
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00295e
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001b0d
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0009c8
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001b10
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015690
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011573
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013812
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011569
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015694
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG025693
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015692
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015686
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG017065
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG017071
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG000624
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG032705
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG017070
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004940
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011574
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015695
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_06489
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_05940
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11468
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08411
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08332
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09776
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_10828
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04673
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_02157
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15051
Tribolium castaneum
Red flour beetle
Tcas\TC009834
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15111
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15380
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15052
Tribolium castaneum
Red flour beetle
Tcas\TC009785
Tribolium castaneum
Red flour beetle
Tcas\TC010578
Tribolium castaneum
Red flour beetle
Tcas\TC033617
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15753
Tribolium castaneum
Red flour beetle
Tcas\TC009833
Tribolium castaneum
Red flour beetle
Tcas\TC000107
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_14982
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15203
Tribolium castaneum
Red flour beetle
Tcas\TC011214
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15379
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15188
Tribolium castaneum
Red flour beetle
Tcas\TC033959
Tribolium castaneum
Red flour beetle
Tcas\TC033309
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15381
Tribolium castaneum
Red flour beetle
Tcas\TC011283
Tribolium castaneum
Red flour beetle
Tcas\TC006124
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_15576
Tribolium castaneum
Red flour beetle
Tcas\TC006096
Pediculus humanus
Human body louse
Phum\PHUM365940
Pediculus humanus
Human body louse
Phum\PHUM285160
Pediculus humanus
Human body louse
Phum\PHUM288740
Pediculus humanus
Human body louse
Phum\PHUM288600
Pediculus humanus
Human body louse
Phum\PHUM288630
Pediculus humanus
Human body louse
Phum\PHUM423990
Pediculus humanus
Human body louse
Phum\PHUM536800
Pediculus humanus
Human body louse
Phum\PHUM288620
Pediculus humanus
Human body louse
Phum\PHUM091870
Pediculus humanus
Human body louse
Phum\PHUM424180
Pediculus humanus
Human body louse
Phum\PHUM561380
Rhodnius prolixus
Kissing bug
Rpro\RPRC000258
Rhodnius prolixus
Kissing bug
Rpro\RPRC014002
Rhodnius prolixus
Kissing bug
Rpro\RPRC006662
Rhodnius prolixus
Kissing bug
Rpro\RPRC014004
Rhodnius prolixus
Kissing bug
Rpro\RPRC013997
Rhodnius prolixus
Kissing bug
Rpro\RPRC006042
Rhodnius prolixus
Kissing bug
Rpro\RPRC013998
Rhodnius prolixus
Kissing bug
Rpro\RPRC011813
Rhodnius prolixus
Kissing bug
Rpro\RPRC000525
Rhodnius prolixus
Kissing bug
Rpro\RPRC001961
Rhodnius prolixus
Kissing bug
Rpro\RPRC013697
Rhodnius prolixus
Kissing bug
Rpro\RPRC000880
Rhodnius prolixus
Kissing bug
Rpro\RPRC005892
Rhodnius prolixus
Kissing bug
Rpro\RPRC003632
Rhodnius prolixus
Kissing bug
Rpro\RPRC011486
Cimex lectularius
Bed bug
Clec\CLEC006575
Cimex lectularius
Bed bug
Clec\CLEC012469
Cimex lectularius
Bed bug
Clec\CLEC004788
Cimex lectularius
Bed bug
Clec\CLEC001287
Cimex lectularius
Bed bug
Clec\CLEC003009
Cimex lectularius
Bed bug
Clec\CLEC008174
Cimex lectularius
Bed bug
Clec\CLEC006582
Cimex lectularius
Bed bug
Clec\CLEC004177
Cimex lectularius
Bed bug
Clec\CLEC006578
Cimex lectularius
Bed bug
Clec\CLEC006335
Cimex lectularius
Bed bug
Clec\CLEC006583
Cimex lectularius
Bed bug
Clec\CLEC011843
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI007830
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004919
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006230
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI005217
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009391
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001657
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI071288
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001144
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002672
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI007169
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004140
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008817
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008061
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004106
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009674
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008823
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004092
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003622
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003321
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI28767
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01499
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02455
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_18566
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_18718
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05776
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_15619
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01501
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13958
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_15958
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_14898
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05262
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05261
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03Z9 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR004348
Strigamia maritima
European centipede
Smar\SMAR012110
Strigamia maritima
European centipede
Smar\SMAR003122
Strigamia maritima
European centipede
Smar\SMAR014707
Strigamia maritima
European centipede
Smar\SMAR015266
Strigamia maritima
European centipede
Smar\SMAR014842
Ixodes scapularis
Black-legged tick
Isca\ISCW009857
Ixodes scapularis
Black-legged tick
Isca\ISCW021433
Ixodes scapularis
Black-legged tick
Isca\ISCW017626
Ixodes scapularis
Black-legged tick
Isca\ISCW003967
Ixodes scapularis
Black-legged tick
Isca\ISCW020491
Ixodes scapularis
Black-legged tick
Isca\ISCW021430
Ixodes scapularis
Black-legged tick
Isca\ISCW017498
Stegodyphus mimosarum
African social velvet spider
Smim\KFM73769.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65961.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur04g01060
Tetranychus urticae
Two-spotted spider mite
Turt\tetur08g03120
Tetranychus urticae
Two-spotted spider mite
Turt\tetur38g00570
Tetranychus urticae
Two-spotted spider mite
Turt\tetur38g00560
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g10530
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g08890
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_201098
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_54548
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_321695
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_319586
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_304883
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_213553
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_304841
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_233376
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_61438
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_54566
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_54466
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_54498
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_46833
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_304882
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G062W )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Far1
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000014293
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000014291
Gallus gallus
Domestic chicken
Ggal\FAR1
Gallus gallus
Domestic chicken
Ggal\FAR2
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (16)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG14893
6 of 10
CG17562
6 of 10
CG30427
6 of 10
CG1441
5 of 10
CG4020
5 of 10
CG4770
5 of 10
CG5065
5 of 10
CG8303
5 of 10
CG8306
5 of 10
CG10096
5 of 10
CG10097
5 of 10
CG12268
5 of 10
CG17560
5 of 10
CG34342
5 of 10
wat
5 of 10
FarO
3 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    FAR2; fatty acyl-CoA reductase 2
    5 of 15
    616156
        FAR1; fatty acyl-CoA reductase 1
        4 of 15
        616107
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Interactions Browser
          Summary of Genetic Interactions
          esyN Network Diagram
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          Pathways
          Gene Group - Pathway Membership (FlyBase)
          External Data
          Linkouts
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          2L
          Recombination map
          2-33
          Cytogenetic map
          29D4-29D4
          Sequence location
          2L:8,519,690..8,521,809 [+]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          29D4-29D4
          Limits computationally determined from genome sequence between P{lacW}l(2)k03706k03706&P{lacW}Acerk07704 and P{PZ}lmg03424
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location
          2-33
          (FlyBase, 2016)
          2-28.4
          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (4)
          Genomic Clones (13)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (2)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequences
          BDGP DGC clones
          Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of
              Source for identity of: Sgp CG13091
              (Merkling et al., 2019)
              Source for database merge of
              Additional comments
              Other Comments
              Origin and Etymology
              Discoverer
              Etymology
              Named 'Sgroppino' because, after removal of the digestive track and reproductive system, a relatively larger mass of fat body tissue remains loosely attached to the abdominal carcass in mutants, forming large oleaginous droplets and appearing white - reminiscent of the Sgroppino cocktail.
              (Merkling et al., 2019)
              Identification
              External Crossreferences and Linkouts ( 35 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
              modMine - A data warehouse for the modENCODE project
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Linkouts
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FLIGHT - Cell culture data for RNAi and other high-throughput technologies
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyMine - An integrated database for Drosophila genomics
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Synonyms and Secondary IDs (4)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (33)