Gene Dmel\CG9468

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General Information

Symbol

Dmel\CG9468

Species

D. melanogaster

Name

Annotation symbol

CG9468

Feature type

protein_coding_gene

FlyBase ID

FBgn0032069

Gene Model Status

Current

Stock availability

3 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

29F1-29F1

Sequence location

2L:8,777,661..8,781,252 [-]

Genomic Maps

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Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG9468 (FBgn0032069). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: alpha-mannosidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: mannose metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase, family 38, central domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase family 38, C-terminal; Glycosyl hydrolase, family 13, all-beta. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Comments on Affy2 ProbeSet: ProbeSet 1636395_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9468. Gene sequence location is 2L:8777661..8781252.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

29F1-29F1

Limits computationally determined from genome sequence between P{lacW}l(2)k04003^k04003 and P{PZ}tai⁰¹³⁵¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG9468 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG9468-RA

FBtr0079741

NM_135409

3160

1007

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG9468-PA

FBpp0079343

114.9

1007

5.10

NP_609253

AAF52711

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Glycoside hydrolase family 38, N-terminal domain (IPR000602)

Galactose mutarotase-like domain (IPR011013)

Glycosyl hydrolase family 38, C-terminal (IPR011682)

Glycoside hydrolase/deacetylase, beta/alpha-barrel (IPR011330)

Glycosyl hydrolase, family 13, all-beta (IPR013780)

Glycoside hydrolase, family 38, central domain (IPR015341)

Glycoside hydrolase 38/57, N-terminal domain (IPR027291)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

posterior spiracle primordium

(Fisher et al., 2012)

Comment:reported as posterior spiracle specific anlage

embryonic stage 13 -- 16

embryonic/larval midgut

(Fisher et al., 2012)

embryonic/larval posterior spiracle

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		3930.4
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		4010
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		(3930.4)
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		(4010)
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		(3930.4)
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		(4010)
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		3930.4
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		4010
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		3930.4
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		4010
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		(3930.4)
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		(4010)
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		(3930.4)
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		(4010)
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1.65
Larval Midgut		3930.4
Larval Hindgut		4.6
Larval Malpighian Tubules		0.8
Larval Fat Body		10.6
Larval Salivary Gland		1.9
Larval Trachea		0.85
Larval Carcass		3.275
Adult Head		1.7
Adult Eye		3.9
Adult Brain		2
Adult Thoracic-Abdominal Ganglion		2.1
Adult Crop		2.2
Adult Midgut		4010
Adult Hindgut		2
Adult Malpighian Tubules		3.5
Adult Fat Body		2.8
Adult Salivary Gland		3.2
Adult Heart		0.35
Adult VirginFemale Spermatheca		4.8
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		0.7
Adult Testis		15.4
Adult Male Accessory Gland		4
Adult Carcass		9.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	1.7
NA	Eye	3.9
NA	Brain	2
1.65	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	2.1
NA	Crop	2.2
3930.4	Midgut	4010
4.6	Hindgut	2
0.8	Malpighian Tubules	3.5
no informative data	Fat Body	2.8
1.9	Salivary Gland	3.2
NA	Heart	0.35
0.85	Trachea	NA
NA	VirginFemale Spermatheca	4.8
NA	InseminatedFemale Spermatheca	5.4
NA	Ovary	0.7
NA	Testis	15.4
NA	Male Accessory Gland	4
3.275	Carcass	9.4

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		944
digestive system, 4-day adult		792
digestive system, 20-day adult		504
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(105)
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		(80)
digestive system, 1-day adult		(944)
digestive system, 4-day adult		(792)
digestive system, 20-day adult		(504)
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		(34)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		(944)
digestive system, 4-day adult		(792)
digestive system, 20-day adult		(504)
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		944
digestive system, 4-day adult		792
digestive system, 20-day adult		504
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		944
digestive system, 4-day adult		792
digestive system, 20-day adult		504
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(105)
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		(80)
digestive system, 1-day adult		(944)
digestive system, 4-day adult		(792)
digestive system, 20-day adult		(504)
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		(34)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		(944)
digestive system, 4-day adult		(792)
digestive system, 20-day adult		(504)
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		105
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		80
digestive system, 1-day adult		944
digestive system, 4-day adult		792
digestive system, 20-day adult		504
fat body, larvae L3 wandering		1
fat body, white prepupae		1
fat body, pupae P8		2
carcass, larvae L3 wandering		1
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		4
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		23
accessory gland, mated 4-day male		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		113
embryo 22-24hr		96
larva L1		190
larva L2		245
larva L3 12hr old		210
larva L3 puffstage 1-2		450
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		252
adult male 05day		147
adult male 30day		57
adult female 01day		302
adult female 05day		163
adult female 30day		88
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		(113)
embryo 22-24hr		(96)
larva L1		(190)
larva L2		(245)
larva L3 12hr old		(210)
larva L3 puffstage 1-2		(450)
larva L3 puffstage 3-6		(97)
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		(252)
adult male 05day		(147)
adult male 30day		(57)
adult female 01day		(302)
adult female 05day		(163)
adult female 30day		(88)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		(113)
embryo 22-24hr		96
larva L1		(190)
larva L2		(245)
larva L3 12hr old		(210)
larva L3 puffstage 1-2		(450)
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		(252)
adult male 05day		(147)
adult male 30day		57
adult female 01day		(302)
adult female 05day		(163)
adult female 30day		88
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		113
embryo 22-24hr		96
larva L1		190
larva L2		245
larva L3 12hr old		210
larva L3 puffstage 1-2		450
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		252
adult male 05day		147
adult male 30day		57
adult female 01day		302
adult female 05day		163
adult female 30day		88
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		113
embryo 22-24hr		96
larva L1		190
larva L2		245
larva L3 12hr old		210
larva L3 puffstage 1-2		450
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		252
adult male 05day		147
adult male 30day		57
adult female 01day		302
adult female 05day		163
adult female 30day		88
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		(113)
embryo 22-24hr		(96)
larva L1		(190)
larva L2		(245)
larva L3 12hr old		(210)
larva L3 puffstage 1-2		(450)
larva L3 puffstage 3-6		(97)
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		(252)
adult male 05day		(147)
adult male 30day		(57)
adult female 01day		(302)
adult female 05day		(163)
adult female 30day		(88)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		113
embryo 22-24hr		96
larva L1		(190)
larva L2		(245)
larva L3 12hr old		(210)
larva L3 puffstage 1-2		(450)
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		(252)
adult male 05day		(147)
adult male 30day		57
adult female 01day		(302)
adult female 05day		(163)
adult female 30day		88
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		4
embryo 20-22hr		113
embryo 22-24hr		96
larva L1		190
larva L2		245
larva L3 12hr old		210
larva L3 puffstage 1-2		450
larva L3 puffstage 3-6		97
larva L3 puffstage 7-9		13
white prepupae new		1
white prepupae 12hr		1
white prepupae 24hr		0
pupae 2d postWPP		1
pupae 3d postWPP		0
pupae 4d postWPP		1
adult male 01day		252
adult male 05day		147
adult male 30day		57
adult female 01day		302
adult female 05day		163
adult female 30day		88
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		217
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		147
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		183
Ethanol 10% 3 hrs, larvae L3		117
Caffeine 1.5 mg/ml 4 hrs, larvae L3		181
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		244
Rotenone 8 μg 12 hrs, larvae L3		279
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		(90)
Cadmium 50 mM 6 hrs, larvae L3		(217)
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		(147)
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		(79)
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		(59)
Zinc 4.5 mM 48 hrs, 4-day adult		(28)
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		(183)
Ethanol 10% 3 hrs, larvae L3		(117)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(181)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		(37)
Rotenone 2 μg 12 hrs, larvae L3		(244)
Rotenone 8 μg 12 hrs, larvae L3		(279)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		(217)
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		(147)
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		(183)
Ethanol 10% 3 hrs, larvae L3		(117)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(181)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		(244)
Rotenone 8 μg 12 hrs, larvae L3		(279)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		217
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		147
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		183
Ethanol 10% 3 hrs, larvae L3		117
Caffeine 1.5 mg/ml 4 hrs, larvae L3		181
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		244
Rotenone 8 μg 12 hrs, larvae L3		279
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		217
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		147
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		183
Ethanol 10% 3 hrs, larvae L3		117
Caffeine 1.5 mg/ml 4 hrs, larvae L3		181
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		244
Rotenone 8 μg 12 hrs, larvae L3		279
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		(90)
Cadmium 50 mM 6 hrs, larvae L3		(217)
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		(147)
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		(79)
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		(59)
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		(183)
Ethanol 10% 3 hrs, larvae L3		(117)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(181)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		(37)
Rotenone 2 μg 12 hrs, larvae L3		(244)
Rotenone 8 μg 12 hrs, larvae L3		(279)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		(217)
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		(147)
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		(183)
Ethanol 10% 3 hrs, larvae L3		117
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(181)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		(244)
Rotenone 8 μg 12 hrs, larvae L3		(279)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		12
cold shock, 4-day adult		11
heat shock, 4-day adult		90
Cadmium 50 mM 6 hrs, larvae L3		217
Cadmium 50 mM 12 hrs, larvae L3		22
Cadmium 50 mM 48 hrs, 4-day adult		147
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		79
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		59
Zinc 4.5 mM 48 hrs, 4-day adult		28
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		183
Ethanol 10% 3 hrs, larvae L3		117
Caffeine 1.5 mg/ml 4 hrs, larvae L3		181
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		10
Paraquat 10 mM 48 hrs, 4-day adult		37
Rotenone 2 μg 12 hrs, larvae L3		244
Rotenone 8 μg 12 hrs, larvae L3		279
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

RE08556

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0032069

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG9468-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG9468

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG9468^GD5106

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG9468	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG9468	Mutagen	Stocks	Known lesion
CG9468^GD5106	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG9468^KK106549	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9468^GD16979	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel7039

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD5106}

P{GD16979}

P{KK106549}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 5 terms )

Molecular Function

CV term

Evidence

References

alpha-mannosidase activity

inferred from sequence or structural similarity with UniProtKB:O09159

(FlyBase, 1992-)

carbohydrate binding

inferred from electronic annotation with InterPro:IPR011013

(FlyBase Curators et al., 2004-)

zinc ion binding

inferred from electronic annotation with InterPro:IPR015341

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

mannose metabolic process

inferred from electronic annotation with InterPro:IPR011682

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

lysosome

inferred from sequence or structural similarity with UniProtKB:O09159

(FlyBase, 1992-)

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG9468 - CG9466

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG9468 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

60322

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0032069

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

34206

Orthologs

OrthoDB Orthologs (71) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG68WCMF

Dipteran inclusive ortholog search

EOG6H1B3T

Insect inclusive ortholog search

EOG6W3RH1

Arthropod inclusive ortholog search

EOG6XD260

Metazoa inclusive ortholog search

EOG6TJ7KT, EOG6N3CFN

Orthologs in Drosophila Species (EOG68WCMF)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\CG9468

Drosophila melanogaster

fruit fly

Dmel\CG5322

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila simulans

Drosophila sechellia

Drosophila sechellia

Drosophila erecta

Drosophila erecta

Drosophila erecta

Drosophila yakuba

Drosophila yakuba

Drosophila yakuba

Drosophila ananassae

Drosophila ananassae

Drosophila ananassae

Drosophila ananassae

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA28078

Drosophila pseudoobscura pseudoobscura

Dpse\GA28080

Drosophila pseudoobscura pseudoobscura

Dpse\GA21810

Drosophila persimilis

Dper\GL26214

Drosophila persimilis

Dper\GL26216

Drosophila willistoni

Dwil\GK24528

Drosophila willistoni

Dwil\GK14881

Drosophila willistoni

Dwil\GK24529

Drosophila willistoni

Dwil\GK14880

Drosophila willistoni

Dwil\GK24522

Drosophila virilis

Dvir\GJ11812

Drosophila mojavensis

Dmoj\GI13451

Drosophila grimshawi

Dgri\GH16722

Orthologs in non-Drosophila Dipterans (EOG6H1B3T)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005749

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ802256

Orthologs in non-Dipteran Insects (EOG6W3RH1)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB44223

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG011999

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH21614

Atta cephalotes

Leafcutter ant

Acep\ACEP16189

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO20204

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL13198

Linepithema humile

Argentine ant

Lhum\LH17851

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB25066

Solenopsis invicta

Red fire ant

Sinv\SINV25543

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI003815

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI000918

Bombyx mori

Silkmoth

Bmor\BGIBMGA011378

Bombyx mori

Silkmoth

Bmor\BGIBMGA001728

Pediculus humanus

Human body louse

Phum\PHUM407580

Pediculus humanus

Human body louse

Phum\PHUM446310

Tribolium castaneum

Red flour beetle

Tcas\TC006453

Tribolium castaneum

Red flour beetle

Tcas\TC006455

Tribolium castaneum

Red flour beetle

Tcas\TC002467

Tribolium castaneum

Red flour beetle

Tcas\TC002465

Tribolium castaneum

Red flour beetle

Tcas\TC002466

Tribolium castaneum

Red flour beetle

Tcas\TC006456

Tribolium castaneum

Red flour beetle

Tcas\TC006454

Tribolium castaneum

Red flour beetle

Tcas\TC002464

Orthologs in non-Insect Arthropods (EOG6XD260)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_207420

Daphnia pulex

Water flea

Dpux\JGI_V11_324591

Daphnia pulex

Water flea

Dpux\Ilkap

Daphnia pulex

Water flea

Dpux\RPB2

Daphnia pulex

Water flea

Dpux\JGI_V11_315529

Daphnia pulex

Water flea

Dpux\JGI_V11_337859

Ixodes scapularis

Deer tick

Isca\ISCW017358

Ixodes scapularis

Deer tick

Isca\ISCW012835

Orthologs in non-Arthropod Metazoa (EOG6TJ7KT, EOG6N3CFN)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\aman-1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_006585gn

Danio rerio

Zebrafish

Drer\zgc:110815

Xenopus tropicalis

Western clawed frog

Xtro\man2b1

Mus musculus

House mouse

Mmus\Man2b1

Rattus norvegicus

Norway rat

Rnor\Man2b1

Homo sapiens

Human

Hsap\MAN2B1

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\MAN2B1

AAA Orthologs (0) based on analysis using Dmel annotation version 4.3

No orthologs identified

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

VDRC

v104268

P{KK106549}VIE-260B

v15590

w¹¹¹⁸; P{GD5106}v15590

v15591

w¹¹¹⁸; P{GD5106}v15591

Genomic Clones ( 1 )

BACR01O16

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 22 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE08556

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0032069

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

34206

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_135409

RefSeq (Proteins)

•

NP_609253

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

34206

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Glycoside hydrolase family 38, N-terminal domain (IPR000602)

Galactose mutarotase-like domain (IPR011013)

Glycosyl hydrolase family 38, C-terminal (IPR011682)

Glycoside hydrolase/deacetylase, beta/alpha-barrel (IPR011330)

Glycosyl hydrolase, family 13, all-beta (IPR013780)

Glycoside hydrolase, family 38, central domain (IPR015341)

Glycoside hydrolase 38/57, N-terminal domain (IPR027291)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

RE08556

Linkouts

BioGRID - A database of protein and genetic interactions

•

60322

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0032069

DRSC - Results from RNAi screens.

•

FBgn0032069

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0032069

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG9468-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0032069

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

34206

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

34206

modMine - Data generated by the modENCODE project.

•

FBgn0032069

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG9468

(Pedersen et al., 2010, Li et al., 2009, Buch et al., 2008, Keleman et al., 2009.8.5, Tomancak et al., 2007, Fernández-Ayala et al., 2010, Friedman et al., 2011, Sieber and Thummel, 2009)

Name Synonym

Secondary FlyBase IDs

References ( 28 )

Generate a list of

All references relating to this gene ( 28 )

List References by type

Recent research papers ( 2 )

Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134: Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342]
Friedman et al., 2011, Sci. Signal. 4(196): rs10: Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. [FBrf0216513]

Show all research papers ...