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Gene Dmel\Tsp29Fa

General Information
Symbol	Dmel\Tsp29Fa	Species	D. melanogaster
Name	Tetraspanin 29Fa	Annotation symbol	CG9494
Feature type	protein_coding_gene	FlyBase ID	FBgn0032074
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	29F4-29F4	Sequence location	2L:8,933,964..8,936,096 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Tetraspanin 29Fa is referred to in FlyBase by the symbol Dmel\Tsp29Fa (CG9494, FBgn0032074). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin, conserved site; Tetraspanin, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, inseminated spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: virgin spermatheca. Comments on Affy2 ProbeSet: ProbeSet 1625439_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Tsp29Fa. Gene sequence location is 2L:8933964..8936096.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References FlyBase Curators, 2010-, Gene Ontology (GO) annotation review.
FB2012_01	Sequence features HFA03232 BKN23064
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29F4-29F4   Limits computationally determined from genome sequence between P{lacW}l(2)k04003k04003 and P{PZ}tai01351
Experimentally Determined Cytological Location
Cytogenetic map Notes References 29F-29F     (Todres, 2000.6.1)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tsp29Fa for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tsp29Fa-RA FBtr0079754  NM_078791   963   248 Tsp29Fa-RB FBtr0300289  NM_001169444   1039   248
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tsp29Fa-PA   FBpp0079355   26.6   248   5.62     NP_523515   AAF52719 Tsp29Fa-PB   FBpp0289517   26.6   248   5.62     NP_001162915   ACZ94205
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tetraspanin (IPR018499) Tetraspanin, conserved site (IPR018503) Tetraspanin, subgroup (IPR000301) Tetraspanin, EC2 domain (IPR008952)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52719   AE014134 ACZ94205   AF274011 AAF90137   AI257629   AY071356 AAL48978   BI169290   BI242125   BI356415   BI482923   CA804393   CA806104   CK657026   CO180139   CO266065   CO266216   CO282340   CO303726   CO309382   CO318568   CO339069   EC072971   EC075875   EC078373   EC084455   EC084973   EC087782   EC254256   EL886701   GH758828   GH792582   GH802369   GH817627   GH822239   GH829381   GH829875   GH836767   GH844043   GH910357   GH910617   GH923577   GH930083   GH933333
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VLH1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032074    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032074 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032074 expression level Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2    13521 larva L3 puffstage 3-6    15499 larva L3 puffstage 7-9    14703 white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr  (115) embryo 12-14hr  (292) embryo 14-16hr  (1933) embryo 16-18hr  (4838) embryo 18-20hr  (5742) embryo 20-22hr  (5926) embryo 22-24hr  (6743) larva L1  (6118) larva L2  (6982) larva L3 12hr old  (5174) larva L3 puffstage 1-2  (13521) larva L3 puffstage 3-6  (15499) larva L3 puffstage 7-9  (14703) white prepupae new  (5486) white prepupae 12hr  (1067) white prepupae 24hr  (115) pupae 2d postWPP  (187) pupae 3d postWPP  (722) pupae 4d postWPP  (1280) adult male 01day  (3049) adult male 05day  (3632) adult male 30day  (3503) adult female 01day  (3648) adult female 05day  (2566) adult female 30day  (3016) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr  (1933) embryo 16-18hr  (4838) embryo 18-20hr  (5742) embryo 20-22hr  (5926) embryo 22-24hr  (6743) larva L1  (6118) larva L2  (6982) larva L3 12hr old  (5174) larva L3 puffstage 1-2  (13521) larva L3 puffstage 3-6  (15499) larva L3 puffstage 7-9  (14703) white prepupae new  (5486) white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day  (3049) adult male 05day  (3632) adult male 30day  (3503) adult female 01day  (3648) adult female 05day  (2566) adult female 30day  (3016) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2  (13521) larva L3 puffstage 3-6  (15499) larva L3 puffstage 7-9  (14703) white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2    13521 larva L3 puffstage 3-6    15499 larva L3 puffstage 7-9    14703 white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032074 expression level Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2    13521 larva L3 puffstage 3-6    15499 larva L3 puffstage 7-9    14703 white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr  115 embryo 12-14hr  (292) embryo 14-16hr  (1933) embryo 16-18hr  (4838) embryo 18-20hr  (5742) embryo 20-22hr  (5926) embryo 22-24hr  (6743) larva L1  (6118) larva L2  (6982) larva L3 12hr old  (5174) larva L3 puffstage 1-2  (13521) larva L3 puffstage 3-6  (15499) larva L3 puffstage 7-9  (14703) white prepupae new  (5486) white prepupae 12hr  (1067) white prepupae 24hr  115 pupae 2d postWPP  (187) pupae 3d postWPP  (722) pupae 4d postWPP  (1280) adult male 01day  (3049) adult male 05day  (3632) adult male 30day  (3503) adult female 01day  (3648) adult female 05day  (2566) adult female 30day  (3016) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr  1933 embryo 16-18hr  (4838) embryo 18-20hr  (5742) embryo 20-22hr  (5926) embryo 22-24hr  (6743) larva L1  (6118) larva L2  (6982) larva L3 12hr old  (5174) larva L3 puffstage 1-2  (13521) larva L3 puffstage 3-6  (15499) larva L3 puffstage 7-9  (14703) white prepupae new  (5486) white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day  (3049) adult male 05day  (3632) adult male 30day  (3503) adult female 01day  (3648) adult female 05day  (2566) adult female 30day  (3016) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2  13521 larva L3 puffstage 3-6  15499 larva L3 puffstage 7-9  14703 white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    21 embryo 02-04hr    18 embryo 04-06hr    26 embryo 06-08hr    37 embryo 08-10hr    74 embryo 10-12hr    115 embryo 12-14hr    292 embryo 14-16hr    1933 embryo 16-18hr    4838 embryo 18-20hr    5742 embryo 20-22hr    5926 embryo 22-24hr    6743 larva L1    6118 larva L2    6982 larva L3 12hr old    5174 larva L3 puffstage 1-2    13521 larva L3 puffstage 3-6    15499 larva L3 puffstage 7-9    14703 white prepupae new    5486 white prepupae 12hr    1067 white prepupae 24hr    115 pupae 2d postWPP    187 pupae 3d postWPP    722 pupae 4d postWPP    1280 adult male 01day    3049 adult male 05day    3632 adult male 30day    3503 adult female 01day    3648 adult female 05day    2566 adult female 30day    3016 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032074    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032074 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, inseminated spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: virgin spermatheca. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032074 expression level Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut    4660.1 Larval Hindgut    888.3 Larval Malpighian Tubules    1464.7 Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut    4176.8 Adult Hindgut    1643.8 Adult Malpighian Tubules    1728 Adult Fat Body no informative data Adult Salivary Gland    1335.2 Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut  (4660.1) Larval Hindgut  (888.3) Larval Malpighian Tubules  (1464.7) Larval Fat Body    7.8 Larval Salivary Gland  (554.2) Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut  (4176.8) Adult Hindgut  (1643.8) Adult Malpighian Tubules  (1728) Adult Fat Body no informative data Adult Salivary Gland  (1335.2) Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca  524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut  (4660.1) Larval Hindgut    888.3 Larval Malpighian Tubules  (1464.7) Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut  (4176.8) Adult Hindgut  (1643.8) Adult Malpighian Tubules  (1728) Adult Fat Body no informative data Adult Salivary Gland  (1335.2) Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut    4660.1 Larval Hindgut    888.3 Larval Malpighian Tubules    1464.7 Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut    4176.8 Adult Hindgut    1643.8 Adult Malpighian Tubules    1728 Adult Fat Body no informative data Adult Salivary Gland    1335.2 Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032074 expression level Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut    4660.1 Larval Hindgut    888.3 Larval Malpighian Tubules    1464.7 Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut    4176.8 Adult Hindgut    1643.8 Adult Malpighian Tubules    1728 Adult Fat Body no informative data Adult Salivary Gland    1335.2 Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut  (4660.1) Larval Hindgut  (888.3) Larval Malpighian Tubules  (1464.7) Larval Fat Body    7.8 Larval Salivary Gland  554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut  (4176.8) Adult Hindgut  (1643.8) Adult Malpighian Tubules  (1728) Adult Fat Body no informative data Adult Salivary Gland  (1335.2) Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca  524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut  (4660.1) Larval Hindgut    888.3 Larval Malpighian Tubules  1464.7 Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut  (4176.8) Adult Hindgut  1643.8 Adult Malpighian Tubules  (1728) Adult Fat Body no informative data Adult Salivary Gland  1335.2 Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    6.125 Larval Midgut    4660.1 Larval Hindgut    888.3 Larval Malpighian Tubules    1464.7 Larval Fat Body    7.8 Larval Salivary Gland    554.2 Larval Trachea    7.75 Larval Carcass    9.6 Adult Head    56.8 Adult Eye no informative data Adult Brain    5.6 Adult Thoracic-Abdominal Ganglion    8.4 Adult Crop    24.2 Adult Midgut    4176.8 Adult Hindgut    1643.8 Adult Malpighian Tubules    1728 Adult Fat Body no informative data Adult Salivary Gland    1335.2 Adult Heart    8.45 Adult VirginFemale Spermatheca    481.6 Adult InseminatedFemale Spermatheca    524 Adult Ovary    1.8 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    56.8   NA  Eye    no informative data   NA  Brain    5.6   6.125  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    8.4   NA  Crop    24.2   4660.1  Midgut    4176.8   888.3  Hindgut    1643.8   1464.7  Malpighian Tubules    1728   7.8  Fat Body    no informative data   554.2  Salivary Gland    1335.2   NA  Heart    8.45   7.75  Trachea    NA   NA  VirginFemale Spermatheca    481.6   NA  InseminatedFemale Spermatheca    524   NA  Ovary    1.8   NA  Testis    no informative data   NA  Male Accessory Gland    no informative data   9.6  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032074 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9494-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Tsp29Fa Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Tsp29FaGD1017 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Tsp29Fa Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tsp29Fa Class Mutagen Stocks Known lesion Tsp29FaGD1017 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Tsp29FaKK102968 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7040 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1017} NA P{KK102968} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a biological process or molecular function term for this gene. (Based on a review of available data on: 2011-06-30)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000301, InterPro:IPR008952, InterPro:IPR018499, InterPro:IPR018503 (FlyBase Curators et al., 2004-) inferred from sequence model (Fradkin et al., 2002) inferred from sequence or structural similarity (Todres et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tsp29Fa allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0032074
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15553 Dere\GG25314 Dgri\GH13873 Dmoj\GI17425 Dper\GL25578 Dpse\GA21830 Dsec\GM17261 Dvir\GJ18360 Dwil\GK24538 Dyak\GE18806
Curated drosophilid orthologs	Dpse\GA21830
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL003210-PA Aedes aegypti (mosquito) AGAP009651-PA Anopheles gambiae (mosquito) XP_392592.2 Apis mellifera (honey bee) XP_001948078.1 Acyrthosiphon pisum (pea aphid) 24689 Batrachochytrium dendrobatidis (chytrid fungus) 124708 Branchiostoma floridae (lancelet) BGIBMGA002919-PA Bombyx mori (silk worm) ENSBTAP00000015829 Bos taurus (bovine) ENSCAFP00000000096 Canis familiaris (dog) ENSCINP00000025966 Ciona intestinalis (sea squirt) CPIJ010984 Culex pipens (mosquito) ENSCPOP00000008209 Cavia porcellus (guinea pig) 151708 Capitella spl (polychaete worm) DDB0191510 Dictyostelium discoideum (amoeba) DDB0252563 Dictyostelium discoideum (amoeba) ENSECAP00000017837 Equus caballus (horse) 185019 Hypsipyla robusta (cedar shoot borer) ENSP00000257857 Homo sapiens (human) ENSMMUP00000017381 Macaca mulatta (rhesus monkey) ENSMUSP00000100862 Mus musculus (house mouse) XP_001605056.1 Nasonia vitripennis (wasp) ENSOANP00000022489 Ornithorynchus anatinus (platypus) ENSORLP00000019088 Oryzias latipes (japanese killifish) PHUM009696-PA Pediculus humanus (human body louse) ENSPPYP00000005275 Pongo pygmaeus (orangutan) ENSPTRP00000008613 Pan troglodytes (chimpanzee) ENSRNOP00000010180 Rattus norvegicus (norway rat) XP_800780.2 Strongylocentrotus purpuratus (purple sea urchin) 63102 Trichoplax adhaerens (metazoa) XP_971361.1 Tribolium castaneum (red flour beetle) ENSTRUP00000039740 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17281 NV13557 LH22372 FBgn0236192 FBgn0226498 FBgn0205519 FBgn0172172 FBgn0081815 FBgn0163162 FBgn0140169 FBgn0121349 FBgn0117435 FBgn0092578 CPIJ010984 BGIBMGA002919 ACYPI002976 GB13074 AGAP009651 AAEL003210 GLEAN_12380 GLEAN_12379
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v105839 P{KK102968}VIE-260B v44876 w1118; P{GD1017}v44876 v44877 w1118; P{GD1017}v44877
Genomic Clones ( 2 )
	BACR01O16 BACR05B09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 38 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE39366
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP06047 LP22967 RE10424 RE42557 RE65732
Other clones	34585 34977 44079 83486 102890 173570 214477.12 EC01021 EK144834 EK145450 EK160248 EK217456 EK242630 EK272847 EP00731 ESG012a.E21_B04 ESG0113b.B21.1_G07 IP17924 RP003165266 RP003178996 RP003195870 RP003252675 RP003306743 RP003342494 RP003342765 RP003352347 RP003448982 RP003470495 RP003501341 RP003521019 RP003599610 RP003665872
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032074 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34211
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Tsp29Fa CG9494 (FlyBase, 1996-)
Source for database merge of
Additional comments	Source for identity of Tsp29Fa CG9494 was sequence comparison (date:000815). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078791 NM_001169444 RefSeq (Proteins) • NP_523515 NP_001162915 DDBJ / EMBL / GenBank • AAF52719 AAF90137 AAL48978 ACZ94205 AF274011 AI257629 AY071356 BI242125 Entrez Gene - A searchable database of RefSeq genes. • 34211 UniProtKB/TrEMBL • Q9VLH1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tetraspanin (IPR018499) Tetraspanin, conserved site (IPR018503) Tetraspanin, subgroup (IPR000301) Tetraspanin, EC2 domain (IPR008952)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0032074 DRSC - Results from RNAi screens. • FBgn0032074 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032074 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9494-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032074 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34211 InParanoid A subset of ortholog calls from InParanoid. • AAEL003210-PA Aedes aegypti (mosquito) AGAP009651-PA Anopheles gambiae (mosquito) XP_392592.2 Apis mellifera (honey bee) XP_001948078.1 Acyrthosiphon pisum (pea aphid) 24689 Batrachochytrium dendrobatidis (chytrid fungus) 124708 Branchiostoma floridae (lancelet) BGIBMGA002919-PA Bombyx mori (silk worm) ENSBTAP00000015829 Bos taurus (bovine) ENSCAFP00000000096 Canis familiaris (dog) ENSCINP00000025966 Ciona intestinalis (sea squirt) CPIJ010984 Culex pipens (mosquito) ENSCPOP00000008209 Cavia porcellus (guinea pig) 151708 Capitella spl (polychaete worm) DDB0191510 Dictyostelium discoideum (amoeba) DDB0252563 Dictyostelium discoideum (amoeba) ENSECAP00000017837 Equus caballus (horse) 185019 Hypsipyla robusta (cedar shoot borer) ENSP00000257857 Homo sapiens (human) ENSMMUP00000017381 Macaca mulatta (rhesus monkey) ENSMUSP00000100862 Mus musculus (house mouse) XP_001605056.1 Nasonia vitripennis (wasp) ENSOANP00000022489 Ornithorynchus anatinus (platypus) ENSORLP00000019088 Oryzias latipes (japanese killifish) PHUM009696-PA Pediculus humanus (human body louse) ENSPPYP00000005275 Pongo pygmaeus (orangutan) ENSPTRP00000008613 Pan troglodytes (chimpanzee) ENSRNOP00000010180 Rattus norvegicus (norway rat) XP_800780.2 Strongylocentrotus purpuratus (purple sea urchin) 63102 Trichoplax adhaerens (metazoa) XP_971361.1 Tribolium castaneum (red flour beetle) ENSTRUP00000039740 Takifugu rubripes (pufferfish Takifugu) modMine - Data generated by the modENCODE project. • FBgn0032074 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17281 NV13557 LH22372 FBgn0236192 FBgn0226498 FBgn0205519 FBgn0172172 FBgn0081815 FBgn0163162 FBgn0140169 FBgn0121349 FBgn0117435 FBgn0092578 CPIJ010984 BGIBMGA002919 ACYPI002976 GB13074 AGAP009651 AAEL003210 GLEAN_12380 GLEAN_12379
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG9494 (Fradkin et al., 2002, Todres et al., 2000, Keleman et al., 2009.8.5) Dm.Tsp29Fa (Todres et al., 2000) Tsp29Fa (Senger et al., 2006, Okumura et al., 2007)
Name Synonym	Tetraspanin 29Fa (Todres, 2000.6.1)
Secondary FlyBase IDs
References ( 18 )
Research paper	Okumura et al., 2007, Gene Expression Patterns 7(1-2): 178--186 GATAe-dependent and -independent expressions of genes in the differentiated endodermal midgut of Drosophila. [FBrf0194340] Senger et al., 2006, Proc. Natl. Acad. Sci. USA 103(43): 15957--15962 GATA factors participate in tissue-specific immune responses in Drosophila larvae. [FBrf0195200] Fradkin et al., 2002, Proc. Natl. Acad. Sci. USA 99(21): 13663--13668 Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. [FBrf0152316] Todres et al., 2000, Insect Molec. Biol. 9(6): 581--590 The tetraspanin superfamily in insects. [FBrf0132356]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Robertson, 2000.4.13, FlyBase error report for CG9494 on Thu Apr 13 10:30:31 2000. FlyBase error report for CG9494 on Thu Apr 13 10:30:31 2000. [FBrf0128953]
FlyBase analysis	FlyBase Curators, 2010-, Gene Ontology (GO) annotation review. Gene Ontology (GO) annotation review. [FBrf0216433] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
DNA/RNA sequence record	Todres, 2000.6.1, GenBank/EMBL/DDBJ: AF274011 Drosophila melanogaster tetraspanin 29Fa mRNA, complete cds. [FBrf0130962]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]