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Gene Dmel\CG5734

General Information
Symbol	Dmel\CG5734	Species	D. melanogaster
Name		Annotation symbol	CG5734
Feature type	protein_coding_gene	FlyBase ID	FBgn0032191
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	31B1-31B1	Sequence location	2L:10,204,757..10,206,961 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5734 (FBgn0032191). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: phosphatidylinositol binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cell communication. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phox homologous domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, larval midgut, larval salivary gland, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623989_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5734. Gene sequence location is 2L:10204757..10206961.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN28841 HFA02884
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 31B1-31B1   Limits computationally determined from genome sequence between P{lacW}l(2)k06324k06324 and P{lacW}me31Bk06607
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5734 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5734-RA FBtr0079960  NM_135509   2205   490
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5734-PA   FBpp0079550   55.3   490   7.46     NP_609353   AAF52870
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phox homologous domain (IPR001683)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202638   AA390868   AA391511   AA440468   AA990829   AE014134 AAF52870   AI134597   AI135707   AI260420   AI296049   AI533479   AI541791   AI542978   AW942346   AY061191 AAL28739   BF489129   BF505027   BG637091   BG640692   BI162655   BI162656   BI169513   BI214645   BI358111   BI371090   BI567626   BI580726   BI586151   BI589089   BI611730   BI624398   BI638400   BI640275   BP549472   BP549473   BQ102735   CK657028   CK657058   CK657981   CO153249   CO156994   CO263133   CO279683   CO283106   CO333506   EC059245   EC085089   EC090770   EC217317   EC221131   EC231236   EC231238   EC241888   EC263097   EC264525   EV579912   GH752770   GH754205   GH758100   GH759410   GH770709   GH773173   GH774047   GH780405   GH782964   GH784187   GH785715   GH791185   GH793232   GH795823   GH797670   GH800502   GH803925   GH805528   GH814364   GH814743   GH818663   GH818937   GH820058   GH824117   GH826594   GH827576   GH829427   GH830637   GH831688   GH837474   GH844071   GH844784   GH845767   GH845801   GH845965   GH846570   GH851276   GH851488   GH854840   GH860456   GH860589   GH861561   GH862117   GH866712   GH869929   GH871319   GH879560   GH881640   GH881785   GH882772   GH885596   GH887426   GH889223   GH890633   GH896183   GH897850   GH902693   GH908198   GH909889   GH914204   GH916661   GH921007   GH921112   GH923487   GH926090   GH928814   GH931670   GH933125   GH936400   GH938694   GH938856   GH939047   GH939248   GH940143
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VL28
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032191    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032191 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032191 expression level Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5361) embryo 02-04hr  (1482) embryo 04-06hr  (2325) embryo 06-08hr  (2247) embryo 08-10hr  (1716) embryo 10-12hr  (1894) embryo 12-14hr  (939) embryo 14-16hr  (1329) embryo 16-18hr  (1096) embryo 18-20hr  (1085) embryo 20-22hr  (807) embryo 22-24hr  (777) larva L1  (1030) larva L2  (992) larva L3 12hr old  (1222) larva L3 puffstage 1-2  (1280) larva L3 puffstage 3-6  (1857) larva L3 puffstage 7-9  (1735) white prepupae new  (1437) white prepupae 12hr  (1538) white prepupae 24hr  (1426) pupae 2d postWPP  (1229) pupae 3d postWPP  (931) pupae 4d postWPP  (959) adult male 01day  (1030) adult male 05day  (1127) adult male 30day  (1371) adult female 01day  (2470) adult female 05day  (3232) adult female 30day  (3600) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5361) embryo 02-04hr  1482 embryo 04-06hr  (2325) embryo 06-08hr  (2247) embryo 08-10hr  (1716) embryo 10-12hr  (1894) embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6  (1857) larva L3 puffstage 7-9  (1735) white prepupae new  1437 white prepupae 12hr  (1538) white prepupae 24hr  1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day  (2470) adult female 05day  (3232) adult female 30day  (3600) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032191 expression level Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5361) embryo 02-04hr  (1482) embryo 04-06hr  (2325) embryo 06-08hr  (2247) embryo 08-10hr  (1716) embryo 10-12hr  (1894) embryo 12-14hr  (939) embryo 14-16hr  (1329) embryo 16-18hr  (1096) embryo 18-20hr  (1085) embryo 20-22hr  (807) embryo 22-24hr  (777) larva L1  (1030) larva L2  (992) larva L3 12hr old  (1222) larva L3 puffstage 1-2  (1280) larva L3 puffstage 3-6  (1857) larva L3 puffstage 7-9  (1735) white prepupae new  (1437) white prepupae 12hr  (1538) white prepupae 24hr  (1426) pupae 2d postWPP  (1229) pupae 3d postWPP  (931) pupae 4d postWPP  (959) adult male 01day  (1030) adult male 05day  (1127) adult male 30day  (1371) adult female 01day  (2470) adult female 05day  (3232) adult female 30day  (3600) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5361) embryo 02-04hr  1482 embryo 04-06hr  2325 embryo 06-08hr  2247 embryo 08-10hr  1716 embryo 10-12hr  1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6  1857 larva L3 puffstage 7-9  1735 white prepupae new  1437 white prepupae 12hr  1538 white prepupae 24hr  1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day  2470 adult female 05day  (3232) adult female 30day  (3600) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5361 embryo 02-04hr    1482 embryo 04-06hr    2325 embryo 06-08hr    2247 embryo 08-10hr    1716 embryo 10-12hr    1894 embryo 12-14hr    939 embryo 14-16hr    1329 embryo 16-18hr    1096 embryo 18-20hr    1085 embryo 20-22hr    807 embryo 22-24hr    777 larva L1    1030 larva L2    992 larva L3 12hr old    1222 larva L3 puffstage 1-2    1280 larva L3 puffstage 3-6    1857 larva L3 puffstage 7-9    1735 white prepupae new    1437 white prepupae 12hr    1538 white prepupae 24hr    1426 pupae 2d postWPP    1229 pupae 3d postWPP    931 pupae 4d postWPP    959 adult male 01day    1030 adult male 05day    1127 adult male 30day    1371 adult female 01day    2470 adult female 05day    3232 adult female 30day    3600 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032191    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032191 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, larval midgut, larval salivary gland, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032191 expression level Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut  (580.2) Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland  500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye  (591.85) Adult Brain  (542.2) Adult Thoracic-Abdominal Ganglion  (658.5) Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary  534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032191 expression level Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut  580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland  500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye  591.85 Adult Brain  542.2 Adult Thoracic-Abdominal Ganglion  658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary  534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    422.65 Larval Midgut    580.2 Larval Hindgut    418.2 Larval Malpighian Tubules    332.3 Larval Fat Body    366.3 Larval Salivary Gland    500.8 Larval Trachea    361.25 Larval Carcass    276.85 Adult Head    373.7 Adult Eye    591.85 Adult Brain    542.2 Adult Thoracic-Abdominal Ganglion    658.5 Adult Crop    305 Adult Midgut    218.8 Adult Hindgut    209 Adult Malpighian Tubules    309.6 Adult Fat Body    341.1 Adult Salivary Gland    204.9 Adult Heart    310.775 Adult VirginFemale Spermatheca    388.1 Adult InseminatedFemale Spermatheca    451.3 Adult Ovary    534.9 Adult Testis    76.8 Adult Male Accessory Gland    219.8 Adult Carcass    197.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    373.7   NA  Eye    591.85   NA  Brain    542.2   422.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    658.5   NA  Crop    305   580.2  Midgut    218.8   418.2  Hindgut    209   332.3  Malpighian Tubules    309.6   366.3  Fat Body    341.1   500.8  Salivary Gland    204.9   NA  Heart    310.775   361.25  Trachea    NA   NA  VirginFemale Spermatheca    388.1   NA  InseminatedFemale Spermatheca    451.3   NA  Ovary    534.9   NA  Testis    76.8   NA  Male Accessory Gland    219.8   276.85  Carcass    197.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032191 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5734-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5734GD11752 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5734 Class Mutagen Stocks Known lesion CG5734EY05560 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5734 Class Mutagen Stocks Known lesion CG5734GD11752 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5734KK108841 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6026 (Ryder, 2004.4.26) Df(2L)Exel8024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11752} NA P{KK108841} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG5734EY05560 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
phosphatidylinositol binding inferred from electronic annotation with InterPro:IPR001683 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
cell communication inferred from electronic annotation with InterPro:IPR001683 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5734 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60445 DroID - A comprehensive database of gene and protein interactions. • FBgn0032191 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34354
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14132 Dere\GG23973 Dgri\GH10647 Dmoj\GI10824 Dper\GL18940 Dpse\GA19093 Dsec\GM11949 Dsim\GD22297 Dvir\GJ18286 Dwil\GK18387 Dyak\GE26362
Curated drosophilid orthologs	Dpse\GA19093
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006870-PA Aedes aegypti (mosquito) AGAP011491-PA Anopheles gambiae (mosquito) 240864 Branchiostoma floridae (lancelet) BGIBMGA003644-PA Bombyx mori (silk worm) ENSBTAP00000025998 Bos taurus (bovine) CN12036 Caenorhabditis brenneri (small nematode) CBP32109 Caenorhabditis briggsae (nematode) CE31483 Caenorhabditis elegans (worm) ENSCAFP00000007312 Canis familiaris (dog) ENSCINP00000022181 Ciona intestinalis (sea squirt) JA09092 Caenorhabditis japonica (nematode) CPIJ004644 Culex pipens (mosquito) ENSCPOP00000006980 Cavia porcellus (guinea pig) RP25620 Caenorhabditis remanei (nematode) ENSCSAVP00000010456 Ciona savignyi (sedentary tunicate) 150546 Capitella spl (polychaete worm) 317059 Daphnia pulex (daphnia) ENSDARP00000040190 Danio rerio (zebra fish) ENSECAP00000007509 Equus caballus (horse) ENSGACP00000014244 Gymnopilus aculeatus (mushroom) ENSGALP00000026600 Gallus gallus (chicken) 97472 Hypsipyla robusta (cedar shoot borer) ENSP00000233575 Homo sapiens (human) ISCW019358-PA Ixodes scapularis (deer tick) 235573 Lottia gigantea (owl limpet) 15069 Monocosta brevicollis (choanoflagellate) ENSMODP00000019547 Monodelphis domestica (gray opossum) ENSMMUP00000010866 Macaca mulatta (rhesus monkey) ENSMUSP00000031029 Mus musculus (house mouse) 230183 Nematostella vectensis (starlet anemone) XP_001604143.1 Nasonia vitripennis (wasp) ENSORLP00000020418 Oryzias latipes (japanese killifish) PHUM005629-PA Pediculus humanus (human body louse) ENSPPYP00000014016 Pongo pygmaeus (orangutan) ENSPTRP00000020212 Pan troglodytes (chimpanzee) ENSRNOP00000037890 Rattus norvegicus (norway rat) 61139 Trichoplax adhaerens (metazoa) XP_969378.2 Tribolium castaneum (red flour beetle) ENSTNIP00000019436 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000017937 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038721 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16808 NV15296 LH21458 ISCW019358 FBgn0243391 FBgn0220385 FBgn0205447 FBgn0193705 FBgn0166890 JGI_V11_317059 FBgn0079091 FBgn0156541 FBgn0133587 FBgn0118128 FBgn0116112 FBgn0091159 CPIJ004644 BGIBMGA003644 GB10004 AGAP011491 AAEL006870 PHUM616070 GLEAN_16062
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	15456 w1118; P{EPgy2}CG5734EY05560/CyO, P{sevRas1.V12}FK1
VDRC	v43798 w1118; P{GD11752}v43798
Genomic Clones ( 2 )
	BACR07H08 BACR29P12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 123 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD15323
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT07183 AT24840 GH12108 GH13552 LD02805 LD09079 LD10540 LD34741 LP04272 LP09844 LP14443 LP22969 LP23038 RE10706 RE20619 RE44782 RE57911 RE74949 RH18123 RH26001 RH30766 RH38163 RH63950 SD05316 SD06964 SD09510 SD11832 SD14950 SD20678 SD23089
Other clones	28268 45872 281930 286898 CK01.17C.C2 CK01.80A.E3 CK01.104C.G10 CK01.104C.G12 Dmel_dig_020300_0629_2751 EK087559 EK135643 EK162252 EK307130 EN01555 EN09723 FGM101F11 RE01916 RP003014201 RP003020076 RP003057066 RP003068035 RP003090683 RP003099223 RP003121421 RP003124769 RP003137195 RP003146727 RP003148665 RP003149340 RP003150029 RP003154277 RP003157882 RP003158726 RP003169291 RP003192082 RP003208720 RP003211350 RP003217525 RP003219546 RP003224722 RP003254559 RP003262780 RP003269454 RP003275554 RP003285761 RP003297346 RP003307723 RP003309876 RP003310414 RP003316643 RP003325373 RP003326484 RP003340114 RP003346229 RP003359545 RP003382044 RP003382746 RP003383633 RP003395864 RP003403606 RP003436928 RP003443703 RP003451961 RP003462110 RP003477232 RP003485444 RP003490944 RP003494370 RP003512605 RP003528860 RP003531109 RP003546348 RP003554087 RP003555372 RP003578594 RP003584262 RP003586010 RP003589546 RP003590152 RP003591441 RP003594225 RP003597691 RP003600510 RP003607471 RP003609010 RP003609500 RP003620026 RP003624861 RP003631270 RP003633494 RP003656695 UUGC0119
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032191 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34354
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135509 RefSeq (Proteins) • NP_609353 DDBJ / EMBL / GenBank • AA440468 AAF52870 AAL28739 AW942346 AY061191 Entrez Gene - A searchable database of RefSeq genes. • 34354 UniProtKB/TrEMBL • Q9VL28
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phox homologous domain (IPR001683)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60445 DroID - A comprehensive database of gene and protein interactions. • FBgn0032191 DRSC - Results from RNAi screens. • FBgn0032191 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032191 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5734-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032191 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34354 InParanoid A subset of ortholog calls from InParanoid. • AAEL006870-PA Aedes aegypti (mosquito) AGAP011491-PA Anopheles gambiae (mosquito) 240864 Branchiostoma floridae (lancelet) BGIBMGA003644-PA Bombyx mori (silk worm) ENSBTAP00000025998 Bos taurus (bovine) CN12036 Caenorhabditis brenneri (small nematode) CBP32109 Caenorhabditis briggsae (nematode) CE31483 Caenorhabditis elegans (worm) ENSCAFP00000007312 Canis familiaris (dog) ENSCINP00000022181 Ciona intestinalis (sea squirt) JA09092 Caenorhabditis japonica (nematode) CPIJ004644 Culex pipens (mosquito) ENSCPOP00000006980 Cavia porcellus (guinea pig) RP25620 Caenorhabditis remanei (nematode) ENSCSAVP00000010456 Ciona savignyi (sedentary tunicate) 150546 Capitella spl (polychaete worm) 317059 Daphnia pulex (daphnia) ENSDARP00000040190 Danio rerio (zebra fish) ENSECAP00000007509 Equus caballus (horse) ENSGACP00000014244 Gymnopilus aculeatus (mushroom) ENSGALP00000026600 Gallus gallus (chicken) 97472 Hypsipyla robusta (cedar shoot borer) ENSP00000233575 Homo sapiens (human) ISCW019358-PA Ixodes scapularis (deer tick) 235573 Lottia gigantea (owl limpet) 15069 Monocosta brevicollis (choanoflagellate) ENSMODP00000019547 Monodelphis domestica (gray opossum) ENSMMUP00000010866 Macaca mulatta (rhesus monkey) ENSMUSP00000031029 Mus musculus (house mouse) 230183 Nematostella vectensis (starlet anemone) XP_001604143.1 Nasonia vitripennis (wasp) ENSORLP00000020418 Oryzias latipes (japanese killifish) PHUM005629-PA Pediculus humanus (human body louse) ENSPPYP00000014016 Pongo pygmaeus (orangutan) ENSPTRP00000020212 Pan troglodytes (chimpanzee) ENSRNOP00000037890 Rattus norvegicus (norway rat) 61139 Trichoplax adhaerens (metazoa) XP_969378.2 Tribolium castaneum (red flour beetle) ENSTNIP00000019436 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000017937 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038721 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34354 modMine - Data generated by the modENCODE project. • FBgn0032191 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16808 NV15296 LH21458 ISCW019358 FBgn0243391 FBgn0220385 FBgn0205447 FBgn0193705 FBgn0166890 JGI_V11_317059 FBgn0079091 FBgn0156541 FBgn0133587 FBgn0118128 FBgn0116112 FBgn0091159 CPIJ004644 BGIBMGA003644 GB10004 AGAP011491 AAEL006870 PHUM616070 GLEAN_16062
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5734 (Cryderman et al., 2005, Yamamoto et al., 2009.12.23, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Cryderman et al., 2005, Dev. Dynamics 232(3): 767--774 Role of Drosophila HP1 in euchromatic gene expression. [FBrf0183904]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Yamamoto et al., 2009.12.23, Microarray analysis of Df(2L)J2. Microarray analysis of Df(2L)J2. [FBrf0209650] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]