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Gene Dmel\CG5708

General Information
Symbol	Dmel\CG5708	Species	D. melanogaster
Name		Annotation symbol	CG5708
Feature type	protein_coding_gene	FlyBase ID	FBgn0032196
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	31B1-31B1	Sequence location	2L:10,224,664..10,226,808 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5708 (FBgn0032196). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, LIM-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638516_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG5708. Gene sequence location is 2L:10224664..10226808.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 31B1-31B1   Limits computationally determined from genome sequence between P{lacW}l(2)k06324k06324 and P{lacW}me31Bk06607
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5708 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5708-RA FBtr0079955  NM_135515   1119   241 CG5708-RB FBtr0079956  NM_164893   1027   241
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5708-PA   FBpp0079545   26.6   241   8.25     NP_609359   AAF52877 CG5708-PB   FBpp0079546   26.6   241   8.25     NP_723534   AAN10724
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, LIM-type (IPR001781)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA391724   AA392918   AA438380   AE014134 AAF52877   AE014134 AAN10724   AI386492   AI402646   BG638023   BH809411   BI212794   BI227782   BI637680   BT012487   CO188399   CO263266   CO271130   CO271621   CO274205   CO283928   CO295060   CO304469   CO310999   CO311709   CO313936   CO315685   EC057348   EC067960   EC075532   EC197633   EC202155   EC203851   EC212847   EC232074   EC242666   EC242667   EC243944   EC248593   EC248594   EV576757   EV596235   GH941923   GH942758   GH944348   GH944500   GH948418   GH949162   GH950095   GH950503   GH951406   GH951548   GH951811   GH958908   GH959399   GH959570   GH962356   GH963567   GH964106   GH966126   GH967366   GH967893   GH967900   GH968053   GH968421   GH969002   GH970312   GH973292   GH974009   GH974844   GH975107   GH976431   GH977401   GH979131   GH980313   GH981441
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VL21
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary  (544.8) Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary  544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    345.875 Larval Midgut    88 Larval Hindgut    168.6 Larval Malpighian Tubules    236.8 Larval Fat Body    245.1 Larval Salivary Gland    219.8 Larval Trachea    368.475 Larval Carcass    187.175 Adult Head    253.1 Adult Eye    287.9 Adult Brain    437.1 Adult Thoracic-Abdominal Ganglion    415.4 Adult Crop    309 Adult Midgut    104.9 Adult Hindgut    216.9 Adult Malpighian Tubules    212.7 Adult Fat Body    134.3 Adult Salivary Gland    257 Adult Heart    237.475 Adult VirginFemale Spermatheca    194.8 Adult InseminatedFemale Spermatheca    210.6 Adult Ovary    544.8 Adult Testis    420.9 Adult Male Accessory Gland    243.6 Adult Carcass    154.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    253.1   NA  Eye    287.9   NA  Brain    437.1   345.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    415.4   NA  Crop    309   88  Midgut    104.9   168.6  Hindgut    216.9   236.8  Malpighian Tubules    212.7   245.1  Fat Body    134.3   219.8  Salivary Gland    257   NA  Heart    237.475   368.475  Trachea    NA   NA  VirginFemale Spermatheca    194.8   NA  InseminatedFemale Spermatheca    210.6   NA  Ovary    544.8   NA  Testis    420.9   NA  Male Accessory Gland    243.6   187.175  Carcass    154.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (33) central nervous system, larvae L3  (33) central nervous system, pupae P8  (38) head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male  (27) head, mated 20-day male  (29) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8  26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (65) ovary, mated 4-day female  (44) testis, mated 4-day male  (33) accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (33) central nervous system, larvae L3  (33) central nervous system, pupae P8  (38) head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male  27 head, mated 20-day male  29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8  26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (65) ovary, mated 4-day female  (44) testis, mated 4-day male  (33) accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    33 central nervous system, pupae P8    38 head, virgin 1-day female    18 head, virgin 4-day female    20 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    16 head, mated 20-day female    9 head, mated 1-day male    18 head, mated 4-day male    27 head, mated 20-day male    29 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    11 digestive system, 1-day adult    11 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    12 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    65 ovary, mated 4-day female    44 testis, mated 4-day male    33 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (35) embryo 02-04hr  (37) embryo 04-06hr  (34) embryo 06-08hr  26 embryo 08-10hr  (36) embryo 10-12hr  (27) embryo 12-14hr  (41) embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9  (28) white prepupae new  26 white prepupae 12hr  (28) white prepupae 24hr  (29) pupae 2d postWPP  (30) pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (35) embryo 02-04hr  (37) embryo 04-06hr  (34) embryo 06-08hr  26 embryo 08-10hr  (36) embryo 10-12hr  27 embryo 12-14hr  (41) embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9  28 white prepupae new  26 white prepupae 12hr  28 white prepupae 24hr  29 pupae 2d postWPP  30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    35 embryo 02-04hr    37 embryo 04-06hr    34 embryo 06-08hr    26 embryo 08-10hr    36 embryo 10-12hr    27 embryo 12-14hr    41 embryo 14-16hr    11 embryo 16-18hr    18 embryo 18-20hr    8 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    10 larva L2    10 larva L3 12hr old    8 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    28 white prepupae 24hr    29 pupae 2d postWPP    30 pupae 3d postWPP    20 pupae 4d postWPP    7 adult male 01day    15 adult male 05day    13 adult male 30day    11 adult female 01day    8 adult female 05day    25 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (76) Schneider line 2 Sg4  (29) embryonic 1182-4H    17 embryonic GM2  (43) embryonic Kc167  (51) embryonic S1  (38) embryonic S3  (44) leg disc CME L1    20 wing disc CME-W2  (43) wing disc ML-DmD8  (40) wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21  (57) wing disc ML-DmD32    21 haltere disc ML-DmD17-c3  (50) eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5  (40) mixed discs ML-DmD4-c1  (30) CNS ML-DmBG1-c1  (28) CNS ML-DmBG2-c2  (72) tumorous blood cells mbn2  (63) ovary fGS/OSS    24 ovary OSC  (27) ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (76) Schneider line 2 Sg4  29 embryonic 1182-4H    17 embryonic GM2  (43) embryonic Kc167  (51) embryonic S1  (38) embryonic S3  (44) leg disc CME L1    20 wing disc CME-W2  (43) wing disc ML-DmD8  (40) wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21  (57) wing disc ML-DmD32    21 haltere disc ML-DmD17-c3  (50) eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5  (40) mixed discs ML-DmD4-c1  30 CNS ML-DmBG1-c1  28 CNS ML-DmBG2-c2  (72) tumorous blood cells mbn2  (63) ovary fGS/OSS    24 ovary OSC  27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    76 Schneider line 2 Sg4    29 embryonic 1182-4H    17 embryonic GM2    43 embryonic Kc167    51 embryonic S1    38 embryonic S3    44 leg disc CME L1    20 wing disc CME-W2    43 wing disc ML-DmD8    40 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    57 wing disc ML-DmD32    21 haltere disc ML-DmD17-c3    50 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    72 tumorous blood cells mbn2    63 ovary fGS/OSS    24 ovary OSC    27 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (44) Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult  (27) Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (44) Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult  27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    5 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    44 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_05 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032196 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5708-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5708GD13501 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG5708 Class Mutagen Stocks Known lesion CG57085-SZ-3397 1 -- CG57085-SZ-3435 1 -- CG5708KG01962 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5708 Class Mutagen Stocks Known lesion CG5708GD13501 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5708NIG.5708R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6026 (Ryder, 2004.4.26) Df(2L)Exel8024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13501} NA P{NIG.5708R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS5}CG57085-SZ-3397 NA P{RS5}CG57085-SZ-3435 NA P{SUPor-P}CG5708KG01962 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
zinc ion binding inferred from electronic annotation with InterPro:IPR001781 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5708 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60452 DroID - A comprehensive database of gene and protein interactions. • FBgn0032196 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34361
Orthologs
OrthoDB Orthologs (52) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG608NVB Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6JDG44 Arthropod inclusive ortholog search EOG6FJ6S2 Metazoa inclusive ortholog search EOG6SV50Q
Orthologs in Drosophila Species (EOG608NVB)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5708     Drosophila simulans   Dsim\GD22293 Y   Drosophila sechellia   Dsec\GM11938 Y   Drosophila erecta   Dere\GG23969 Y   Drosophila yakuba   Dyak\GE26318 Y   Drosophila ananassae   Dana\GF14129 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19074 Y   Drosophila persimilis   Dper\GL19153 Y   Drosophila virilis   Dvir\GJ14918 Y   Drosophila mojavensis   Dmoj\GI18740 Y   Drosophila grimshawi   Dgri\GH13372 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6JDG44)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40663   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG009023   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15314   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10558   Atta cephalotes Leafcutter ant  Acep\ACEP16561   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20998   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12700   Linepithema humile Argentine ant  Lhum\LH16211   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25709   Bombyx mori Silkmoth  Bmor\BGIBMGA005989   Pediculus humanus Human body louse  Phum\PHUM249930   Tribolium castaneum Red flour beetle  Tcas\TC014129
Orthologs in non-Insect Arthropods (EOG6FJ6S2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\ATXN2   Ixodes scapularis Deer tick  Isca\ISCW010705
Orthologs in non-Arthropod Metazoa (EOG6SV50Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019586gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013569gn Y Danio rerio Zebrafish  Drer\lmo2 Y Danio rerio Zebrafish  Drer\si:dkey-90l8.3 Y Danio rerio Zebrafish  Drer\lmo4a Y Danio rerio Zebrafish  Drer\lmo1 Y Danio rerio Zebrafish  Drer\lmo4b Y Danio rerio Zebrafish  Drer\zgc:56628 Y Xenopus tropicalis Western clawed frog  Xtro\lmo2 Y Xenopus tropicalis Western clawed frog  Xtro\lmo4.1 Y Xenopus tropicalis Western clawed frog  Xtro\lmo4.2 Y Gallus gallus Domestic chicken  Ggal\LMO4 Y Gallus gallus Domestic chicken  Ggal\LMO1 Y Gallus gallus Domestic chicken  Ggal\LMO3 Y Gallus gallus Domestic chicken  Ggal\LMO2 Y Mus musculus House mouse  Mmus\Lmo1 Y Mus musculus House mouse  Mmus\Lmo3 Y Mus musculus House mouse  Mmus\Lmo2 Y Mus musculus House mouse  Mmus\Lmo4 Y Rattus norvegicus Norway rat  Rnor\Lmo2 Y Rattus norvegicus Norway rat  Rnor\Lmo1 Y Rattus norvegicus Norway rat  Rnor\Lmo4 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000008041 Y Homo sapiens Human  Hsap\LMO3 Y Homo sapiens Human  Hsap\ENSG00000135363 Y Homo sapiens Human  Hsap\LMO4 Y Homo sapiens Human  Hsap\LMO1 Y
Human Orthologs (4)
Gene OMIM HGNC Hsap\LMO3     Hsap\ENSG00000135363     Hsap\LMO4     Hsap\LMO1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22293 Drosophila sechellia Dsec\GM11938 Drosophila erecta Dere\GG23969 Drosophila yakuba Dyak\GE26318 Drosophila ananassae Dana\GF14129 Drosophila pseudoobscura pseudoobscura Dpse\GA19074 Drosophila persimilis Dper\GL19153 Drosophila virilis Dvir\GJ14918 Drosophila mojavensis Dmoj\GI18740 Drosophila grimshawi Dgri\GH13372
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	13926 y1 w67c23; P{SUPor-P}CG5708KG01962
Kyoto	126036 w1118; P{RS5}CG57085-SZ-3397 126060 w1118; P{RS5}CG57085-SZ-3435
VDRC	v23425 w1118; P{GD13501}v23425
Genomic Clones ( 1 )
	BACR07H08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 67 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD11652
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH16570 GH21904 LD12072 RE18033 RE25017 SD19739
Other clones	12448 77618 78103 100478 107966 157115 281938 CK01.15D.H7 CK01.105A.D6 CK01.167A.C12 CK01.169D.F12 Dmel_dig_021109_0663_0747 Dmel_neb_012270_0664_1844 EK039911 EK087947 EK102044 EK104056 EK113538 EK164821 EK208460 EK223130 EK225953 EK234330 EK244743 EK262159 LD12646 RP004019423 RP004154083 RP004161040 RP004164875 RP004172298 RP004176717 RP004191100 RP004199916 RP004231840 RP004240267 RP004242002 RP004242420 RP004253397 RP004258368 RP004261526 RP004292624 RP004319518 RP004350152 RP004355446 RP004371589 RP004384114 RP004428787 RP004446938 RP004455388 RP004460027 RP004461532 RP004461949 RP004468870 RP004483087 RP004508175 RP004513511 RP004525885 RP004556682 RP004560087
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032196 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34361
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135515 NM_164893 RefSeq (Proteins) • NP_609359 NP_723534 DDBJ / EMBL / GenBank • AA391724 AAF52877 AAN10724 BH809411 BI637680 Entrez Gene - A searchable database of RefSeq genes. • 34361 UniProtKB/TrEMBL • Q9VL21
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, LIM-type (IPR001781)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60452 DroID - A comprehensive database of gene and protein interactions. • FBgn0032196 DRSC - Results from RNAi screens. • FBgn0032196 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032196 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5708-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032196 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34361 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34361 modMine - Data generated by the modENCODE project. • FBgn0032196
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5708 (Grimberg et al., 2011, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Grimberg et al., 2011, Mol. Cell. Biol. 31(4): 897--909 Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome. [FBrf0212906] Pueyo and Couso, 2004, Development 131(13): 3107--3120 Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development. [FBrf0179395]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Lei, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126680]