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Gene Dmel\eEF1δ

General Information
Symbol	Dmel\eEF1δ	Species	D. melanogaster
Name	eEF1δ	Annotation symbol	CG4912
Feature type	protein_coding_gene	FlyBase ID	FBgn0032198
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	eEF1delta
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	31B1-31B1	Sequence location	2L:10,232,493..10,234,450 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene eEF1δ is referred to in FlyBase by the symbol Dmel\eEF1δ (CG4912, FBgn0032198). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation elongation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process: translational elongation. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Elongation factor 1 beta central acidic region, eukaryote; Translation elongation factor EF1B, beta/delta chains, conserved site; Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange; Translation elongation factor EF1B/ribosomal protein S6. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1632267_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of eEF1delta. Gene sequence location is 2L:10232493..10234450.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 31B1-31B1   Limits computationally determined from genome sequence between P{lacW}l(2)k06324k06324 and P{lacW}me31Bk06607
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\eEF1δ for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) eEF1δ-RA FBtr0079951  NM_164895   861   229 eEF1δ-RB FBtr0079952  NM_135517   942   256
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein eEF1δ-PA   FBpp0079541   25.8   229   4.36     NP_723536   AAF52880 eEF1δ-PB   FBpp0079542   28.9   256   4.49     NP_609361   AAF52879
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Translation elongation factor EF1B, beta/delta chains, conserved site (IPR001326) Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange (IPR014038) Translation elongation factor EF1B/ribosomal protein S6 (IPR014717) Elongation factor 1 beta central acidic region, eukaryote (IPR018940)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438764   AA540579   AA540580   AA802060   AA802159   AA816438   AA820743   AA951936   AE014134 AAF52879   AE014134 AAF52880   AI106729   AI258347   AI518313   AI532680   AI533450   AI541823   AW941480   AY231763   AY232133   BF504804   BG640081   BG640353   BG640358   BI162396   BI162397   BI212588   BI213202   BI213457   BI214250   BI227545   BI232122   BI239240   BI242622   BI352438   BI353271   BI354474   BI355594   BI356056   BI486000   BI564789   BI565343   BI565525   BI567647   BI568553   BI571046   BI573106   BI573122   BI582825   BI590886   BI592076   BI609269   BI609590   BI610826   BI611225   BI628417   BI634251   BI636233   BI641776   BP546740   BP547568   BP553139   BP553140   BP555343   BP555344   BP560140   BQ102749   BT003281 AAO25038   CO154311   CO155947   CO156183   CO191246   CO299877   CO336130   EC089512   EC205356   EC219008   EC247336   EC263966   EC266833   EC267557   EV575029   EV575875   EV583876   EV589712   EV595913   EV600010   GH941172   GH942803   GH942821   GH943865   GH945748   GH946308   GH947031   GH947598   GH948661   GH950295   GH950593   GH953246   GH953399   GH953642   GH953790   GH954023   GH955233   GH956548   GH958487   GH958547   GH960679   GH960745   GH961393   GH962161   GH962244   GH963081   GH964849   GH965417   GH966007   GH966287   GH969794   GH971882   GH972413   GH972717   GH973873   GH976743   GH979481   GH981449   GH981493   GH984724
UniProtKB/Swiss-Prot	Q9VL18
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) fat body/gonad primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) salivary gland body primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic anal pad   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval salivary gland   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1145.025 Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body    1417.5 Larval Salivary Gland    2572.9 Larval Trachea    1649.95 Larval Carcass    1133.875 Adult Head    1085 Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules    1043.4 Adult Fat Body    1994.1 Adult Salivary Gland    1044.1 Adult Heart    1357.525 Adult VirginFemale Spermatheca    2113.8 Adult InseminatedFemale Spermatheca    2336.4 Adult Ovary    1595.4 Adult Testis    559.3 Adult Male Accessory Gland    1974.1 Adult Carcass    1275.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1145.025) Larval Midgut  513.5 Larval Hindgut  (823.4) Larval Malpighian Tubules  (871) Larval Fat Body  (1417.5) Larval Salivary Gland  (2572.9) Larval Trachea  (1649.95) Larval Carcass  (1133.875) Adult Head  (1085) Adult Eye  (862.075) Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop  (791.3) Adult Midgut  (699.7) Adult Hindgut  (632.9) Adult Malpighian Tubules  (1043.4) Adult Fat Body  (1994.1) Adult Salivary Gland  (1044.1) Adult Heart  (1357.525) Adult VirginFemale Spermatheca  (2113.8) Adult InseminatedFemale Spermatheca  (2336.4) Adult Ovary  (1595.4) Adult Testis  (559.3) Adult Male Accessory Gland  (1974.1) Adult Carcass  (1275.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1145.025) Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body  (1417.5) Larval Salivary Gland  (2572.9) Larval Trachea  (1649.95) Larval Carcass  (1133.875) Adult Head  (1085) Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules  1043.4 Adult Fat Body  (1994.1) Adult Salivary Gland  1044.1 Adult Heart  (1357.525) Adult VirginFemale Spermatheca  (2113.8) Adult InseminatedFemale Spermatheca  (2336.4) Adult Ovary  (1595.4) Adult Testis    559.3 Adult Male Accessory Gland  (1974.1) Adult Carcass  (1275.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1145.025 Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body    1417.5 Larval Salivary Gland    2572.9 Larval Trachea    1649.95 Larval Carcass    1133.875 Adult Head    1085 Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules    1043.4 Adult Fat Body    1994.1 Adult Salivary Gland    1044.1 Adult Heart    1357.525 Adult VirginFemale Spermatheca    2113.8 Adult InseminatedFemale Spermatheca    2336.4 Adult Ovary    1595.4 Adult Testis    559.3 Adult Male Accessory Gland    1974.1 Adult Carcass    1275.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1145.025 Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body    1417.5 Larval Salivary Gland    2572.9 Larval Trachea    1649.95 Larval Carcass    1133.875 Adult Head    1085 Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules    1043.4 Adult Fat Body    1994.1 Adult Salivary Gland    1044.1 Adult Heart    1357.525 Adult VirginFemale Spermatheca    2113.8 Adult InseminatedFemale Spermatheca    2336.4 Adult Ovary    1595.4 Adult Testis    559.3 Adult Male Accessory Gland    1974.1 Adult Carcass    1275.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1145.025) Larval Midgut  513.5 Larval Hindgut  (823.4) Larval Malpighian Tubules  (871) Larval Fat Body  (1417.5) Larval Salivary Gland  (2572.9) Larval Trachea  (1649.95) Larval Carcass  (1133.875) Adult Head  (1085) Adult Eye  (862.075) Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop  791.3 Adult Midgut  699.7 Adult Hindgut  632.9 Adult Malpighian Tubules  (1043.4) Adult Fat Body  (1994.1) Adult Salivary Gland  (1044.1) Adult Heart  (1357.525) Adult VirginFemale Spermatheca  (2113.8) Adult InseminatedFemale Spermatheca  (2336.4) Adult Ovary  (1595.4) Adult Testis  559.3 Adult Male Accessory Gland  (1974.1) Adult Carcass  (1275.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1145.025 Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body  1417.5 Larval Salivary Gland  (2572.9) Larval Trachea  1649.95 Larval Carcass  1133.875 Adult Head  1085 Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules  1043.4 Adult Fat Body  (1994.1) Adult Salivary Gland  1044.1 Adult Heart  1357.525 Adult VirginFemale Spermatheca  (2113.8) Adult InseminatedFemale Spermatheca  (2336.4) Adult Ovary  1595.4 Adult Testis    559.3 Adult Male Accessory Gland  (1974.1) Adult Carcass  1275.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1145.025 Larval Midgut    513.5 Larval Hindgut    823.4 Larval Malpighian Tubules    871 Larval Fat Body    1417.5 Larval Salivary Gland    2572.9 Larval Trachea    1649.95 Larval Carcass    1133.875 Adult Head    1085 Adult Eye    862.075 Adult Brain    398.8 Adult Thoracic-Abdominal Ganglion    478.9 Adult Crop    791.3 Adult Midgut    699.7 Adult Hindgut    632.9 Adult Malpighian Tubules    1043.4 Adult Fat Body    1994.1 Adult Salivary Gland    1044.1 Adult Heart    1357.525 Adult VirginFemale Spermatheca    2113.8 Adult InseminatedFemale Spermatheca    2336.4 Adult Ovary    1595.4 Adult Testis    559.3 Adult Male Accessory Gland    1974.1 Adult Carcass    1275.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1085   NA  Eye    862.075   NA  Brain    398.8   1145.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    478.9   NA  Crop    791.3   513.5  Midgut    699.7   823.4  Hindgut    632.9   871  Malpighian Tubules    1043.4   1417.5  Fat Body    1994.1   2572.9  Salivary Gland    1044.1   NA  Heart    1357.525   1649.95  Trachea    NA   NA  VirginFemale Spermatheca    2113.8   NA  InseminatedFemale Spermatheca    2336.4   NA  Ovary    1595.4   NA  Testis    559.3   NA  Male Accessory Gland    1974.1   1133.875  Carcass    1275.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    207 central nervous system, larvae L3    192 central nervous system, pupae P8    58 head, virgin 1-day female    204 head, virgin 4-day female    144 head, virgin 20-day female    118 head, mated 1-day female    130 head, mated 4-day female    195 head, mated 20-day female    111 head, mated 1-day male    79 head, mated 4-day male    111 head, mated 20-day male    107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    83 digestive system, 4-day adult    112 digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae    106 fat body, pupae P8    128 carcass, larvae L3 wandering    213 carcass, 1-day adult    142 carcass, 4-day adult    233 carcass, 20-day adult    128 ovary, virgin 4-day female    378 ovary, mated 4-day female    359 testis, mated 4-day male    91 accessory gland, mated 4-day male    104 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (207) central nervous system, larvae L3  (192) central nervous system, pupae P8  (58) head, virgin 1-day female  (204) head, virgin 4-day female  (144) head, virgin 20-day female  (118) head, mated 1-day female  (130) head, mated 4-day female  (195) head, mated 20-day female  (111) head, mated 1-day male  (79) head, mated 4-day male  (111) head, mated 20-day male  (107) salivary gland, larvae L3 wandering  (75) salivary gland, white prepupae  (50) digestive system, larvae L3 wandering  (109) digestive system, 1-day adult  (83) digestive system, 4-day adult  (112) digestive system, 20-day adult  (54) fat body, larvae L3 wandering  (87) fat body, white prepupae  (106) fat body, pupae P8  (128) carcass, larvae L3 wandering  (213) carcass, 1-day adult  (142) carcass, 4-day adult  (233) carcass, 20-day adult  (128) ovary, virgin 4-day female  (378) ovary, mated 4-day female  (359) testis, mated 4-day male  (91) accessory gland, mated 4-day male  (104) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (207) central nervous system, larvae L3  (192) central nervous system, pupae P8    58 head, virgin 1-day female  (204) head, virgin 4-day female  (144) head, virgin 20-day female  (118) head, mated 1-day female  (130) head, mated 4-day female  (195) head, mated 20-day female  (111) head, mated 1-day male    79 head, mated 4-day male  (111) head, mated 20-day male  107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering  (109) digestive system, 1-day adult    83 digestive system, 4-day adult  (112) digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae  106 fat body, pupae P8  (128) carcass, larvae L3 wandering  (213) carcass, 1-day adult  (142) carcass, 4-day adult  (233) carcass, 20-day adult  (128) ovary, virgin 4-day female  (378) ovary, mated 4-day female  (359) testis, mated 4-day male    91 accessory gland, mated 4-day male  104 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    207 central nervous system, larvae L3    192 central nervous system, pupae P8    58 head, virgin 1-day female    204 head, virgin 4-day female    144 head, virgin 20-day female    118 head, mated 1-day female    130 head, mated 4-day female    195 head, mated 20-day female    111 head, mated 1-day male    79 head, mated 4-day male    111 head, mated 20-day male    107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    83 digestive system, 4-day adult    112 digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae    106 fat body, pupae P8    128 carcass, larvae L3 wandering    213 carcass, 1-day adult    142 carcass, 4-day adult    233 carcass, 20-day adult    128 ovary, virgin 4-day female    378 ovary, mated 4-day female    359 testis, mated 4-day male    91 accessory gland, mated 4-day male    104 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    207 central nervous system, larvae L3    192 central nervous system, pupae P8    58 head, virgin 1-day female    204 head, virgin 4-day female    144 head, virgin 20-day female    118 head, mated 1-day female    130 head, mated 4-day female    195 head, mated 20-day female    111 head, mated 1-day male    79 head, mated 4-day male    111 head, mated 20-day male    107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    83 digestive system, 4-day adult    112 digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae    106 fat body, pupae P8    128 carcass, larvae L3 wandering    213 carcass, 1-day adult    142 carcass, 4-day adult    233 carcass, 20-day adult    128 ovary, virgin 4-day female    378 ovary, mated 4-day female    359 testis, mated 4-day male    91 accessory gland, mated 4-day male    104 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (207) central nervous system, larvae L3  (192) central nervous system, pupae P8  (58) head, virgin 1-day female  (204) head, virgin 4-day female  (144) head, virgin 20-day female  (118) head, mated 1-day female  (130) head, mated 4-day female  (195) head, mated 20-day female  (111) head, mated 1-day male  (79) head, mated 4-day male  (111) head, mated 20-day male  (107) salivary gland, larvae L3 wandering  (75) salivary gland, white prepupae  (50) digestive system, larvae L3 wandering  (109) digestive system, 1-day adult  (83) digestive system, 4-day adult  (112) digestive system, 20-day adult  (54) fat body, larvae L3 wandering  (87) fat body, white prepupae  (106) fat body, pupae P8  (128) carcass, larvae L3 wandering  (213) carcass, 1-day adult  (142) carcass, 4-day adult  (233) carcass, 20-day adult  (128) ovary, virgin 4-day female  (378) ovary, mated 4-day female  (359) testis, mated 4-day male  (91) accessory gland, mated 4-day male  (104) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (207) central nervous system, larvae L3  (192) central nervous system, pupae P8    58 head, virgin 1-day female  (204) head, virgin 4-day female  (144) head, virgin 20-day female  118 head, mated 1-day female  130 head, mated 4-day female  (195) head, mated 20-day female  111 head, mated 1-day male    79 head, mated 4-day male  111 head, mated 20-day male  107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering  109 digestive system, 1-day adult    83 digestive system, 4-day adult  112 digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae  106 fat body, pupae P8  128 carcass, larvae L3 wandering  (213) carcass, 1-day adult  142 carcass, 4-day adult  (233) carcass, 20-day adult  128 ovary, virgin 4-day female  (378) ovary, mated 4-day female  (359) testis, mated 4-day male    91 accessory gland, mated 4-day male  104 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    207 central nervous system, larvae L3    192 central nervous system, pupae P8    58 head, virgin 1-day female    204 head, virgin 4-day female    144 head, virgin 20-day female    118 head, mated 1-day female    130 head, mated 4-day female    195 head, mated 20-day female    111 head, mated 1-day male    79 head, mated 4-day male    111 head, mated 20-day male    107 salivary gland, larvae L3 wandering    75 salivary gland, white prepupae    50 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    83 digestive system, 4-day adult    112 digestive system, 20-day adult    54 fat body, larvae L3 wandering    87 fat body, white prepupae    106 fat body, pupae P8    128 carcass, larvae L3 wandering    213 carcass, 1-day adult    142 carcass, 4-day adult    233 carcass, 20-day adult    128 ovary, virgin 4-day female    378 ovary, mated 4-day female    359 testis, mated 4-day male    91 accessory gland, mated 4-day male    104 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    236 embryo 02-04hr    380 embryo 04-06hr    237 embryo 06-08hr    188 embryo 08-10hr    210 embryo 10-12hr    171 embryo 12-14hr    211 embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr    109 larva L1    190 larva L2    275 larva L3 12hr old    188 larva L3 puffstage 1-2    129 larva L3 puffstage 3-6    106 larva L3 puffstage 7-9    136 white prepupae new    144 white prepupae 12hr    94 white prepupae 24hr    113 pupae 2d postWPP    117 pupae 3d postWPP    103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day    125 adult female 05day    290 adult female 30day    276 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (236) embryo 02-04hr  (380) embryo 04-06hr  (237) embryo 06-08hr  (188) embryo 08-10hr  (210) embryo 10-12hr  (171) embryo 12-14hr  (211) embryo 14-16hr  (95) embryo 16-18hr  (95) embryo 18-20hr  (69) embryo 20-22hr  (97) embryo 22-24hr  (109) larva L1  (190) larva L2  (275) larva L3 12hr old  (188) larva L3 puffstage 1-2  (129) larva L3 puffstage 3-6  (106) larva L3 puffstage 7-9  (136) white prepupae new  (144) white prepupae 12hr  (94) white prepupae 24hr  (113) pupae 2d postWPP  (117) pupae 3d postWPP  (103) pupae 4d postWPP  (70) adult male 01day  (95) adult male 05day  (82) adult male 30day  (52) adult female 01day  (125) adult female 05day  (290) adult female 30day  (276) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (236) embryo 02-04hr  (380) embryo 04-06hr  (237) embryo 06-08hr  (188) embryo 08-10hr  (210) embryo 10-12hr  (171) embryo 12-14hr  (211) embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr  (109) larva L1  (190) larva L2  (275) larva L3 12hr old  (188) larva L3 puffstage 1-2  (129) larva L3 puffstage 3-6  106 larva L3 puffstage 7-9  (136) white prepupae new  (144) white prepupae 12hr    94 white prepupae 24hr  (113) pupae 2d postWPP  (117) pupae 3d postWPP  103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day  (125) adult female 05day  (290) adult female 30day  (276) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    236 embryo 02-04hr    380 embryo 04-06hr    237 embryo 06-08hr    188 embryo 08-10hr    210 embryo 10-12hr    171 embryo 12-14hr    211 embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr    109 larva L1    190 larva L2    275 larva L3 12hr old    188 larva L3 puffstage 1-2    129 larva L3 puffstage 3-6    106 larva L3 puffstage 7-9    136 white prepupae new    144 white prepupae 12hr    94 white prepupae 24hr    113 pupae 2d postWPP    117 pupae 3d postWPP    103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day    125 adult female 05day    290 adult female 30day    276 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    236 embryo 02-04hr    380 embryo 04-06hr    237 embryo 06-08hr    188 embryo 08-10hr    210 embryo 10-12hr    171 embryo 12-14hr    211 embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr    109 larva L1    190 larva L2    275 larva L3 12hr old    188 larva L3 puffstage 1-2    129 larva L3 puffstage 3-6    106 larva L3 puffstage 7-9    136 white prepupae new    144 white prepupae 12hr    94 white prepupae 24hr    113 pupae 2d postWPP    117 pupae 3d postWPP    103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day    125 adult female 05day    290 adult female 30day    276 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (236) embryo 02-04hr  (380) embryo 04-06hr  (237) embryo 06-08hr  (188) embryo 08-10hr  (210) embryo 10-12hr  (171) embryo 12-14hr  (211) embryo 14-16hr  (95) embryo 16-18hr  (95) embryo 18-20hr  (69) embryo 20-22hr  (97) embryo 22-24hr  (109) larva L1  (190) larva L2  (275) larva L3 12hr old  (188) larva L3 puffstage 1-2  (129) larva L3 puffstage 3-6  (106) larva L3 puffstage 7-9  (136) white prepupae new  (144) white prepupae 12hr  (94) white prepupae 24hr  (113) pupae 2d postWPP  (117) pupae 3d postWPP  (103) pupae 4d postWPP  (70) adult male 01day  (95) adult male 05day  (82) adult male 30day  (52) adult female 01day  (125) adult female 05day  (290) adult female 30day  (276) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (236) embryo 02-04hr  (380) embryo 04-06hr  (237) embryo 06-08hr  (188) embryo 08-10hr  (210) embryo 10-12hr  (171) embryo 12-14hr  (211) embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr  109 larva L1  (190) larva L2  (275) larva L3 12hr old  (188) larva L3 puffstage 1-2  129 larva L3 puffstage 3-6  106 larva L3 puffstage 7-9  136 white prepupae new  (144) white prepupae 12hr    94 white prepupae 24hr  113 pupae 2d postWPP  117 pupae 3d postWPP  103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day  125 adult female 05day  (290) adult female 30day  (276) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    236 embryo 02-04hr    380 embryo 04-06hr    237 embryo 06-08hr    188 embryo 08-10hr    210 embryo 10-12hr    171 embryo 12-14hr    211 embryo 14-16hr    95 embryo 16-18hr    95 embryo 18-20hr    69 embryo 20-22hr    97 embryo 22-24hr    109 larva L1    190 larva L2    275 larva L3 12hr old    188 larva L3 puffstage 1-2    129 larva L3 puffstage 3-6    106 larva L3 puffstage 7-9    136 white prepupae new    144 white prepupae 12hr    94 white prepupae 24hr    113 pupae 2d postWPP    117 pupae 3d postWPP    103 pupae 4d postWPP    70 adult male 01day    95 adult male 05day    82 adult male 30day    52 adult female 01day    125 adult female 05day    290 adult female 30day    276 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    509 Schneider line 2 Sg4    182 embryonic 1182-4H    187 embryonic GM2    155 embryonic Kc167    135 embryonic S1    238 embryonic S3    382 leg disc CME L1    304 wing disc CME-W2    289 wing disc ML-DmD8    272 wing disc ML-DmD9    208 wing disc ML-DmD16-c3    278 wing disc ML-DmD21    249 wing disc ML-DmD32    196 haltere disc ML-DmD17-c3    267 eye-antennal disc ML-DmD11    265 antennal disc ML-DmD20-c5    210 mixed discs ML-DmD4-c1    236 CNS ML-DmBG1-c1    402 CNS ML-DmBG2-c2    271 tumorous blood cells mbn2    206 ovary fGS/OSS    131 ovary OSC    246 ovary OSS    136 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (509) Schneider line 2 Sg4  (182) embryonic 1182-4H  (187) embryonic GM2  (155) embryonic Kc167  (135) embryonic S1  (238) embryonic S3  (382) leg disc CME L1  (304) wing disc CME-W2  (289) wing disc ML-DmD8  (272) wing disc ML-DmD9  (208) wing disc ML-DmD16-c3  (278) wing disc ML-DmD21  (249) wing disc ML-DmD32  (196) haltere disc ML-DmD17-c3  (267) eye-antennal disc ML-DmD11  (265) antennal disc ML-DmD20-c5  (210) mixed discs ML-DmD4-c1  (236) CNS ML-DmBG1-c1  (402) CNS ML-DmBG2-c2  (271) tumorous blood cells mbn2  (206) ovary fGS/OSS  (131) ovary OSC  (246) ovary OSS  (136) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (509) Schneider line 2 Sg4  (182) embryonic 1182-4H  (187) embryonic GM2  (155) embryonic Kc167  (135) embryonic S1  (238) embryonic S3  (382) leg disc CME L1  (304) wing disc CME-W2  (289) wing disc ML-DmD8  (272) wing disc ML-DmD9  (208) wing disc ML-DmD16-c3  (278) wing disc ML-DmD21  (249) wing disc ML-DmD32  (196) haltere disc ML-DmD17-c3  (267) eye-antennal disc ML-DmD11  (265) antennal disc ML-DmD20-c5  (210) mixed discs ML-DmD4-c1  (236) CNS ML-DmBG1-c1  (402) CNS ML-DmBG2-c2  (271) tumorous blood cells mbn2  (206) ovary fGS/OSS  (131) ovary OSC  (246) ovary OSS  (136) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    509 Schneider line 2 Sg4    182 embryonic 1182-4H    187 embryonic GM2    155 embryonic Kc167    135 embryonic S1    238 embryonic S3    382 leg disc CME L1    304 wing disc CME-W2    289 wing disc ML-DmD8    272 wing disc ML-DmD9    208 wing disc ML-DmD16-c3    278 wing disc ML-DmD21    249 wing disc ML-DmD32    196 haltere disc ML-DmD17-c3    267 eye-antennal disc ML-DmD11    265 antennal disc ML-DmD20-c5    210 mixed discs ML-DmD4-c1    236 CNS ML-DmBG1-c1    402 CNS ML-DmBG2-c2    271 tumorous blood cells mbn2    206 ovary fGS/OSS    131 ovary OSC    246 ovary OSS    136 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    509 Schneider line 2 Sg4    182 embryonic 1182-4H    187 embryonic GM2    155 embryonic Kc167    135 embryonic S1    238 embryonic S3    382 leg disc CME L1    304 wing disc CME-W2    289 wing disc ML-DmD8    272 wing disc ML-DmD9    208 wing disc ML-DmD16-c3    278 wing disc ML-DmD21    249 wing disc ML-DmD32    196 haltere disc ML-DmD17-c3    267 eye-antennal disc ML-DmD11    265 antennal disc ML-DmD20-c5    210 mixed discs ML-DmD4-c1    236 CNS ML-DmBG1-c1    402 CNS ML-DmBG2-c2    271 tumorous blood cells mbn2    206 ovary fGS/OSS    131 ovary OSC    246 ovary OSS    136 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (509) Schneider line 2 Sg4  (182) embryonic 1182-4H  (187) embryonic GM2  (155) embryonic Kc167  (135) embryonic S1  (238) embryonic S3  (382) leg disc CME L1  (304) wing disc CME-W2  (289) wing disc ML-DmD8  (272) wing disc ML-DmD9  (208) wing disc ML-DmD16-c3  (278) wing disc ML-DmD21  (249) wing disc ML-DmD32  (196) haltere disc ML-DmD17-c3  (267) eye-antennal disc ML-DmD11  (265) antennal disc ML-DmD20-c5  (210) mixed discs ML-DmD4-c1  (236) CNS ML-DmBG1-c1  (402) CNS ML-DmBG2-c2  (271) tumorous blood cells mbn2  (206) ovary fGS/OSS  (131) ovary OSC  (246) ovary OSS  (136) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (509) Schneider line 2 Sg4  (182) embryonic 1182-4H  (187) embryonic GM2  (155) embryonic Kc167  135 embryonic S1  (238) embryonic S3  (382) leg disc CME L1  (304) wing disc CME-W2  (289) wing disc ML-DmD8  (272) wing disc ML-DmD9  (208) wing disc ML-DmD16-c3  (278) wing disc ML-DmD21  (249) wing disc ML-DmD32  (196) haltere disc ML-DmD17-c3  (267) eye-antennal disc ML-DmD11  (265) antennal disc ML-DmD20-c5  (210) mixed discs ML-DmD4-c1  (236) CNS ML-DmBG1-c1  (402) CNS ML-DmBG2-c2  (271) tumorous blood cells mbn2  (206) ovary fGS/OSS  131 ovary OSC  (246) ovary OSS  136 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    509 Schneider line 2 Sg4    182 embryonic 1182-4H    187 embryonic GM2    155 embryonic Kc167    135 embryonic S1    238 embryonic S3    382 leg disc CME L1    304 wing disc CME-W2    289 wing disc ML-DmD8    272 wing disc ML-DmD9    208 wing disc ML-DmD16-c3    278 wing disc ML-DmD21    249 wing disc ML-DmD32    196 haltere disc ML-DmD17-c3    267 eye-antennal disc ML-DmD11    265 antennal disc ML-DmD20-c5    210 mixed discs ML-DmD4-c1    236 CNS ML-DmBG1-c1    402 CNS ML-DmBG2-c2    271 tumorous blood cells mbn2    206 ovary fGS/OSS    131 ovary OSC    246 ovary OSS    136 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult    203 Cadmium 50 mM 6 hrs, larvae L3    171 Cadmium 50 mM 12 hrs, larvae L3    216 Cadmium 50 mM 48 hrs, 4-day adult    211 Cadmium 100 mM 48 hrs, 4-day adult    210 Copper 0.5 mM 12 hrs, larvae L3    162 Copper 15 mM 48 hrs, 4-day adult    114 Zinc 5 mM 12 hrs, larvae L3    132 Zinc 4.5 mM 48 hrs, 4-day adult    125 Ethanol 2.5% 3 hrs, larvae L3    189 Ethanol 5% 3 hrs, larvae L3    196 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    215 Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult    193 Paraquat 10 mM 48 hrs, 4-day adult    163 Rotenone 2 μg 12 hrs, larvae L3    252 Rotenone 8 μg 12 hrs, larvae L3    182 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (99) cold shock, 4-day adult  (77) heat shock, 4-day adult  (203) Cadmium 50 mM 6 hrs, larvae L3  (171) Cadmium 50 mM 12 hrs, larvae L3  (216) Cadmium 50 mM 48 hrs, 4-day adult  (211) Cadmium 100 mM 48 hrs, 4-day adult  (210) Copper 0.5 mM 12 hrs, larvae L3  (162) Copper 15 mM 48 hrs, 4-day adult  (114) Zinc 5 mM 12 hrs, larvae L3  (132) Zinc 4.5 mM 48 hrs, 4-day adult  (125) Ethanol 2.5% 3 hrs, larvae L3  (189) Ethanol 5% 3 hrs, larvae L3  (196) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (215) Caffeine 25 mg/ml 48 hrs, 4-day adult  (71) Paraquat 5 mM 48 hrs, 4-day adult  (193) Paraquat 10 mM 48 hrs, 4-day adult  (163) Rotenone 2 μg 12 hrs, larvae L3  (252) Rotenone 8 μg 12 hrs, larvae L3  (182) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult  (203) Cadmium 50 mM 6 hrs, larvae L3  (171) Cadmium 50 mM 12 hrs, larvae L3  (216) Cadmium 50 mM 48 hrs, 4-day adult  (211) Cadmium 100 mM 48 hrs, 4-day adult  (210) Copper 0.5 mM 12 hrs, larvae L3  (162) Copper 15 mM 48 hrs, 4-day adult  (114) Zinc 5 mM 12 hrs, larvae L3  (132) Zinc 4.5 mM 48 hrs, 4-day adult  (125) Ethanol 2.5% 3 hrs, larvae L3  (189) Ethanol 5% 3 hrs, larvae L3  (196) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (215) Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult  (193) Paraquat 10 mM 48 hrs, 4-day adult  (163) Rotenone 2 μg 12 hrs, larvae L3  (252) Rotenone 8 μg 12 hrs, larvae L3  (182) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult    203 Cadmium 50 mM 6 hrs, larvae L3    171 Cadmium 50 mM 12 hrs, larvae L3    216 Cadmium 50 mM 48 hrs, 4-day adult    211 Cadmium 100 mM 48 hrs, 4-day adult    210 Copper 0.5 mM 12 hrs, larvae L3    162 Copper 15 mM 48 hrs, 4-day adult    114 Zinc 5 mM 12 hrs, larvae L3    132 Zinc 4.5 mM 48 hrs, 4-day adult    125 Ethanol 2.5% 3 hrs, larvae L3    189 Ethanol 5% 3 hrs, larvae L3    196 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    215 Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult    193 Paraquat 10 mM 48 hrs, 4-day adult    163 Rotenone 2 μg 12 hrs, larvae L3    252 Rotenone 8 μg 12 hrs, larvae L3    182 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult    203 Cadmium 50 mM 6 hrs, larvae L3    171 Cadmium 50 mM 12 hrs, larvae L3    216 Cadmium 50 mM 48 hrs, 4-day adult    211 Cadmium 100 mM 48 hrs, 4-day adult    210 Copper 0.5 mM 12 hrs, larvae L3    162 Copper 15 mM 48 hrs, 4-day adult    114 Zinc 5 mM 12 hrs, larvae L3    132 Zinc 4.5 mM 48 hrs, 4-day adult    125 Ethanol 2.5% 3 hrs, larvae L3    189 Ethanol 5% 3 hrs, larvae L3    196 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    215 Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult    193 Paraquat 10 mM 48 hrs, 4-day adult    163 Rotenone 2 μg 12 hrs, larvae L3    252 Rotenone 8 μg 12 hrs, larvae L3    182 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (99) cold shock, 4-day adult  (77) heat shock, 4-day adult  (203) Cadmium 50 mM 6 hrs, larvae L3  (171) Cadmium 50 mM 12 hrs, larvae L3  (216) Cadmium 50 mM 48 hrs, 4-day adult  (211) Cadmium 100 mM 48 hrs, 4-day adult  (210) Copper 0.5 mM 12 hrs, larvae L3  (162) Copper 15 mM 48 hrs, 4-day adult  (114) Zinc 5 mM 12 hrs, larvae L3  (132) Zinc 4.5 mM 48 hrs, 4-day adult  (125) Ethanol 2.5% 3 hrs, larvae L3  (189) Ethanol 5% 3 hrs, larvae L3  (196) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (215) Caffeine 25 mg/ml 48 hrs, 4-day adult  (71) Paraquat 5 mM 48 hrs, 4-day adult  (193) Paraquat 10 mM 48 hrs, 4-day adult  (163) Rotenone 2 μg 12 hrs, larvae L3  (252) Rotenone 8 μg 12 hrs, larvae L3  (182) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult  (203) Cadmium 50 mM 6 hrs, larvae L3  (171) Cadmium 50 mM 12 hrs, larvae L3  (216) Cadmium 50 mM 48 hrs, 4-day adult  (211) Cadmium 100 mM 48 hrs, 4-day adult  (210) Copper 0.5 mM 12 hrs, larvae L3  (162) Copper 15 mM 48 hrs, 4-day adult  114 Zinc 5 mM 12 hrs, larvae L3  132 Zinc 4.5 mM 48 hrs, 4-day adult  125 Ethanol 2.5% 3 hrs, larvae L3  (189) Ethanol 5% 3 hrs, larvae L3  (196) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (215) Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult  (193) Paraquat 10 mM 48 hrs, 4-day adult  (163) Rotenone 2 μg 12 hrs, larvae L3  (252) Rotenone 8 μg 12 hrs, larvae L3  (182) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    99 cold shock, 4-day adult    77 heat shock, 4-day adult    203 Cadmium 50 mM 6 hrs, larvae L3    171 Cadmium 50 mM 12 hrs, larvae L3    216 Cadmium 50 mM 48 hrs, 4-day adult    211 Cadmium 100 mM 48 hrs, 4-day adult    210 Copper 0.5 mM 12 hrs, larvae L3    162 Copper 15 mM 48 hrs, 4-day adult    114 Zinc 5 mM 12 hrs, larvae L3    132 Zinc 4.5 mM 48 hrs, 4-day adult    125 Ethanol 2.5% 3 hrs, larvae L3    189 Ethanol 5% 3 hrs, larvae L3    196 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    215 Caffeine 25 mg/ml 48 hrs, 4-day adult    71 Paraquat 5 mM 48 hrs, 4-day adult    193 Paraquat 10 mM 48 hrs, 4-day adult    163 Rotenone 2 μg 12 hrs, larvae L3    252 Rotenone 8 μg 12 hrs, larvae L3    182 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD01705 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032198 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4912-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for eEF1δ Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 eEF1δGD11469 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of eEF1δ Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of eEF1δ Class Mutagen Stocks Known lesion eEF1δGD11469 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eEF1δJF03284 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eEF1δKK101520 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eEF1δNIG.4912R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6026 (Ryder, 2004.4.26) Df(2L)Exel8024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}CG5694KG08725 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
guanyl-nucleotide exchange factor activity non-traceable author statement (Swiss-Prot Project Members, 2000.10.1, Mi et al., 2001.12.13) translation elongation factor activity inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Lasko, 2000) non-traceable author statement (Swiss-Prot Project Members, 2000.10.1)
Biological Process
CV term Evidence References
translational elongation inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Lasko, 2000) non-traceable author statement (Swiss-Prot Project Members, 2000.10.1)
Cellular Component
CV term Evidence References
eukaryotic translation elongation factor 1 complex inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Lasko, 2000) non-traceable author statement (Swiss-Prot Project Members, 2000.10.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
eEF1δ - ATPsyn-Cf6 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Adam anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - AnxB10 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG10638 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG1105 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG11200 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG11790 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG1246 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG1265 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG13532 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG14020 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG14556 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG14968 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG15643 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG16817 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG17260 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG18335 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG2982 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG31712 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG40160 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG43755 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG5174 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG5646 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG6084 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG6321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG6543 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - CG6852 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG7091 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG7288 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CG9920 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - CSN4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Chd64 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Crc experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Cyp9b2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Cyt-c-d anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Der-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Df31 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Eb1 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Ef1α100E anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) eEF1δ - Ef1γ experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Eno experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Fim experimental knowledge based (Guruharsha et al., 2011) eEF1δ - GalNAc-T1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - GstE6 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - GstO3 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Hop experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Inos experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Lac anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - M6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - MFS3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Mdh2 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Moe experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Nacα experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Ndfip anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Nlp experimental knowledge based (Guruharsha et al., 2011) eEF1δ - PHGPx anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) eEF1δ - Pdi experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Prosα1 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - RASSF8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - SP2637 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - Sh3β experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Sply anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - TER94 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - Uch experimental knowledge based (Guruharsha et al., 2011) eEF1δ - ZnT63C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - awd experimental knowledge based (Guruharsha et al., 2011) eEF1δ - capt experimental knowledge based (Guruharsha et al., 2011) eEF1δ - dUTPase experimental knowledge based (Guruharsha et al., 2011) eEF1δ - fax experimental knowledge based (Guruharsha et al., 2011) eEF1δ - mRpL19 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - msl-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eEF1δ - mus209 experimental knowledge based (Guruharsha et al., 2011) eEF1δ - regucalcin experimental knowledge based (Guruharsha et al., 2011) eEF1δ - scf experimental knowledge based (Guruharsha et al., 2011) eEF1δ - yellow-d anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions eEF1δ allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60454 DroID - A comprehensive database of gene and protein interactions. • FBgn0032198 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34363
Orthologs
OrthoDB Orthologs (45) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6HX5MD Dipteran inclusive ortholog search EOG64MZ25 Insect inclusive ortholog search EOG6K998C Arthropod inclusive ortholog search EOG6PVMFR Metazoa inclusive ortholog search EOG6B09J6
Orthologs in Drosophila Species (EOG6HX5MD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\eEF1δ     Drosophila simulans   Dsim\GD23666 Y   Drosophila sechellia   Dsec\GM18026 Y   Drosophila erecta   Dere\GG10094 Y   Drosophila yakuba   Dyak\eEF1δ Y   Drosophila ananassae   Dana\GF15753 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18520 Y   Drosophila persimilis   Dper\GL18972 Y   Drosophila grimshawi   Dgri\GH13553 Y
Orthologs in non-Drosophila Dipterans (EOG64MZ25)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009313   Anopheles gambiae Malaria mosquito  Agam\AGAP004235   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004079
Orthologs in non-Dipteran Insects (EOG6K998C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB42862   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG019636   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19814   Atta cephalotes Leafcutter ant  Acep\ACEP17432   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23076   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18254   Linepithema humile Argentine ant  Lhum\LH19383   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14491   Solenopsis invicta Red fire ant  Sinv\SINV10915   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006186   Bombyx mori Silkmoth  Bmor\ef-1d   Pediculus humanus Human body louse  Phum\PHUM455370
Orthologs in non-Insect Arthropods (EOG6PVMFR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW013304
Orthologs in non-Arthropod Metazoa (EOG6B09J6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F54H12.6 Y Caenorhabditis elegans Nematode  Cele\Y41E3.10 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000960gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000959gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015867gn Y Danio rerio Zebrafish  Drer\eef1db Y Danio rerio Zebrafish  Drer\eef1da Y Danio rerio Zebrafish  Drer\eef1b2 Y Xenopus tropicalis Western clawed frog  Xtro\eef1d Y Xenopus tropicalis Western clawed frog  Xtro\eef1b2 Y Gallus gallus Domestic chicken  Ggal\EEF1D Y Gallus gallus Domestic chicken  Ggal\EEF1B2 Y Mus musculus House mouse  Mmus\Eef1b Y Mus musculus House mouse  Mmus\Eef1d Y Rattus norvegicus Norway rat  Rnor\Eef1b2l Y Rattus norvegicus Norway rat  Rnor\Eef1b2 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030934 Y Rattus norvegicus Norway rat  Rnor\Eef1d Y Homo sapiens Human  Hsap\EEF1D Y Homo sapiens Human  Hsap\EEF1B2 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\EEF1D     Hsap\EEF1B2
AAA Orthologs (8) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23666 Drosophila sechellia Dsec\GM18026 Drosophila erecta Dere\GG10094 Drosophila yakuba Dyak\eEF1δ Drosophila ananassae Dana\GF15753 Drosophila pseudoobscura pseudoobscura Dpse\GA18520 Drosophila persimilis Dper\GL18972 Drosophila grimshawi Dgri\GH13553
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	29605 y1 v1; P{TRiP.JF03284}attP2
VDRC	v107007 P{KK101520}VIE-260B v26658 w1118 P{GD11469}v26658
Genomic Clones ( 1 )
	BACR07H08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 114 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD01705
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT06833 GH07659 GM03792 GM03948 GM19278 GM22959 GM26950 GM31518 LD13116 LD20310 LD20311 LD24615 LD32849 LD37790 LP01516 RE17705 RE18556 RE18862 RE20001 RE24624 RE28139 RE35676 RE40012 RE42085 RE69365 RH04573 RH05855 RH08812 RH08832 RH09692 RH14031 RH14390 RH16740 RH17404 RH21241 RH37679 RH38186 RH40140 RH56805 RH62303 RH63096 RH63311 SD04268 SD05259 SD07622 SD11026 SD11350 SD11357 SD17848 SD25388
Other clones	76653 281183 286410 292468 294157 Dmel_dig_006258_0657_3601 Dmel_dig_010570_0642_2860 Dmel_dig_011090_0659_2264 Dmel_neb_006107_0393_2397 Dmel_neb_007885_0645_0268 Dmel_neb_010698_0878_2411 EC30525 EK176824 EN03908 EN07064 EN07518 EN11911 FGH109F03 FGH118D01 FGM222G05 FGM234G05 FGM324H06 RE01729 RP004030384 RP004032436 RP004076607 RP004100303 RP004120288 RP004124611 RP004126038 RP004129651 RP004132605 RP004168938 RP004170564 RP004196946 RP004206821 RP004214111 RP004220565 RP004221293 RP004227449 RP004230787 RP004231348 RP004246388 RP004249872 RP004253949 RP004254390 RP004269811 RP004312159 RP004374022 RP004392896 RP004398099 RP004405906 RP004436618 RP004481736 RP004485275 RP004492744 RP004499267 RP004518133 RP004526568 RP004527261 RP004535084 RP004541430 RP004542155
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032198 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34363
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: eEF1δ CG4912 (Lasko, 2000)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135517 NM_164895 RefSeq (Proteins) • NP_609361 NP_723536 DDBJ / EMBL / GenBank • AA816438 AAF52879 AAF52880 AAO25038 AW941480 BT003281 Entrez Gene - A searchable database of RefSeq genes. • 34363 UniProtKB/Swiss-Prot • Q9VL18
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Translation elongation factor EF1B, beta/delta chains, conserved site (IPR001326) Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange (IPR014038) Translation elongation factor EF1B/ribosomal protein S6 (IPR014717) Elongation factor 1 beta central acidic region, eukaryote (IPR018940) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD01705
Linkouts
	BioGRID - A database of protein and genetic interactions • 60454 DroID - A comprehensive database of gene and protein interactions. • FBgn0032198 DRSC - Results from RNAi screens. • FBgn0032198 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032198 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4912-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032198 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34363 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34363 modMine - Data generated by the modENCODE project. • FBgn0032198
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG4912 (de Morais Guedes et al., 2003, Lasko, 2000, Keleman et al., 2009.8.5, Perkins et al., 2009, Hughes et al., 2008, Cammarato et al., 2011) eEF1d (Jasper et al., 2002) eEF1delta (Giot et al., 2003, Loop et al., 2004, Japanese National Institute of Genetics, 2012.5.21) eEF1δ (Blanchette et al., 2005, )
Name Synonym	eEF1delta (Cammarato et al., 2011) eEF1δ
Secondary FlyBase IDs
References ( 29 )
Generate a list of	All references relating to this gene ( 29 )
List References by type	Research paper  ( 10 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 9 ) Stock list  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 3 )
	Crawford et al., 2012, Cell Death Differ. 19(12): 2040--2048 Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. [FBrf0220233] Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134 Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342] Spasic et al., 2012, PLoS Genet. 8(1): e1002433 Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm. [FBrf0217189] Show all research papers ...