• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\holn1

General Information
Symbol	Dmel\holn1	Species	D. melanogaster
Name	hole-in-one	Annotation symbol	CG5198
Feature type	protein_coding_gene	FlyBase ID	FBgn0032250
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	31E2-31E2	Sequence location	2L:10,435,995..10,437,316 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene hole-in-one is referred to in FlyBase by the symbol Dmel\holn1 (CG5198, FBgn0032250). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: chaeta development; wing disc development; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of wound healing; compound eye development; wound healing; phagocytosis, engulfment. 9 alleles are reported. The phenotypes of these alleles are annotated with: eye; trichogen cell; wing; scutellum. It has one annotated transcript and one annotated polypeptide. Protein features are: GYF. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval Malpighian tubules, larval salivary gland, adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1635365_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5198. Gene sequence location is 2L:10435995..10437316.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 31E2-31E2   Limits computationally determined from genome sequence between P{lacW}KdelRk00311 and P{lacW}l(2)k09116k09116&P{lacW}Fatpk10307
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\holn1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) holn1-RA FBtr0080026  NM_135560   1198   319
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein holn1-PA   FBpp0079616   36.8   319   4.52     NP_609404   AAF52953
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GYF (IPR003169)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52953   AI135860   AW940515   AY069127 AAL39272   BF485568   BF485761   BF491017   BI172843   BI240821   BI366116   BI482673   BT088782   CZ468039   CZ468040   CZ471291   EC057652   GH749864   GH752078   GH755543   GH756867   GH757931   GH774751   GH782847   GH785962   GH791483   GH793072   GH804868   GH805957   GH805981   GH810011   GH812948   GH814618   GH818843   GH823501   GH824297   GH829284   GH833982   GH835077   GH838766   GH840915   GH841903   GH842737   GH844456   GH850800   GH858467   GH861298   GH861713   GH864676   GH866743   GH867087   GH867122   GH869762   GH871342   GH872081   GH873955   GH877500   GH878048   GH879943   GH880920   GH881333   GH884184   GH884916   GH885423   GH886147   GH887369   GH889629   GH891102   GH898078   GH899703   GH901726   GH902786   GH905825   GH916495   GH917556   GH924839   GH929762   GH930851   GH932231
UniProtKB/Swiss-Prot	Q9VKV5
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
nucleus inferred from direct assay (Geiger et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval Malpighian tubules, larval salivary gland, adult ovary, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    164.475 Larval Midgut    57.2 Larval Hindgut    70 Larval Malpighian Tubules    151.8 Larval Fat Body    73.2 Larval Salivary Gland    127.5 Larval Trachea    91.925 Larval Carcass    70.825 Adult Head    71.5 Adult Eye    114 Adult Brain    95.9 Adult Thoracic-Abdominal Ganglion    93.1 Adult Crop    95.7 Adult Midgut    52.4 Adult Hindgut    54.9 Adult Malpighian Tubules    69 Adult Fat Body    72.5 Adult Salivary Gland    74.9 Adult Heart    71.375 Adult VirginFemale Spermatheca    50.8 Adult InseminatedFemale Spermatheca    54.1 Adult Ovary    254.4 Adult Testis    148.1 Adult Male Accessory Gland    74.2 Adult Carcass    66.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    71.5   NA  Eye    114   NA  Brain    95.9   164.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    93.1   NA  Crop    95.7   57.2  Midgut    52.4   70  Hindgut    54.9   151.8  Malpighian Tubules    69   73.2  Fat Body    72.5   127.5  Salivary Gland    74.9   NA  Heart    71.375   91.925  Trachea    NA   NA  VirginFemale Spermatheca    50.8   NA  InseminatedFemale Spermatheca    54.1   NA  Ovary    254.4   NA  Testis    148.1   NA  Male Accessory Gland    74.2   70.825  Carcass    66.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (45) central nervous system, larvae L3  (29) central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (83) testis, mated 4-day male  (44) accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (45) central nervous system, larvae L3  29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (83) testis, mated 4-day male  (44) accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    29 central nervous system, pupae P8    20 head, virgin 1-day female    13 head, virgin 4-day female    12 head, virgin 20-day female    5 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    17 head, mated 20-day male    20 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    12 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    7 fat body, larvae L3 wandering    8 fat body, white prepupae    24 fat body, pupae P8    23 carcass, larvae L3 wandering    22 carcass, 1-day adult    8 carcass, 4-day adult    14 carcass, 20-day adult    10 ovary, virgin 4-day female    54 ovary, mated 4-day female    83 testis, mated 4-day male    44 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (29) embryo 02-04hr  (48) embryo 04-06hr  (37) embryo 06-08hr    25 embryo 08-10hr  (27) embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  29 embryo 02-04hr  (48) embryo 04-06hr  (37) embryo 06-08hr    25 embryo 08-10hr  27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    48 embryo 04-06hr    37 embryo 06-08hr    25 embryo 08-10hr    27 embryo 10-12hr    21 embryo 12-14hr    24 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    6 embryo 20-22hr    19 embryo 22-24hr    20 larva L1    4 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    4 adult male 01day    8 adult male 05day    9 adult male 30day    6 adult female 01day    7 adult female 05day    20 adult female 30day    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (60) Schneider line 2 Sg4    20 embryonic 1182-4H  (30) embryonic GM2    21 embryonic Kc167  (44) embryonic S1  (34) embryonic S3    24 leg disc CME L1  (29) wing disc CME-W2  (30) wing disc ML-DmD8    22 wing disc ML-DmD9  (30) wing disc ML-DmD16-c3  (36) wing disc ML-DmD21  (44) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  (30) eye-antennal disc ML-DmD11  (34) antennal disc ML-DmD20-c5  (27) mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1  (43) CNS ML-DmBG2-c2  (29) tumorous blood cells mbn2    18 ovary fGS/OSS  (67) ovary OSC  (61) ovary OSS  (68) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (60) Schneider line 2 Sg4    20 embryonic 1182-4H  30 embryonic GM2    21 embryonic Kc167  (44) embryonic S1  (34) embryonic S3    24 leg disc CME L1  29 wing disc CME-W2  30 wing disc ML-DmD8    22 wing disc ML-DmD9  30 wing disc ML-DmD16-c3  (36) wing disc ML-DmD21  (44) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  30 eye-antennal disc ML-DmD11  (34) antennal disc ML-DmD20-c5  27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1  (43) CNS ML-DmBG2-c2  29 tumorous blood cells mbn2    18 ovary fGS/OSS  (67) ovary OSC  (61) ovary OSS  (68) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    60 Schneider line 2 Sg4    20 embryonic 1182-4H    30 embryonic GM2    21 embryonic Kc167    44 embryonic S1    34 embryonic S3    24 leg disc CME L1    29 wing disc CME-W2    30 wing disc ML-DmD8    22 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    44 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    34 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    23 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    18 ovary fGS/OSS    67 ovary OSC    61 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (32) cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult  (54) Copper 0.5 mM 12 hrs, larvae L3  26 Copper 15 mM 48 hrs, 4-day adult  (59) Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult  (33) Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (50) Caffeine 25 mg/ml 48 hrs, 4-day adult  (32) Paraquat 5 mM 48 hrs, 4-day adult  (39) Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult  (54) Copper 0.5 mM 12 hrs, larvae L3  26 Copper 15 mM 48 hrs, 4-day adult  (59) Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult  (33) Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (50) Caffeine 25 mg/ml 48 hrs, 4-day adult  32 Paraquat 5 mM 48 hrs, 4-day adult  (39) Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    32 cold shock, 4-day adult    22 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    23 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    54 Copper 0.5 mM 12 hrs, larvae L3    26 Copper 15 mM 48 hrs, 4-day adult    59 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    50 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    39 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_05 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032250 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5198-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal holn1c07150 holn1LL07287 lethal (with holn1c07150) holn1LL07287 lethal (with holn1LL07287) holn1c07150 lethal | pupal stage, with Scer\GAL4Act5C.PU holn1GD11573 holn1KK100428 viable, with Scer\GAL4pnr-MD237 holn1GD11573 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 holn1GD11573 wound healing defective | embryonic stage (with holn1c07150) holn1LL07287 wound healing defective | embryonic stage (with holn1LL07287) holn1c07150 wound healing defective | embryonic stage | recessive holn1c07150 holn1LL07287 Phenotype manifest in Allele eye holn1c07150 macrochaeta | ectopic holn1c07150 macrochaeta | ectopic, with Scer\GAL4Act5C.PU holn1GD11573 macrochaeta | supernumerary holn1c07150 macrochaeta | supernumerary, with Scer\GAL4Act5C.PU holn1GD11573 scutellum holn1c07150 scutellum, with Scer\GAL4Act5C.PU holn1GD11573 trichogen cell, with Scer\GAL4pnr-MD237 holn1GD11573 wing, with Scer\GAL4Bx-MS1096 holn1KK100428 holn1GD11573 wing vein | ectopic, with Scer\GAL4Bx-MS1096 holn1KK100428 holn1GD11573
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of holn1 Class Mutagen Stocks Known lesion holn1c07150 piggyBac transposase 2 Yes holn1c02576 piggyBac transposase 1 -- holn1LL07287 1 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of holn1 Class Mutagen Stocks Known lesion holn1GD11573 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes holn1HMS01882 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes holn1KK100428 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes holn1NIG.5198R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes holn1Scer\UAS.P\T.cGa in vitro construct - regulatory fusion 0 Yes holn1Scer\UAS.P\T.GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.5198R} NA P{TRiP.HMS01882} NA P{UASp-holn1.G} NA P{UASp-holn1.GFP} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}holn1c02576 NA PBac{PB}holn1c07150 NA PBac{SAstopDsRed}holn1LL07287 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
	There is no information supporting a molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
chaeta development inferred from mutant phenotype (Geiger et al., 2011) compound eye development inferred from mutant phenotype (Geiger et al., 2011) phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006) positive regulation of epidermal growth factor receptor signaling pathway inferred from genetic interaction with Ras85D (Geiger et al., 2011) inferred from mutant phenotype (Geiger et al., 2011) positive regulation of wound healing inferred from mutant phenotype (Geiger et al., 2011) wing disc development inferred from mutant phenotype (Geiger et al., 2011) wound healing inferred from mutant phenotype (Campos et al., 2010)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Geiger et al., 2011)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
holn1 - CG12320 experimental knowledge based (Guruharsha et al., 2011) holn1 - CG6674 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) holn1 - dome anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) holn1 - ecd experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions holn1 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0032250 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34432
Orthologs
OrthoDB Orthologs (39) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69CQTQ Dipteran inclusive ortholog search EOG6JDHGT Insect inclusive ortholog search EOG6SJ4BD Arthropod inclusive ortholog search EOG60ZPF2 Metazoa inclusive ortholog search EOG6Z0Q1N
Orthologs in Drosophila Species (EOG69CQTQ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\holn1     Drosophila simulans   Dsim\GD23703 Y   Drosophila sechellia   Dsec\GM18415 Y   Drosophila erecta   Dere\GG10134 Y   Drosophila yakuba   Dyak\GE18946 Y   Drosophila ananassae   Dana\GF15791 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18730 Y   Drosophila persimilis   Dper\GL19140 Y   Drosophila willistoni   Dwil\GK15260 Y   Drosophila virilis   Dvir\GJ14592 Y   Drosophila mojavensis   Dmoj\GI18162 Y   Drosophila grimshawi   Dgri\GH13298 Y
Orthologs in non-Drosophila Dipterans (EOG6JDHGT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002976   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011793   Anopheles gambiae Malaria mosquito  Agam\AGAP011494   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ010290
Orthologs in non-Dipteran Insects (EOG6SJ4BD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB53829   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006893   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15049   Atta cephalotes Leafcutter ant  Acep\ACEP27159   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20316   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15608   Linepithema humile Argentine ant  Lhum\LH24831   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23066   Solenopsis invicta Red fire ant  Sinv\SINV14241   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008069   Bombyx mori Silkmoth  Bmor\BGIBMGA003699   Pediculus humanus Human body louse  Phum\PHUM415070   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07221
Orthologs in non-Insect Arthropods (EOG60ZPF2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_188546   Ixodes scapularis Deer tick  Isca\ISCW020736
Orthologs in non-Arthropod Metazoa (EOG6Z0Q1N)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\teg-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023519gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023520gn   Danio rerio Zebrafish  Drer\cd2bp2   Xenopus tropicalis Western clawed frog  Xtro\clip4   Mus musculus House mouse  Mmus\Cd2bp2   Rattus norvegicus Norway rat  Rnor\Cd2bp2   Homo sapiens Human  Hsap\CD2BP2
Human Orthologs (1)
Gene OMIM HGNC Hsap\CD2BP2
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23703 Drosophila sechellia Dsec\GM18415 Drosophila erecta Dere\GG10134 Drosophila yakuba Dyak\GE18946 Drosophila ananassae Dana\GF15791 Drosophila pseudoobscura pseudoobscura Dpse\GA18730 Drosophila persimilis Dper\GL19140 Drosophila willistoni Dwil\GK15260 Drosophila virilis Dvir\GJ14592 Drosophila mojavensis Dmoj\GI18162 Drosophila grimshawi Dgri\GH13298
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	17802 w1118; PBac{PB}holn1c07150/CyO 38968 y1 sc* v1; P{TRiP.HMS01882}attP2
Harvard	- PBac{PB}holn1c02576 - PBac{PB}holn1c07150
Kyoto	142008 y* w*; PBac{SAstopDsRed}holn1LL07287 P{neoFRT}40A P{FRT(whs)}G13 cn1 bw1 / CyO, S* bw1
VDRC	v27369 w1118; P{GD11573}v27369 v27370 w1118; P{GD11573}v27370
Genomic Clones ( 2 )
	BACR34C10 BACR48K04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 72 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH13760
Other clones	FI06493
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT19606 AT19805 AT27666 RE15533 RE37754 RE51571 RE65390
Other clones	CK01.38A.D5 RP003005006 RP003016855 RP003020261 RP003027990 RP003058776 RP003081784 RP003087415 RP003105261 RP003123393 RP003129532 RP003133453 RP003139679 RP003154410 RP003156538 RP003191784 RP003203151 RP003219598 RP003220335 RP003228612 RP003229857 RP003242630 RP003260569 RP003261012 RP003270095 RP003280696 RP003281373 RP003284765 RP003292509 RP003296683 RP003310470 RP003315454 RP003337752 RP003341167 RP003359648 RP003373828 RP003375328 RP003398461 RP003413585 RP003413814 RP003416095 RP003425510 RP003428326 RP003445418 RP003448758 RP003466128 RP003480653 RP003485421 RP003489401 RP003490771 RP003500013 RP003506804 RP003509791 RP003523530 RP003525289 RP003528704 RP003535189 RP003550983 RP003555389 RP003555843 RP003584685 RP003598041 RP003645092
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032250 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34432
Antibody Information
Other Information
Discoverer
Etymology
	Named 'hole-in-one' in honor of the wound healing defect attributed to the mutant holn1[c07150]. (Geiger et al., 2011)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: holn1 CG5198 (Geiger et al., 2011)
Source for database merge of
Additional comments
Other Comments
	S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135560 RefSeq (Proteins) • NP_609404 DDBJ / EMBL / GenBank • AAF52953 AAL39272 AI135860 AW940515 AY069127 CZ468039 CZ468040 CZ471291 Entrez Gene - A searchable database of RefSeq genes. • 34432 UniProtKB/Swiss-Prot • Q9VKV5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GYF (IPR003169)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0032250 DRSC - Results from RNAi screens. • FBgn0032250 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032250 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5198-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032250 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34432 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34432 modMine - Data generated by the modENCODE project. • FBgn0032250
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG5198 (Stroschein-Stevenson et al., 2006, Geiger et al., 2011, Keleman et al., 2009.8.5, Campos et al., 2010, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1) holn1 (Geiger et al., 2011)
Name Synonym	hole-in-one (Geiger et al., 2011, )
Secondary FlyBase IDs
References ( 19 )
Research paper	Crawford et al., 2012, Cell Death Differ. 19(12): 2040--2048 Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. [FBrf0220233] Geiger et al., 2011, PLoS ONE 6(11): e28349 Hole-in-One Mutant Phenotypes Link EGFR/ERK Signaling to Epithelial Tissue Repair in Drosophila. [FBrf0216857] Campos et al., 2010, Genetics 184(1): 129--140 Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. [FBrf0209682] Stroschein-Stevenson et al., 2006, PLoS Biol. 4(1): e4 Identification of Drosophila gene products required for phagocytosis of Candida albicans. [FBrf0191376]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]