General Information Symbol Dmel\ CycYSpecies D. melanogaster Name Cyclin Y Annotation symbol CG14939 Feature type protein_coding_gene FlyBase ID FBgn0032378 Gene Model Status Current Stock availability 6 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 33A2-33A2 Sequence location 2L:11,810,092..11,813,780 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Cyclin Y is referred to in FlyBase by the symbol
Dmel\CycY (CG14939, FBgn0032378). It is a protein_coding_gene from
Drosophila melanogaster . An electronic pipeline based on InterPro domains suggests that it has the
molecular function : protein kinase binding. There is experimental evidence that it is involved in the
biological process : developmental growth.
7 alleles are reported . No phenotypic data is available. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Cyclin Y; Cyclin, N-terminal; Cyclin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636868_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CycY. Gene sequence location is
2L:11810092..11813780 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.46
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
525.85
Larval Midgut
202
Larval Hindgut
285.7
Larval Malpighian Tubules
376.2
Larval Fat Body
173.7
Larval Salivary Gland
170.8
Larval Trachea
283.85
Larval Carcass
261.825
Adult Head
132.9
Adult Eye
144.825
Adult Brain
243.2
Adult Thoracic-Abdominal Ganglion
260.8
Adult Crop
192.5
Adult Midgut
98.8
Adult Hindgut
120.6
Adult Malpighian Tubules
205.4
Adult Fat Body
197.6
Adult Salivary Gland
113.9
Adult Heart
186.65
Adult VirginFemale Spermatheca
116.9
Adult InseminatedFemale Spermatheca
125
Adult Ovary
233.4
Adult Testis
87.9
Adult Male Accessory Gland
110.5
Adult Carcass
100.4
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
132.9
NA
Eye
144.825
NA
Brain
243.2
525.85
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
260.8
NA
Crop
192.5
202
Midgut
98.8
285.7
Hindgut
120.6
376.2
Malpighian Tubules
205.4
173.7
Fat Body
197.6
170.8
Salivary Gland
113.9
NA
Heart
186.65
283.85
Trachea
NA
NA
VirginFemale Spermatheca
116.9
NA
InseminatedFemale Spermatheca
125
NA
Ovary
233.4
NA
Testis
87.9
NA
Male Accessory Gland
110.5
261.825
Carcass
100.4
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(45)
central nervous system, larvae L3
(70)
central nervous system, pupae P8
(53)
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
(28)
head, mated 20-day male
(29)
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
(29)
fat body, pupae P8
(30)
carcass, larvae L3 wandering
(42)
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
(63)
ovary, mated 4-day female
(49)
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(45)
central nervous system, larvae L3
(70)
central nervous system, pupae P8
(53)
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
(42)
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
(63)
ovary, mated 4-day female
(49)
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
70
central nervous system, pupae P8
53
head, virgin 1-day female
22
head, virgin 4-day female
20
head, virgin 20-day female
17
head, mated 1-day female
19
head, mated 4-day female
17
head, mated 20-day female
16
head, mated 1-day male
26
head, mated 4-day male
28
head, mated 20-day male
29
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
26
digestive system, 1-day adult
20
digestive system, 4-day adult
19
digestive system, 20-day adult
19
fat body, larvae L3 wandering
15
fat body, white prepupae
29
fat body, pupae P8
30
carcass, larvae L3 wandering
42
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
17
ovary, virgin 4-day female
63
ovary, mated 4-day female
49
testis, mated 4-day male
21
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(58)
embryo 02-04hr
(82)
embryo 04-06hr
(71)
embryo 06-08hr
(63)
embryo 08-10hr
(61)
embryo 10-12hr
(63)
embryo 12-14hr
(46)
embryo 14-16hr
(50)
embryo 16-18hr
(38)
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
(29)
larva L2
(28)
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
(29)
larva L3 puffstage 7-9
(33)
white prepupae new
(35)
white prepupae 12hr
(37)
white prepupae 24hr
(45)
pupae 2d postWPP
(33)
pupae 3d postWPP
(27)
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
(30)
adult female 05day
(38)
adult female 30day
(39)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(58)
embryo 02-04hr
(82)
embryo 04-06hr
(71)
embryo 06-08hr
(63)
embryo 08-10hr
(61)
embryo 10-12hr
(63)
embryo 12-14hr
(46)
embryo 14-16hr
(50)
embryo 16-18hr
(38)
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
(33)
white prepupae new
(35)
white prepupae 12hr
(37)
white prepupae 24hr
(45)
pupae 2d postWPP
(33)
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
(38)
adult female 30day
(39)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
58
embryo 02-04hr
82
embryo 04-06hr
71
embryo 06-08hr
63
embryo 08-10hr
61
embryo 10-12hr
63
embryo 12-14hr
46
embryo 14-16hr
50
embryo 16-18hr
38
embryo 18-20hr
25
embryo 20-22hr
22
embryo 22-24hr
22
larva L1
29
larva L2
28
larva L3 12hr old
25
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
29
larva L3 puffstage 7-9
33
white prepupae new
35
white prepupae 12hr
37
white prepupae 24hr
45
pupae 2d postWPP
33
pupae 3d postWPP
27
pupae 4d postWPP
20
adult male 01day
17
adult male 05day
18
adult male 30day
18
adult female 01day
30
adult female 05day
38
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(105)
Schneider line 2 Sg4
(93)
embryonic 1182-4H
(83)
embryonic GM2
(78)
embryonic Kc167
(84)
embryonic S1
(77)
embryonic S3
(80)
leg disc CME L1
(84)
wing disc CME-W2
(78)
wing disc ML-DmD8
(53)
wing disc ML-DmD9
(84)
wing disc ML-DmD16-c3
(59)
wing disc ML-DmD21
(101)
wing disc ML-DmD32
(77)
haltere disc ML-DmD17-c3
(84)
eye-antennal disc ML-DmD11
(62)
antennal disc ML-DmD20-c5
(87)
mixed discs ML-DmD4-c1
(88)
CNS ML-DmBG1-c1
(55)
CNS ML-DmBG2-c2
(105)
tumorous blood cells mbn2
(88)
ovary fGS/OSS
(49)
ovary OSC
(45)
ovary OSS
(36)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(105)
Schneider line 2 Sg4
(93)
embryonic 1182-4H
(83)
embryonic GM2
(78)
embryonic Kc167
(84)
embryonic S1
(77)
embryonic S3
(80)
leg disc CME L1
(84)
wing disc CME-W2
(78)
wing disc ML-DmD8
(53)
wing disc ML-DmD9
(84)
wing disc ML-DmD16-c3
(59)
wing disc ML-DmD21
(101)
wing disc ML-DmD32
(77)
haltere disc ML-DmD17-c3
(84)
eye-antennal disc ML-DmD11
(62)
antennal disc ML-DmD20-c5
(87)
mixed discs ML-DmD4-c1
(88)
CNS ML-DmBG1-c1
(55)
CNS ML-DmBG2-c2
(105)
tumorous blood cells mbn2
(88)
ovary fGS/OSS
(49)
ovary OSC
(45)
ovary OSS
(36)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
105
Schneider line 2 Sg4
93
embryonic 1182-4H
83
embryonic GM2
78
embryonic Kc167
84
embryonic S1
77
embryonic S3
80
leg disc CME L1
84
wing disc CME-W2
78
wing disc ML-DmD8
53
wing disc ML-DmD9
84
wing disc ML-DmD16-c3
59
wing disc ML-DmD21
101
wing disc ML-DmD32
77
haltere disc ML-DmD17-c3
84
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
87
mixed discs ML-DmD4-c1
88
CNS ML-DmBG1-c1
55
CNS ML-DmBG2-c2
105
tumorous blood cells mbn2
88
ovary fGS/OSS
49
ovary OSC
45
ovary OSS
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(27)
cold shock, 4-day adult
19
heat shock, 4-day adult
(28)
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
(27)
Cadmium 100 mM 48 hrs, 4-day adult
(40)
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
(35)
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
(43)
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(39)
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
(35)
Paraquat 10 mM 48 hrs, 4-day adult
(34)
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
(40)
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
(35)
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
(43)
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(39)
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
(35)
Paraquat 10 mM 48 hrs, 4-day adult
(34)
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
27
cold shock, 4-day adult
19
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
26
Cadmium 50 mM 12 hrs, larvae L3
22
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
40
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
35
Zinc 5 mM 12 hrs, larvae L3
18
Zinc 4.5 mM 48 hrs, 4-day adult
23
Ethanol 2.5% 3 hrs, larvae L3
43
Ethanol 5% 3 hrs, larvae L3
24
Ethanol 10% 3 hrs, larvae L3
24
Caffeine 1.5 mg/ml 4 hrs, larvae L3
21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
39
Caffeine 25 mg/ml 48 hrs, 4-day adult
20
Paraquat 5 mM 48 hrs, 4-day adult
35
Paraquat 10 mM 48 hrs, 4-day adult
34
Rotenone 2 μg 12 hrs, larvae L3
24
Rotenone 8 μg 12 hrs, larvae L3
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 2 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 5 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 1 term ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores.
Orthologs
OrthoDB Orthologs (45)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6QZ85Z )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6ZGPN2 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6MKMBZ )
Apis mellifera
Western honey bee
Amel\GB41975
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG002713
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH11955
Atta cephalotes
Leafcutter ant
Acep\ACEP23647
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO18405
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL20618
Linepithema humile
Argentine ant
Lhum\LH24391
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB16545
Solenopsis invicta
Red fire ant
Sinv\SINV16008
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6RR500 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6BPD5K )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (3)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 6 )Bloomington VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 92 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: CycY CG14939
Source for database merge of Source for merge of: CG14939 anon-WO0118547.165
Additional comments Source for merge of CG14939 anon-WO0118547.165 was sequence comparison (date:051113).
Other Comments Area matching Drosophila ESTS AA979442 and AA392418 (inverted).
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
- A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores.
Synonyms & Secondary IDs
( 7 )Reported As Symbol Synonym CG14939
(
Liu and Finley, 2010 ,
Liu and Finley, 2007 ,
Liu and Finley, 2008 ,
Keleman et al., 2009.8.5 ,
Davidson et al., 2009 ,
Ni et al., 2010.12.1 )
Name Synonym Secondary FlyBase
IDs References ( 22 )Generate a list of List References by type
Recent research papers (0)
All research papers listed in FlyBase were published before 2011