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Gene Dmel\CG5325

General Information
Symbol	Dmel\CG5325	Species	D. melanogaster
Name		Annotation symbol	CG5325
Feature type	protein_coding_gene	FlyBase ID	FBgn0032407
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	33C4-33C4	Sequence location	2L:12,093,771..12,095,250 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5325 (FBgn0032407). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: nervous system development. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Pex19 protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult midgut, larval Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass. Gene sequence location is 2L:12093771..12095250.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References Mast et al., 2011, Dis. Model Mech. 4(5): 659--672 Sequence features BKN28370 HFA02839
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 33C4-33C4   Limits computationally determined from genome sequence between P{EP}JhI-21EP1187 and P{lacW}Aats-thrk04203
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5325 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5325-RA FBtr0080326  NM_135703   1208   292 CG5325-RB FBtr0080327  NM_164991   1274   172
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5325-PA   FBpp0079908   31.3   292   3.94     NP_609547   AAF53161 CG5325-PB   FBpp0079909   18.2   172   3.82     NP_723722   AAN10802
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Pex19 protein (IPR006708)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696446   AA938857   AE014134 AAF53161   AE014134 AAN10802   AI063330   AI294300   AW941396   AY069294 AAL39439   BG637458   BG640488   BI216370   BI230495   BI353346   BI354705   BI361911   BI362416   BI369702   BI563361   BI565100   BI566817   BI570944   BI571062   BI573111   BI574907   BI583476   BI587501   BI590810   BI590813   BI610954   BI611384   BI615923   BI619261   BI625429   BI625531   BI626020   BI627691   BI635501   BI636712   BP554199   BT009961 AAQ22430   CO153788   CO284163   EC199666   EC250233   EC264580   EL884028   EL884029   GH943651   GH946644   GH949313   GH966537   GH969239   GH979599   GH983998
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IP97 Q8T9H4 Q9VKB5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032407    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032407 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032407 expression level Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3740) embryo 02-04hr  (4555) embryo 04-06hr  (4455) embryo 06-08hr  (3697) embryo 08-10hr  (3966) embryo 10-12hr  (6709) embryo 12-14hr  (4481) embryo 14-16hr  (4836) embryo 16-18hr  (5473) embryo 18-20hr  (6739) embryo 20-22hr  (6554) embryo 22-24hr  (5583) larva L1  (6523) larva L2  (7334) larva L3 12hr old  (6520) larva L3 puffstage 1-2  (3270) larva L3 puffstage 3-6  (2629) larva L3 puffstage 7-9  (2585) white prepupae new  (2264) white prepupae 12hr  (2288) white prepupae 24hr  (2782) pupae 2d postWPP  (4097) pupae 3d postWPP  (6694) pupae 4d postWPP  (3538) adult male 01day  (3776) adult male 05day  (4383) adult male 30day  (3300) adult female 01day  (3410) adult female 05day  (3422) adult female 30day  (3881) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3740) embryo 02-04hr  (4555) embryo 04-06hr  (4455) embryo 06-08hr  (3697) embryo 08-10hr  (3966) embryo 10-12hr  (6709) embryo 12-14hr  (4481) embryo 14-16hr  (4836) embryo 16-18hr  (5473) embryo 18-20hr  (6739) embryo 20-22hr  (6554) embryo 22-24hr  (5583) larva L1  (6523) larva L2  (7334) larva L3 12hr old  (6520) larva L3 puffstage 1-2  (3270) larva L3 puffstage 3-6  (2629) larva L3 puffstage 7-9  (2585) white prepupae new  (2264) white prepupae 12hr  (2288) white prepupae 24hr  (2782) pupae 2d postWPP  (4097) pupae 3d postWPP  (6694) pupae 4d postWPP  (3538) adult male 01day  (3776) adult male 05day  (4383) adult male 30day  (3300) adult female 01day  (3410) adult female 05day  (3422) adult female 30day  (3881) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032407 expression level Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3740) embryo 02-04hr  (4555) embryo 04-06hr  (4455) embryo 06-08hr  (3697) embryo 08-10hr  (3966) embryo 10-12hr  (6709) embryo 12-14hr  (4481) embryo 14-16hr  (4836) embryo 16-18hr  (5473) embryo 18-20hr  (6739) embryo 20-22hr  (6554) embryo 22-24hr  (5583) larva L1  (6523) larva L2  (7334) larva L3 12hr old  (6520) larva L3 puffstage 1-2  (3270) larva L3 puffstage 3-6  (2629) larva L3 puffstage 7-9  (2585) white prepupae new  (2264) white prepupae 12hr  (2288) white prepupae 24hr  (2782) pupae 2d postWPP  (4097) pupae 3d postWPP  (6694) pupae 4d postWPP  (3538) adult male 01day  (3776) adult male 05day  (4383) adult male 30day  (3300) adult female 01day  (3410) adult female 05day  (3422) adult female 30day  (3881) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3740) embryo 02-04hr  (4555) embryo 04-06hr  (4455) embryo 06-08hr  (3697) embryo 08-10hr  (3966) embryo 10-12hr  (6709) embryo 12-14hr  (4481) embryo 14-16hr  (4836) embryo 16-18hr  (5473) embryo 18-20hr  (6739) embryo 20-22hr  (6554) embryo 22-24hr  (5583) larva L1  (6523) larva L2  (7334) larva L3 12hr old  (6520) larva L3 puffstage 1-2  (3270) larva L3 puffstage 3-6  (2629) larva L3 puffstage 7-9  (2585) white prepupae new  2264 white prepupae 12hr  2288 white prepupae 24hr  (2782) pupae 2d postWPP  (4097) pupae 3d postWPP  (6694) pupae 4d postWPP  (3538) adult male 01day  (3776) adult male 05day  (4383) adult male 30day  (3300) adult female 01day  (3410) adult female 05day  (3422) adult female 30day  (3881) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3740 embryo 02-04hr    4555 embryo 04-06hr    4455 embryo 06-08hr    3697 embryo 08-10hr    3966 embryo 10-12hr    6709 embryo 12-14hr    4481 embryo 14-16hr    4836 embryo 16-18hr    5473 embryo 18-20hr    6739 embryo 20-22hr    6554 embryo 22-24hr    5583 larva L1    6523 larva L2    7334 larva L3 12hr old    6520 larva L3 puffstage 1-2    3270 larva L3 puffstage 3-6    2629 larva L3 puffstage 7-9    2585 white prepupae new    2264 white prepupae 12hr    2288 white prepupae 24hr    2782 pupae 2d postWPP    4097 pupae 3d postWPP    6694 pupae 4d postWPP    3538 adult male 01day    3776 adult male 05day    4383 adult male 30day    3300 adult female 01day    3410 adult female 05day    3422 adult female 30day    3881 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032407    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032407 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult midgut, larval Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032407 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5325-RB;CG5325-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5325GD11608 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG5325 Class Mutagen Stocks Known lesion CG5325DP00474 1 -- CG5325EY21383 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5325 Class Mutagen Stocks Known lesion CG5325GD11608 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5325KK108370 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6032 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11608} NA P{KK108370} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG5325EY21383 NA P{Mae-UAS.6.11}CG5325DP00474 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
nervous system development inferred from mutant phenotype (Koizumi et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
peroxisome inferred from electronic annotation with InterPro:IPR006708 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5325 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60681 DroID - A comprehensive database of gene and protein interactions. • FBgn0032407 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34630
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21559 Dere\GG23764 Dgri\GH11575 Dmoj\GI17065 Dper\GL16215 Dpse\GA18805 Dsec\GM26722 Dsim\GD23815 Dvir\GJ17649 Dwil\GK21085 Dyak\GE18569
Curated drosophilid orthologs	Dpse\GA18805
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004985-PB Aedes aegypti (mosquito) AGAP008804-PA Anopheles gambiae (mosquito) XP_001944784.1 Acyrthosiphon pisum (pea aphid) At5g17550.1 Arabidopsis thaliana (wall cress) 27170 Batrachochytrium dendrobatidis (chytrid fungus) 121162 Branchiostoma floridae (lancelet) BGIBMGA011144-PA Bombyx mori (silk worm) ENSBTAP00000009921 Bos taurus (bovine) CAL0002188 Candida albicans (a form of yeast) CN01312 Caenorhabditis brenneri (small nematode) CBP01755 Caenorhabditis briggsae (nematode) CE00201 Caenorhabditis elegans (worm) ENSCAFP00000018441 Canis familiaris (dog) ENSCINP00000029689 Ciona intestinalis (sea squirt) JA05353 Caenorhabditis japonica (nematode) CMQ019C Cyanidioschyzon merolae (red alga) cn04328 Cryptococcus neoformans (yeast-like fungus) CPIJ009284 Culex pipens (mosquito) ENSCPOP00000013441 Cavia porcellus (guinea pig) 154271 Chlamidomonas reinhardtii (green alga) RP16505 Caenorhabditis remanei (nematode) 224754 Capitella spl (polychaete worm) DEHA2A11308g Debaryomyces Hansenii (yeast) 305007 Daphnia pulex (daphnia) ENSDARP00000025585 Danio rerio (zebra fish) ENSECAP00000022218 Equus caballus (horse) ENSGACP00000023478 Gymnopilus aculeatus (mushroom) 166500 Hypsipyla robusta (cedar shoot borer) ENSP00000357051 Homo sapiens (human) ISCW020698-PA Ixodes scapularis (deer tick) 185973 Lottia gigantea (owl limpet) ENSMODP00000011961 Monodelphis domestica (gray opossum) ENSMMUP00000028774 Macaca mulatta (rhesus monkey) ENSMUSP00000075289 Mus musculus (house mouse) 243581 Nematostella vectensis (starlet anemone) XP_001605956.1 Nasonia vitripennis (wasp) ENSOANP00000004580 Ornithorynchus anatinus (platypus) ENSORLP00000003683 Oryzias latipes (japanese killifish) LOC_Os02g44220.1 Oryza sativa (asian rice) PHUM000863-PA Pediculus humanus (human body louse) ENSPPYP00000000743 Pongo pygmaeus (orangutan) 77483 Phytophthora ramorum (sudden oak death pathogen) 144082 Phytophthora sojae (root rot pathogen) 836295 Populus trichocarpa (black cottonwood) ENSPTRP00000051676 Pan troglodytes (chimpanzee) ENSRNOP00000032453 Rattus norvegicus (norway rat) ENSRNOP00000051153 Rattus norvegicus (norway rat) 4884556 Sorghum bicolor (sorghum) XP_001182021.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001198742.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001202600.1 Strongylocentrotus purpuratus (purple sea urchin) XP_968216.1 Tribolium castaneum (red flour beetle) ENSTRUP00000027089 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000017783 Xenopus tropicalis (frog) YALI0B22660g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18214 NV10147 LH10650 ISCW020698 FBgn0235977 FBgn0223077 FBgn0204818 FBgn0195185 FBgn0181575 JGI_V11_305007 FBgn0078805 FBgn0153819 FBgn0139810 FBgn0119055 FBgn0115903 FBgn0098559 CPIJ009284 BGIBMGA011144 ACYPI002803 GB18587 AGAP008804 AAEL004985 PHUM569130 GLEAN_15168
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	22476 y1 w67c23; P{EPgy2}CG5325EY21383 22055 y1 w67c23; P{Mae-UAS.6.11}CG5325DP00474
VDRC	v100746 P{KK108370}VIE-260B v22064 w1118; P{GD11608}v22064
Genomic Clones ( 1 )
	BACR02B06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 48 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM14611 RH04488
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03076 GM07704 GM23216 GM27973 LP07638 RE14183 RE23488 RE46320 RE46964 RE55968 RH04485 RH05744 RH05872 RH08817 RH16990 RH17583 RH22096 RH27456 RH28189 RH33986 RH36567 RH45824 RH50261 RH62790 RH65845 RH65977 RH66544 RH69065 SD11516 SD15464 SD16869 SD18516
Other clones	46399 173818 287463 EK165413 EN02823 FGM228E11 IP15402 RP004188077 RP004203126 RP004217983 RP004248277 RP004248883 RP004444113 RP004479468
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032407 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34630
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG5325 BEST:GH03076 (Rana, 2004.7.8)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135703 NM_164991 RefSeq (Proteins) • NP_609547 NP_723722 DDBJ / EMBL / GenBank • AA938857 AAF53161 AAL39439 AAN10802 AAQ22430 AI063330 AW941396 AY069294 BI590813 BT009961 Entrez Gene - A searchable database of RefSeq genes. • 34630 UniProtKB/TrEMBL • Q8IP97 Q8T9H4 Q9VKB5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Pex19 protein (IPR006708)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60681 DroID - A comprehensive database of gene and protein interactions. • FBgn0032407 DRSC - Results from RNAi screens. • FBgn0032407 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032407 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5325-RB;CG5325-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032407 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34630 InParanoid A subset of ortholog calls from InParanoid. • AAEL004985-PB Aedes aegypti (mosquito) AGAP008804-PA Anopheles gambiae (mosquito) XP_001944784.1 Acyrthosiphon pisum (pea aphid) At5g17550.1 Arabidopsis thaliana (wall cress) 27170 Batrachochytrium dendrobatidis (chytrid fungus) 121162 Branchiostoma floridae (lancelet) BGIBMGA011144-PA Bombyx mori (silk worm) ENSBTAP00000009921 Bos taurus (bovine) CAL0002188 Candida albicans (a form of yeast) CN01312 Caenorhabditis brenneri (small nematode) CBP01755 Caenorhabditis briggsae (nematode) CE00201 Caenorhabditis elegans (worm) ENSCAFP00000018441 Canis familiaris (dog) ENSCINP00000029689 Ciona intestinalis (sea squirt) JA05353 Caenorhabditis japonica (nematode) CMQ019C Cyanidioschyzon merolae (red alga) cn04328 Cryptococcus neoformans (yeast-like fungus) CPIJ009284 Culex pipens (mosquito) ENSCPOP00000013441 Cavia porcellus (guinea pig) 154271 Chlamidomonas reinhardtii (green alga) RP16505 Caenorhabditis remanei (nematode) 224754 Capitella spl (polychaete worm) DEHA2A11308g Debaryomyces Hansenii (yeast) 305007 Daphnia pulex (daphnia) ENSDARP00000025585 Danio rerio (zebra fish) ENSECAP00000022218 Equus caballus (horse) ENSGACP00000023478 Gymnopilus aculeatus (mushroom) 166500 Hypsipyla robusta (cedar shoot borer) ENSP00000357051 Homo sapiens (human) ISCW020698-PA Ixodes scapularis (deer tick) 185973 Lottia gigantea (owl limpet) ENSMODP00000011961 Monodelphis domestica (gray opossum) ENSMMUP00000028774 Macaca mulatta (rhesus monkey) ENSMUSP00000075289 Mus musculus (house mouse) 243581 Nematostella vectensis (starlet anemone) XP_001605956.1 Nasonia vitripennis (wasp) ENSOANP00000004580 Ornithorynchus anatinus (platypus) ENSORLP00000003683 Oryzias latipes (japanese killifish) LOC_Os02g44220.1 Oryza sativa (asian rice) PHUM000863-PA Pediculus humanus (human body louse) ENSPPYP00000000743 Pongo pygmaeus (orangutan) 77483 Phytophthora ramorum (sudden oak death pathogen) 144082 Phytophthora sojae (root rot pathogen) 836295 Populus trichocarpa (black cottonwood) ENSPTRP00000051676 Pan troglodytes (chimpanzee) ENSRNOP00000032453 Rattus norvegicus (norway rat) ENSRNOP00000051153 Rattus norvegicus (norway rat) 4884556 Sorghum bicolor (sorghum) XP_001182021.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001198742.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001202600.1 Strongylocentrotus purpuratus (purple sea urchin) XP_968216.1 Tribolium castaneum (red flour beetle) ENSTRUP00000027089 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000017783 Xenopus tropicalis (frog) YALI0B22660g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34630 modMine - Data generated by the modENCODE project. • FBgn0032407 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18214 NV10147 LH10650 ISCW020698 FBgn0235977 FBgn0223077 FBgn0204818 FBgn0195185 FBgn0181575 JGI_V11_305007 FBgn0078805 FBgn0153819 FBgn0139810 FBgn0119055 FBgn0115903 FBgn0098559 CPIJ009284 BGIBMGA011144 ACYPI002803 GB18587 AGAP008804 AAEL004985 PHUM569130 GLEAN_15168
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BEST:GH03076   CG5325 (Koizumi et al., 2007, Keleman et al., 2009.8.5, Spresser et al., 2008)
Name Synonym	Peroxisomal farnesylated protein (Kang et al., 2002)
Secondary FlyBase IDs
	FBgn0066310
References ( 18 )
Research paper	Mast et al., 2011, Dis. Model Mech. 4(5): 659--672 A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders. [FBrf0215017] Spresser et al., 2008, J. Genet. 87(2): 109--117 Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity. [FBrf0205982] Koizumi et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104(13): 5626--5631 RNA interference screen to identify genes required for Drosophila embryonic nervous system development. [FBrf0200690] Inlow and Restifo, 2004, Genetics 166(2): 835--881 Molecular and comparative genetics of mental retardation. [FBrf0174714] Kang et al., 2002, Proc. Natl. Acad. Sci. USA 99(2): 838--843 Life extension in Drosophila by feeding a drug. [FBrf0145208]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Levis, 2009.8.13, Release 5 sequence localizations for HP and DP lines. Release 5 sequence localizations for HP and DP lines. [FBrf0208533] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bellen, 2006.8.3, MBBatch686_2.xml MBBatch686_2.xml [FBrf0191805] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Rana, 2004.7.8, BLAST analysis. BLAST analysis. [FBrf0178762] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]