• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG9426

General Information
Symbol	Dmel\CG9426	Species	D. melanogaster
Name		Annotation symbol	CG9426
Feature type	protein_coding_gene	FlyBase ID	FBgn0032485
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	34A10-34A10	Sequence location	2L:13,216,290..13,219,923 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9426 (FBgn0032485). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process: cytoplasmic sequestering of transcription factor. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: BTB/Kelch-associated; BTB/POZ; BTB/POZ fold; BTB/POZ-like; Galactose oxidase, beta-propeller; Kelch repeat type 1; Kelch-like protein, gigaxonin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1626888_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9426. Gene sequence location is 2L:13216290..13219923.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Controlled Vocabulary Terms regulation of cell cycle
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 34A10-34A10   Limits computationally determined from genome sequence between P{lacW}l(2)k11328k11328&P{lacW}l(2)k10105k10105 and P{EP}EP850&P{lacW}l(2)k05911k05911
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9426 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9426-RA FBtr0080484  NM_135772   3184   627
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9426-PA   FBpp0080063   69.2   627   5.09     NP_609616   AAF53261
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Kelch repeat type 1 (IPR006652) BTB/Kelch-associated (IPR011705) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Kelch-like protein, gigaxonin (IPR017096) Galactose oxidase, beta-propeller (IPR015916)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA942078   AE014134 AAF53261   AI063459   AI256922   AI546610   AY118728 AAM50588   BF486069   BF491311   BF492256   BF492350   BF499848   BI163410   BI163634   BI168884   BI371687   BI372455   BI633266   BI635507   BP547133   BP547593   BP550533   BP550534   CL528077   CO179895   CO180074   CO268766   CO268921   CO297725   CO298875   CO310572   CO326273   CO337383   CO340527   CO342453   CZ488278   CZ488279   EC064691   EC074129   EC085441   EC197178   EC208668   EC223389   EC253071   EC257059   EC260500   EC264288   ES693080
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VK21
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 13 -- 16   embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    398.825 Larval Midgut    80.8 Larval Hindgut    219.4 Larval Malpighian Tubules    168.7 Larval Fat Body    145.6 Larval Salivary Gland    234.7 Larval Trachea    182.55 Larval Carcass    161.525 Adult Head    186.2 Adult Eye    194.925 Adult Brain    363.4 Adult Thoracic-Abdominal Ganglion    310 Adult Crop    178 Adult Midgut    64.3 Adult Hindgut    176.7 Adult Malpighian Tubules    164.9 Adult Fat Body    105.8 Adult Salivary Gland    274 Adult Heart    149.925 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    170.6 Adult Ovary    303 Adult Testis    125.1 Adult Male Accessory Gland    210.9 Adult Carcass    84.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    186.2   NA  Eye    194.925   NA  Brain    363.4   398.825  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    310   NA  Crop    178   80.8  Midgut    64.3   219.4  Hindgut    176.7   168.7  Malpighian Tubules    164.9   145.6  Fat Body    105.8   234.7  Salivary Gland    274   NA  Heart    149.925   182.55  Trachea    NA   NA  VirginFemale Spermatheca    135   NA  InseminatedFemale Spermatheca    170.6   NA  Ovary    303   NA  Testis    125.1   NA  Male Accessory Gland    210.9   161.525  Carcass    84.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female  (31) ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female  31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    18 central nervous system, pupae P8    20 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    11 head, mated 20-day male    11 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    24 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    8 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    4 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    31 ovary, mated 4-day female    24 testis, mated 4-day male    17 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (42) embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day  (28) adult female 30day  (29) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (42) embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day  28 adult female 30day  29 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    8 embryo 04-06hr    4 embryo 06-08hr    8 embryo 08-10hr    11 embryo 10-12hr    18 embryo 12-14hr    14 embryo 14-16hr    12 embryo 16-18hr    11 embryo 18-20hr    9 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    7 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    20 white prepupae new    22 white prepupae 12hr    23 white prepupae 24hr    22 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    15 adult female 01day    16 adult female 05day    28 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3  (38) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2  (32) tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3  (38) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2  32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    25 Schneider line 2 Sg4    25 embryonic 1182-4H    14 embryonic GM2    21 embryonic Kc167    21 embryonic S1    13 embryonic S3    12 leg disc CME L1    13 wing disc CME-W2    21 wing disc ML-DmD8    21 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    24 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    18 ovary fGS/OSS    5 ovary OSC    6 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    6 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_02 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • RE02793 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032485 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9426-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG9426 Stages(s) 4-6 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG9426EY08011 viable, with Scer\GAL4pnr-MD237 CG9426GD4403 Sterility Allele fertile CG9426EY08011 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG9426 Class Mutagen Stocks Known lesion CG9426EY08011 P-element activity 1 -- CG9426f05662 piggyBac transposase 1 -- CG9426NP5220 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9426 Class Mutagen Stocks Known lesion CG9426GD4403 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9426HMS01860 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9426JF01594 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9426KK102397 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9426NIG.9426R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel8029 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4403} NA P{KK102397} NA P{NIG.9426R} NA P{TRiP.HMS01860} NA P{TRiP.JF01594} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG9426EY08011 NA miscellaneous insertions PBac{WH}CG9426f05662 NA insertion of enhancer trap binary system P{ET-QF}ET10 No P{GawB}CG9426NP5220 No
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
regulation of cell cycle inferred from direct assay (Guest et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
actin binding inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Biological Process
CV term Evidence References
cytoplasmic sequestering of transcription factor inferred from sequence or structural similarity with UniProtKB:Q9Z2X8 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytoplasm inferred from sequence or structural similarity with UniProtKB:Q9Z2X8 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG9426 - Cul-3 two hybrid (Arama et al., 2007)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9426 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60757 DroID - A comprehensive database of gene and protein interactions. • FBgn0032485 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34719
Orthologs
OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG60VW84 Dipteran inclusive ortholog search EOG670TRG Insect inclusive ortholog search EOG6DR87F Arthropod inclusive ortholog search EOG64MW73 Metazoa inclusive ortholog search EOG6TXQJW
Orthologs in Drosophila Species (EOG60VW84)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG9426     Drosophila sechellia   Dsec\GM25768 Y   Drosophila erecta   Dere\GG10220 Y   Drosophila yakuba   Dyak\GE11820 Y   Drosophila ananassae   Dana\GF15622 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21778 Y   Drosophila persimilis   Dper\GL26698 Y   Drosophila willistoni   Dwil\GK15571 Y   Drosophila virilis   Dvir\GJ18276 Y   Drosophila virilis   Dvir\GJ14910     Drosophila mojavensis   Dmoj\GI10727 Y   Drosophila grimshawi   Dgri\GH10638 Y
Orthologs in non-Drosophila Dipterans (EOG670TRG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003701   Anopheles gambiae Malaria mosquito  Agam\AGAP009913   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802403
Orthologs in non-Dipteran Insects (EOG6DR87F)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB53654   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG032519   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20022   Atta cephalotes Leafcutter ant  Acep\ACEP27669   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19716   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17136   Linepithema humile Argentine ant  Lhum\LH21250   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25893   Solenopsis invicta Red fire ant  Sinv\SINV12880   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006802   Bombyx mori Silkmoth  Bmor\BGIBMGA006864   Tribolium castaneum Red flour beetle  Tcas\TC012628
Orthologs in non-Insect Arthropods (EOG64MW73)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW018081
Orthologs in non-Arthropod Metazoa (EOG6TXQJW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028892gn   Danio rerio Zebrafish  Drer\ENSDARG00000075339   Danio rerio Zebrafish  Drer\zgc:171487   Xenopus tropicalis Western clawed frog  Xtro\ipp   Gallus gallus Domestic chicken  Ggal\IPP   Mus musculus House mouse  Mmus\Ipp   Rattus norvegicus Norway rat  Rnor\Ipp   Homo sapiens Human  Hsap\IPP
Human Orthologs (1)
Gene OMIM HGNC Hsap\IPP
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM25768 Drosophila erecta Dere\GG10220 Drosophila yakuba Dyak\GE11820 Drosophila ananassae Dana\GF15622 Drosophila pseudoobscura pseudoobscura Dpse\GA21778 Drosophila persimilis Dper\GL26698 Drosophila willistoni Dwil\GK15571 Drosophila virilis Dvir\GJ18276 Drosophila mojavensis Dmoj\GI10727 Drosophila grimshawi Dgri\GH10638
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	31121 y1 v1; P{TRiP.JF01594}attP2 16422 y1 w67c23; P{EPgy2}CG9426EY08011 38946 y1 sc* v1; P{TRiP.HMS01860}attP2
Harvard	- PBac{WH}CG9426f05662
VDRC	v103746 P{KK102397}VIE-260B v10843 w1118; P{GD4403}v10843/CyO
Genomic Clones ( 2 )
	BACR04E19 BACR32O12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 41 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH03286
Other clones	DPiM_GH03286
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT14614 AT20220 AT28023 AT29163 AT29278 LD26108 LP03674 RE02793 RE03076 RE09770 RE58625 RE59420 SD08071 SD16875 SD27311
Other clones	54668 57066 60886 99410 214347.1 297946 CK01.121A.G7 CK01.126D.D2 EC00463 EC00863 EC253071 EC257059 EK092628 EK093101 EK170421 EK174027 EK222034 EN14422 EP03544 EP10828 EP14937 FGH113G07 FGH118F04 FGM207F11
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032485 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34719
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Pilot et al., 2006) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135772 RefSeq (Proteins) • NP_609616 DDBJ / EMBL / GenBank • AAF53261 AAM50588 AI063459 AY118728 CL528077 CZ488278 CZ488279 Entrez Gene - A searchable database of RefSeq genes. • 34719 UniProtKB/TrEMBL • Q9VK21
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Kelch repeat type 1 (IPR006652) BTB/Kelch-associated (IPR011705) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Kelch-like protein, gigaxonin (IPR017096) Galactose oxidase, beta-propeller (IPR015916) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE02793
Linkouts
	BioGRID - A database of protein and genetic interactions • 60757 DroID - A comprehensive database of gene and protein interactions. • FBgn0032485 DRSC - Results from RNAi screens. • FBgn0032485 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032485 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9426-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032485 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34719 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34719 modMine - Data generated by the modENCODE project. • FBgn0032485
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG9426 (Pilot et al., 2006, Bakal et al., 2007, Arama et al., 2007, Keleman et al., 2009.8.5, Potter et al., 2010, Ni et al., 2008, Guest et al., 2011, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1, Soshnev et al., 2012) Ipp (Arama et al., 2007)
Name Synonym
Secondary FlyBase IDs
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 2 )
	Soshnev et al., 2012, Nucleic Acids Res. 40(12): 5415--5431 Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. [FBrf0218724] Guest et al., 2011, BMC Syst. Biol. 5(1): 65 A protein network-guided screen for cell cycle regulators in Drosophila. [FBrf0213913] Show all research papers ...