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Gene Dmel\CG16812

General Information
Symbol	Dmel\CG16812	Species	D. melanogaster
Name		Annotation symbol	CG16812
Feature type	protein_coding_gene	FlyBase ID	FBgn0032488
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	34A10-34A10	Sequence location	2L:13,222,561..13,224,550 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG16812 (FBgn0032488). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Sterile alpha motif domain; Sterile alpha motif/pointed domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1623176_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG16812. Gene sequence location is 2L:13222561..13224550.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Knowles-Barley, 2011.8.24, BrainTrap expression curation.
FB2012_01	Sequence features BKN24436 HFA02519
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 34A10-34A10   Limits computationally determined from genome sequence between P{lacW}l(2)k11328k11328&P{lacW}l(2)k10105k10105 and P{EP}EP850&P{lacW}l(2)k05911k05911
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG16812 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG16812-RA FBtr0080445  NM_135775   1752   455
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG16812-PA   FBpp0080025   49.9   455   10.67     NP_609619   AAF53264
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sterile alpha motif domain (IPR001660) Sterile alpha motif/pointed domain (IPR013761)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202253   AA390952   AA540026   AA802896   AA940890   AA949435   AA978989   AE014134 AAF53264   AI259700   AI456810   AI456815   AI518031   AW943361   AY058662 AAL13891   BF488562   BF491367   BF503273   BG634751   BG637132   BG641314   BI141783   BI169209   BI212882   BI214613   BI214694   BI216592   BI243510   BI371266   BI487059   BI580127   BI635430   CO178864   CO278244   CO283427   CO299179   CO303108   CO303613   CO317149   CO318027   CO319978   EC058353   EC061111   EC067109   EC084958   EC086496   EC204129   EC214397   EC222031   EC237579   EC250030
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VK18
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032488    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032488 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032488 expression level Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3392) embryo 02-04hr  (5334) embryo 04-06hr  (4591) embryo 06-08hr  (3681) embryo 08-10hr  (3394) embryo 10-12hr  (3161) embryo 12-14hr  (1920) embryo 14-16hr  (1620) embryo 16-18hr  (1548) embryo 18-20hr  (851) embryo 20-22hr  (1786) embryo 22-24hr  (1618) larva L1  (803) larva L2  (780) larva L3 12hr old  (675) larva L3 puffstage 1-2  (610) larva L3 puffstage 3-6  (822) larva L3 puffstage 7-9  (1067) white prepupae new  (1170) white prepupae 12hr  (1198) white prepupae 24hr  (1513) pupae 2d postWPP  (1305) pupae 3d postWPP  (890) pupae 4d postWPP  (617) adult male 01day  (935) adult male 05day  (1147) adult male 30day  (1009) adult female 01day  (985) adult female 05day  (1817) adult female 30day  (1923) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3392) embryo 02-04hr  (5334) embryo 04-06hr  (4591) embryo 06-08hr  (3681) embryo 08-10hr  (3394) embryo 10-12hr  (3161) embryo 12-14hr  (1920) embryo 14-16hr  (1620) embryo 16-18hr  (1548) embryo 18-20hr    851 embryo 20-22hr  (1786) embryo 22-24hr  (1618) larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr  (1513) pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day  (1817) adult female 30day  (1923) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032488 expression level Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3392) embryo 02-04hr  (5334) embryo 04-06hr  (4591) embryo 06-08hr  (3681) embryo 08-10hr  (3394) embryo 10-12hr  (3161) embryo 12-14hr  (1920) embryo 14-16hr  (1620) embryo 16-18hr  (1548) embryo 18-20hr  (851) embryo 20-22hr  (1786) embryo 22-24hr  (1618) larva L1  (803) larva L2  (780) larva L3 12hr old  (675) larva L3 puffstage 1-2  (610) larva L3 puffstage 3-6  (822) larva L3 puffstage 7-9  (1067) white prepupae new  (1170) white prepupae 12hr  (1198) white prepupae 24hr  (1513) pupae 2d postWPP  (1305) pupae 3d postWPP  (890) pupae 4d postWPP  (617) adult male 01day  (935) adult male 05day  (1147) adult male 30day  (1009) adult female 01day  (985) adult female 05day  (1817) adult female 30day  (1923) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3392) embryo 02-04hr  (5334) embryo 04-06hr  (4591) embryo 06-08hr  (3681) embryo 08-10hr  (3394) embryo 10-12hr  (3161) embryo 12-14hr  1920 embryo 14-16hr  1620 embryo 16-18hr  1548 embryo 18-20hr    851 embryo 20-22hr  1786 embryo 22-24hr  1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr  1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day  1817 adult female 30day  1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3392 embryo 02-04hr    5334 embryo 04-06hr    4591 embryo 06-08hr    3681 embryo 08-10hr    3394 embryo 10-12hr    3161 embryo 12-14hr    1920 embryo 14-16hr    1620 embryo 16-18hr    1548 embryo 18-20hr    851 embryo 20-22hr    1786 embryo 22-24hr    1618 larva L1    803 larva L2    780 larva L3 12hr old    675 larva L3 puffstage 1-2    610 larva L3 puffstage 3-6    822 larva L3 puffstage 7-9    1067 white prepupae new    1170 white prepupae 12hr    1198 white prepupae 24hr    1513 pupae 2d postWPP    1305 pupae 3d postWPP    890 pupae 4d postWPP    617 adult male 01day    935 adult male 05day    1147 adult male 30day    1009 adult female 01day    985 adult female 05day    1817 adult female 30day    1923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032488    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032488 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032488 expression level Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032488 expression level Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    261.5 Larval Midgut    70.9 Larval Hindgut    108.5 Larval Malpighian Tubules    96.3 Larval Fat Body    116.9 Larval Salivary Gland    129.2 Larval Trachea    121.1 Larval Carcass    99.25 Adult Head    116.2 Adult Eye    106.425 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    179.8 Adult Crop    127.5 Adult Midgut    99.1 Adult Hindgut    117.6 Adult Malpighian Tubules    100.9 Adult Fat Body    77.6 Adult Salivary Gland    112.9 Adult Heart    64.725 Adult VirginFemale Spermatheca    99.8 Adult InseminatedFemale Spermatheca    103.2 Adult Ovary    260.4 Adult Testis    197.2 Adult Male Accessory Gland    200 Adult Carcass    88.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    116.2   NA  Eye    106.425   NA  Brain    177.5   261.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    179.8   NA  Crop    127.5   70.9  Midgut    99.1   108.5  Hindgut    117.6   96.3  Malpighian Tubules    100.9   116.9  Fat Body    77.6   129.2  Salivary Gland    112.9   NA  Heart    64.725   121.1  Trachea    NA   NA  VirginFemale Spermatheca    99.8   NA  InseminatedFemale Spermatheca    103.2   NA  Ovary    260.4   NA  Testis    197.2   NA  Male Accessory Gland    200   99.25  Carcass    88.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032488 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16812-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG16812GD6566 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG16812 Class Mutagen Stocks Known lesion CG16812CPTI000342 piggyBac transposase 0 Yes CG16812CPTI001660 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG16812 Class Mutagen Stocks Known lesion CG16812GD6566 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG16812KK105300 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel8029 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6566} NA P{KK105300} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{602.P.SVS-1}CG16812CPTI000342 NA PBac{681.P.FSVS-1}CG16812CPTI001660 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG16812 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60760 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0032488 DroID - A comprehensive database of gene and protein interactions. • FBgn0032488 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34722
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23064 Dere\GG23824 Dgri\GH25088 Dmoj\GI17609 Dper\GL26307 Dpse\GA14162 Dsec\GM10268 Dsim\GD23873 Dvir\GJ17954 Dwil\GK14546 Dyak\GE18627
Curated drosophilid orthologs	Dpse\GA14162
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001638-PA Aedes aegypti (mosquito) AGAP007811-PA Anopheles gambiae (mosquito) XP_001948858.1 Acyrthosiphon pisum (pea aphid) 117827 Branchiostoma floridae (lancelet) 125822 Branchiostoma floridae (lancelet) BGIBMGA013515-PA Bombyx mori (silk worm) CN20369 Caenorhabditis brenneri (small nematode) CBP07147 Caenorhabditis briggsae (nematode) CE17859 Caenorhabditis elegans (worm) ENSCAFP00000008008 Canis familiaris (dog) CPIJ000860 Culex pipens (mosquito) ENSCPOP00000012396 Cavia porcellus (guinea pig) 262091 Daphnia pulex (daphnia) ENSGACP00000012917 Gymnopilus aculeatus (mushroom) 189105 Hypsipyla robusta (cedar shoot borer) ENSP00000350556 Homo sapiens (human) 234914 Lottia gigantea (owl limpet) ENSMODP00000009503 Monodelphis domestica (gray opossum) ENSMMUP00000011729 Macaca mulatta (rhesus monkey) ENSMUSP00000066803 Mus musculus (house mouse) 239680 Nematostella vectensis (starlet anemone) XP_001607201.1 Nasonia vitripennis (wasp) ENSOANP00000028021 Ornithorynchus anatinus (platypus) ENSORLP00000008383 Oryzias latipes (japanese killifish) PHUM007771-PA Pediculus humanus (human body louse) ENSPPYP00000011180 Pongo pygmaeus (orangutan) ENSPTRP00000018855 Pan troglodytes (chimpanzee) ENSRNOP00000024829 Rattus norvegicus (norway rat) Smp_123340 Schistosoma mansoni (trematode parasite) XP_796860.2 Strongylocentrotus purpuratus (purple sea urchin) 57123 Trichoplax adhaerens (metazoa) ENSTNIP00000010553 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027011 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000036932 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14655 NV10258 LH10963 FBgn0236032 FBgn0216552 FBgn0205121 FBgn0195243 FBgn0165219 JGI_V11_262091 FBgn0074191 FBgn0163889 FBgn0140353 FBgn0132543 FBgn0129719 FBgn0115963 FBgn0100058 CPIJ000860 CPIJ015983 CPIJ000630 CPIJ013526 CPIJ007410 CPIJ018615 CPIJ018246 CPIJ005365 CPIJ016274 BGIBMGA013515 ACYPI006007 GB16996 AGAP007811 AAEL001638 PHUM230740
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v102840 P{KK105300}VIE-260B v14971 w1118; P{GD6566}v14971 v14972 w1118; P{GD6566}v14972
Genomic Clones ( 2 )
	BACR04E19 BACR32O12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 47 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD36945
Other clones	DPiM_LD36945
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT19227 AT24028 AT28092 AT31066 GM06534 LD02402 LD09757 LD19351 LD23211 LD29441 LD33221 LD36953 LD37432 LP03173 RE10316 RE18138 RE20573 RE20693 RE23785 RE41171 RE58126 RE70564 RE74267 SD12633 SD14993 SD15796 SD16782
Other clones	17428 37556 43870 70753 120192 163200 165380 176736 CK01.73B.G7 EK057819 EK129428 EK163147 EK174701 EK240027 EK242227 EK267219 EK270037 EK281630
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032488 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34722
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135775 RefSeq (Proteins) • NP_609619 DDBJ / EMBL / GenBank • AAF53264 AAL13891 AI456810 AW943361 AY058662 Entrez Gene - A searchable database of RefSeq genes. • 34722 UniProtKB/TrEMBL • Q9VK18
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sterile alpha motif domain (IPR001660) Sterile alpha motif/pointed domain (IPR013761)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60760 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0032488 DroID - A comprehensive database of gene and protein interactions. • FBgn0032488 DRSC - Results from RNAi screens. • FBgn0032488 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032488 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16812-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032488 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34722 InParanoid A subset of ortholog calls from InParanoid. • AAEL001638-PA Aedes aegypti (mosquito) AGAP007811-PA Anopheles gambiae (mosquito) XP_001948858.1 Acyrthosiphon pisum (pea aphid) 117827 Branchiostoma floridae (lancelet) 125822 Branchiostoma floridae (lancelet) BGIBMGA013515-PA Bombyx mori (silk worm) CN20369 Caenorhabditis brenneri (small nematode) CBP07147 Caenorhabditis briggsae (nematode) CE17859 Caenorhabditis elegans (worm) ENSCAFP00000008008 Canis familiaris (dog) CPIJ000860 Culex pipens (mosquito) ENSCPOP00000012396 Cavia porcellus (guinea pig) 262091 Daphnia pulex (daphnia) ENSGACP00000012917 Gymnopilus aculeatus (mushroom) 189105 Hypsipyla robusta (cedar shoot borer) ENSP00000350556 Homo sapiens (human) 234914 Lottia gigantea (owl limpet) ENSMODP00000009503 Monodelphis domestica (gray opossum) ENSMMUP00000011729 Macaca mulatta (rhesus monkey) ENSMUSP00000066803 Mus musculus (house mouse) 239680 Nematostella vectensis (starlet anemone) XP_001607201.1 Nasonia vitripennis (wasp) ENSOANP00000028021 Ornithorynchus anatinus (platypus) ENSORLP00000008383 Oryzias latipes (japanese killifish) PHUM007771-PA Pediculus humanus (human body louse) ENSPPYP00000011180 Pongo pygmaeus (orangutan) ENSPTRP00000018855 Pan troglodytes (chimpanzee) ENSRNOP00000024829 Rattus norvegicus (norway rat) Smp_123340 Schistosoma mansoni (trematode parasite) XP_796860.2 Strongylocentrotus purpuratus (purple sea urchin) 57123 Trichoplax adhaerens (metazoa) ENSTNIP00000010553 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027011 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000036932 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34722 modMine - Data generated by the modENCODE project. • FBgn0032488 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14655 NV10258 LH10963 FBgn0236032 FBgn0216552 FBgn0205121 FBgn0195243 FBgn0165219 JGI_V11_262091 FBgn0074191 FBgn0163889 FBgn0140353 FBgn0132543 FBgn0129719 FBgn0115963 FBgn0100058 CPIJ000860 CPIJ015983 CPIJ000630 CPIJ013526 CPIJ007410 CPIJ018615 CPIJ018246 CPIJ005365 CPIJ016274 BGIBMGA013515 ACYPI006007 GB16996 AGAP007811 AAEL001638 PHUM230740
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG16812 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	FlyProt project., 2011.8.8, CPTI protein trap lines available from the Kyoto Stock Center. CPTI protein trap lines available from the Kyoto Stock Center. [FBrf0214588] Knowles-Barley, 2011.8.24, BrainTrap expression curation. BrainTrap expression curation. [FBrf0215202] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]