FlyBase Gene Report: Dmel\Prosα6T

General Information

Symbol

Dmel\Prosα6T

Species

D. melanogaster

Name

Proteasome α6 subunit, Testis-specific

Annotation Symbol

CG5648

Feature Type

protein_coding_gene

FlyBase ID

FBgn0032492

Gene Model Status

Current

Stock Availability

4 publicly available

Gene Snapshot

Proteasome α6 subunit, Testis-specific (Prosα6T) encodes a testes-specific subunit of the 26S proteasome. [Date last reviewed: 2019-08-01]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

34A11-34A11

Sequence location

2L:13,232,039..13,233,058 [+]

Recombination map

2-47

RefSeq locus

NT_033779 REGION:13232039..13233058

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (14 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables endopeptidase activity

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

enables threonine-type endopeptidase activity

inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in defense response to Gram-negative bacterium

inferred from high throughput mutant phenotype

(Cronin et al., 2009)

involved_in negative regulation of innate immune response

inferred from high throughput mutant phenotype

(Cronin et al., 2009)

involved_in sperm individualization

inferred from mutant phenotype

(Zhong and Belote, 2007)

involved_in spermatid nucleus elongation

inferred from mutant phenotype

(Zhong and Belote, 2007)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in proteasomal ubiquitin-independent protein catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in proteasome-mediated ubiquitin-dependent protein catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Zhong and Belote, 2007)

located_in cytosol

inferred from direct assay

(Ma et al., 2002)

located_in male germ cell nucleus

inferred from direct assay

(Ma et al., 2002)

located_in nucleus

inferred from direct assay

(Zhong and Belote, 2007)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of proteasome core complex, alpha-subunit complex

inferred from biological aspect of ancestor with PANTHER:PTN000175095

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of proteasome core complex

inferred from biological aspect of ancestor with PANTHER:PTN000174701

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

PROTEASOME ALPHA SUBUNITS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

PROTEASOME ALPHA SUBUNITS -: The 26S proteasome degrades polyubiquitinated proteins in the cytoplasm and nucleus. It is formed from a cylindrical catalytic core 20S proteasome capped at each end by a regulatory 19S particle. The 19S regulatory particle recognizes, unfolds, and translocates ubiquitinated proteins into the catalytic core particle in an ATP-dependent manner. The core particle is a highly conserved, barrel-shaped complex composed of four stacked heptameric rings. Narrow substrate entry channels are created by the two outer rings, which are each formed by seven alpha subunits. (Adapted from FBrf0215459 and PMID:28583440).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Prosα6T for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

retrotransposed_protein_coding_gene

(dos Santos, 2014, Bai et al., 2007, Langille and Clark, 2007)

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Prosα6T-RA

FBtr0080448

NM_135779

1020

289

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Prosα6T-PA

FBpp0080028

31.9

289

4.67

NP_609623

AAF53268

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VK14

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Prosα6T using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Prosalpha6T_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

spermatogenesis & adult stage | male

testis | restricted

(Vedelek et al., 2018)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Zhong and Belote, 2007)

located_in cytosol

inferred from direct assay

(Ma et al., 2002)

located_in male germ cell nucleus

inferred from direct assay

(Ma et al., 2002)

located_in nucleus

inferred from direct assay

(Zhong and Belote, 2007)

Expression Deduced from Reporters

Reporter: P{Prosα6T-EGFP.M}

Stage

Tissue/Position (including subcellular localization)

Reference

spermatogenesis

spermatid

(Ma et al., 2002)

spermatozoon

• sperm flagellum

(Ma et al., 2002)

adult stage | male

spermatid cyst

(Zhong and Belote, 2007)

elongation stage spermatid

(Zhong and Belote, 2007)

individualization stage spermatid

(Zhong and Belote, 2007)

spermatozoon

(Zhong and Belote, 2007)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Prosα6T in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Prosα6T

View exonic expression by tissue for Dmel\Prosα6T

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0032492

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG5648-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5648

Flygut - An atlas of the Drosophila adult midgut

FBgn0032492

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Prosα6T

Transgenic constructs containing regulatory region of Prosα6T

Deletions and Duplications ( 2 )

Disrupted in

Df(2L)ED784

(Zhong and Belote, 2007)

Df(2L)Exel8029

(Ryder, 2004.4.26)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

Prosα6T¹

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Prosα6T^GD11719

viable, with Scer\GAL4^Mef2.PR

Prosα6T^GD11719

viable, with Scer\GAL4^pnr-MD237

Prosα6T^GD11719

viable, with Scer\GAL4^tin.CΔ4

Prosα6T^GD11719

Sterility

Allele

male sterile (with Df(2L)ED784)

Prosα6T¹

male sterile | recessive

Prosα6T¹

Phenotype manifest in

Allele

cystic bulge

Prosα6T¹

nucleus & elongation stage spermatid

Prosα6T¹

spermatozoon

Prosα6T¹

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (16)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\PSMA1

15 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (17)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Psma1

15 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (15)

Rnor\Psma1

13 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (15)

Xtro\psma1

6 of 12

Yes

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (20)

Drer\psma1

13 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (12)

Cele\pas-6

14 of 15

Yes

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Arabidopsis thaliana (thale-cress) (13)

Atha\PAF1

9 of 9

Yes

Atha\PAF2

9 of 9

Yes

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

1 of 9

Saccharomyces cerevisiae (Brewer's yeast) (11)

Scer\PRE5

14 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC6G10.04c

11 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190CSM )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA19030

Drosophila persimilis

Dper\GL26311

Drosophila willistoni

Dwil\GK14549

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915091M )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17011491

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02578

Mayetiola destructor

Hessian fly

Mdes\Mdes016490

Mayetiola destructor

Hessian fly

Mdes\Mdes010051

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL015007

Anopheles gambiae

Malaria mosquito

Agam\AGAP010253

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000897

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W09YK )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA009234

Danaus plexippus

Monarch butterfly

Dple\DPOGS213746-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL013910

Apis florea

Little honeybee

Aflo\3886037924

Apis mellifera

Western honey bee

Amel\LOC552654

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP13500

Bombus terrestris

Buff-tailed bumblebee

Bter\15204506

Linepithema humile

Argentine ant

Lhum\LH19254

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0015a6

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG005369

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_07881

Tribolium castaneum

Red flour beetle

Tcas\TC000258

Pediculus humanus

Human body louse

Phum\PHUM005720

Rhodnius prolixus

Kissing bug

Rpro\RPRC007220

Cimex lectularius

Bed bug

Clec\CLEC001842

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI005674

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05170

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X08QV )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR005012

Strigamia maritima

European centipede

Smar\SMAR012860

Ixodes scapularis

Black-legged tick

Isca\ISCW010978

Stegodyphus mimosarum

African social velvet spider

Smim\KFM81604.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur30g00340

Tetranychus urticae

Two-spotted spider mite

Turt\tetur30g00350

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_308807

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0DNK )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Psma1

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000005222

Gallus gallus

Domestic chicken

Ggal\PSMA1

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (24)

Gene Symbol

Score

Source

Alignment

8 of 10

4 of 10

4 of 10

4 of 10

4 of 10

4 of 10

4 of 10

4 of 10

4 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

3 of 10

2 of 10

2 of 10

2 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PSMA1; proteasome 20S subunit alpha 1

15 of 15

602854

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Prosα6T - Prosβ2

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Prosα6T

suppressible

Prosα6

(Zhong and Belote, 2007)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

60764

DroID - A comprehensive database of gene and protein interactions.

FBgn0032492

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

34726

MIST (protein-protein) - An integrated Molecular Interaction Database

Prosalpha6T

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Proteasome

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-47

Cytogenetic map

34A11-34A11

Sequence location

2L:13,232,039..13,233,058 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

34A11-34A11

Limits computationally determined from genome sequence between P{lacW}l(2)k11328^k11328&P{lacW}l(2)k10105^k10105 and P{EP}EP850&P{lacW}l(2)k05911^k05911

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-47

(FlyBase, 2016)

2-43.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (4)

Bloomington

55243

y¹ sc^* v¹ sev²¹; P{TRiP.HMC02418}attP2

FlyORF

F001622

M{UAS-Prosα6T.ORF}ZH-86Fb

F001162

M{UAS-Prosα6T.ORF.3xHA}ZH-86Fb

VDRC

v35023

w¹¹¹⁸; P{GD11719}v35023

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (7)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

AT30494

Other clones

DPiM_AT30494

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0032492

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

IP13219

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0032492

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34726

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Prosα6T CG5648

(FlyBase, 1996-)

Source for database merge of

Additional comments

The nomenclature of genes encoding subunits of the 26S proteasome of D. melanogaster have been standardized according to FBrf0215459. These symbols/names largely follow those used already in FlyBase, and largely mirror fly community usage. HOWEVER, note that at least one other nomenclature system exists that is followed by the HUGO Gene Nomenclature Committee (HGNC), for example, with the unfortunate result that several D. melanogaster genes have shared synonyms.

(FlyBase, 2009-)

The Prosα6T gene may have been derived from the Pros35 gene by retroposition.

(Bai et al., 2007)

The Prosα6T gene may have been derived from the Prosα6 gene by retroposition.

(Langille and Clark, 2007)

Source for identity of Prosα6T CG5648 was sequence comparison ( date:021115 ).

(FlyBase, 1996-)

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 71 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34726

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VK14

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0032492

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Prosalpha6T_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5648

Flygut - An atlas of the Drosophila adult midgut

FBgn0032492

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34726

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC000258

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG5648

modMine - A data warehouse for the modENCODE project

FBgn0032492

Linkouts

BioGRID - A database of protein and genetic interactions.

60764

DPiM - Drosophila Protein interaction map

FBgn0032492

DroID - A comprehensive database of gene and protein interactions.

FBgn0032492

DRSC - Results frm RNAi screens

FBgn0032492

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0032492

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG5648-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0032492

FlyMine - An integrated database for Drosophila genomics

FBgn0032492

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

34726

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Proteasome

MIST (protein-protein) - An integrated Molecular Interaction Database

Prosalpha6T

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

5648

(Ravi et al., 2009)

Alpha6T

(Bader et al., 2010)

CG5648

(Schertel et al., 2013, Ni et al., 2010.12.1, Belote and Zhong, 2009, Barbash and Lorigan, 2007, Zhong and Belote, 2007, Ma et al., 2002)

Prosalpha6T

(Vedelek et al., 2018, dos Santos, 2014, Schertel et al., 2013, Wasbrough et al., 2010, Wasbrough et al., 2010, Cronin et al., 2009, Bai et al., 2007, Barbash and Lorigan, 2007, Langille and Clark, 2007, Langille and Clark, 2007, Giot et al., 2003, Ma, 2002.9.3)

Prosα6T

(Meltzer et al., 2019, Fabian and Brill, 2012, Belote and Zhong, 2009, Yun et al., 2008, Bai et al., 2007, Bai et al., 2007, Stuart et al., 2007, Zhong and Belote, 2007, Ma et al., 2002)

prosα6T

(Sorourian and Betrán, 2008)

α6T

(Belote and Zhong, 2009)

Name Synonyms

Prosα6T

Proteasome alpha6T subunit

(Wasbrough et al., 2010)

Proteasome α6 subunit, Testis-specific

Proteasome α6T subunit

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

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