• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG16888

General Information
Symbol	Dmel\CG16888	Species	D. melanogaster
Name		Annotation symbol	CG16888
Feature type	protein_coding_gene	FlyBase ID	FBgn0032533
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	34D1-34D1	Sequence location	2L:13,812,698..13,813,256 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG16888 (FBgn0032533). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1638220_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG16888. Gene sequence location is 2L:13812698..13813256.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 34D1-34D1   Limits computationally determined from genome sequence between P{lacW}CG7364k07245 and P{lacW}Sosk05224&P{lacW}RpII33k05605
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG16888 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG16888-RA FBtr0080572  NM_135834   559   169
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG16888-PA   FBpp0080149   19.5   169   11.24     NP_609678   AAF53335
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53335   BE978520   BP548575   BT022654   CO295351   EC247550   EL877019
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VJW0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    7.925 Larval Midgut    6 Larval Hindgut    4.5 Larval Malpighian Tubules    6.3 Larval Fat Body    28.5 Larval Salivary Gland    13.7 Larval Trachea    6.6 Larval Carcass    6.575 Adult Head    4.7 Adult Eye    2 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    1.7 Adult Crop    6.2 Adult Midgut    8.3 Adult Hindgut    4.6 Adult Malpighian Tubules    5.8 Adult Fat Body    1.3 Adult Salivary Gland    11.4 Adult Heart    0.625 Adult VirginFemale Spermatheca    6.3 Adult InseminatedFemale Spermatheca    5 Adult Ovary    3.5 Adult Testis    356.1 Adult Male Accessory Gland    11.2 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4.7   NA  Eye    2   NA  Brain    4.1   7.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1.7   NA  Crop    6.2   6  Midgut    8.3   4.5  Hindgut    4.6   6.3  Malpighian Tubules    5.8   no informative data  Fat Body    1.3   no informative data  Salivary Gland    no informative data   NA  Heart    0.625   6.6  Trachea    NA   NA  VirginFemale Spermatheca    6.3   NA  InseminatedFemale Spermatheca    5   NA  Ovary    3.5   NA  Testis    356.1   NA  Male Accessory Gland    no informative data   6.575  Carcass    3.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    123 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8  (36) carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  (123) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  (123) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    123 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    123 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8  (36) carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  (123) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  123 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    36 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    3 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    123 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1  (47) embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9  (40) wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1  (43) CNS ML-DmBG2-c2    13 tumorous blood cells mbn2  (38) ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1  (47) embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9  (40) wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1  (43) CNS ML-DmBG2-c2    13 tumorous blood cells mbn2  (38) ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    3 embryonic 1182-4H    4 embryonic GM2    4 embryonic Kc167    2 embryonic S1    47 embryonic S3    0 leg disc CME L1    4 wing disc CME-W2    11 wing disc ML-DmD8    11 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    1 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    13 eye-antennal disc ML-DmD11    21 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    43 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    38 ovary fGS/OSS    14 ovary OSC    18 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    3 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_28 mE1_20_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032533 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16888-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG16888GD9224 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG16888 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG16888 Class Mutagen Stocks Known lesion CG16888GD9224 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG16888KK105586 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7059 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9224} NA P{KK105586} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG16888 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60822 DroID - A comprehensive database of gene and protein interactions. • FBgn0032533 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34789
Orthologs
OrthoDB Orthologs (7) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6CC4MX Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6CC4MX)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG16888     Drosophila simulans   Dsim\GD22043 Y   Drosophila sechellia   Dsec\GM15116 Y   Drosophila erecta   Dere\GG10183 Y   Drosophila yakuba   Dyak\GE11438 Y   Drosophila ananassae   Dana\GF19723 Y   Drosophila willistoni   Dwil\GK19352 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (6) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22043 Drosophila sechellia Dsec\GM15116 Drosophila erecta Dere\GG10183 Drosophila yakuba Dyak\GE11438 Drosophila ananassae Dana\GF19723 Drosophila willistoni Dwil\GK19352
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v101267 P{KK105586}VIE-260B v32762 w1118; P{GD9224}v32762/TM3
Genomic Clones ( 2 )
	BACR16P12 BACR30I21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 6 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP07058
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	79435 bs78h01 EK209520 FGH129C02 IP06956
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032533 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34789
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135834 RefSeq (Proteins) • NP_609678 DDBJ / EMBL / GenBank • AAF53335 Entrez Gene - A searchable database of RefSeq genes. • 34789 UniProtKB/TrEMBL • Q9VJW0
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 60822 DroID - A comprehensive database of gene and protein interactions. • FBgn0032533 DRSC - Results from RNAi screens. • FBgn0032533 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032533 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16888-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032533 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34789 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34789 modMine - Data generated by the modENCODE project. • FBgn0032533
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG16888 (Bartkuhn et al., 2009, Keleman et al., 2009.8.5, Schirling et al., 2010, Shim et al., 2009)
Name Synonym
Secondary FlyBase IDs
References ( 12 )
Research paper	Schirling et al., 2010, Chromosoma 119(1): 99--113 Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60. [FBrf0209798] Bartkuhn et al., 2009, EMBO J. 28(7): 877--888 Active promoters and insulators are marked by the centrosomal protein 190. [FBrf0207850] Shim et al., 2009, J. Biol. Chem. 284(47): 32881--32894 Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. [FBrf0209321] Page et al., 2005, EMBO J. 24(24): 4304--4315 Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. [FBrf0190363]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]