FlyBase Gene Report: Dmel\Trpγ

General Information

Symbol

Dmel\Trpγ

Species

D. melanogaster

Name

Transient receptor potential cation channel γ

Annotation Symbol

CG5996

Feature Type

protein_coding_gene

FlyBase ID

FBgn0032593

Gene Model Status

Current

Stock Availability

11 publicly available

Gene Summary

A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction (By similarity). Forms a regulated cation channel when heteromultimerized with trpl. (UniProt, Q9VJJ7)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

trp-γ

Key Links

Genomic Location

Cytogenetic map

36A9-36A10

Sequence location

2L:16,663,454..16,676,701 [-]

Recombination map

2-52

RefSeq locus

NT_033779 REGION:16663454..16676701

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (20 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

enables cation channel activity

inferred from direct assay

(Jors et al., 2006, Xu et al., 2000)

enables mechanosensitive ion channel activity

inferred from direct assay

(Akitake et al., 2015)

enables protein binding

inferred from physical interaction with UniProtKB:P19334

(assigned by UniProt )

(Xu et al., 2000)

inferred from physical interaction with UniProtKB:P48994

(assigned by UniProt )

(Xu et al., 2000)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables calcium channel activity

inferred from sequence or structural similarity with UniProtKB:P19334

(assigned by UniProt )

(Xu et al., 2000)

enables inositol 1,4,5 trisphosphate binding

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

enables store-operated calcium channel activity

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (9 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in adult walking behavior

inferred from mutant phenotype

(Akitake et al., 2015)

involved_in cation transport

inferred from direct assay

(Xu et al., 2000)

involved_in neuromuscular process controlling posture

inferred from mutant phenotype

(Akitake et al., 2015)

Terms Based on Predictions or Assertions (6 terms)

CV Term

Evidence

References

involved_in calcium ion transmembrane transport

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in calcium ion transport

inferred from sequence or structural similarity with UniProtKB:P19334

(assigned by UniProt )

(Xu et al., 2000)

involved_in detection of light stimulus involved in visual perception

inferred from sequence or structural similarity with UniProtKB:P19334

(assigned by UniProt )

(Xu et al., 2000)

involved_in manganese ion transport

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of cytosolic calcium ion concentration

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in response to light stimulus

traceable author statement

(Voets and Nilius, 2003)

inferred from sequence or structural similarity with UniProtKB:P19334

(assigned by UniProt )

(Xu et al., 2000)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

part_of cation channel complex

inferred from physical interaction with FLYBASE:trpl; FB:FBgn0005614

(Xu et al., 2000)

located_in neuronal cell body

inferred from direct assay

(Akitake et al., 2015)

located_in proximal dendrite

inferred from direct assay

(Akitake et al., 2015)

located_in rhabdomere

inferred from direct assay

(assigned by UniProt )

(Xu et al., 2000)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

part_of cation channel complex

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

is_active_in integral component of plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000012230

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

TRANSIENT RECEPTOR POTENTIAL CHANNELS

Protein Family (UniProt)

Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. (Q9VJJ7)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

TRANSIENT RECEPTOR POTENTIAL CHANNELS -: The Transient Receptor Potential (TRP) channel family are cation channels conserved from invertebrates to humans. TRP channels respond to diverse stimuli and are involved in a number of environmental sensory pathways. (Adapted from FBrf0220930 and FBrf0225477).

Protein Function (UniProtKB)

(UniProt, Q9VJJ7)

Summary (Interactive Fly)

Ca channel protein activated by polyunsaturated fatty acids generated in a phospholipase C- and phospholipase A-dependent manner - motor coordination - olfactory sensitivity - Malpighian tubule fluid transport - photoresponse

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Trpγ for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure New Section

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VJJ7)

If you don't see the viewer to the right, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Unconventional translation start (CUG) postulated; FBrf0218597 (FlyBase analysis); additional N-terminal aa sequence conserved in Drosophila species.

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene

gene_with_start_codon_CUG

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Trpγ-RA

FBtr0080945

NM_135958

4232

1128

Trpγ-RB

FBtr0080946

NM_165169

4189

1128

Trpγ-RD

FBtr0335144

NM_001144358

5274

1188

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Trpγ-PA

FBpp0080498

127.1

1128

8.01

NP_609802

AAF53548

Trpγ-PB

FBpp0080499

127.1

1128

8.01

NP_723983

AAN10950

Trpγ-PD

FBpp0307143

133.5

1188

8.57

NP_001137830

ACL83036

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1128 aa isoforms: Trpγ-PA, Trpγ-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Interacts preferentially with trpl and interacts to a lower extent with trp.

(UniProt, Q9VJJ7)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Trpγ using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Trpgamma_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

scolopidial dendrite | subset of femoral chordotonal organ

(Akitake et al., 2015)

chordotonal neuron | subset of femoral chordotonal organ

• cell body

(Akitake et al., 2015)

scolopale cell | subset of femoral chordotonal organ

(Akitake et al., 2015)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

Trpγ-protein is expressed in scolopidial neurons where it labels cell bodies and proximal dendrites including the scolopidial cilium. Labeling is also detected in scolopale cells.

(Akitake et al., 2015)

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of cation channel complex

inferred from physical interaction with FLYBASE:trpl; FB:FBgn0005614

(Xu et al., 2000)

located_in neuronal cell body

inferred from direct assay

(Akitake et al., 2015)

located_in proximal dendrite

inferred from direct assay

(Akitake et al., 2015)

located_in rhabdomere

inferred from direct assay

(assigned by UniProt )

(Xu et al., 2000)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Trpγ in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Trpγ

View exonic expression by tissue for Dmel\Trpγ

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34991/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0032593

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0032593

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0032593

Flygut - An atlas of the Drosophila adult midgut

FBgn0032593

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Trpγ

Transgenic constructs containing regulatory region of Trpγ

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2L)Exel7066

(Ryder, 2004.4.26)

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Dcr-2^UAS.cDa, Scer\GAL4^e22c, Scer\GAL4^sqh.PW

Trpγ^KK107656

partially lethal, with Scer\GAL4^tin.CΔ4

Trpγ^GD539

partially lethal - majority die, with Scer\GAL4^pnr-MD237

Trpγ^GD539

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^e22c, Scer\GAL4^sqh.PW

Trpγ^GD539

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Trpγ^GD539

viable, with Scer\GAL4^Mef2.PR

Trpγ^GD539

Sterility

Allele

fertile

Other Phenotypes

Allele

abnormal locomotor behavior | adult stage

abnormal neurophysiology | recessive, with Scer\GAL4^Gr63a.PF

Trpγ^GD539

abnormal smell perception, with Scer\GAL4^Gr63a.PF

Trpγ^GD539

short lived, with Scer\GAL4^Ugt36A1.PK

some die during pupal stage, with Scer\GAL4^pnr-MD237

Trpγ^GD539

uncoordinated | adult stage

uncoordinated | adult stage, with Scer\GAL4^elav.PU

Trpγ^KK107656

uncoordinated | adult stage, with Scer\GAL4^iav.PU

Trpγ^KK107656

uncoordinated | adult stage, with Scer\GAL4^nan.PK

Trpγ^KK107656

uncoordinated | adult stage, with Scer\GAL4^nompA.cK

Trpγ^KK107656

uncoordinated | adult stage, with Scer\GAL4^Trpγ-G4, Trpγ^G4

Trpγ^KK107656

uncoordinated | adult stage, with Scer\GAL4^Trpγ-G4, Trpγ^KK107656

Trpγ^G4

uncoordinated | adult stage (with Df(2L)ED1109)

Trpγ^G4

uncoordinated | adult stage (with Trpγ¹)

Trpγ^G4

uncoordinated | adult stage (with Trpγ^G4)

Trpγ¹

Phenotype manifest in

Allele

adult pericardial cell, with Scer\GAL4^Ugt36A1.PK

scolopale cell

Trpγ¹

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (6)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\TRPC4

14 of 15

Yes

Hsap\TRPC5

12 of 15

Yes

Hsap\TRPC1

7 of 15

Yes

Hsap\TRPC3

4 of 15

Yes

Hsap\TRPC6

4 of 15

Yes

Hsap\TRPC7

4 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (7)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Trpc4

13 of 15

Yes

Mmus\Trpc5

12 of 15

Yes

Mmus\Trpc1

7 of 15

Yes

Mmus\Trpc3

4 of 15

Yes

Mmus\Trpc6

4 of 15

Yes

Mmus\Trpc7

4 of 15

Mmus\Trpc2

3 of 15

Yes

Rattus norvegicus (Norway rat) (8)

Rnor\Trpc4

12 of 13

Yes

Rnor\Trpc5

10 of 13

Yes

Rnor\Trpc1

5 of 13

Yes

Rnor\Trpc3

4 of 13

Yes

Rnor\Trpc6

4 of 13

Yes

Rnor\Trpc7

4 of 13

Yes

Rnor\LOC100909709

2 of 13

Yes

Rnor\Trpc2

1 of 13

Yes

Xenopus tropicalis (Western clawed frog) (7)

Xtro\trpc4

8 of 12

Yes

Xtro\trpc5

7 of 12

Yes

Xtro\trpc1

5 of 12

Yes

Xtro\trpc2

3 of 12

Yes

Xtro\trpc3

3 of 12

Yes

Xtro\trpc6

3 of 12

Yes

Xtro\LOC100492885

1 of 12

Danio rerio (Zebrafish) (16)

Drer\trpc4a

12 of 15

Yes

Drer\trpc5a

11 of 15

Yes

Drer\trpc4b

7 of 15

Yes

Drer\trpc1

6 of 15

Yes

Drer\trpc2a

4 of 15

Yes

Drer\trpc2b

3 of 15

Yes

Drer\trpc3

3 of 15

Yes

Drer\trpc5b

3 of 15

Yes

Drer\trpc6a

3 of 15

Yes

Drer\trpc7a

3 of 15

Yes

Drer\LOC103910003

2 of 15

Yes

Drer\trpc6b

2 of 15

Yes

Drer\LOC110438481

1 of 15

Yes

Drer\trpc7b

1 of 15

Yes

Drer\trpn1

1 of 15

Drer\zgc:110224

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (4)

Cele\trp-2

14 of 15

Yes

Cele\spe-41

3 of 15

Yes

Cele\trp-1

3 of 15

Cele\trp-4

1 of 15

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\YVC1

3 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Other Organism Orthologs (via OrthoDB)

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (3)

Gene Symbol

Score

Source

Alignment

7 of 10

trp

7 of 10

nompC

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

TRPC6; transient receptor potential cation channel subfamily C member 6

model of focal segmental glomerulosclerosis 2

IEA

(FlyBase, 2019-)

TRPC3; transient receptor potential cation channel subfamily C member 3

model of cerebellar ataxia type 41

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TRPC4; transient receptor potential cation channel subfamily C member 4

14 of 15

603651

TRPC5; transient receptor potential cation channel subfamily C member 5

12 of 15

300334

TRPC1; transient receptor potential cation channel subfamily C member 1

7 of 15

602343

TRPC3; transient receptor potential cation channel subfamily C member 3

4 of 15

602345

SPINOCEREBELLAR ATAXIA 41; SCA41

cerebellar ataxia type 41

TRPC6; transient receptor potential cation channel subfamily C member 6

4 of 15

603652

FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2

focal segmental glomerulosclerosis 2

TRPC7; transient receptor potential cation channel subfamily C member 7

4 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Trpγ

suppressible

Calx

(Akitake et al., 2015)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Calx

suppressible

Trpγ

(Akitake et al., 2015)

External Data

Subunit Structure (UniProtKB)

Interacts preferentially with trpl and interacts to a lower extent with trp.

(UniProt, Q9VJJ7 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0032593

MIST (protein-protein) - An integrated Molecular Interaction Database

Trpgamma

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0032593

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Phototransduction - fly

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-52

Cytogenetic map

36A9-36A10

Sequence location

2L:16,663,454..16,676,701 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

36A9-36A10

Limits computationally determined from genome sequence between P{PZ}dac^P and P{EP}grp^EP921&P{lacW}l(2)k13905^k13905

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-52

(FlyBase, 2016)

2-50.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

64311

w¹¹¹⁸; TI{TI}Trpγ¹

64313

w¹¹¹⁸; TI{GAL4}Trpγ^G4

25629

w¹¹¹⁸; Mi{ET1}Trpγ^MB06664

31298

y¹ v¹; P{TRiP.JF01243}attP2

31299

y¹ v¹; P{TRiP.JF01244}attP2

64344

y¹ w¹¹¹⁸; PBac{CH322-162M11}VK00033

64312

w¹¹¹⁸; P{UAS-Trpγ.A}2/CyO; TM2/TM6B, Tb¹

92696

y¹ w^*; TI{T-GEM.2}Trpγ^{CR70048-TG4.2}/SM6a

53313

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03542}attP2

VDRC

v105280

P{KK107656}VIE-260B

v9338

w¹¹¹⁸; P{GD539}v9338

Genomic Clones (24)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (3)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0032593

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0032593

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34991

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Akitake et al., 2015)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: trpγ CG5996

(FlyBase, 1996-)

Source for identity of: Trpγ trpγ

(FlyBase, 2009-)

Source for database merge of

Additional comments

Source for identity of trpγ CG5996 was sequence comparison ( date:000721 ).

(FlyBase, 1996-)

Other Comments

Trpγ is required for fine motor control.

(Akitake et al., 2015)

trpγ forms a receptor-activated outwardly rectifying cation channel which is activated by various polyunsaturated fatty acids generated in a phospholipase C- and phospholipase A₂-dependent manner.

(Jors et al., 2006)

trpγ forms a regulated cation channel with trpl.

(Xu et al., 2000)

trpγ-trpl heteromultimers contribute to the photoresponse.

(Xu et al., 2000)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 50 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34991

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VJJ7

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VJJ7

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

B7YZW4

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VJJ7

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0032593

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34991/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0032593

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Trpgamma_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0032593

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0032593

Flygut - An atlas of the Drosophila adult midgut

FBgn0032593

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0032593

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34991

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG5996

MARRVEL_MODEL - MARRVEL (model organism gene)

34991

modMine - A data warehouse for the modENCODE project

FBgn0032593

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VJJ7

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0032593

DRSC - Results frm RNAi screens

FBgn0032593

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0032593

FlyMine - An integrated database for Drosophila genomics

FBgn0032593

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Phototransduction - fly

MIST (protein-protein) - An integrated Molecular Interaction Database

Trpgamma

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

CG5996

(Chatterjee et al., 2014, Kanamori et al., 2013, Tsubouchi et al., 2012, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Ni et al., 2009, Ni et al., 2008, Hollien and Weissman, 2006)

DmTRPgamma

(Matsuura et al., 2009)

TRPgamma

(Riehle et al., 2018, Ni et al., 2009, Delmas et al., 2004)

TRPγ

(Montell, 2021, Su et al., 2018, Venkatachalam et al., 2014, Fowler and Montell, 2013, Jors et al., 2006, Montell, 2005, Zelhof et al., 2003, Xu et al., 2000, Montell, 1999)

Trp-gamma

(Zhang et al., 2013)

Trpgamma

(Yan et al., 2018, Fu et al., 2017, Menuz et al., 2014, Shieh and Bonini, 2011)

Trpγ

(Hehlert et al., 2021, Moon et al., 2021, Fujisawa et al., 2020, Aggarwal et al., 2019)

dTRPg

(Voets and Nilius, 2003)

dTRPγ

(Wicher et al., 2006)

trp-gamma

(Roos et al., 2005)

trp-γ

(Hardie, 2001, Hardie and Raghu, 2001)

trpgamma

(Wasbrough et al., 2010, Hollien and Weissman, 2006)

trpγ

(Jacobs and Sehgal, 2020, Ma and Freeman, 2020, Rimal and Lee, 2019, Zhang et al., 2016, Akitake et al., 2015, Wong et al., 2014, Kanamori et al., 2013, Zhang et al., 2013, Tsubouchi et al., 2012, Kain et al., 2010, Kim et al., 2010, Kwon et al., 2010, Kwon et al., 2010, Kwon et al., 2008, Montell, 2005, Nelson et al., 2005)

Name Synonyms

Transient receptor potential cation channel γ

Trpgamma

(Guo et al., 2020)

Trpγ

(Nakayama et al., 2014)

trpgamma

(Georlette et al., 2007)

trpγ

(Kwon et al., 2008)

Secondary FlyBase IDs

Datasets (1)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (1)

Result

Result Type

Title

scRNAseq_2020_Cho_NI96HL_seq_clustering

cell clustering analysis

Clustering analysis of circulating hemocytes from non-infested larvae at 96 h after egg-laying

References (77)

The following external sites may use different assemblies or annotations than FlyBase.

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