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Gene Dmel\CG17912

General Information
Symbol	Dmel\CG17912	Species	D. melanogaster
Name		Annotation symbol	CG17912
Feature type	protein_coding_gene	FlyBase ID	FBgn0032600
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	36A14-36A14	Sequence location	2L:16,743,404..16,753,706 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG17912 (FBgn0032600). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Zinc finger, BED-type predicted; Zinc finger, C2H2; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1636978_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG17912. Gene sequence location is 2L:16743404..16753706.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN29387 HFA02642 HFA02643
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 36A14-36A14   Limits computationally determined from genome sequence between P{lacW}gluk08819 and P{lacW}Mhck10423&P{lacW}Cask03902
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG17912 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG17912-RA FBtr0080893  NM_135964   1613   357 CG17912-RB FBtr0113041  NM_001103697   1997   562 CG17912-RC FBtr0308802     5647   562 CG17912-RD FBtr0308803     6094   562
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG17912-PA   FBpp0080450   38.4   357   9.81     NP_609808   AAF53563 CG17912-PB   FBpp0111954   59.3   562   10.27     NP_001097167   ABV53686 CG17912-PC   FBpp0300959   59.3   562   10.27       CG17912-PD   FBpp0300960   59.3   562   10.27
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, BED-type predicted (IPR003656) Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263178   AA264538   AA392611   AA440493   AA440494   AA440495   AA540105   AA802826   AA949059   AE014134 AAF53563   AE014134 ABV53686   AI063461   AI063501   AI387921   AI517166   AI520281   AQ024964   AW941824   AW942777   AY051534 AAK92958   AY094808 AAM11161   BG634947   BI163679   BI167999   BI229109   BI234761   BI243469   BI370261   BI374017   BI580043   BI638629   BP552816   BQ103638   BT099800   BT099823   BX024106   BX036055   CK657866   CO177726   CO185866   CO188203   CO189862   CO264876   CO265731   CO267196   CO268455   CO272590   CO275840   CO276781   CO278459   CO281429   CO287627   CO287763   CO289531   CO289661   CO289662   CO290982   CO294081   CO294630   CO296901   CO299534   CO299668   CO300346   CO300518   CO302188   CO303821   CO304775   CO305350   CO305923   CO306388   CO306993   CO309052   CO312904   CO313150   CO313906   CO319519   CO320760   CO321514   CO324426   CO332512   CO339481   CO344735   CZ466989   CZ466990   CZ490478   DN154441   EC058801   EC060181   EC065742   EC065922   EC067484   EC067826   EC069610   EC070054   EC072431   EC073717   EC076241   EC076608   EC077461   EC086864   EC088364   EC089429   EC090545   EC091006   EC195464   EC196128   EC197377   EC197469   EC197931   EC202521   EC204769   EC205136   EC206984   EC207732   EC210335   EC214054   EC214186   EC223259   EC225579   EC226240   EC226358   EC228627   EC228629   EC230690   EC233195   EC235255   EC235864   EC236268   EC239629   EC240598   EC242350   EC243750   EC245292   EC245569   EC245814   EC246316   EC248510   EC250248   EL874073   EL885528   EV585308   GH944390   GH958609   GH967158   GH969138   GH970040   GH977072   GH983633   GH984924
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SX73 Q9VJI6 A8DZ09
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032600    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032600 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032600 expression level Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2244) embryo 02-04hr  (4565) embryo 04-06hr  (4344) embryo 06-08hr  (4520) embryo 08-10hr  (3425) embryo 10-12hr  (3110) embryo 12-14hr  (2634) embryo 14-16hr  (2360) embryo 16-18hr  (1717) embryo 18-20hr  (1318) embryo 20-22hr  (1688) embryo 22-24hr  (1333) larva L1  (1319) larva L2  (980) larva L3 12hr old  (870) larva L3 puffstage 1-2  (695) larva L3 puffstage 3-6  (1388) larva L3 puffstage 7-9  (1360) white prepupae new  (1583) white prepupae 12hr  (1436) white prepupae 24hr  (2084) pupae 2d postWPP  (1266) pupae 3d postWPP  (813) pupae 4d postWPP  (563) adult male 01day  (811) adult male 05day  (1058) adult male 30day  (901) adult female 01day  (1142) adult female 05day  (1394) adult female 30day  (1507) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2244) embryo 02-04hr  (4565) embryo 04-06hr  (4344) embryo 06-08hr  (4520) embryo 08-10hr  (3425) embryo 10-12hr  (3110) embryo 12-14hr  (2634) embryo 14-16hr  (2360) embryo 16-18hr  (1717) embryo 18-20hr    1318 embryo 20-22hr  (1688) embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new  (1583) white prepupae 12hr  1436 white prepupae 24hr  (2084) pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day  1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032600 expression level Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2244) embryo 02-04hr  (4565) embryo 04-06hr  (4344) embryo 06-08hr  (4520) embryo 08-10hr  (3425) embryo 10-12hr  (3110) embryo 12-14hr  (2634) embryo 14-16hr  (2360) embryo 16-18hr  (1717) embryo 18-20hr  (1318) embryo 20-22hr  (1688) embryo 22-24hr  (1333) larva L1  (1319) larva L2  (980) larva L3 12hr old  (870) larva L3 puffstage 1-2  (695) larva L3 puffstage 3-6  (1388) larva L3 puffstage 7-9  (1360) white prepupae new  (1583) white prepupae 12hr  (1436) white prepupae 24hr  (2084) pupae 2d postWPP  (1266) pupae 3d postWPP  (813) pupae 4d postWPP  (563) adult male 01day  (811) adult male 05day  (1058) adult male 30day  (901) adult female 01day  (1142) adult female 05day  (1394) adult female 30day  (1507) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  2244 embryo 02-04hr  (4565) embryo 04-06hr  (4344) embryo 06-08hr  (4520) embryo 08-10hr  (3425) embryo 10-12hr  (3110) embryo 12-14hr  (2634) embryo 14-16hr  2360 embryo 16-18hr  1717 embryo 18-20hr    1318 embryo 20-22hr  1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new  1583 white prepupae 12hr  1436 white prepupae 24hr  2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day  1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2244 embryo 02-04hr    4565 embryo 04-06hr    4344 embryo 06-08hr    4520 embryo 08-10hr    3425 embryo 10-12hr    3110 embryo 12-14hr    2634 embryo 14-16hr    2360 embryo 16-18hr    1717 embryo 18-20hr    1318 embryo 20-22hr    1688 embryo 22-24hr    1333 larva L1    1319 larva L2    980 larva L3 12hr old    870 larva L3 puffstage 1-2    695 larva L3 puffstage 3-6    1388 larva L3 puffstage 7-9    1360 white prepupae new    1583 white prepupae 12hr    1436 white prepupae 24hr    2084 pupae 2d postWPP    1266 pupae 3d postWPP    813 pupae 4d postWPP    563 adult male 01day    811 adult male 05day    1058 adult male 30day    901 adult female 01day    1142 adult female 05day    1394 adult female 30day    1507 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032600    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032600 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032600 expression level Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032600 expression level Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    289.675 Larval Midgut    76.7 Larval Hindgut    128.7 Larval Malpighian Tubules    192.3 Larval Fat Body    125.3 Larval Salivary Gland    175.2 Larval Trachea    179.975 Larval Carcass    118.175 Adult Head    76.3 Adult Eye    137.575 Adult Brain    142 Adult Thoracic-Abdominal Ganglion    124.6 Adult Crop    134.2 Adult Midgut    76.3 Adult Hindgut    102.3 Adult Malpighian Tubules    92.4 Adult Fat Body    109.7 Adult Salivary Gland    123.4 Adult Heart    125.225 Adult VirginFemale Spermatheca    132.2 Adult InseminatedFemale Spermatheca    153.6 Adult Ovary    249.5 Adult Testis    42.2 Adult Male Accessory Gland    100.4 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    76.3   NA  Eye    137.575   NA  Brain    142   289.675  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    124.6   NA  Crop    134.2   76.7  Midgut    76.3   128.7  Hindgut    102.3   192.3  Malpighian Tubules    92.4   125.3  Fat Body    109.7   175.2  Salivary Gland    123.4   NA  Heart    125.225   179.975  Trachea    NA   NA  VirginFemale Spermatheca    132.2   NA  InseminatedFemale Spermatheca    153.6   NA  Ovary    249.5   NA  Testis    42.2   NA  Male Accessory Gland    100.4   118.175  Carcass    73.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032600 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17912-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG17912GD9485 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG17912 Class Mutagen Stocks Known lesion CG17912c01215 piggyBac transposase 1 -- CG17912EP819 P-element activity 1 -- CG17912f07740 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG17912 Class Mutagen Stocks Known lesion CG17912GD9485 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes CG17912JF02830 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG17912KK109387 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6039 (Ryder, 2004.4.26) Df(2L)Exel7067 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9485} NA P{KK109387} NA P{TRiP.JF02830} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG17912EP819 NA insertion of enhancer trap P{lacW}l(2)SH1473SH1473 No miscellaneous insertions PBac{PB}CG17912c01215 NA PBac{WH}CG17912f07740 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR003656 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
intracellular inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG17912 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61011 DroID - A comprehensive database of gene and protein interactions. • FBgn0032600 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35004
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15358 Dere\GG22767 Dgri\GH11562 Dmoj\GI17053 Dpse\GA14721 Dsec\GM17201 Dsim\GD24078 Dvir\GJ17303 Dwil\GK18230 Dyak\GE12761
Curated drosophilid orthologs	Dpse\GA14721
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL005736-PB Aedes aegypti (mosquito) AGAP010143-PA Anopheles gambiae (mosquito) XP_395716.3 Apis mellifera (honey bee) At1g30970.1 Arabidopsis thaliana (wall cress) 230444 Branchiostoma floridae (lancelet) BGIBMGA014135-PA Bombyx mori (silk worm) ENSBTAP00000011700 Bos taurus (bovine) CBP25466 Caenorhabditis briggsae (nematode) CE05159 Caenorhabditis elegans (worm) ENSCAFP00000027188 Canis familiaris (dog) JA01509 Caenorhabditis japonica (nematode) CPIJ000846 Culex pipens (mosquito) ENSCPOP00000001559 Cavia porcellus (guinea pig) ENSCSAVP00000009377 Ciona savignyi (sedentary tunicate) 162061 Capitella spl (polychaete worm) 198826 Daphnia pulex (daphnia) ENSDARP00000044858 Danio rerio (zebra fish) ENSECAP00000015268 Equus caballus (horse) ENSGACP00000025650 Gymnopilus aculeatus (mushroom) ENSGALP00000005461 Gallus gallus (chicken) ENSP00000378172 Homo sapiens (human) ISCW008407-PA Ixodes scapularis (deer tick) 38851 Monocosta brevicollis (choanoflagellate) ENSMODP00000023944 Monodelphis domestica (gray opossum) ENSMMUP00000022184 Macaca mulatta (rhesus monkey) ENSMUSP00000054168 Mus musculus (house mouse) XP_001607295.1 Nasonia vitripennis (wasp) ENSOANP00000017593 Ornithorynchus anatinus (platypus) ENSORLP00000004157 Oryzias latipes (japanese killifish) PHUM001197-PA Pediculus humanus (human body louse) 87880 Physcomitrella patens (moss) ENSPPYP00000009174 Pongo pygmaeus (orangutan) 796265 Populus trichocarpa (black cottonwood) ENSPTRP00000057273 Pan troglodytes (chimpanzee) PVX_094685 Plasmodium vivax (protozoal parasite) ENSRNOP00000000252 Rattus norvegicus (norway rat) Smp_025560 Schistosoma mansoni (trematode parasite) XP_800033.2 Strongylocentrotus purpuratus (purple sea urchin) 52848 Trichoplax adhaerens (metazoa) XP_970267.1 Tribolium castaneum (red flour beetle) 3712.m00079 Tetrahymena thermophila (ciliate protozoa) 94663.m00101 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000056068 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11880 NV11778 LH18896 FBgn0230483 FBgn0220229 FBgn0195434 FBgn0172112 JGI_V11_198826 FBgn0074748 FBgn0156383 FBgn0119042 FBgn0114932 FBgn0092383 CPIJ000846 BGIBMGA014135 ACYPI008654 ACYPI007171 GB16439 AGAP010143 AAEL005736 PHUM097800 GLEAN_06644
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	27996 y1 v1; P{TRiP.JF02830}attP2 17198 w1118; P{EP}CG17912EP819/CyO
Harvard	- PBac{PB}CG17912c01215 - PBac{WH}CG17912f07740
VDRC	v104498 P{KK109387}VIE-260B v40107 w1118 P{GD9485}v40107 v45449 w1118; P{GD9485}v45449 v45448 w1118; P{GD9485}v45448/CyO
Genomic Clones ( 1 )
	BACR26O03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 132 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH18623 LD27810
Other clones	MIP03431 MIP03731
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT31359 GH03288 GH03361 GH27816 GM06371 LD06475 LD07616 LD11849 LD13532 LD13542 LD13546 LD19470 LD40394 LP24492 RE03139 RE08529 RE26823 RE30517 RE41121 RE56722 RE61518 RE74164 SD20972
Other clones	671 8974 9358 17938 30836 34401 42329 47586 50558 53979 59288 60759 66054 75416 76249 81394 102129 105165 106189 106832 107804 109357 145716 147537 161746 173992 183160 192509 273252 273255 273860 276895 CK01.12D.E9 CK01.56B.E9 CK01.60B.D4 CK01.67B.A6 CK01.83A.A6 CK01.83D.D1 CK01.90D.E10 CK01.91C.F9 CK01.91C.G9 CK01.97D.F1 CK01.111D.H10 CK01.114B.A10 CK01.114B.F10 CK01.130D.E8 CK01.142B.F3 Dmel_dig_012565_0671_3151 EK013818 EK038406 EK045419 EK054135 EK066335 EK066713 EK071249 EK071721 EK071725 EK075721 EK091503 EK107734 EK118922 EK122036 EK130124 EK140559 EK143507 EK149051 EK157135 EK175737 EK176310 EK178007 EK178417 EK183344 EK185826 EK193638 EK205939 EK207327 EK215404 EK230529 EK231718 EK234259 EK242826 EK246163 EK248262 EK249812 EK250930 EK252960 EK260003 EK266437 EK278454 EK288016 EK303724 EP02110 EP19813 FGM221A01 IP14133 IP16907 RP004028846 RP004207829 RP004241859 RP004302850 RP004432940 RP004445491 RP004470806 RP004504914 UUGC1048
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032600 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35004
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG17912 BcDNA:LD27810 (FlyBase, 1996-)
Additional comments	Source for merge of CG17912 BcDNA:LD27810 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135964 NM_001103697 RefSeq (Proteins) • NP_609808 NP_001097167 DDBJ / EMBL / GenBank • AA949059 AAF53563 AAK92958 AAM11161 ABV53686 AI387921 AQ024964 AW941824 AW942777 AY051534 AY094808 CZ466989 CZ466990 CZ490478 Entrez Gene - A searchable database of RefSeq genes. • 35004 UniProtKB/TrEMBL • A8DZ09 Q8SX73 Q9VJI6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, BED-type predicted (IPR003656) Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61011 DroID - A comprehensive database of gene and protein interactions. • FBgn0032600 DRSC - Results from RNAi screens. • FBgn0032600 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032600 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17912-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032600 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35004 InParanoid A subset of ortholog calls from InParanoid. • AAEL005736-PB Aedes aegypti (mosquito) AGAP010143-PA Anopheles gambiae (mosquito) XP_395716.3 Apis mellifera (honey bee) At1g30970.1 Arabidopsis thaliana (wall cress) 230444 Branchiostoma floridae (lancelet) BGIBMGA014135-PA Bombyx mori (silk worm) ENSBTAP00000011700 Bos taurus (bovine) CBP25466 Caenorhabditis briggsae (nematode) CE05159 Caenorhabditis elegans (worm) ENSCAFP00000027188 Canis familiaris (dog) JA01509 Caenorhabditis japonica (nematode) CPIJ000846 Culex pipens (mosquito) ENSCPOP00000001559 Cavia porcellus (guinea pig) ENSCSAVP00000009377 Ciona savignyi (sedentary tunicate) 162061 Capitella spl (polychaete worm) 198826 Daphnia pulex (daphnia) ENSDARP00000044858 Danio rerio (zebra fish) ENSECAP00000015268 Equus caballus (horse) ENSGACP00000025650 Gymnopilus aculeatus (mushroom) ENSGALP00000005461 Gallus gallus (chicken) ENSP00000378172 Homo sapiens (human) ISCW008407-PA Ixodes scapularis (deer tick) 38851 Monocosta brevicollis (choanoflagellate) ENSMODP00000023944 Monodelphis domestica (gray opossum) ENSMMUP00000022184 Macaca mulatta (rhesus monkey) ENSMUSP00000054168 Mus musculus (house mouse) XP_001607295.1 Nasonia vitripennis (wasp) ENSOANP00000017593 Ornithorynchus anatinus (platypus) ENSORLP00000004157 Oryzias latipes (japanese killifish) PHUM001197-PA Pediculus humanus (human body louse) 87880 Physcomitrella patens (moss) ENSPPYP00000009174 Pongo pygmaeus (orangutan) 796265 Populus trichocarpa (black cottonwood) ENSPTRP00000057273 Pan troglodytes (chimpanzee) PVX_094685 Plasmodium vivax (protozoal parasite) ENSRNOP00000000252 Rattus norvegicus (norway rat) Smp_025560 Schistosoma mansoni (trematode parasite) XP_800033.2 Strongylocentrotus purpuratus (purple sea urchin) 52848 Trichoplax adhaerens (metazoa) XP_970267.1 Tribolium castaneum (red flour beetle) 3712.m00079 Tetrahymena thermophila (ciliate protozoa) 94663.m00101 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000056068 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35004 modMine - Data generated by the modENCODE project. • FBgn0032600 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11880 NV11778 LH18896 FBgn0230483 FBgn0220229 FBgn0195434 FBgn0172112 JGI_V11_198826 FBgn0074748 FBgn0156383 FBgn0119042 FBgn0114932 FBgn0092383 CPIJ000846 BGIBMGA014135 ACYPI008654 ACYPI007171 GB16439 AGAP010143 AAEL005736 PHUM097800 GLEAN_06644
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:LD27810   CG17912 (Keleman et al., 2009.8.5, Perkins et al., 2009, Pessa et al., 2010)
Name Synonym
Secondary FlyBase IDs
	FBgn0062458
References ( 19 )
Research paper	Pessa et al., 2010, PLoS ONE 5(10): e13215 Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways. [FBrf0212091] Schneider et al., 2004, Proc. Natl. Acad. Sci. USA 101(26): 9584--9589 Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. [FBrf0179434] Brody et al., 2002, Mech. Dev. 113(1): 41--59 Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Oh et al., 2003, Genetics 163(1): Table S1. [FBrf0157097]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Mount, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126690]