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Gene Dmel\Lrch

General Information
Symbol	Dmel\Lrch	Species	D. melanogaster
Name	Leucine-rich-repeats and calponin homology domain protein	Annotation symbol	CG6860
Feature type	protein_coding_gene	FlyBase ID	FBgn0032633
Gene Model Status	Current	Stock availability	13 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	36C7-36C7	Sequence location	2L:17,367,511..17,384,115 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Leucine-rich-repeats and calponin homology domain protein is referred to in FlyBase by the symbol Dmel\Lrch (CG6860, FBgn0032633). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process: Ras protein signal transduction. 17 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Calponin homology domain; Cyclic nucleotide-binding domain; Leucine rich repeat 4; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult midgut, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1627326_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG6860. Gene sequence location is 2L:17367511..17384115.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 36C7-36C7   Limits computationally determined from genome sequence between P{lacW}Mhck10423&P{lacW}Cask03902 and P{lacW}Aac11k06710
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Lrch for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Lrch-RA FBtr0080968  NM_165212   3449   809 Lrch-RB FBtr0080969  NM_135990   4427   1135 Lrch-RC FBtr0339797     5650   1079
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Lrch-PA   FBpp0080521   87.1   809   8.85     NP_724046   AAN10986 Lrch-PB   FBpp0080522   124.2   1135   6.82     NP_609834   AAF53603 Lrch-PC   FBpp0308842   118.8   1079   6.72
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Leucine rich repeat 4 (IPR025875) Cyclic nucleotide-binding domain (IPR000595) Leucine-rich repeat (IPR001611) Calponin homology domain (IPR001715) Leucine-rich repeat, typical subtype (IPR003591)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392637   AA698452   AA942379   AE014134 AAF53603   AE014134 AAN10986   AI534733   AW944524   AY052126 AAK93550   BE978171   BF486409   BF487757   BH614873   BI170639   BI640357   BP554309   BP554310   BP555283   CO184141   CO190183   CO195874   CO196190   CO268119   CO273091   CO273526   CO286019   CO286280   CO289850   CO294027   CO294193   CO296990   CO302171   CO305705   CO306268   CO311542   CO319397   CO325489   CO326878   CO331936   CO335658   CO339618   CO340804   CO344300   CZ467425   EC059557   EC064694   EC065852   EC070254   EC083337   EC085748   EC202295   EC205232   EC207439   EC212761   EC213191   EC214777   EC218273   EC218890   EC227120   EC232513   EC234525   EC236225   EC238897   EC241803   EC252107   EC256284   EC260607   EC265918   GH941294   GH941659   GH942653   GH943364   GH943798   GH944257   GH944417   GH944941   GH946004   GH946434   GH947449   GH947611   GH947869   GH948901   GH949060   GH950707   GH951550   GH952448   GH953666   GH954626   GH954972   GH955392   GH955970   GH956030   GH958406   GH959071   GH959546   GH962903   GH962911   GH963609   GH963874   GH964199   GH966451   GH966465   GH966952   GH967053   GH967281   GH967786   GH968145   GH968411   GH968463   GH969366   GH970731   GH973070   GH973914   GH974683   GH977381   GH977787   GH978103   GH978508   GH979308   GH980619   GH981306   GH981919   GH983770   GH984345
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q960C5 Q9VJE6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   central brain anlage in statu nascendi   (Fisher et al., 2012) dorsal ectoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi organism | faint & ubiquitous   (Fisher et al., 2012) ventral ectoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi antennal anlage in statu nascendi   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage in statu nascendi dorsal head epidermis anlage in statu nascendi   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage in statu nascendi visual anlage in statu nascendi   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage in statu nascendi embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 11 -- 12   central brain primordium   (Fisher et al., 2012) garland cell primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) tracheal primordium   (Fisher et al., 2012) ventral epidermis primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic central brain neuron   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval dorsal vessel   (Fisher et al., 2012) embryonic/larval lymph gland   (Fisher et al., 2012) embryonic/larval nervous system   (Fisher et al., 2012) embryonic/larval pericardial cell   (Fisher et al., 2012) gonad   (Fisher et al., 2012) lateral cord neuron   (Fisher et al., 2012) ventral midline   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cell cortex inferred from direct assay (Foussard et al., 2010) cleavage furrow inferred from direct assay (Foussard et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult midgut, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    350.7 Larval Midgut    91.1 Larval Hindgut    35.9 Larval Malpighian Tubules    19.2 Larval Fat Body    33.3 Larval Salivary Gland    41 Larval Trachea    52.525 Larval Carcass    53.575 Adult Head    62.1 Adult Eye    84.45 Adult Brain    166.3 Adult Thoracic-Abdominal Ganglion    159.4 Adult Crop    59.9 Adult Midgut    145.2 Adult Hindgut    27.3 Adult Malpighian Tubules    30.9 Adult Fat Body    31.5 Adult Salivary Gland    27.8 Adult Heart    41.675 Adult VirginFemale Spermatheca    25.3 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    192 Adult Testis    56 Adult Male Accessory Gland    32.6 Adult Carcass    26.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    62.1   NA  Eye    84.45   NA  Brain    166.3   350.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    159.4   NA  Crop    59.9   91.1  Midgut    145.2   35.9  Hindgut    27.3   19.2  Malpighian Tubules    30.9   33.3  Fat Body    31.5   41  Salivary Gland    no informative data   NA  Heart    41.675   52.525  Trachea    NA   NA  VirginFemale Spermatheca    25.3   NA  InseminatedFemale Spermatheca    18.8   NA  Ovary    192   NA  Testis    56   NA  Male Accessory Gland    32.6   53.575  Carcass    26.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    24 central nervous system, pupae P8    19 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    2 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    3 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    13 ovary, mated 4-day female    12 testis, mated 4-day male    5 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr  (29) embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr  29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    13 embryo 04-06hr    29 embryo 06-08hr    23 embryo 08-10hr    20 embryo 10-12hr    17 embryo 12-14hr    19 embryo 14-16hr    16 embryo 16-18hr    15 embryo 18-20hr    8 embryo 20-22hr    5 embryo 22-24hr    7 larva L1    6 larva L2    3 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    9 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    11 pupae 3d postWPP    8 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1  (28) embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3  (28) eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC  (30) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1  28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3  28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC  30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    24 Schneider line 2 Sg4    6 embryonic 1182-4H    12 embryonic GM2    11 embryonic Kc167    11 embryonic S1    28 embryonic S3    9 leg disc CME L1    5 wing disc CME-W2    5 wing disc ML-DmD8    8 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    25 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    10 ovary fGS/OSS    12 ovary OSC    30 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    13 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	BDGP expression data • SD07737 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032633 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6860-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Lrch Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable LrchT1-36C viable, with Scer\GAL4pnr-MD237 LrchGD1753 Phenotype manifest in Allele
Classical Alleles ( 12 )
For All Classical Alleles Show
Allele of Lrch Class Mutagen Stocks Known lesion Lrchc01766 piggyBac transposase 1 -- LrchCB-6159-3 1 -- LrchCB-6639-3 1 -- Lrchd04045 1 -- LrchKG02383 P-element activity 1 -- LrchMI05027 1 -- LrchNP0317 1 -- LrchNP0645 1 -- LrchUM-8081-3 1 -- LrchDf FLPase 0 Yes LrchGX8630 Delta2-3 0 -- LrchT1-36C P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Lrch Class Mutagen Stocks Known lesion LrchGD1753 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes LrchGL01255 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes LrchHM05264 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes LrchKK102050 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes LrchNIG.6860R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel8036 (Ryder, 2004.4.26)
Partially disrupted in	Df(2L)LrchDf (Foussard et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.6860R} NA P{TRiP.GL01255} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}LrchMI05027 NA P{RS3}LrchCB-6159-3 NA P{RS3}LrchCB-6639-3 NA P{RS3}LrchUM-8081-3 NA P{SUPor-P}LrchKG02383 NA P{T1}LrchT1-36C NA PBac{PB}Lrchc01766 NA insertion of enhancer trap binary system P{GawB}LrchNP0317 No P{GawB}LrchNP0645 No insertion of mobile activating element P{EP}LrchGX8630 NA P{XP}Lrchd04045 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
cell cortex inferred from direct assay (Foussard et al., 2010) cleavage furrow inferred from direct assay (Foussard et al., 2010)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
Ras protein signal transduction inferred from sequence or structural similarity with EMBL:AF068919 (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Lrch allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61037 DroID - A comprehensive database of gene and protein interactions. • FBgn0032633 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35041
Orthologs
OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6CG0TP Dipteran inclusive ortholog search EOG6V43GS Insect inclusive ortholog search EOG6M90MR Arthropod inclusive ortholog search EOG6QNKBD Metazoa inclusive ortholog search EOG6RRK9J
Orthologs in Drosophila Species (EOG6CG0TP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Lrch     Drosophila simulans   Dsim\GD21875 Y   Drosophila sechellia   Dsec\GM17134 Y   Drosophila erecta   Dere\GG21751 Y   Drosophila yakuba   Dyak\GE13141 Y   Drosophila ananassae   Dana\GF15108 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19911 Y   Drosophila persimilis   Dper\GL18758 Y   Drosophila willistoni   Dwil\GK23871 Y   Drosophila virilis   Dvir\GJ16236 Y   Drosophila mojavensis   Dmoj\GI14262 Y   Drosophila grimshawi   Dgri\GH10082 Y
Orthologs in non-Drosophila Dipterans (EOG6V43GS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012619   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014003   Anopheles gambiae Malaria mosquito  Agam\AGAP010012   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013227
Orthologs in non-Dipteran Insects (EOG6M90MR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB42224   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002098   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH27248   Atta cephalotes Leafcutter ant  Acep\ACEP26485   Camponotus floridanus Florida carpenter ant  Cflo\CFLO12633   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22256   Linepithema humile Argentine ant  Lhum\LH19880   Pogonomyrmex barbatus Red harvester ant  Pbar\PB19864   Solenopsis invicta Red fire ant  Sinv\SINV23296   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009321   Bombyx mori Silkmoth  Bmor\BGIBMGA014353   Bombyx mori Silkmoth  Bmor\BGIBMGA014544   Pediculus humanus Human body louse  Phum\PHUM584220   Tribolium castaneum Red flour beetle  Tcas\TC013766
Orthologs in non-Insect Arthropods (EOG6QNKBD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_33839   Daphnia pulex Water flea  Dpux\acpP   Daphnia pulex Water flea  Dpux\nop5   Daphnia pulex Water flea  Dpux\JGI_V11_218254   Ixodes scapularis Deer tick  Isca\ISCW017818
Orthologs in non-Arthropod Metazoa (EOG6RRK9J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\C14F11.2
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD21875 Drosophila sechellia Dsec\GM17134 Drosophila erecta Dere\GG21751 Drosophila yakuba Dyak\GE13141 Drosophila ananassae Dana\GF15108 Drosophila pseudoobscura pseudoobscura Dpse\GA19911 Drosophila persimilis Dper\GL18758 Drosophila willistoni Dwil\GK23871 Drosophila virilis Dvir\GJ16236 Drosophila mojavensis Dmoj\GI14262 Drosophila grimshawi Dgri\GH10082
Stocks & Reagents
Stocks Listed in FlyBase ( 13 )
Bloomington	38084 y1 w*; Mi{MIC}LrchMI05027 31871 y1 sc* v1; P{TRiP.HM05264}attP2 13215 y1 w67c23; P{SUPor-P}LrchKG02383
Harvard	- P{XP}Lrchd04045 - PBac{PB}Lrchc01766
Kyoto	123953 w1118; P{RS3}LrchCB-6159-3 124154 w1118; P{RS3}LrchCB-6639-3 124327 w1118; P{RS3}LrchUM-8081-3 103691 w*; P{GawB}LrchNP0645 / CyO 112132 y* w*; P{GawB}LrchNP0317
VDRC	v107047 P{KK102050}VIE-260B v7306 w1118; P{GD1753}v7306/TM3
	More stocks available...
Genomic Clones ( 1 )
	BACR21E16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 116 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD07737
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT20708 AT22801 HL04709 LD12870 LD26544 RE12162 SD23186
Other clones	9771 11322 55680 59258 76348 80795 82328 99456 102358 144544 146663 165770 173619 214343.29 214503.26 214503.27 274700 542596 bs75a01 CK01.58B.E5 CK01.79A.H8 CK01.80C.C2 CK01.82B.G4 CK01.91B.H9 CK01.119A.D9 EC27219 EC42519 EK001809 EK046919 EK061464 EK062341 EK072231 EK090215 EK109458 EK111327 EK183316 EK196636 EK205528 EK206304 EK215624 EK225231 EK249260 EK250652 EK278006 EK302044 EN10929 EP02409 EP04906 EP11363 EP19023 FGM229B08 FGM234D10 RP004014382 RP004034450 RP004086040 RP004088273 RP004098796 RP004105248 RP004111697 RP004125763 RP004144117 RP004160599 RP004169190 RP004190072 RP004192471 RP004199806 RP004204891 RP004205606 RP004207481 RP004209485 RP004219936 RP004225158 RP004227913 RP004232702 RP004236679 RP004239929 RP004241589 RP004243113 RP004247225 RP004251739 RP004252588 RP004258100 RP004263035 RP004263941 RP004265209 RP004268124 RP004278364 RP004292904 RP004357903 RP004373328 RP004387863 RP004422294 RP004442737 RP004454586 RP004455123 RP004459084 RP004462804 RP004469373 RP004472827 RP004474124 RP004478886 RP004479353 RP004506997 RP004510126 RP004512642 RP004519805 RP004519878 RP004556429
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032633 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35041
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Lrch CG6860 (Foussard et al., 2010)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135990 NM_165212 RefSeq (Proteins) • NP_609834 NP_724046 DDBJ / EMBL / GenBank • AAF53603 AAK93550 AAN10986 AI534733 AW944524 AY052126 BH614873 CZ467425 Entrez Gene - A searchable database of RefSeq genes. • 35041 UniProtKB/TrEMBL • Q9VJE6 Q960C5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Leucine rich repeat 4 (IPR025875) Cyclic nucleotide-binding domain (IPR000595) Leucine-rich repeat (IPR001611) Calponin homology domain (IPR001715) Leucine-rich repeat, typical subtype (IPR003591) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • SD07737
Linkouts
	BioGRID - A database of protein and genetic interactions • 61037 DroID - A comprehensive database of gene and protein interactions. • FBgn0032633 DRSC - Results from RNAi screens. • FBgn0032633 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032633 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6860-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032633 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35041 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35041 modMine - Data generated by the modENCODE project. • FBgn0032633
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG6860 (Perkins et al., 2009, Foussard et al., 2010, Wasbrough et al., 2010, Slack et al., 2010, Haynes et al., 2006, Keleman et al., 2009.8.5, Kim et al., 2005, Azad et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1) CT21229 (Hynes and Zhao, 2000) dLRCH (Foussard et al., 2010) Lrch (Paik et al., 2012)
Name Synonym	Leucine-rich-repeats and calponin homology domain protein
Secondary FlyBase IDs
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Azad et al., 2012, G3 (Bethesda) 2(10): 1169--1178 Identification of Genes Underlying Hypoxia Tolerance in Drosophila by a P-element Screen. [FBrf0219647] Paik et al., 2012, Mech. Ageing Dev. 133(5): 234--245 Misexpression screen delineates novel genes controlling Drosophila lifespan. [FBrf0218389] Show all research papers ...