FlyBase Gene Report: Dmel\Oli

General Information

Symbol

Dmel\Oli

Species

D. melanogaster

Name

Olig family

Annotation Symbol

CG5545

Feature Type

protein_coding_gene

FlyBase ID

FBgn0032651

Gene Model Status

Current

Stock Availability

11 publicly available

Gene Snapshot

Contributions welcome

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Doli

Key Links

Genomic Location

Cytogenetic map

36D1-36D1

Sequence location

2L:17,589,184..17,591,267 [+]

Recombination map

2-53

RefSeq locus

NT_033779 REGION:17589184..17591267

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (8 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from biological aspect of ancestor with PANTHER:PTN001454287

(assigned by GO_Central )

(Gaudet et al., 2011)

enables protein dimerization activity

inferred from electronic annotation with InterPro:IPR011598

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

enables RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN001454287

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in motor neuron axon guidance

inferred from mutant phenotype

(Oyallon et al., 2012)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in neuron differentiation

inferred from biological aspect of ancestor with PANTHER:PTN001454287

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN001454287

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of transcription, DNA-templated

inferred from sequence or structural similarity with FLYBASE:cato; FB:FBgn0024249

(Peyrefitte et al., 2001)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN001454287

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS -: Basic helix-loop-helix (bHLH) transcription factors are sequence-specific DNA-binding proteins that regulate transcription. They are characterized by a 60 amino acid region comprising a basic DNA binding domain followed by a HLH motif formed from two amphipathic α-helices connected by a loop. bHLH transcription factors form homo- and hetero-dimeric complexes, which bind to a E box consensus sequence. (Adapted from PMID:15186484).

Summary (Interactive Fly)

HLH transcription factor expressed in the brain and CNS - motor neuron identify factor - regulates axon guidance

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Oli for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.55

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.50

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Oli-RA

FBtr0080986

NM_078868

1806

232

Oli-RB

FBtr0303252

NM_001201901

1174

232

Oli-RC

FBtr0303253

NM_001201902

1068

232

Oli-RD

FBtr0344781

NM_001299088

1392

232

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Oli-PA

FBpp0080539

24.1

232

10.65

NP_523592

AAF53631

Oli-PB

FBpp0292344

24.1

232

10.65

NP_001188830

ADV37079

Oli-PC

FBpp0292345

24.1

232

10.65

NP_001188831

ADV37080

Oli-PD

FBpp0311110

24.1

232

10.65

NP_001286017

AHN54531

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

232 aa isoforms: Oli-PA, Oli-PB, Oli-PC, Oli-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VJC1

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Oli using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

embryonic central brain neuron

(Fisher et al., 2012)

embryonic/larval nervous system

(Fisher et al., 2012)

lateral cord neuron

(Fisher et al., 2012)

ventral midline of embryo

(Fisher et al., 2012)

ventral nerve cord

(Fisher et al., 2012)

embryonic stage 10 -- 11

embryonic neuroblast | subset

(Zhang et al., 2008)

embryonic stage 10

neuroblast MP2

(Zhang et al., 2008)

embryonic stage 11

embryonic ganglion mother cell

(Zhang et al., 2008)

embryonic stage 11 -- 17

embryonic/larval central nervous system

(Zhang et al., 2008)

embryonic stage

ventral midline of embryo

(Wheeler et al., 2009)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 12 -- 15

ventral nerve cord

(Oyallon et al., 2012)

embryonic stage 12

ganglion mother cell | subset of ventral nerve cord

(Oyallon et al., 2012)

neuron | subset of ventral nerve cord

(Oyallon et al., 2012)

embryonic stage 16

neuron | subset of ventral nerve cord

(Oyallon et al., 2012)

embryonic stage 15

motor neuron | subset of ventral nerve cord

(Oyallon et al., 2012)

Additional Descriptive Data

Expression of Oli protein is detected in embryonic ganglion mother cells and in postmitotic neurons, the latter marked by hb and elav. Oli protein is also observed in a subset of ventral motor neurons, including some which exit the ventral nerve cord via the ISNb (marked by Btau\MAPT^{isl.H.T:Hsap\MYC}, Lim3^{T:Btau\MAPT,T:Hsap\MYC}, exex^Gal4 or vvl), TN or SNa (marked by Scer\GAL4^B-H1.B4.5) nerve branches.

(Oyallon et al., 2012)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Oli in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Oli

View exonic expression by tissue for Dmel\Oli

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0032651

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0032651

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG5545-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5545

Flygut - An atlas of the Drosophila adult midgut

FBgn0032651

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Oli

Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Oli

Transgenic constructs containing regulatory region of Oli

Deletions and Duplications ( 3 )

Disrupted in

Df(2L)Exel7069

(Ryder, 2004.4.26)

Df(2L)Exel9044

(Ryder, 2004.4.26)

Df(2L)Oli^Δ85

(Oyallon et al., 2012)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

Oli^Δ9

lethal (with Df(2L)Exel7069)

Oli^Δ9

lethal (with Df(2L)Exel9044)

Oli^Δ9

lethal (with Df(2L)H20)

Oli^Δ9

partially lethal | male limited, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

partially lethal | male limited | cold sensitive, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Oli^GD4381

viable, with Scer\GAL4^Mef2.PR

Oli^GD4381

viable, with Scer\GAL4^pnr-MD237

Oli^GD4381

viable, with Scer\GAL4^tin.CΔ4

Oli^GD4381

Other Phenotypes

Allele

flightless

Oli^Δ9

locomotor behavior defective | adult stage

Oli^Δ9

locomotor behavior defective | wandering third instar larval stage

Oli^Δ9

neuroanatomy defective | embryonic stage

Oli^Δ9

neuroanatomy defective | embryonic stage, with Scer\GAL4^elav-C155

Oli^UAS.cOa

neuroanatomy defective | embryonic stage, with Scer\GAL4^sca.PU

Oli^UAS.cOa

some die during embryonic stage

Oli^Δ9

visible | female limited, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

visible | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

Phenotype manifest in

Allele

abdominal intersegmental bidendritic neuron isbp | embryonic stage

Oli^Δ9

intersegmental nerve branch ISNb of A1-7 | embryonic stage

Oli^Δ9

intersegmental nerve branch ISNb of A1-7 | embryonic stage, with Scer\GAL4^elav-C155

Oli^UAS.cOa

intersegmental nerve branch ISNb of A1-7 | embryonic stage, with Scer\GAL4^sca.PU

Oli^UAS.cOa

transverse nerve | embryonic stage

Oli^Δ9

wing, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

wing | cold sensitive, with Scer\GAL4^Bx-MS1096

Oli^{UAS.ORF.GW.Tag:HA}

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (16)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\BHLHE22

12 of 15

Yes

Hsap\BHLHE23

12 of 15

Yes

Hsap\OLIG1

3 of 15

Yes

Hsap\OLIG2

3 of 15

Yes

Hsap\OLIG3

3 of 15

Yes

Hsap\NEUROD1

2 of 15

Yes

Hsap\NEUROD2

2 of 15

Hsap\NEUROD4

2 of 15

Yes

Hsap\NEUROD6

2 of 15

Yes

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (17)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Bhlhe22

11 of 15

Yes

Mmus\Bhlhe23

10 of 15

Yes

Mmus\Olig1

3 of 15

Yes

Mmus\Olig2

3 of 15

Yes

Mmus\Olig3

3 of 15

Yes

Mmus\Bhlha15

2 of 15

Mmus\Neurod1

2 of 15

Yes

Mmus\Neurod2

2 of 15

Mmus\Neurod4

2 of 15

Yes

Mmus\Neurod6

2 of 15

Yes

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (16)

Rnor\Bhlhe23

11 of 13

Yes

Rnor\Bhlhe22

7 of 13

Yes

Rnor\Olig1

3 of 13

Yes

Rnor\Olig2

3 of 13

Yes

Rnor\Olig3

3 of 13

Yes

Rnor\Bhlha15

2 of 13

Rnor\Neurod1

2 of 13

Yes

Rnor\Neurod4

2 of 13

Yes

Rnor\Neurod6

2 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (13)

Xtro\bhlhe22

5 of 12

Yes

Xtro\olig4

4 of 12

Yes

Xtro\olig2

3 of 12

Yes

Xtro\olig3

3 of 12

Yes

Xtro\neurod1

2 of 12

Yes

Xtro\neurod4

2 of 12

Yes

Xtro\neurod6

2 of 12

Yes

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (20)

Drer\bhlhe22

12 of 15

Yes

Drer\bhlhe23

12 of 15

Yes

Drer\si:ch211-196c10.13

5 of 15

Yes

Drer\olig4

4 of 15

Yes

Drer\olig1

3 of 15

Yes

Drer\olig2

3 of 15

Yes

Drer\bhlha15

2 of 15

Drer\neurod1

2 of 15

Yes

Drer\neurod2

2 of 15

Yes

Drer\neurod4

2 of 15

Yes

Drer\neurod6a

2 of 15

Yes

Drer\neurod6b

2 of 15

Yes

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (7)

Cele\hlh-32

10 of 15

Yes

Cele\hlh-17

9 of 15

Yes

Cele\hlh-31

9 of 15

Yes

Cele\hlh-16

2 of 15

Yes

Cele\cnd-1

1 of 15

Cele\ngn-1

1 of 15

Cele\Y7A9D.1

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190FMA )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA18959

Drosophila persimilis

Dper\GL14513

Drosophila willistoni

Dwil\GK18164

Drosophila virilis

Dvir\GJ17701

Drosophila mojavensis

Dmoj\GI17928

Drosophila grimshawi

Dgri\GH23918

Drosophila grimshawi

Dgri\GH11626

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150CFL )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17010798

Glossina morsitans

Tsetse fly

Gmor\GMOY005349

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_09041

Mayetiola destructor

Hessian fly

Mdes\Mdes004740

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL000341

Anopheles darlingi

American malaria mosquito

Adar\ADAC006720

Anopheles gambiae

Malaria mosquito

Agam\AGAP009227

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000843

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0AF2 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA003134

Danaus plexippus

Monarch butterfly

Dple\DPOGS201350-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL012384

Apis florea

Little honeybee

Aflo\2455924420

Apis mellifera

Western honey bee

Amel\GB45050

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP15131

Bombus terrestris

Buff-tailed bumblebee

Bter\15212403

Linepithema humile

Argentine ant

Lhum\LH22589

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0003e0

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG003274

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_08596

Tribolium castaneum

Red flour beetle

Tcas\TC014712

Pediculus humanus

Human body louse

Phum\PHUM507440

Rhodnius prolixus

Kissing bug

Rpro\RPRC001359

Cimex lectularius

Bed bug

Clec\CLEC012511

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI000347

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_13401

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0NKK )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR007739

Ixodes scapularis

Black-legged tick

Isca\ISCW009607

Stegodyphus mimosarum

African social velvet spider

Smim\KFM81184.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur13g02560

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_17020

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G129L )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Olig3

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Beta3b

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000027381

Gallus gallus

Domestic chicken

Ggal\OLIG3

Gallus gallus

Domestic chicken

Ggal\BHLHE23

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (8)

Gene Symbol

Score

Source

Alignment

3 of 10

net

3 of 10

tap

3 of 10

amos

2 of 10

ato

2 of 10

cato

1 of 10

sage

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

BHLHE22; basic helix-loop-helix family member e22

12 of 15

613483

BHLHE23; basic helix-loop-helix family member e23

12 of 15

609331

OLIG1; oligodendrocyte transcription factor 1

3 of 15

606385

OLIG2; oligodendrocyte transcription factor 2

3 of 15

606386

OLIG3; oligodendrocyte transcription factor 3

3 of 15

609323

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Oli - B-H2

two hybrid array

(Shokri et al., 2019)

Oli - CG31612

two hybrid array

(Shokri et al., 2019)

Oli - Dr

two hybrid array

(Shokri et al., 2019)

Oli - fd3F

two hybrid array

(Shokri et al., 2019)

Oli - vnd

anti tag coimmunoprecipitation, anti tag western blot

(Zhang et al., 2008)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Oli

enhanceable

exex

(Oyallon et al., 2012)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

exex

enhanceable

Oli

(Oyallon et al., 2012)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

61062

DroID - A comprehensive database of gene and protein interactions.

FBgn0032651

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

35066

MIST (protein-protein) - An integrated Molecular Interaction Database

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-53

Cytogenetic map

36D1-36D1

Sequence location

2L:17,589,184..17,591,267 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

36D1-36D1

Limits computationally determined from genome sequence between P{lacW}Aac11^k06710 and P{EP}CG10413^EP2164

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-53

(FlyBase, 2016)

2-52.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Bloomington

25341

w¹¹¹⁸; Mi{ET1}Oli^MB06951

42560

y¹ v¹; P{TRiP.HMJ02216}attP40

68192

y¹ w^*; PBac{Oli-GFP.FPTB}VK00033

59233

y¹ w^*; Mi{MIC}Oli^MI13928/SM6a

25979

y¹ v¹; P{TRiP.JF02001}attP2/TM3, Sb¹

FlyORF

F000021

M{UAS-Oli.ORF.3xHA.GW}ZH-86Fb

Kyoto

200692

w^*; P{GSV2}Oli^GS5080/SM1

VDRC

v104400

P{KK108335}VIE-260B

v13056

w¹¹¹⁸; P{GD4381}v13056

v13057

w¹¹¹⁸; P{GD4381}v13057/CyO

v341142

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00163}attP40/CyO-GFP

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (5)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH17679

Other clones

DPiM_GH17679

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0032651

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

LP18346

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0032651

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35066

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Oyallon et al., 2012)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Oli CG5545

(Moore et al., 2000)

Source for database merge of

Additional comments

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 42 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35066

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VJC1

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0032651

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0032651

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5545

Flygut - An atlas of the Drosophila adult midgut

FBgn0032651

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35066

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC014712

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG5545

modMine - A data warehouse for the modENCODE project

FBgn0032651

Linkouts

BioGRID - A database of protein and genetic interactions.

61062

DPiM - Drosophila Protein interaction map

FBgn0032651

DroID - A comprehensive database of gene and protein interactions.

FBgn0032651

DRSC - Results frm RNAi screens

FBgn0032651

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0032651

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG5545-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0032651

FlyMine - An integrated database for Drosophila genomics

FBgn0032651

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

35066

MIST (protein-protein) - An integrated Molecular Interaction Database

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG5545

(Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Stevens et al., 2008, Stevens et al., 2008, Ledent and Vervoort, 2001, Peyrefitte et al., 2001, Moore et al., 2000)

Doli

(Peyrefitte et al., 2001, Moore et al., 2000)

Oli

(Hao et al., 2020, Shokri et al., 2019, Losada-Perez, 2018, Charlton-Perkins et al., 2017, Chen et al., 2017, Schertel et al., 2015, Manning et al., 2012, Nfonsam et al., 2012, Wheeler et al., 2009, Peng et al., 2007, Brodsky et al., 2004)

Olig

(Zhang et al., 2008)

bHLHb23

(Stevens et al., 2008)

oli

(Eroglu et al., 2014, Oyallon et al., 2012)

Name Synonyms

Olig family

(Moore et al., 2000)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (56)

The following external sites may use different assemblies or annotations than FlyBase.

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