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Gene Dmel\CG7180

General Information
Symbol	Dmel\CG7180	Species	D. melanogaster
Name		Annotation symbol	CG7180
Feature type	protein_coding_gene	FlyBase ID	FBgn0032673
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	36E6-36E6	Sequence location	2L:18,180,996..18,184,630 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7180 (FBgn0032673). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein dephosphorylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult hindgut, adult heart, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628888_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG7180. Gene sequence location is 2L:18180996..18184630.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN30590 HFA03021 BKN60317 BKN45294 BKN60066
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 36E6-36E6   Limits computationally determined from genome sequence between P{lacW}Aac11k06710 and P{EP}CG10413EP2164
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7180 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7180-RA FBtr0081061  NM_136028   3413   682
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7180-PA   FBpp0080614   78.9   682   8.62     NP_609872   AAF53658
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase, receptor/non-receptor type (IPR000242) Protein-tyrosine/Dual-specificity phosphatase (IPR000387) Protein-tyrosine phosphatase, active site (IPR016130)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53658   AY071625 AAL49247   AY095518   BF489599   BI214034   BI484385   BI580578   BI612420   CO285068   CO285069   CO294356   CO301070   CO305572   CO321078   CO322282   CO328388   CO340718   EC061124   EC062352   EC062370   EC062513   EC065968   EC075406   EC203113   EC211927   EC217075   EC251591   EC257081   GH749217   GH749341   GH752243   GH753568   GH754506   GH754971   GH757566   GH757734   GH772046   GH773770   GH773864   GH777892   GH778461   GH780248   GH781197   GH783307   GH792569   GH794249   GH796123   GH796980   GH797041   GH797330   GH797420   GH797589   GH798099   GH798257   GH799068   GH799796   GH799927   GH799953   GH800466   GH801350   GH801628   GH801786   GH802255   GH804741   GH806339   GH807865   GH808239   GH810907   GH813460   GH814772   GH815159   GH815160   GH816341   GH816649   GH816835   GH818065   GH818109   GH821002   GH821415   GH823546   GH824910   GH825469   GH826037   GH827081   GH827324   GH830768   GH832449   GH833438   GH833463   GH834050   GH836673   GH838001   GH838177   GH844632   GH846283   GH846292   GH846320   GH850516   GH851868   GH852587   GH853876   GH853891   GH853966   GH857328   GH858125   GH858193   GH858557   GH858599   GH859868   GH860835   GH861438   GH861729   GH864625   GH865100   GH866373   GH867631   GH868526   GH869652   GH869835   GH870525   GH870885   GH872411   GH873480   GH874278   GH874510   GH875273   GH876309   GH876384   GH879932   GH882152   GH882594   GH883206   GH884778   GH885100   GH886652   GH889318   GH890458   GH890711   GH891113   GH891323   GH892323   GH892688   GH892761   GH895674   GH898665   GH899245   GH899611   GH900598   GH908610   GH910401   GH911485   GH912854   GH913663   GH913826   GH917638   GH923079   GH923142   GH926222   GH927511   GH929616   GH929884   GH932656   GH932743   GH935645   GH936619   GH937381   GH938083   GH938797   GH939477   GH939823   GH941028
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SWR7 Q9VJ95
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032673    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032673 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032673 expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr  (283) embryo 12-14hr  (365) embryo 14-16hr  (612) embryo 16-18hr  (725) embryo 18-20hr  (848) embryo 20-22hr  (1079) embryo 22-24hr  (1385) larva L1  (1186) larva L2  (624) larva L3 12hr old  (565) larva L3 puffstage 1-2  (309) larva L3 puffstage 3-6  (489) larva L3 puffstage 7-9  (1192) white prepupae new  (2820) white prepupae 12hr  (1352) white prepupae 24hr  (299) pupae 2d postWPP  (504) pupae 3d postWPP  (538) pupae 4d postWPP  (6218) adult male 01day  (1440) adult male 05day  (1470) adult male 30day  (1432) adult female 01day  (878) adult female 05day  (227) adult female 30day  (200) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new  (2820) white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP  (6218) adult male 01day  1440 adult male 05day  1470 adult male 30day  1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032673 expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr  (283) embryo 12-14hr  (365) embryo 14-16hr  (612) embryo 16-18hr  (725) embryo 18-20hr  (848) embryo 20-22hr  (1079) embryo 22-24hr  (1385) larva L1  (1186) larva L2  (624) larva L3 12hr old  (565) larva L3 puffstage 1-2  (309) larva L3 puffstage 3-6  (489) larva L3 puffstage 7-9  (1192) white prepupae new  (2820) white prepupae 12hr  (1352) white prepupae 24hr  (299) pupae 2d postWPP  (504) pupae 3d postWPP  (538) pupae 4d postWPP  (6218) adult male 01day  (1440) adult male 05day  (1470) adult male 30day  (1432) adult female 01day  (878) adult female 05day  (227) adult female 30day  (200) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new  (2820) white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP  (6218) adult male 01day  1440 adult male 05day  1470 adult male 30day  1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    5 embryo 04-06hr    3 embryo 06-08hr    18 embryo 08-10hr    34 embryo 10-12hr    283 embryo 12-14hr    365 embryo 14-16hr    612 embryo 16-18hr    725 embryo 18-20hr    848 embryo 20-22hr    1079 embryo 22-24hr    1385 larva L1    1186 larva L2    624 larva L3 12hr old    565 larva L3 puffstage 1-2    309 larva L3 puffstage 3-6    489 larva L3 puffstage 7-9    1192 white prepupae new    2820 white prepupae 12hr    1352 white prepupae 24hr    299 pupae 2d postWPP    504 pupae 3d postWPP    538 pupae 4d postWPP    6218 adult male 01day    1440 adult male 05day    1470 adult male 30day    1432 adult female 01day    878 adult female 05day    227 adult female 30day    200 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032673    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032673 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult hindgut, adult heart, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032673 expression level Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain  513.1 Adult Thoracic-Abdominal Ganglion  (641.3) Adult Crop  (752.9) Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032673 expression level Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain  513.1 Adult Thoracic-Abdominal Ganglion  641.3 Adult Crop  752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.475 Larval Midgut    47.7 Larval Hindgut    91 Larval Malpighian Tubules    7.6 Larval Fat Body    1.8 Larval Salivary Gland    1.8 Larval Trachea    7.25 Larval Carcass    266.425 Adult Head    214.1 Adult Eye    227.8 Adult Brain    513.1 Adult Thoracic-Abdominal Ganglion    641.3 Adult Crop    752.9 Adult Midgut    63.8 Adult Hindgut    106.3 Adult Malpighian Tubules no informative data Adult Fat Body    9.1 Adult Salivary Gland    9.9 Adult Heart    273.1 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    6.3 Adult Ovary    4.8 Adult Testis    22.7 Adult Male Accessory Gland    79.6 Adult Carcass    241.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    214.1   NA  Eye    227.8   NA  Brain    513.1   163.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    641.3   NA  Crop    752.9   47.7  Midgut    63.8   91  Hindgut    106.3   7.6  Malpighian Tubules    no informative data   1.8  Fat Body    9.1   1.8  Salivary Gland    9.9   NA  Heart    273.1   7.25  Trachea    NA   NA  VirginFemale Spermatheca    4.3   NA  InseminatedFemale Spermatheca    6.3   NA  Ovary    4.8   NA  Testis    22.7   NA  Male Accessory Gland    79.6   266.425  Carcass    241.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032673 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7180-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG7180GD10766 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG7180 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7180 Class Mutagen Stocks Known lesion CG7180GD10766 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG7180KK110590 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel8038 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10766} NA P{KK110590} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
protein tyrosine phosphatase activity inferred from sequence or structural similarity with UniProtKB:Q15262 (FlyBase, 1992-) non-traceable author statement (Morrison et al., 2000)
Biological Process
CV term Evidence References
protein dephosphorylation inferred from sequence or structural similarity with UniProtKB:Q15262 (FlyBase, 1992-) non-traceable author statement (Morrison et al., 2000)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7180 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61087 DroID - A comprehensive database of gene and protein interactions. • FBgn0032673 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35091
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs	Dpse\GA20160
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL003307-PA Aedes aegypti (mosquito) AAEL014181-PA Aedes aegypti (mosquito) AGAP008077-PA Anopheles gambiae (mosquito) XP_396411.3 Apis mellifera (honey bee) XP_001948729.1 Acyrthosiphon pisum (pea aphid) 243882 Branchiostoma floridae (lancelet) XP_001894311.1 Brugia malayi (roundworm nematode) BGIBMGA004537-PA Bombyx mori (silk worm) CN07054 Caenorhabditis brenneri (small nematode) CBP32913 Caenorhabditis briggsae (nematode) CE42278 Caenorhabditis elegans (worm) ENSCINP00000005095 Ciona intestinalis (sea squirt) JA17530 Caenorhabditis japonica (nematode) ENSCPOP00000020228 Cavia porcellus (guinea pig) RP28725 Caenorhabditis remanei (nematode) ENSCSAVP00000004978 Ciona savignyi (sedentary tunicate) 136827 Capitella spl (polychaete worm) 307309 Daphnia pulex (daphnia) ENSDARP00000005710 Danio rerio (zebra fish) ENSGACP00000003485 Gymnopilus aculeatus (mushroom) ENSGALP00000025727 Gallus gallus (chicken) 140014 Hypsipyla robusta (cedar shoot borer) ISCW018133-PA Ixodes scapularis (deer tick) 152052 Lottia gigantea (owl limpet) ENSMODP00000006668 Monodelphis domestica (gray opossum) ENSMUSP00000076533 Mus musculus (house mouse) 92641 Nematostella vectensis (starlet anemone) XP_001606669.1 Nasonia vitripennis (wasp) ENSORLP00000012465 Oryzias latipes (japanese killifish) PHUM000824-PA Pediculus humanus (human body louse) PP07846 Pristionchus pacificus (nematode) ENSPPYP00000001877 Pongo pygmaeus (orangutan) XP_001183865.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001187151.1 Strongylocentrotus purpuratus (purple sea urchin) 27423 Trichoplax adhaerens (metazoa) XP_973238.2 Tribolium castaneum (red flour beetle) ENSTNIP00000002429 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000013701 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038993 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16552 LH15060 ISCW018133 FBgn0230461 FBgn0216586 FBgn0206990 FBgn0172007 JGI_V11_307309 FBgn0157035 FBgn0143602 FBgn0118021 FBgn0091881 CPIJ001889 BGIBMGA001962 ACYPI002533 GB11835 AGAP008077 AAEL014181 AAEL003307 PB22165 PHUM370500 GLEAN_09173
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v102397 P{KK110590}VIE-260B v34369 w1118; P{GD10766}v34369 v34368 w1118; P{GD10766}v34368/TM3
Genomic Clones ( 1 )
	BACR39D12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 169 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH22607 RE67475
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT25678 RE19727 RE74789 RH40882
Other clones	17588 52582 52778 54647 62864 76617 120699 146289 214215.23 214535.33 CK01.114D.B8 EK168128 EK168129 EK180016 EK187815 EK206710 EK248960 EK290255 EP09123 EP11213 RP003007000 RP003008566 RP003013076 RP003023685 RP003033505 RP003038417 RP003039117 RP003040422 RP003041380 RP003051475 RP003054490 RP003054783 RP003059398 RP003074273 RP003095054 RP003096312 RP003110247 RP003115198 RP003115804 RP003117193 RP003117782 RP003120062 RP003132872 RP003133053 RP003136754 RP003136881 RP003138912 RP003147236 RP003152599 RP003155815 RP003156755 RP003157220 RP003159085 RP003168261 RP003174292 RP003176156 RP003176478 RP003181393 RP003185021 RP003193946 RP003195832 RP003201484 RP003202379 RP003212033 RP003212350 RP003213462 RP003215020 RP003217768 RP003229160 RP003230394 RP003237615 RP003240731 RP003245261 RP003245706 RP003246534 RP003257397 RP003264159 RP003264385 RP003266032 RP003266678 RP003268783 RP003268819 RP003277692 RP003290082 RP003291001 RP003299246 RP003301374 RP003301977 RP003305664 RP003314011 RP003317385 RP003323301 RP003326441 RP003328514 RP003328657 RP003328848 RP003328993 RP003339395 RP003339975 RP003341624 RP003359683 RP003380830 RP003383273 RP003396115 RP003403167 RP003411106 RP003412276 RP003416071 RP003416559 RP003440343 RP003443522 RP003454322 RP003455449 RP003457236 RP003479528 RP003484416 RP003486933 RP003487606 RP003491016 RP003494128 RP003510403 RP003520830 RP003537261 RP003540052 RP003546715 RP003550598 RP003558938 RP003566089 RP003566854 RP003569724 RP003580162 RP003581539 RP003581912 RP003584769 RP003585071 RP003586925 RP003587612 RP003591628 RP003593156 RP003593725 RP003593960 RP003594042 RP003601057 RP003602699 RP003603991 RP003614858 RP003615001 RP003615227 RP003617018 RP003619954 RP003622417 RP003623101 RP003625858 RP003628488 RP003628735 RP003631371 RP003646531 RP003650320 RP003652738 RP003655304 RP003663314 RP003666090 RP003678555
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032673 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35091
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136028 RefSeq (Proteins) • NP_609872 DDBJ / EMBL / GenBank • AAF53658 AAL49247 AY071625 BI484385 Entrez Gene - A searchable database of RefSeq genes. • 35091 UniProtKB/TrEMBL • Q8SWR7 Q9VJ95
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase, receptor/non-receptor type (IPR000242) Protein-tyrosine/Dual-specificity phosphatase (IPR000387) Protein-tyrosine phosphatase, active site (IPR016130)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61087 DroID - A comprehensive database of gene and protein interactions. • FBgn0032673 DRSC - Results from RNAi screens. • FBgn0032673 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032673 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7180-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032673 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35091 InParanoid A subset of ortholog calls from InParanoid. • AAEL003307-PA Aedes aegypti (mosquito) AAEL014181-PA Aedes aegypti (mosquito) AGAP008077-PA Anopheles gambiae (mosquito) XP_396411.3 Apis mellifera (honey bee) XP_001948729.1 Acyrthosiphon pisum (pea aphid) 243882 Branchiostoma floridae (lancelet) XP_001894311.1 Brugia malayi (roundworm nematode) BGIBMGA004537-PA Bombyx mori (silk worm) CN07054 Caenorhabditis brenneri (small nematode) CBP32913 Caenorhabditis briggsae (nematode) CE42278 Caenorhabditis elegans (worm) ENSCINP00000005095 Ciona intestinalis (sea squirt) JA17530 Caenorhabditis japonica (nematode) ENSCPOP00000020228 Cavia porcellus (guinea pig) RP28725 Caenorhabditis remanei (nematode) ENSCSAVP00000004978 Ciona savignyi (sedentary tunicate) 136827 Capitella spl (polychaete worm) 307309 Daphnia pulex (daphnia) ENSDARP00000005710 Danio rerio (zebra fish) ENSGACP00000003485 Gymnopilus aculeatus (mushroom) ENSGALP00000025727 Gallus gallus (chicken) 140014 Hypsipyla robusta (cedar shoot borer) ISCW018133-PA Ixodes scapularis (deer tick) 152052 Lottia gigantea (owl limpet) ENSMODP00000006668 Monodelphis domestica (gray opossum) ENSMUSP00000076533 Mus musculus (house mouse) 92641 Nematostella vectensis (starlet anemone) XP_001606669.1 Nasonia vitripennis (wasp) ENSORLP00000012465 Oryzias latipes (japanese killifish) PHUM000824-PA Pediculus humanus (human body louse) PP07846 Pristionchus pacificus (nematode) ENSPPYP00000001877 Pongo pygmaeus (orangutan) XP_001183865.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001187151.1 Strongylocentrotus purpuratus (purple sea urchin) 27423 Trichoplax adhaerens (metazoa) XP_973238.2 Tribolium castaneum (red flour beetle) ENSTNIP00000002429 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000013701 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038993 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35091 modMine - Data generated by the modENCODE project. • FBgn0032673 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16552 LH15060 ISCW018133 FBgn0230461 FBgn0216586 FBgn0206990 FBgn0172007 JGI_V11_307309 FBgn0157035 FBgn0143602 FBgn0118021 FBgn0091881 CPIJ001889 BGIBMGA001962 ACYPI002533 GB11835 AGAP008077 AAEL014181 AAEL003307 PB22165 PHUM370500 GLEAN_09173
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG7180 (Keleman et al., 2009.8.5) R-PTPk (Morrison et al., 2000)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231] Morrison et al., 2000, J. Cell Biol. 150(2): Table S1. Drosophila protein kinases and phosphatases. [FBrf0132098]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Dunn, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126662]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]